The Lancet Neurology in conversation with - podcast cover

The Lancet Neurology in conversation with

The Lancet Grouplancetneur.podbean.com

Explore the latest breakthroughs in brain health and neurological disease through interviews with leading researchers, neurologists, and policy experts. Each episode breaks down complex topics for a broad audience, translating cutting-edge science into practical insights.

Editors at The Lancet Neurology, the world-leading clinical neurology journal, interview the investigators at the forefront of stroke, Alzheimer’s disease, epilepsy, migraine, Parkinson’s disease, multiple sclerosis, sleep disorders, traumatic brain injury, and other neurological challenges.

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Episodes

Njideka Okubadejo and Mie Rizig on Parkinson’s disease in African and African admixed populations

Njideka Okubadejo and Mie Rizig join The Lancet Neurology to discuss their comprehensive genome-wide assessment in African and African admixed individuals with the aim of developing a better understanding of the genetic architecture of Parkinson's disease in these underserved populations. Read the full article: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(23)00283-1/fulltext?dgcid=buzzsprout_icw_podcast_generic_laneur Medical imaging and theranostics are revolutionising how we...

Oct 20, 202327 min

Anthony Feinstein on a trial of cognitive rehabilitation and exercise in people with progressive multiple sclerosis

Anthony Feinstein (University of Toronto and Sunnybrook Health Sciences Centre, Toronto, Canada) discusses CogEx, a randomised trial of cognitive rehabilitation and aerobic exercise for cognitive impairment in people with progressive multiple sclerosis. The Article is published in the October issue of The Lancet Neurology . Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announce the launch of,...

Sep 20, 202316 min

William Jagust on amyloid β and cognition

William Jagust (University of California in Berkeley, CA, USA) talks to Senior Editor Sarah Passey about the complex pathway between amyloid β and cognition, and implications for therapy for people with Alzheimer’s disease. His Personal View on this topic is published in the September issue of The Lancet Neurology . Read the full article: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(23)00128-X/fulltext?dgcid=buzzsprout_icw_podcast_generic_laneur Medical imaging and theranostic...

Aug 16, 202314 min

Stephen Strittmatter on a first-in-human trial for treating chronic cervical spinal cord injury

Stephen Strittmatter (Yale School of Medicine, CT, USA) discusses his first-in-human and randomised trial of a soluble Nogo-receptor-Fc decoy in patients with chronic cervical spinal cord injury. The Article is published in the August issue of The Lancet Neurology . Read the full article: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(23)00215-6/fulltext?dgcid=buzzsprout_icw_podcast_generic_laneur Medical imaging and theranostics are revolutionising how we diagnose, treat, and u...

Jul 19, 202315 min

Benzi Kluger, Claire Creutzfeldt, and Malenna Sumrall on palliative care for individuals with neurological diseases

Benzi Kluger (University of Rochester Medical Center, Rochester, NY, USA), Claire Creutzfeldt (University of Washington, Seattle, WA, USA), and Malenna Sumrall (University of Colorado Anschutz Medical Campus, Aurora, CO, USA) join Jonathan Blott to discuss palliative care for individuals with neurological diseases, exploring the challenges and opportunities in enhancing the quality of life for those affected by neurological conditions. Their Review is published in the July issue of The Lancet Ne...

Jun 21, 202318 min

Andrew Cole on the complexities underlying epilepsy in people with glioblastoma

Andrew Cole (Massachusetts General Hospital Epilepsy Service, Boston, MA, USA) talks to Senior Editor Sarah Passey about the complexities underlying epilepsy in people with glioblastoma. His Review on this topic is published in the June issue of The Lancet Neurology. Read the full article here: thelancet.com/journals/laneur/article/PIIS1474-4422(23)00031-5/fulltext?dgcid=buzzsprout_icw_podcast_laneur Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand dise...

May 18, 202320 min

Karen Duff and Connor Langworth-Green on tauopathies and chronic inflammation

Karen Duff and Connor Langworth-Green (University College London, London, UK) discuss tauopathies and the chronic effects of inflammation on this group of disorders. Their Personal View on this topic is published in the May issue of The Lancet Neurology. Read the Personal View here: Chronic effects of inflammation on tauopathies Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announce the launc...

Apr 13, 202316 min

Kerstin Hellwig on family planning considerations in MS

Kerstin Hellwig (Ruhr University Bochum, Bochum, Germany) discusses family planning considerations in multiple sclerosis. This Review is published in the April issue of The Lancet Neurology . Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announce the launch of, The Lancet Medical Imaging and Theranostics. You can visit https://www.thelancet.com/medical-imaging-theranostics to learn more. Cont...

