We talk to Dr Vijay Yadav about some of the results in terms of lifespan and healthspan from the recent paper that he was the main author on. Dr Yadav leads the Systems Biology of Aging Laboratory, which aims to identify novel functional connections between organs and to unravel factors that underlie human metabolism and its disorders. The lab's expertise is in the development of a variety of technologies including mouse genetic (CRISPR/Cas, homologous recombination in embryonic stem cells, iPS ...
Aug 20, 2023•19 min•Season 34Ep. 2
We talk to Dr Vijay Yadav about taurine, why he started studying it, some of the history and how it varies with age. Dr Yadav leads the Systems Biology of Aging Laboratory, which aims to identify novel functional connections between organs and to unravel factors that underlie human metabolism and its disorders. The lab's expertise is in the development of a variety of technologies including mouse genetic (CRISPR/Cas, homologous recombination in embryonic stem cells, iPS cells), genomic (Nucleic ...
Aug 16, 2023•11 min•Season 34Ep. 1
In this episode Dr Yurth talks about her longevity protocol, including her use of a CGM and protein requirements. Dr Elizabeth Yurth is Co-Founder and Chief Medical Officer of Boulder Longevity Institute. Along with her 30 years as a practicing orthopedist specializing in sports medicine, Dr. Yurth has made it her mission to share the latest scientific research on how to truly heal the body at the cellular level. 🌐 Boulder Longevity Institute https://boulderlongevity.com/ 🌐 Human Optimization ...
Aug 15, 2023•13 min•Season 32Ep. 4
In this video Dr Yurth introduces spermidine as an autophagy activator and talks about the regimen she uses while focusing on muscle maintenance and growth. Dr Elizabeth Yurth is Co-Founder and Chief Medical Officer of Boulder Longevity Institute. Along with her 30 years as a practicing orthopedist specializing in sports medicine, Dr. Yurth has made it her mission to share the latest scientific research on how to truly heal the body at the cellular level. 🌐 Boulder Longevity Institute https://b...
Aug 13, 2023•10 min•Season 32Ep. 3
In this video Dr Yurth introduces what peptides are and talks about some of the most important ones for longevity and how they work. Dr Elizabeth Yurth is Co-Founder and Chief Medical Officer of Boulder Longevity Institute. Along with her 30 years as a practicing orthopedist specializing in sports medicine, Dr. Yurth has made it her mission to share the latest scientific research on how to truly heal the body at the cellular level. 🌐 Boulder Longevity Institute https://boulderlongevity.com/ 🌐 ...
Aug 10, 2023•27 min•Season 33Ep. 2
In this episode Dr Yurth talks about why she set up the Boulder Longevity Institute and the key metrics that she looks for to determine a persons true health Dr Elizabeth Yurth is Co-Founder and Chief Medical Officer of Boulder Longevity Institute. Along with her 30 years as a practicing orthopedist specializing in sports medicine, Dr. Yurth has made it her mission to share the latest scientific research on how to truly heal the body at the cellular level. 🌐 Boulder Longevity Institute https://...
Aug 08, 2023•14 min•Season 33Ep. 1
In this episode Dr Newport talks about some of the do's and don'ts to minimize the risk of getting Alzheimer's. In this video Dr Bohr discusses his experience with NR, NMN and Urolithin A, using NAD boosters in people and the importance of measuring not only NAD but also its metabolites. And the impact of NR supplementation on the gut microbiome. Dr. Vilhelm Bohr is a molecular biologist who is currently an affiliate professor at the University of Copenhagen. He is also a former chief of the Lab...
Aug 05, 2023•14 min•Season 32Ep. 4
In this episode Dr Bohr talks about NR's impact on age related loss of hearing and smell in mice Dr. Vilhelm Bohr is a molecular biologist who is currently an affiliate professor at the University of Copenhagen. He is also a former chief of the Laboratory of Molecular Genetics at the National Institute on Aging (NIA). Dr. Bohr's research interests focus on DNA repair, mitochondrial biology, and energy metabolism. He is particularly interested in how these processes interact with one another to i...
Aug 03, 2023•13 min•Season 32Ep. 3
In this episode Dr Bohr talks about his work with Alzheimer's using Nicotinamide Riboside (NR) and how this impacts DNA repair, mitophagy, senescence and inflammation. Dr. Vilhelm Bohr is a molecular biologist who is currently an affiliate professor at the University of Copenhagen. He is also a former chief of the Laboratory of Molecular Genetics at the National Institute on Aging (NIA). Dr. Bohr's research interests focus on DNA repair, mitochondrial biology, and energy metabolism. He is partic...
Aug 01, 2023•23 min•Season 32Ep. 2
In this episode Dr Bohr talks about mitochondria, how they change with age and the importance of mitophagy. Dr. Vilhelm Bohr is a molecular biologist who is currently an affiliate professor at the University of Copenhagen. He is also a former chief of the Laboratory of Molecular Genetics at the National Institute on Aging (NIA). Dr. Bohr's research interests focus on DNA repair, mitochondrial biology, and energy metabolism. He is particularly interested in how these processes interact with one a...
