In this video Dr Guttuso talks using lithium as a supplement and the different formulations (carbonate, orotate and aspartate), the dosage, safety profile and possible interaction with other medications. Thomas Guttuso, Jr., MD, is a professor of neurology at the University at Buffalo. He has been treating patients with Parkinson’s for over twenty years and has published over thirty articles in leading medical journals. Dr Guttuso recently published the book “The Promise Of Lithium” on the use o...
May 15, 2023•10 min•Season 28Ep. 3
In this episode Dr Guttuso talks about two positive random controlled clinical trials of low dose lithium with Alzheimer's and two on going trials. Thomas Guttuso, Jr., MD, is a professor of neurology at the University at Buffalo. He has been treating patients with Parkinson’s for over twenty years and has published over thirty articles in leading medical journals. Dr Guttuso recently published the book “The Promise Of Lithium” on the use of lithium supplementation to potentially slow the progre...
May 11, 2023•20 min•Season 27Ep. 2
In this episode Dr Guttuso shares some of his background, how he identified lithium as a potential supplement to slow or prevent Alzheimer's and Parkinson's and the observational data supporting this. Thomas Guttuso, Jr., MD, is a professor of neurology at the University at Buffalo. He has been treating patients with Parkinson’s for over twenty years and has published over thirty articles in leading medical journals. Dr Guttuso recently published the book “The Promise Of Lithium” on the use of l...
May 07, 2023•16 min•Season 27Ep. 1
In this episode Professor Sebastiano discusses the future for partial reprogramming and other longevity technologies that he sees as the most promising. Professor Vittorio Sebastiano manages a lab in Stanford University which developed and patented technology for partial cellular reprogramming. He co-founded Turn Bio, where he is now Head of research, to translate this technology into clinical applications. And with that, let me start the interview. Turn Bio website https://www.turn.bio/ Profess...
Apr 29, 2023•7 min•Season 26Ep. 6
In this video Professor Sebastiano discusses how the timing of the therapy might work, concerns of whether the "point of no return" might be crossed and what aspects of aging are not covered by partial cellular reprogramming. Professor Vittorio Sebastiano manages a lab in Stanford University which developed and patented technology for partial cellular reprogramming. He co-founded Turn Bio, where he is now Head of research, to translate this technology into clinical applications. And with that, l...
Apr 23, 2023•11 min•Season 26Ep. 5
In this episode Professor Sebastiano discusses the three most advanced interventions that Turn Bio is working on, for skin, immunology and muscles and when they will be available for human trial. Professor Vittorio Sebastiano manages a lab in Stanford University which developed and patented technology for partial cellular reprogramming. He co-founded Turn Bio, where he is now Head of research, to translate this technology into clinical applications. And with that, let me start the interview. Tur...
Apr 21, 2023•10 min•Season 26Ep. 4
In this episode Professor Sebastiano discusses the results that he and his team have had in rejuvenating human cells and how the process could be applied as well as their experience rejuvenating a muscle in an old mouse. Professor Vittorio Sebastiano manages a lab in Stanford University which developed and patented technology for partial cellular reprogramming. He co-founded Turn Bio, where he is now Head of research, to translate this technology into clinical applications. And with that, let me...
Apr 16, 2023•10 min•Season 26Ep. 4
In this episode Professor Sebastiano discusses the results that he and his team have had in rejuvenating human cells and how the process could be applied as well as their experience rejuvenating a muscle in an old mouse. Professor Vittorio Sebastiano manages a lab in Stanford University which developed and patented technology for partial cellular reprogramming. He co-founded Turn Bio, where he is now Head of research, to translate this technology into clinical applications. And with that, let me...
Apr 12, 2023•9 min•Season 26Ep. 3
In this video Professor Sebastiano discusses how the mRNA is delivered to the specific cells and how the recent explosion of mRNA interest has changed the development landscape. Professor Vittorio Sebastiano manages a lab in Stanford University which developed and patented technology for partial cellular reprogramming. He co-founded Turn Bio, where he is now Head of research, to translate this technology into clinical applications. And with that, let me start the interview. Turn Bio website http...
Apr 08, 2023•9 min•Season 26Ep. 2
In this episode Professor Sebastiano introduces ERA, Epigenetic Reprogramming of Age technology and talks about his thoughts on some of the causes of aging Professor Vittorio Sebastiano manages a lab in Stanford University which developed and patented technology for partial cellular reprogramming. He co-founded Turn Bio, where he is now Head of research, to translate this technology into clinical applications. And with that, let me start the interview. Turn Bio website https://www.turn.bio/ Prof...
Apr 02, 2023•13 min•Season 26Ep. 1
In this episode Dr Newman talks about ketones as a fuel for the brain and how this becomes more important as we age and the brain can become less able to use glucose. Dr John Newman is a professor at the Buck Institute and at University of California, San Francisco. He hopes to translate what we are learning of the pathways that control aging into therapies to improve the health and independence of older adults. His research at the Buck studies the molecular details of how diet regulate the path...
