Guest: Dr. Siobhan Burns is a Professor of Translational Immunology at University College London. Her group studies the underlying molecular and cellular mechanisms that give rise to primary immunodeficiency disorders. She talks about how genetic mutations affect immune function, and what inborn errors of immunity can teach us about general immunology. Featured Products and Resources: Check out the program for IUIS 2023! Keep current with the latest in human immunology news. The Immunology Scien...
Oct 24, 2023•1 hr 2 min
Guest: Dr. Peter Fecci is a Professor of Neurosurgery at Duke University and the Director of the Duke Center for Brain and Spine Metastasis . His research focuses on brain tumor immunology and immunotherapy, and T cell dysfunction in glioblastoma and other intracranial cancers. He talks about activating T cells to target brain tumors and his team’s work on targeting MHC-I-negative tumor cells . Featured Products and Resources: Register now for the International Congress of Immunology in South Af...
Oct 10, 2023•1 hr 8 min
Guest: Dr. Alice Long is an Associate Member and Principal Investigator at Benaroya Research Institute at Virginia Mason, where her lab focuses on discovering how tolerance is lost in human autoimmunity and how therapy can restore tolerance. Featured Products and Resources: Attend IUIS 2023, the world’s leading conference in the field of immunology. Keep current with Immune Regulation News The Immunology Science Round Up Insights into B Cell Selection – Antigen-presenting autoreactive B cells pl...
Sep 26, 2023•1 hr
Guest: Dr. Kristin Anderson is an Assistant Professor at the University of Virginia, where her lab focuses on engineering T cells to overcome immune suppression in the tumor microenvironment. She talks about how her cancer diagnosis changed her career focus, strategies for targeting ovarian cancer, and her transition from postdoc to professor. Featured Products and Resources: Register now for IUIS 2023! Support the culture of human T cells and enhance your cell therapy development by using high-...
Sep 12, 2023•1 hr 10 min
Guest: Dr. Vinod Blachandran is an Attending Surgeon and Lab Head at Memorial Sloan Kettering Cancer Center. He talks about neoantigen vaccines for pancreatic cancer , what can be learned from a rare group of long-term survivors, and how surgeon-scientist mentors have influenced his career. Featured Products and Resources: Stay up-to-date with the latest in pancreatic cell news. Register for IUIS 2023! The Immunology Science Round Up Platelet Factors in Aging – Platelet factors transfer the bene...
Aug 29, 2023•1 hr 8 min
Guest: Dr. Greg Delgoffe is an Associate Professor at the University of Pittsburgh. His lab studies the intersection of metabolism and immunity in cancer. He talks about the metabolism of immune cells in cancer and the effects of nutrients in the tumor microenvironment. Featured Products and Resources: Register for IUIS 2023! Download a free wallchart on the production of CAR T cells. The Immunology Science Round Up Microbes in Diabetes Drug Responses – Researchers identified a microbiota-derive...
Aug 15, 2023•1 hr 14 min
Guest: Dr. Daniel Streicker is a Professor of Viral Ecology at the University of Glasgow, where his lab investigates pathogen transmission between species. He talks about vampire bats as a reservoir for rabies and approaches to vaccination that could prevent transmission. Featured Products and Resources: Register for IUIS 2023 in Cape Town, South Africa. Keep current with the latest infectious disease news. The Immunology Science Round Up Sleep Disturbance in Cardiac Disease – Sleep disruption i...
Aug 01, 2023•1 hr 1 min
Guest: Dr. Jamie Spangler is an Assistant Professor at Johns Hopkins. Her lab implements a unique structure-based engineering approach to elucidate the determinants of protein activity and inform drug development. She talks about designing cytokine mimetics and how engineered cytokines could be used as therapeutics. Featured Products and Resources: Register for IUIS 2023. Activate, expand, and differentiate with cytokines, chemokines, and growth factors. The Immunology Science Round Up Microenvi...
Jul 18, 2023•1 hr 10 min
Guests: Dr. Laura Raff is Associate Director, Sales, Immunology and Dr. Ami Ashar-Patel is a Senior Account Manager, Immunology at STEMCELL Technologies. Dr. Raff has a PhD in Molecular Microbiology and Immunology from the University of Southern California and Dr. Ashar-Patel has a PhD in Biochemistry and Molecular Pharmacology from the University of Massachusetts Chan Medical School. They talk about their career transitions from academia to industry and how they support scientists’ research end...
Jul 04, 2023•1 hr
Guest: Dr. Alessandro Sette is a Center Head, Division Head, and Professor at the La Jolla Institute of Allergy and Immunology. His lab focuses on understanding the immune response, measuring immune activity, and developing disease intervention strategies against cancer, autoimmunity, allergy, and infectious diseases. He talks about bringing a biotech mindset back to academia, cross-reactive T cell responses to SARS-CoV-2 , and compiling an immune-epitope database . Featured Products and Resourc...
