Today’s very special episode comes from inside Kimbal Musk’s kitchen, where I get a hands-on look at his passion for cooking, community, and regenerative farming. Kimbal Musk is a South African restaurateur, chef, entrepreneur and a board member at Tesla Inc. and SpaceX, companies led by his brother, Elon Musk. Outside of the tech space, Kimbal is the force behind The Kitchen Restaurant Group and co-founder and chairman of Big Green, where he's pioneering outdoor classroom Learning Gardens...
Jan 16, 2024•1 hr 9 min•Ep. 1125
Today’s guest is not a scientist but a true visionary. Gary Vaynerchuk (aka Gary Vee), is a self-made entrepreneur and digital marketing pioneer. He started his business journey with a lemonade stand at age seven. Now, he’s a prolific content creator, best-selling author, and the co-founder of the massive digital agency VaynerMedia. What I love about Gary is that he leads with integrity, optimism, and, above all, gratitude. He’s a guy of wisdom, not just business—and that’s an important el...
Jan 11, 2024•58 min•Ep. 1124
I'm excited to welcome back Dr. Steven Gundry to The Human Upgrade for his sixth appearance, a tribute to his remarkable insights and ongoing research. Dr. Gundry, a true pioneer, is renowned for his books like "The Plant Paradox" and his groundbreaking work on lectins, changing how we understand our body's reaction to food. He's also a top cardiothoracic surgeon and a leader in robotic cardiac surgery, with over two decades of research into the microbiome, using diet and nutrition as key treatm...
Jan 09, 2024•1 hr 16 min•Ep. 1123
On today’s Upgrade Spotlight episode, we’re talking all about NAD+. In the biohacking world, everyone and their mother has heard of NMN and NAD+, but there’s more to it than meets the eye. To get into the nitty gritty of NAD+, we’re joined by Dr. Gregory Kelly, a naturopathic physician and the lead product formulator at Neurohacker Collective, also known as Qualia. I’m an advisor to the company, and they do fantastic and innovative work in the longevity space. Their NAD+ supplement is a qu...
Jan 05, 2024•41 min•Ep. 1122
Today, we take a look into the mindset and habits of successful entrepreneurs and mastering the art of organization for success, topics that today’s guest has totally mastered. Jesse Itzler has an impressive background with a bachelor's degree from American University and a further degree in justice, law, and society. His resume as an entrepreneur is also quite impressive, co-founding Marquis Jet, the world's largest private jet card company, which was later sold to Berkshire Hathaway/NetJ...
Jan 04, 2024•1 hr 26 min•Ep. 1121
Dr. Anthony Youn, aka “America’s Holistic Plastic Surgeon,” is an expert in your face. He joins us to answer some burning questions… Can plastic surgery actually be holistic? Can you turn back the clock without going under the knife? And… What work should I get done to my face? Today, we’re talking all about how to hack your face and save your skin. Dr. Youn is a nationally-recognized, board-certified plastic surgeon. He’s the most followed plastic surgeon on social media and a TikTok star...
Jan 02, 2024•1 hr 1 min•Ep. 1120
Get ready for this important download on a fascinating biohacking compound you haven’t heard me talk about before: Urolithin A. It’s a postbiotic that supports the mitochondria, and it’s backed by impressive studies on longevity, anti-cancer effects, cognitive function, and muscle strength. In fact, this compound has earned a place in my permanent stack—which you know isn’t easy to pull off. Today, I chat with Dr. Dominic Denk, who’s done some of the original research on Urolithin A and the comp...
Dec 28, 2023•59 min•Ep. 1119
In this special end-of-year "best of" episode, you'll learn the Top 10 hallmarks of aging, the role of functional medicine in restoring and reversing aging, and the many practical ways you can promote your own longevity. Mark Hyman, M.D., joins Dave in Austin to talk all things longevity. Driven by his desire for a healthier, longer life for himself and others, Dr. Mark immersed himself in the latest scientific research on aging and longevity. Through his findings, he realized that the body has ...
Dec 26, 2023•1 hr 8 min•Ep. 1118
In this episode of The Human Upgrade you’ll meet Robert Waldinger, M.D., who leads an extraordinary scientific study on happiness that’s still going strong after eight decades. The study set out to understand human health by what made people thrive . Since 1938, the Harvard Study of Adult Development has tracked two groups of men and their families with the goal of discovering what really makes for a good life. Along the way, thousands of questions were asked, and hundreds of measurem...
Dec 21, 2023•1 hr 14 min•Ep. 1117
This episode is a deep dive into the heart of modern fitness, led by one of its most influential figures. Joining me today is Lavinia Errico, the visionary co-founder of Equinox Fitness Clubs. Lavinia isn't just a pioneer in the fitness industry, she's a passionate advocate for a life that's healthier, more fulfilled, balanced, and brimming with joy. She's dedicated to helping others achieve these same goals, inspiring people to delve into self-awareness and embrace transformative journeys...