Mar 29, 2023•8 min•Season 25Ep. 5
In this episode Dr Newman talks the ITP lifespan trials that used butanediol but did not see a significant result. He covers what might have caused this and some of the chemistry behind butanediol and butyrate. Dr John Newman is a professor at the Buck Institute and at University of California, San Francisco. He hopes to translate what we are learning of the pathways that control aging into therapies to improve the health and independence of older adults. His research at the Buck studies the mol...
Mar 26, 2023•8 min•Season 25Ep. 4
In this episode Dr Newman talks ways of boosting ketones through ketone supplements, what the different types are and what has been seen with them in human trials. Dr John Newman is a professor at the Buck Institute and at University of California, San Francisco. He hopes to translate what we are learning of the pathways that control aging into therapies to improve the health and independence of older adults. His research at the Buck studies the molecular details of how diet regulate the pathway...
Mar 22, 2023•11 min•Season 25Ep. 3
In this episode Dr Newman talks about experiments that he and other teams have run on mice lifespan and healthspan while they were on ketogenic diets. Dr John Newman is a professor at the Buck Institute and at University of California, San Francisco. He hopes to translate what we are learning of the pathways that control aging into therapies to improve the health and independence of older adults. His research at the Buck studies the molecular details of how diet regulate the pathways that contro...
Mar 19, 2023•9 min•Season 25Ep. 2
In this episode Dr Newman discusses ketones and their impact on aging. Dr John Newman is a professor at the Buck Institute and at University of California, San Francisco. He hopes to translate what we are learning of the pathways that control aging into therapies to improve the health and independence of older adults. His research at the Buck studies the molecular details of how diet regulate the pathways that control aging, with a focus on ketone bodies. Dr Newman's lab at the Buck Institute ht...
Mar 15, 2023•12 min•Season 25Ep. 1
In this episode Dr Davidsohn discusses the next generation therapies that Rejuvenate Bio are working on. We also discuss, klotho, RJB02 and his personal protocol. Dr Noah Davidsohn is a founder and Chief Scientific Officer of Rejuvenate Bio a company developing gene therapies to treat aging and age related diseases. Rejuvenate Bio website https://www.rejuvenatebio.com/ Dr Davidsohn's paper mentioned in the interview A single combination gene therapy treats multiple age-related diseases https://p...
Mar 08, 2023•11 min•Season 23Ep. 5
In this episode Dr Davidsohn discusses taking RJB01 to trial with humans for a rare heart disease and how gene therapy is viewed by the FDA. Dr Noah Davidsohn is a founder and Chief Scientific Officer of Rejuvenate Bio a company developing gene therapies to treat aging and age related diseases. Rejuvenate Bio website https://www.rejuvenatebio.com/ Dr Davidsohn's paper mentioned in the interview A single combination gene therapy treats multiple age-related diseases https://pubmed.ncbi.nlm.nih.gov...
Mar 04, 2023•9 min•Season 23Ep. 4
In this episode Dr Davidsohn discusses how the gene therapy helps with heart health and is only required one time. Dr Noah Davidsohn is a founder and Chief Scientific Officer of Rejuvenate Bio a company developing gene therapies to treat aging and age related diseases. Rejuvenate Bio website https://www.rejuvenatebio.com/ Dr Davidsohn's paper mentioned in the interview A single combination gene therapy treats multiple age-related diseases https://pubmed.ncbi.nlm.nih.gov/31685628/ NOVOS Core &...
Mar 01, 2023•9 min•Season 23Ep. 3
In this episode Dr Davidsohn talks about the first therapy Rejuvenate Bio is working on which restores a more youthful protein expression in the liver which then impacts the rest of the body. Dr Noah Davidsohn is a founder and Chief Scientific Officer of Rejuvenate Bio a company developing gene therapies to treat aging and age related diseases. Rejuvenate Bio website https://www.rejuvenatebio.com/ Dr Davidsohn's paper mentioned in the interview A single combination gene therapy treats multiple a...
Feb 26, 2023•9 min•Season 23Ep. 2
In this episode we discuss some of Dr Davidsohn's background, the mission of Rejuvenate Bio and the gene therapy that was developed at Dr Church's lab and is now being used to treat companion dogs. Dr Noah Davidsohn is a founder and Chief Scientific Officer of Rejuvenate Bio a company developing gene therapies to treat aging and age related diseases. Rejuvenate Bio website https://www.rejuvenatebio.com/ Dr Davidsohn's paper mentioned in the interview A single combination gene therapy treats mult...