Jun 20, 2023•1 hr 14 min
In May 2023, we attended IMMUNOLOGY2023, the annual meeting of the American Association of Immunologists, in Washington, DC. We spoke with delegates about their research and impressions of the meeting, including their reasons for attending, what they were most looking forward to, and the most memorable research presented. Featured Products and Resources: Register for the International Union of Immunological Societies 2023 Congress in Cape Town, South Africa from November 27 to December 2. Prepar...
Jun 06, 2023•53 min
Guest: Dr. Bana Jabri is the Sarah and Harold Lincoln Thompson Professor in the Department of Medicine and the Research Director of the Celiac Disease Center at the University of Chicago. Her research focuses on innate and mucosal immunity, particularly in celiac disease, autoimmune disorders, and inflammatory bowel disease. She talks about the mechanisms of celiac disease and new treatment options. She also discusses how the microbiome can affect immune responses in cancer. Featured Products an...
May 23, 2023•1 hr 7 min
In May 2023, we attended IMMUNOLOGY2023, the annual meeting of the American Association of Immunologists in Washington, DC, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the final of five special episodes from the meeting. Brenda and Jason talk about sessions on mucosal immunity, emerging pathogens, and having a successful postdoctoral experience. Highlights include Dr. Isaac Chiu ‘s talk on pain and mucus production in the gut, Dr. James Crowe ‘s talk on mo...
May 16, 2023•19 min
In May 2023, we attended IMMUNOLOGY2023, the annual meeting of the American Association of Immunologists in Washington, DC, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the fourth of five special episodes from the meeting. Brenda and Jason talk about micelles for drug delivery and how helminth infection affects susceptibility to SARS-CoV-2. Featured Products and Resources: Explore Free Immunology Wallcharts Subscribe to our newsletter! Never miss updates ab...
May 15, 2023•19 min
In May 2023, we attended IMMUNOLOGY2023, the annual meeting of the American Association of Immunologists in Washington, DC, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the third of five special episodes from the meeting. Highlights include Dr. Anthony Fauci’s talk on the COVID-19 pandemic response and Dr. Doug Green’s talk on T cell activation. Jason and Brenda discuss sessions on immune responses in aging and obesity, and making better cancer vaccines. Fe...
May 14, 2023•27 min
In May 2023, we attended IMMUNOLOGY2023, the annual meeting of the American Association of Immunologists in Washington, DC, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the second of five special episodes from the meeting. Brenda and Jason discuss sessions on peripheral neuroimmune interactions and tumor cellular therapy. Highlights include the President’s Address by Dr. Mark Davis and Dr. Barbara Rehermann’s presentation on wild mouse microbiota. Featured ...
May 13, 2023•31 min
In May 2023, we attended IMMUNOLOGY2023, the annual meeting of the American Association of Immunologists in Washington, DC, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the first of five special episodes from the meeting, in which Jason and Brenda summarize symposia on B and T-helper cells, and metabolic and gut microbiota. They discuss antigenic imprinting, lupus immunophenotyping and sex differences, dengue vaccines, and cytomegalovirus research. Featured...
May 12, 2023•24 min
Guest: Dr. Prasanna Jagannathan is an Assistant Professor of Medicine in Infectious Diseases and of Microbiology and Immunology at Stanford University. His research focuses on the mechanisms of clinical immunity to malaria. He talks about how repeated exposure to malaria can lead to tolerance without symptoms, promising vaccines and treatments to prevent reinfection, and the role of innate immune cells . He also discusses shifting from religious studies to teaching to medicine, and establishing ...
May 09, 2023•1 hr 9 min
Guest: Dr. Joshua Brody is the Director of the Lymphoma Immunotherapy Program at the Tisch Cancer Institute at Mount Sinai. The Brody lab studies basic and applied tumor immunology for the development of cancer immunotherapies, particularly for lymphomas and melanomas. He talks about dendritic cells to improve oncolytic virus immunotherapy and in situ vaccination to improve PD-1 blockade responses . Featured Products and Resources: IMMUNOLOGY2023 will be held May 11-15 in Washington, DC. Registe...
Apr 25, 2023•1 hr 4 min
Guest: Dr. Doug Green is the Peter C. Doherty Endowed Chair of Immunology at St. Jude Children’s Research Hospital. His research focuses on the central mechanisms of cell death, survival, and the immune response. He talks about what happens when cell death fails, the role of Myc, and setting up collaborations in science. Featured Products and Resources: Register for IMMUNOLOGY2023 Watch a Free Webinar on Best Practices and Innovative Technologies for T Cell Therapy Research. The Immunology Scien...