Dec 19, 2023•1 hr 4 min•Ep. 1116
Today is a long-awaited show with none other than Bryan Johnson, an entrepreneur, venture capitalist, author, and professional rejuvenation athlete on a mission to discover the next evolution of humankind. While Bryan is well known in the longevity space, I’ve been a fan of his work for years because of his neuroscience background. Bryan started a company called Kernel, which makes devices that monitor and record brain activity. Kernel uses what I would call the most comprehensive way of l...
Dec 14, 2023•1 hr 27 min•Ep. 1115
Coming to you live from Austin, Texas, I can’t wait for you to meet Dan Freed—a man who’s journeyed from the hot kitchen of high-end cooking to the frontier of brain improvement. Dan’s the founder and CEO of Thesis, a company that's revolutionizing the way we think about our brain's potential, and his journey is one of resilience and innovation. Picture this… A kid struggling with focus throughout childhood, he drops out of high school and claws his way up in the ruthless restaurant indust...
Dec 12, 2023•1 hr 12 min•Ep. 1114
Cynthia Thurlow joins the show to talk about how intermittent fasting can help women change their body, metabolic system and brain function. She has tips for women at all stages: from active menstrual cycles to perimenopause to menopause. Cynthia is a Johns Hopkins-trained nurse practitioner and functional nutritionist founded and serves as CEO of Everyday Wellness Project. She holds a Master of Science degree in Nursing and Functional Nutrition certifications with advanced trainings in En...
Dec 07, 2023•1 hr 6 min
Dive into a captivating exploration of human biology and connection—erotic blueprints. Discover four primal drivers: fear, food, friends, and fertility, with a unique focus on fertility in this episode. Miss Jaiya, a leader in somatic sexology, sheds light on the intimate realm of human relationships and pleasure. As an award-winning somatic sexologist and creator of The Erotic Blueprints® Framework, Jaiya dedicates her expertise to helping people understand their unique erotic blueprints and th...
Dec 05, 2023•1 hr 24 min•Ep. 1112
I am excited to chat with a longtime friend who is a fellow expert in how to make your brain work better. Jim Kwik is an absolute wizard when it comes to maximizing your brain's potential. We go way back, over a decade, and I can vouch for his incredible expertise in the realm of cognitive enhancement. He also has just released an expanded addition to his best-selling book, Limitless, where he delves deep into topics that both he and I hold near and dear—nootropics and brain enhancement. J...
Nov 30, 2023•1 hr 11 min•Ep. 1111
Today’s guest is nothing short of a modern-day Willy Wonka for Generation X. He built a billion-dollar ecstasy business in the '90s and did not end up behind bars. That's a story you've got to hear. Our guest today, Shaahin Cheyene, not only dabbled in the wild world of herbal ecstasy but also managed to stay out of trouble despite being investigated by seven attorney generals. And get this, he wasn't even 18 when he pulled off these daring feats. Shaahin's story doesn't stop there. Since those ...
Nov 28, 2023•1 hr 9 min•Ep. 1110
I’ve been eagerly looking forward to this conversation with a dear friend and a true luminary in the realm of relationships and personal development, John Gray. for quite some time. You probably recognize his name as the author of the famous book, Men Are From Mars, Women Are From Venus. But what's especially exciting is how John has evolved his insights to address the changing dynamics between men and women in the modern world, as he highlighted in his 2020 book, Beyond Mars and Venus: Re...
Nov 21, 2023•2 hr 45 min•Ep. 1109
Today's episode delves deeper into the captivating world of quantum field therapy and the power of intention, featuring the renowned Lynne McTaggart. Lynne, known for her books "The Power of Eight," and “The Field” offers groundbreaking insights into the profound impact of group intention. The discussion unravels the significance of the number 8, explores the mechanics behind Lynne's intention experiments, and examines the profound effects of healing and connection on our being. The conversation...
Nov 16, 2023•1 hr 25 min•Ep. 1108
How about we have a conversation with one of the most spiritually influential living people on earth? Yes, you heard that right! Today's guest was bestowed with this honor by Watkins MindBodySpirit, and if that's not impressive enough, AgeNation awarded him a Life Achievement Award. Today, we have the incredible privilege of sitting down with a true luminary in the world of spirituality, health, and resilience. His name is Mark Nepo, and he's not just an authority on spiritual matters and ...
Nov 14, 2023•1 hr 10 min•Ep. 1107
Today, we delve deep into the world of cybernetics and the potential cyberpunk future with a true pioneer and a living legend in the field, Kevin Warwick. As an Emeritus professor at Coventry and Reading Universities, Kevin is celebrated as the world's first cyborg, earning him the moniker: Captain Cyborg. In this episode, we explore the incredible journey of Kevin Warwick, who became a cyborg over 25 years ago by implanting a chip in his arm, the size of a coin, enabling him to interact with th...