Feb 19, 2023•8 min•Season 23Ep. 1
In this episode Dr Verburgh talks about his personal longevity protocol. Nutrigerontology: why we need a new scientific discipline to develop diets and guidelines to reduce the risk of aging-related diseases And is available here: https://pubmed.ncbi.nlm.nih.gov/25470422/ Dr Kris Verburgh is a medical doctor and researcher at the Free University of Brussels where his focus is the aging process, metabolism and nutrition. He published his first book when he was 16 and his latest is the Longevity C...
Feb 05, 2023•6 min•Season 22Ep. 9
In this episode Dr Verburgh talks about his theory of aging and why he thinks that epigenetic dysregulation is the most fundamental of the hall marks. Nutrigerontology: why we need a new scientific discipline to develop diets and guidelines to reduce the risk of aging-related diseases And is available here: https://pubmed.ncbi.nlm.nih.gov/25470422/ Dr Kris Verburgh is a medical doctor and researcher at the Free University of Brussels where his focus is the aging process, metabolism and nutrition...
Feb 01, 2023•10 min•Season 22Ep. 8
In this episode Dr Verburgh talks about his thoughts on the escape velocity of aging and what it might mean for humanity. Nutrigerontology: why we need a new scientific discipline to develop diets and guidelines to reduce the risk of aging-related diseases And is available here: https://pubmed.ncbi.nlm.nih.gov/25470422/ Dr Kris Verburgh is a medical doctor and researcher at the Free University of Brussels where his focus is the aging process, metabolism and nutrition. He published his first book...
Jan 29, 2023•8 min•Season 22Ep. 7
In this episode Dr Verburgh talks about developments in using mobile phones as a diagnostic device. Dr Kris Verburgh is a medical doctor and researcher at the Free University of Brussels where his focus is the aging process, metabolism and nutrition. He published his first book when he was 16 and his latest is the Longevity Code. Dr Verburgh is a co-founder of NOVOS labs and is a partner and head of science at the Longevity Vision Fund. With that let me start the interview. Dr Verburgh's home pa...
Jan 26, 2023•7 min•Season 22Ep. 6
In this episode Dr Verburgh talks about some of the upcoming technologies which will impact the longevity space in the coming years, including improvements in gene editing and epigenetics. Dr Kris Verburgh is a medical doctor and researcher at the Free University of Brussels where his focus is the aging process, metabolism and nutrition. He published his first book when he was 16 and his latest is the Longevity Code. Dr Verburgh is a co-founder of NOVOS labs and is a partner and head of science ...
Jan 22, 2023•8 min•Season 22Ep. 5
In this episode Dr Verburgh talks about how to optimise our micronutrient intake. This is not simple as it is sometimes difficult to know whether you have sufficient of certain micronutrients just by looking at the blood. Dr Kris Verburgh is a medical doctor and researcher at the Free University of Brussels where his focus is the aging process, metabolism and nutrition. He published his first book when he was 16 and his latest is the Longevity Code. Dr Verburgh is a co-founder of NOVOS labs and ...
Jan 18, 2023•7 min•Season 22Ep. 4
In this episode Dr Verburgh talks what are the key elements of a longevity diet. Dr Verburgh first wrote a paper on this subject in 2015, which introduced the term Nutrigerontology. The paper is: Nutrigerontology: why we need a new scientific discipline to develop diets and guidelines to reduce the risk of aging-related diseases And is available here: https://pubmed.ncbi.nlm.nih.gov/25470422/ Dr Kris Verburgh is a medical doctor and researcher at the Free University of Brussels where his focus i...
Jan 15, 2023•11 min•Season 22Ep. 3
In this episode Dr Verburgh talks about his three (well, he cheats a bit and squeezes in 5!) supplements for aging. Dr Kris Verburgh is a medical doctor and researcher at the Free University of Brussels where his focus is the aging process, metabolism and nutrition. He published his first book when he was 16 and his latest is the Longevity Code. Dr Verburgh is a co-founder of NOVOS labs and is a partner and head of science at the Longevity Vision Fund. With that let me start the interview. Dr Ve...
Jan 11, 2023•7 min•Season 22Ep. 2
In this episode Dr Verburgh talks about the founding of NOVOS and why NMN was their choice for the NAD booster Dr Kris Verburgh is a medical doctor and researcher at the Free University of Brussels where his focus is the aging process, metabolism and nutrition. He published his first book when he was 16 and his latest is the Longevity Code. Dr Verburgh is a co-founder of NOVOS labs and is a partner and head of science at the Longevity Vision Fund. With that let me start the interview. Dr Verburg...
Jan 08, 2023•14 min•Season 22Ep. 1
In this episode Dr Naiman talks about the three forms of exercise, walking, resistance and cardio, trading intensity for duration and the importance of VO2max. Dr. Ted Naiman is a board-certified Family Medicine physician in the department of Primary Care at a leading medical center in Seattle. His personal research and medical practice are focused on the practical implementation of diet and exercise for health optimization. He is the author of ‘The PE Diet’. In the book Dr Naiman explains the p...
Jan 05, 2023•11 min•Season 21Ep. 7
