Unique Safety Issues Associated With Virus-vectored Vaccines: Potential For Theoretical Consequences of Recombination with Wild Type Virus Strains

SHR # 2594 :: Unique Safety Issues Associated With Virus-vectored Vaccines: Potential For Theoretical Consequences of Recombination with Wild Type Virus Strains - Keith Bell - The COVID-19 vaccine will be a virus-vector vaccine. In 2003 and 2013, the World Health Organization convened informal consultations on characterization and quality aspects of vaccines based on live virus vectors. In the resulting reports, one of several issues raised for future study was the potential for recombination of virus-vectored vaccines with wild type pathogenic virus strains. Our discussion today assesses this issue formulated by the Brighton Collaboration. Study Discussed On Today's Show https://www.sciencedirect.com/science/article/pii/S0264410X16302250?fbclid=IwAR1gsVw1VoikQyfbdHk4qfB8cSSeWbFi44WvSevNqni6ioHqPldb6hWXUxg