Nov 09, 2023•1 hr 8 min•Ep. 1106
Today, we talk about one of my favorite biohacking topics: hormones. Starting way back before I first had kids, I’ve studied hormones as they relate to fertility – leading to the first of just a few books over the years, The Better Baby Book. And it's been an area of passion ever since because hormones also control your mood and your energy levels and your happiness. So I wanted to invite Dr. Francesca LeBlanc on the show – someone who has a very interesting blend of being a board certified chir...
Nov 07, 2023•1 hr 8 min•Ep. 1105
Today, let's delve into a topic often overlooked but crucial for our overall health: our skin. Over the past decade, I've started seeing our skin as more than just a protective layer; it's a major organ, just like our liver or heart. Its health goes beyond appearances – it profoundly influences our biology and well-being. Today, I welcome Carolina Reis Oliveira, the founder of OneSkin, a skin health company, to the show. She'll share exciting insights from recent research on specific peptides th...
Nov 03, 2023•57 min•Ep. 1104
In this episode of The Human Upgrade my guest fits right into the podcast transition to The Human Upgrade because he gets into the grittiness of what humans can do to level themselves up. No. 1 New York Times bestselling author Robert Greene shares science-backed knowledge about human nature. You know you want to be more powerful, more in control and excellent at what you do. Robert’s insights help you do just that. He gives you actionable tips that help you unlock limitations you ma...
Nov 02, 2023•1 hr 23 min•Ep. 1103
Let’s explore the mind-bending subject of quantum biology with Dr. Catherine Clinton, a licensed naturopathic physician with a focus on gut health, autoimmunity and psychoneuroimmunology. A respected author, speaker, health advocate, Dr. Clinton has been on the front lines of health and wellness for over 15 years, helping people overcome the very health challenges I once grappled with in my younger years – issues like autoimmune conditions and Lyme disease, which we now understand are often inte...
Oct 31, 2023•1 hr 4 min•Ep. 1102
Remember the days when we believed in one-size-fits-all diets? Well, thankfully those days are behind us. Today's episode is all about the crucial shift towards personalized nutrition. Our guests, Matt Gallant and Wade Lightheart from BiOptimizers, are no strangers to the show. They're also the authors of The Ultimate Nutrition Bible, a monumental resource that unlocks the secrets of crafting a diet tailored precisely to your genetics, goals, and lifestyle. We delve into the art and scienc...
Oct 26, 2023•1 hr 12 min•Ep. 1101
About ten years ago, I began working colostrum into my product development efforts – seeing its game changing nutritional value for exactly what it was, well before the mainstream sank its teeth into it. Today’s guest has the experience and intellect to take us deep into the science behind it. Dr. Sarah Rahal, MD – the brainchild of ARMRA – is a double board-certified pediatric neurologist with expertise in environmental and functional medicine. After years of clinical work and research, she was...
Oct 24, 2023•1 hr 9 min•Ep. 1100
Friends, it is my great pleasure to introduce Vani Hari, aka Food Babe, someone I've had the privilege of knowing for nearly a decade. She is a relentless advocate for clean, safe, and wholesome food. She has dedicated herself to a tireless campaign aimed at eliminating harmful ingredients from our food supply, particularly in the United States, where food standards can sometimes be shockingly low. Her efforts have been resolute in challenging major food corporations when their practices a...
Oct 20, 2023•1 hr 2 min•Ep. 1099
In this episode, we're broadcasting live from Toronto with Dr. Adeel Khan, a leading figure in the field of gene and cell therapies. Dr. Adeel Khan, who holds an M.D. and is a Canadian Board Certified Physician, specializes in regenerative and cellular medicine. He is also a recognized authority as a key opinion leader for The American College of Regenerative Medicine, the foremost advocate for best practices in North America. Notably, he co-founded Xalt, a fitness-technology company, and ...
Oct 18, 2023•2 hr 51 min•Ep. 1098
Today, we cover something that everybody wants at some level or another—muscle. If you want to live a long time and you've fallen for the plant based nonsense science that's out there to sell more Froot Loops, well, you're heading in the wrong direction from a longevity perspective. The cold, hard truth is that skeletal muscle mass drives longevity. Dr. Gabrielle Lyon joins the show today to flex her own intellectual muscles on protein intake, reframing the hallmarks of aging, supplementing amin...
Oct 17, 2023•1 hr 5 min•Ep. 1097
In this episode of The Human Upgrade - anesthetist and researcher, Mark Harper, M.D., Ph.D., shares how the power of cold-water practices can treat depression, anxiety, PTSD, arthritis, migraines and other health conditions you may be experiencing. Despite all the attention cold water swimming and immersion has gotten in recent years—thank you, Wim Hof—the scientific community hasn’t taken it very seriously. That’s changing now. Dr. Harper’s research goes beyond what we already know about the be...
Oct 12, 2023•50 min•Ep. 1096