Jul 30, 2023•12 min•Season 32Ep. 1
In this video Dr Newport talks about some of the trials which are using MCT and ketogenic diets to address mild cognitive impairment and Parkinson's. Dr Newport's web page https://coconutketones.com/ Mary T. Newport, M.D. became a messenger in 2008 when she found a nutritional intervention that supplied ketones as alternative fuel for the brain for her husband Steve Newport with early-onset Alzheimer’s disease. Steve responded dramatically to consuming medium-chain triglycerides (MCTs) from coco...
Jul 27, 2023•10 min•Season 31Ep. 6
Hi All, my sincere apologies for the repeat posting of episode 4 as episode 5. I have now deleted that version. This the correct version but has an advert in it that is intended for the video edition only. At this point is difficult to remove the advert. In this video Dr Newport talks about some supplements to take and some to be careful about. And also the benefits seen with ketone esters and ketone salts in clinical trials. Dr Newport's web page https://coconutketones.com/ Mary T. Newport, M.D...
Jul 26, 2023•18 min•Season 31Ep. 5
In this episode Dr Newport talks about some of the do's and don'ts to minimize the risk of getting Alzheimer's. Dr Newport's web page https://coconutketones.com/ Mary T. Newport, M.D. became a messenger in 2008 when she found a nutritional intervention that supplied ketones as alternative fuel for the brain for her husband Steve Newport with early-onset Alzheimer’s disease. Steve responded dramatically to consuming medium-chain triglycerides (MCTs) from coconut oil which produce ketones when con...
Jul 23, 2023•12 min•Season 31Ep. 4
Our brain needs fuel all the time, including when we sleep. In the case it is insulin resistant there need to be ketones always available. In this video Dr Newport talks about how to maintain ketones in your blood and some of the benefits of a low carbohydrate diet. Dr Newport's web page https://coconutketones.com/ Mary T. Newport, M.D. became a messenger in 2008 when she found a nutritional intervention that supplied ketones as alternative fuel for the brain for her husband Steve Newport with e...
Jul 20, 2023•10 min•Season 31Ep. 3
In this video Dr Newport talks about why she uses both MCT as well as coconut and the advantages of lauric acid (C:12) one of the main constituents of coconut oil. Dr Newport's web page https://coconutketones.com/ Mary T. Newport, M.D. became a messenger in 2008 when she found a nutritional intervention that supplied ketones as alternative fuel for the brain for her husband Steve Newport with early-onset Alzheimer’s disease. Steve responded dramatically to consuming medium-chain triglycerides (M...
Jul 18, 2023•12 min•Season 31Ep. 2
In this video Dr Newport tells the story of her husband's experience with Alzheimer's and how a ketogenic diet supplemented with coconut and MCT oil improved his condition. Dr Newport's web page https://coconutketones.com/ Mary T. Newport, M.D. became a messenger in 2008 when she found a nutritional intervention that supplied ketones as alternative fuel for the brain for her husband Steve Newport with early-onset Alzheimer’s disease. Steve responded dramatically to consuming medium-chain triglyc...
Jul 15, 2023•29 min•Season 31Ep. 1
In this video Dr Kaufmann about her thinking on supplements, as well as looking at COVID, autoimmune diseases, eye aging. We also discuss some other therapies, including stem cells, exosomes, DNA infusion and plasmapheresis. Sandra Kaufmann, is a cell biologist who for the last seven years has been the Chief of Pediatric Anesthesia at the Joe DiMaggio Children’s Hospital. She is also the founder of the Kaufmann Antiaging Institute and the author of two books, The Kaufmann Protocol: Why We Age an...
Jul 13, 2023•21 min•Season 30Ep. 4
In this video Dr Kaufmann talks about preserving the skin, a very important topic for her as she is a rock climber and spends a fair amount of time outside at high altitudes! Sandra Kaufmann, is a cell biologist who for the last seven years has been the Chief of Pediatric Anesthesia at the Joe DiMaggio Children’s Hospital. She is also the founder of the Kaufmann Antiaging Institute and the author of two books, The Kaufmann Protocol: Why We Age and How to Stop It and her new book, The Kaufmann Pr...
Jul 11, 2023•11 min•Season 30Ep. 3
In this video Dr Kaufmann introduces talks about mitochondria and keeping them healthy and also maintaining muscle. We also touch on blood glucose levels and natural SGL2 inhibitors. Sandra Kaufmann, is a cell biologist who for the last seven years has been the Chief of Pediatric Anesthesia at the Joe DiMaggio Children’s Hospital. She is also the founder of the Kaufmann Antiaging Institute and the author of two books, The Kaufmann Protocol: Why We Age and How to Stop It and her new book, The Kau...
Jul 09, 2023•14 min•Season 30Ep. 2
In this video Dr Kaufmann introduces the Kaufmann Protocol and the method behind how she constructed it. She also talks about the rating system for that she uses for the supplements. Sandra Kaufmann, is a cell biologist who for the last seven years has been the Chief of Pediatric Anesthesia at the Joe DiMaggio Children’s Hospital. She is also the founder of the Kaufmann Antiaging Institute and the author of two books, The Kaufmann Protocol: Why We Age and How to Stop It and her new book, The Kau...