Mar 15, 202315 min

Geraldine Dawson on advances in the prediction of autism during infancy

Geraldine Dawson (Duke University School of Medicine, NC, USA ) discusses the latest advances and ongoing challenges in prediction of autism during infancy. This Review is published in the March issue of The Lancet Neurology . Read the full article: Prediction of autism in infants: progress and challenges Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announce the launch of, The Lancet Medical...

Feb 16, 202325 min

Ellisiv Mathiesen on tenecteplase for patients with wake-up stroke

Ellisiv Mathiesen (The University of Tromsø – the Arctic University of Norway, Tromsø, Norway) discusses the findings of the TWIST trial, which investigated the use of tenecteplase for patients with wake-up stroke who were selected for treatment by non-contrast CT. This Fast-track Article is published in the February issue of The Lancet Neurology . Read the full article: Safety and efficacy of tenecteplase in patients with wake-up stroke assessed by non-contrast CT (TWIST) Medical imaging and th...

Jan 19, 202310 min

Beau Ances on amyloid biomarkers in Alzheimer’s

Beau Ances (Washington University in St Louis, MO, USA) discusses recent research on amyloid biomarkers in people with genetic forms of Alzheimer’s disease; his Article is published in the January issue of The Lancet Neurology . Read the full article: Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group ...

Dec 12, 202212 min

Axel Petzold on the diagnosis and classification of optic neuritis

Axel Petzold (National Hospital for Neurology and Neurosurgery and Moorfields Eye Hospital, London, UK, and Amsterdam University Medical Center, Amsterdam, Netherlands) discusses a Position Paper, published in the December issue of The Lancet Neurology, which sets out new criteria for the diagnosis and classification of optic neuritis. Read the Position Paper: Diagnosis and classification of optic neuritis Medical imaging and theranostics are revolutionising how we diagnose, treat, and understan...

Nov 16, 202221 min

Maeike Zijlmans on using biomarkers to tailor epilepsy surgery

Maeike Zijlmans (University Medical Center Utrecht, Utrecht, Netherlands) discusses recent research on tailoring of epilepsy surgery with biomarkers on intraoperative electrocorticography, and describes some of the challenges of this technique and what the future steps are for the field; the Article is published in the November issue of The Lancet Neurology . Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group...

Oct 18, 202216 min

Jerome Siegel on sleep habits

Jerome Siegel (University of California, Los Angeles, CA, USA) discusses sleep research in hunter-gatherer populations and what we can learn from the sleep habits of various species; his Review is published in the October issue of The Lancet Neurology , which is the fourth paper in The Lancet ’s Series on sleep and sleep disorders. Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announce the la...

Sep 14, 202245 min

Laurent Servais and Dora Markati on emerging therapies for Duchenne muscular dystrophy

Laurent Servais and Dora Markati (both from the University of Oxford, UK) discuss emerging therapies for Duchenne muscular dystrophy; their Review is published in the September issue of The Lancet Neurology . Read the full Review: Emerging therapies for Duchenne muscular dystrophy Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announce the launch of, The Lancet Medical Imaging and Theranostics...

Aug 10, 202218 min

Andreas Charidimou on new criteria for diagnosis of cerebral amyloid angiopathy

Andreas Charidimou (Massachusetts General Hospital, Boston, MA, USA) discusses an international collaborative study that presents new Boston criteria for diagnosis of cerebral amyloid angiopathy; the Article is published in the August issue of The Lancet Neurology. Read the full article: The Boston criteria version 2.0 for cerebral amyloid angiopathy Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy...

Jul 13, 202224 min

Sarah Tabrizi and Cristina Sampaio on classifying Huntington’s and new therapies

Sarah Tabrizi (UCL Queen Square Institute of Neurology, London, UK) and Cristina Sampaio (CHDI Foundation, Princeton, NJ, USA) discuss two papers on Huntington’s disease published in the July issue of The Lancet Neurology : a Position Paper outlining a new classification of the disease, called the Huntington’s Disease Integrated Staging System, and a Personal View on potential disease-modifying therapies. Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand...

Jun 15, 202220 min

Mark Hallett on functional neurological disorder

Mark Hallett (National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA) discusses his Review, published in the June issue of The Lancet Neurology , on functional neurological disorder, and talks about new subtypes of this disorder, diagnostic challenges, and how education is important. Read the full article: Functional neurological disorder: new subtypes and shared mechanisms Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To...