Apr 11, 2023•1 hr 13 min
Guests: Dr. Miriam Merad is the President & Scientific Programme Committee Co-Chair of the International Union of Immunological Societies (IUIS) and Dr. Mark Davis is the Scientific Programme Committee Chair. They talk about what to expect at the 2023 IUIS Congress being held November 27 – December 2 in Cape Town, South Africa. They discuss hosting the meeting in Africa, the importance of infectious disease research and international collaborations, and the highlights of this year’s program....
Mar 28, 2023•1 hr 7 min
Guest: Dr. Clovis Palmer is an Assistant Professor at Tulane University. He talks about how HIV hijacks metabolic processes and the role of HIF-1α in HIV infection . He also discusses using non-human primates to study SARS-CoV-2 and other viruses. Featured Products and Resources: IMMUNOLOGY2023 is taking place in Washington, DC from May 11-15th! Download free immunology wallcharts. The Immunology Science Round Up Bacterial Brain Invasion – Researchers identified a neuroimmune axis that exacerbat...
Mar 14, 2023•1 hr 3 min
Guests: Dr. Mark Davis is the President of the American Association of Immunologists, and Drs. Shruti Naik and Daniel Mucida are chairing Major Symposia at the upcoming IMMUNOLOGY2023 meeting in Washington, DC, May 11-15. They discuss what to expect at IMMUNOLOGY2023 and the highlights of this year’s program. Featured Products and Resources: Register for IMMUNOLOGY2023 by March 31 for a special discounted rate. Prepare for your next conference with this toolkit. The Immunology Science Round Up T...
Feb 28, 2023•1 hr 10 min
Guest: Dr. Hao Wu is the Asa and Patricia Springer Professor of Structural Biology at Harvard Medical School. Her lab focuses on the molecular and cellular mechanisms that govern the assembly, regulation, and therapeutic intervention of supramolecular complexes in innate immunity. She talks about cryo-electron microscopy and how her team used it to study the structures of the NLRP3 inflammasome disc , the B cell antigen receptor , and the Gasdermin D pore . She also discusses the role of AlphaFo...
Feb 14, 2023•1 hr 16 min
Guest: Dr. Caroline Sokol is a Principal Investigator at Massachusetts General Hospital and an Assistant Professor of Medicine at Harvard Medical School. Her lab studies the innate immune control of allergic disease. She talks about the role of sensory neurons and dendritic cells in allergic responses and insights into allergies from her son’s first bee sting. Featured Products and Resources: Register for IMMUNOLOGY2023! How to Isolate Tregs Using Easy 50 EasySep Magnet The Immunology Science Ro...
Jan 31, 2023•1 hr 13 min
Guests: In this special episode, Brenda and Jason chat with Drs. Daylon James and Arun Sharma, the hosts of the Stem Cell Podcast . Recorded in-person and led by Dr. Nicole Quinn from STEMCELL Technologies , the four hosts discuss the impact that podcasting has had on their careers and how it can make science and scientists more accessible. They also talk about the future of science communication and advice for young scientists pursuing careers in academia and industry. Featured Products and Res...
Jan 17, 2023•52 min
Guest: Dr. Miriam Merad is a Professor of Cancer Immunology and Director of the Marc and Jennifer Lipschultz Precision Immunology Institute at the Icahn School of Medicine at Mount Sinai. Her research focuses on dendritic cells and macrophages. She talks about tissue-resident macrophages in COVID-19 and cancer. She also discusses her new role as President of the International Union of Immunological Societies and bringing the international immunology community together at their upcoming meeting i...
Dec 20, 2022•1 hr 14 min
Guest: Dr. Jie Sun is the Harrison Professor of Medicine at the University of Virginia. His lab studies respiratory immunology under homeostasis and disease conditions. He talks about how long COVID compares to other post-viral conditions, and his lab’s work investigating mucosal immunity from mRNA vaccines . Featured Products and Resources: Abstract Submission Is Open for IMMUNOLOGY2023! Studying COVID-19 with Air-Liquid Interface Cultures The Immunology Science Round Up Cardiac Autoimmunity – ...
Dec 06, 2022•1 hr 14 min
Guest: Dr. Arthur Liesz is a Professor of Experimental Neurology at the University of Munich. The Liesz lab is interested in the interplay between the brain and the immune system after stroke. He talks about the inflammatory response to stroke, including T cell-modulated microglial activation. He also talks about stroke aftermath, including T cells that remain in the brain and the redistribution of function during recovery. Featured Products and Resources: Keep Current with the Latest in Neural ...
Nov 22, 2022•1 hr 18 min
Guest: Dr. Vijay Kuchroo is the Samuel L. Wasserstrom Professor of Neurology at Harvard Medical School. His major research interests include the role of co-stimulation in autoimmune diseases, as well as cell surface molecules and regulatory factors that regulate the induction of T cell tolerance and dysfunction. He talks about the conditions necessary to differentiate Th17 cells and their role in autoimmunity. He also discusses his group’s discovery of Tim-3, an inhibitor receptor on T cells whi...
Nov 08, 2022•1 hr 17 min