Jul 06, 2023•14 min•Season 30Ep. 1
In this video Dr Harris talks about how omega-3's impact eye and brain health. He also talks about the Fatty Acid Research Institute that he set up and the work they are doing. Dr. Bill Harris has been a leading researcher in the omega-3 fatty acid field for 40 years. He has over 300 scientific papers on fatty acids and health, the vast majority on omega-3. He has been on the faculty of three medical schools (Universities of Kansas, Missouri (at Kansas City), and South Dakota), and has received ...
Jul 04, 2023•14 min•Season 29Ep. 5
In this video Dr Harris talks about his recent review paper looking a the omega-3 index and all cause mortality and the omega-3's impact on heart health. Dr. Bill Harris has been a leading researcher in the omega-3 fatty acid field for 40 years. He has over 300 scientific papers on fatty acids and health, the vast majority on omega-3. He has been on the faculty of three medical schools (Universities of Kansas, Missouri (at Kansas City), and South Dakota), and has received 5 NIH grants to study o...
Jul 02, 2023•12 min•Season 29Ep. 4
In this episode Dr Harris talks about where to get omega-3 from in your diet. Also supplements, how much and when to take. He also introduces the omega-3 index calculator. Dr. Bill Harris has been a leading researcher in the omega-3 fatty acid field for 40 years. He has over 300 scientific papers on fatty acids and health, the vast majority on omega-3. He has been on the faculty of three medical schools (Universities of Kansas, Missouri (at Kansas City), and South Dakota), and has received 5 NIH...
Jun 28, 2023•18 min•Season 29Ep. 3
In this video Dr Harris talks about the omega-3 introduces the omega-3 index and explains what it is. We also talk about its impact on RDW, red blood cell distribution width, which is a component of the PhenoAge calculation Dr. Bill Harris has been a leading researcher in the omega-3 fatty acid field for 40 years. He has over 300 scientific papers on fatty acids and health, the vast majority on omega-3. He has been on the faculty of three medical schools (Universities of Kansas, Missouri (at Kan...
Jun 24, 2023•8 min•Season 29Ep. 2
In this video Dr Harris introduces the various types of fats and then goes into more detail on essential omega-3 fatty acids. He also discusses omega-6 fatty acids and whether they are positive for health or not. Dr. Bill Harris has been a leading researcher in the omega-3 fatty acid field for 40 years. He has over 300 scientific papers on fatty acids and health, the vast majority on omega-3. He has been on the faculty of three medical schools (Universities of Kansas, Missouri (at Kansas City), ...
Jun 18, 2023•12 min•Season 29Ep. 1
In this video Professor Zemel discusses what he sees as the most promising areas of investigation in healthspan as well as his own health protocol. COSMOS Trial web page https://cosmostrial.org/ Dr Michael Zemel is Professor Emeritus at the University of Tennessee and the founder and chief scientific officer at NuSirt, a company developing solutions to treat chronic diseases of aging and over nutrition. In his 40 years of academic research he has authored more than 200 peer reviewed publications...
Jun 11, 2023•17 min•Season 29Ep. 4
In this video Professor Zemel discusses OS200 the regulated therapy that NuSirt is currently in human trials with for obesity, NAFLD and pre-diabetes. The therapy includes leucine, metformin and sildenafil. Dr Michael Zemel is Professor Emeritus at the University of Tennessee and the founder and chief scientific officer at NuSirt, a company developing solutions to treat chronic diseases of aging and over nutrition. In his 40 years of academic research he has authored more than 200 peer reviewed ...
Jun 08, 2023•14 min•Season 29Ep. 3
In this video Professor Zemel discusses human trials of leucine with B6 and why they tested that combination. These human trials then led to trials in companion dogs, which is a strange twist. And finally he shares his thoughts on the nutraceutical market. Dr Michael Zemel is Professor Emeritus at the University of Tennessee and the founder and chief scientific officer at NuSirt, a company developing solutions to treat chronic diseases of aging and over nutrition. In his 40 years of academic res...
Jun 03, 2023•14 min•Season 29Ep. 2
In this video Professor Zemel introduces his research on leucine and why it is so special. He then talks about how it helps to amplify the effects of resveratrol and NAD precursors. Dr Michael Zemel is Professor Emeritus at the University of Tennessee and the founder and chief scientific officer at NuSirt, a company developing solutions to treat chronic diseases of aging and over nutrition. In his 40 years of academic research he has authored more than 200 peer reviewed publications. 🌐NuSirt Bi...
May 27, 2023•24 min•Season 28Ep. 1
In this video Dr Guttuso talks about his experience with lithium and long COVID and the clinical trial that he has started to study this further. He also shares his personal health protocol. Thomas Guttuso, Jr., MD, is a professor of neurology at the University at Buffalo. He has been treating patients with Parkinson’s for over twenty years and has published over thirty articles in leading medical journals. Dr Guttuso recently published the book “The Promise Of Lithium” on the use of lithium sup...
May 20, 2023•18 min•Season 27Ep. 4