May 13, 202210 min

Eva Feldman on advances in understanding ALS

Eva Feldman (University of Michigan, Ann Arbor, USA) discusses the latest advances in the genetics, risk factors, pathophysiology, therapeutic development, and the diagnosis and prognosis of amyotrophic lateral sclerosis; the Series is published in the May issue of The Lancet Neurology . Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announce the launch of, The Lancet Medical Imaging and Thera...

Apr 13, 202224 min

Estrella Morenas-Rodriguez and Christian Haass on soluble TREM2 and Alzheimer’s

Estrella Morenas-Rodriguez and Christian Haass (German Centre for Neurodegenerative Diseases, Munich, Germany) discuss their recent research, published in the April issue of The Lancet Neurology , on soluble TREM2 and its association with Alzheimer’s disease biomarkers and cognition. Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announce the launch of, The Lancet Medical Imaging and Theranost...

Apr 06, 202228 min

John Collinge on a treatment for CJD

John Collinge (MRC Prion Unit, University College London, London, UK) discusses a first-in-human treatment programme to give PRN100, an anti-prion-protein monoclonal antibody, to patients with Creutzfeldt–Jakob disease; the report is published in the April issue of The Lancet Neurology. Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announce the launch of, The Lancet Medical Imaging and Theran...

Mar 16, 202216 min

Alexandra Durr on riluzole in patients with spinocerebellar ataxia type 2

Alexandra Durr (Paris Brain Institute, Pitié-Salpêtrière Paris, France) discusses the ATRIL study, a randomised trial of riluzole in patients with spinocerebellar ataxia type 2, which is published in the March issue of The Lancet Neurology . Read the full article: Safety and efficacy of riluzole in spinocerebellar ataxia type 2 in France (ATRIL) Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to a...

Feb 22, 20229 min

Giuseppe Citerio on frailty and TBI

Giuseppe Citerio (University of Milano-Bicocca, Milan, Italy) discusses the implications of a study from the CENTER-TBI project of the effect of frailty on 6-month outcome after traumatic brain injury, which is published in the February issue of The Lancet Neurology . Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announce the launch of, The Lancet Medical Imaging and Theranostics. You can vis...

Jan 19, 202210 min

Alberto Costa on memantine in adolescents and young adults with Down syndrome

Alberto Costa (Case Western Reserve University, Cleveland, OH, USA) discusses his study on the use of memantine in adolescents and young adults with Down syndrome, which is published in the January issue of The Lancet Neurology . Read the full article: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(21)00369-0/fulltext Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announce the...

Dec 20, 202116 min

Olivier Rascol on amantadine for patients with movement disorders

Olivier Rascol (Toulouse University, France) discusses the uses of amantadine in the treatment of patients with movement disorders, which are the focus of his Personal View in the December issue of The Lancet Neurology . Read the full article: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(21)00249-0/fulltext Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announce the launch o...

Nov 17, 202129 min

Antonio Uccelli on stems cells for MS

Antonio Uccelli (University of Genoa) discusses his research, published in the November issue of The Lancet Neurolog y, on the therapeutic use of mesenchymal stem cells for multiple sclerosis. Read the full article: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(21)00301-X/fulltext Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announce the launch of, The Lancet Medical Imagin...

Oct 20, 202119 min

Priya Palta on blood pressure control and cognitive decline

Priya Palta (Columbia University, New York) explains the importance of blood pressure control in the prevention of cognitive decline. Her Review, published in the October issue of The Lancet Neurology , provides an update of the mounting evidence that links hypertension with dementia risk. Read the full article: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(21)00248-9/fulltext Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. T...

Sep 15, 202118 min

Adam Boxer on tau biomarkers

Adam Boxer (University of California, San Francisco) discusses his research, published in August issue of The Lancet Neurology , on diagnostic performance of tau biomarkers in neurodegenerative diseases. Read the full article: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(21)00214-3/fulltext Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announce the launch of, The Lancet Med...

Aug 18, 202113 min

Irene Cortese on the difficulties of designing clinical trials

Irene Cortese (National Institute of Neurological Disorders and Stroke) discusses the difficulties of designing clinical trials in progressive multifocal leukoencephalopathy and talks about a pilot study of virus-specific T cells for treatment of this population, published in the August issue of The Lancet Neurology. Read the full article: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(21)00174-5/fulltext Medical imaging and theranostics are revolutionising how we diagnose, trea...

Jul 21, 202111 min

Doug Turnbull on mitochondrial diseases in adults

Doug Turnbull (University of Newcastle) discusses mitochondrial diseases in adults, which are reviewed in the July issue of The Lancet Neurology , and explains how important these diseases are for neurologists. Read the full article: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(21)00098-3/fulltext Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announce the launch of, The Lan...

Jun 16, 202121 min
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