This episode of Longevity by Design discusses the research behind biological aging clocks, artificial intelligence, and organ-specific aging with Dr. Alex Zhavoronkov and Deepankar Nayak. In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Alex Zhavoronkov and Deepankar Nayak. Dr. Zhavoronkov and Deepankar have extensive knowledge of biological aging clocks—how they are developed, what they measure, how to interpret them, and much...
Nov 16, 2022•56 min•Season 1Ep. 28
This episode of Longevity by Design discusses topics related to regenerative medicine—senescent cells, biomaterials, arthritis, immunology, and more. In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Jennifer Elisseeff. Dr. Elisseeff holds a PhD in Medical Engineering and has conducted many interesting studies relating to tissue engineering and the immune system. Tune in as Dr. Elisseeff discusses the latest science in the field...
Nov 02, 2022•41 min•Season 1Ep. 27
This episode of Longevity by Design is all about longevity medicine, diving deep into the topic of longevity clinics, practical tools for using longevity medicine, and how this approach to healthspan differs from traditional methods of care. In this episode of Longevity by Design, our host, Dr. Gil Blander, is joined by Dr. Evelyne Bischof, Chief Physician Associate of Internal Medicine at University Hospital Renji of Jiaotong University Shanghai and Concierge Longevity Physician for executive l...
Oct 19, 2022•47 min•Season 1Ep. 26
In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Robert Pastore. Today’s episode is all about celiac disease—clinical manifestations, challenges in the diagnostic processes, and how this disease is especially relevant to longevity. Along with having celiac himself, Dr. Pastore holds a PhD in Biomedical Informatics and is a certified nutrition specialist—giving him a personal and unique perspective on this condition. Tune in to ...
Oct 05, 2022•52 min•Season 1Ep. 25
In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Filipe Cabreiro. An expert in the gut microbiome and principal investigator at The Cabreiro Lab, Dr. Cabreiro discusses the latest science on the connection between gut microbial and healthy aging. Join us to learn how to improve microbial diversity and assess gaps in the knowledge that are currently under investigation. For science-backed ways to live a healthier, longer life, d...
Sep 21, 2022•46 min•Season 1Ep. 24
In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Matt Johnson. Dr. Johnson is the Director of Clinical Research at Dexcom—a leading company in diabetes care through the use of continuous glucose monitoring. With extensive knowledge in diabetes, metabolic health, and exercise physiology, Dr. Johnson talks through his research and gives insight into the latest science in the field of longevity. For science-backed ways to live a h...
Sep 07, 2022•49 min•Season 1Ep. 24
In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Dudley Lamming, an Associate Professor at the University of Wisconsin-Madison School of Medicine in the Division of Endocrinology, Diabetes, and Metabolism. Tune in as Dr. Lamming discusses his research on protein restriction and fasting. As the principal investigator of his lab, Dr. Lamming has extensive knowledge of nutrient signaling pathways and how dietary patterns promote h...
Aug 24, 2022•46 min•Season 1Ep. 23
In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Mitch Roslin, Chief of Bariatric Surgery at Lenox Hill Hospital in New York City. During this conversation with Dr. Mitch Roslin, he talks in detail about the obesity epidemic—he touches on taking a preventative, upstream approach, causes, consequences, and everything in between. Dr. Roslin shares his experience as a bariatric surgeon, and the important role this surgery has on o...
Aug 10, 2022•1 hr 2 min•Season 1Ep. 22
In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Krista Varady, Professor of Nutrition at the University of Illinois, Chicago. Research on intermittent fasting is largely conducted in cellular and animal models. Dr. Krista Varady is one of few scientists to conduct intermittent fasting clinical trials in humans. Tune in as Dr. Krista Varady discusses the latest science in the field. For science-backed ways to live a healthier, ...
Jul 27, 2022•44 min•Season 1Ep. 21
In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Ronald Krauss, Professor of Medicine at UCSF, and Adjunct Professor of Nutritional Sciences at UC Berkeley. Tune in as Dr. Ronald Krauss discusses the contributing factors to atherosclerosis, the biomarkers most associated with heart disease, and components of a heart-healthy diet. For science-backed ways to live a healthier, longer life, download InsideTracker's Top 5 biomarkers...
Jul 06, 2022•54 min•Season 1Ep. 21
In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Roger Fielding, Associate Director of the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University. Tune in as Dr. Roger Fielding describes how proper nutrition and being physically active build muscle and prevent age-related muscle loss. For science-backed ways to live a healthier, longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at ...
Jun 22, 2022•43 min•Season 1Ep. 20
In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Mariette Abrahams, CEO, and Founder of Qina , the first hub for data insights on Personalized Nutrition. Tune in as Mariette Abrahams discusses personalized nutrition and how to turn simple actions into sustainable health changes. For science-backed ways to live a healthier, longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast...
Jun 08, 2022•1 hr 2 min•Season 1Ep. 19
In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. George Church, Professor of Genetics at Harvard Medical School. Tune in as Dr. George Church discusses the many roles of gene therapy, including its ability to reverse age-related diseases. For science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast
May 18, 2022•29 min•Season 1Ep. 18
In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Eric Verdin, the President and Chief Executive Officer of the Buck Institute for Research on Aging. Tune in as Dr. Eric Verdin discusses nutrient sensing, epigenetic regulation, and recent research on the impact of foods on longevity. To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast...
May 06, 2022•1 hr•Season 1Ep. 17
Your genetics can uncover many things about you. They can influence how you look and behave, to name a few. But your genes are not deterministic; they don't tell your entire story. In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Ali Torkamani, Director of Genome Informatics at the Scripps Research Translational Institute. Tune in as Dr. Ali Torkamani discusses how genetics impact lifespan and healthspan, why genetics aren't de...
Apr 20, 2022•39 min•Season 1Ep. 16
In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Eran Segal, Faculty Member at The Weizmann Institute of Science in Israel. Tune in as Dr. Eran Segal discusses the value of personalized nutrition, how data contributes to our knowledge of personalized food responses, and the relationship between food and longevity. To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook a...
Apr 06, 2022•41 min•Season 1Ep. 15
In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Raul Mostoslavsky, the Laurel Schwartz Professor of Oncology at Harvard Medical School. Dr. Raul Mostoslavsky has studied sirtuin functions in cancer for many years and has identified a pathway responsible for tumor growth in 30% to 40% of pancreatic cancer patients and more recently identified metabolism as a heterogeneous feature of cancer. Dr. Raul Mostoslavsky discusses the r...
Mar 25, 2022•1 hr 1 min•Season 1Ep. 14
In this episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Steven Austad, Professor and Protective Life Endowed Chair in Healthy Aging Research of the Department of Biology at the University of Alabama at Birmingham. Tune in as Dr. Steven Austad describes how his unique career path from lion tamer to aging researcher has influenced his perspective on the top questions in the field. To learn more about science-backed ways to live a healthier, longer...
Mar 09, 2022•47 min•Season 1Ep. 13
Aging research is quickly evolving to understand how we can live healthier, longer lives. Scientists are looking to centenarians and their family members to reveal how their environment, lifestyle, and genetics contribute to their delayed aging. In this episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Nir Barzilai, Director of the Institute for Aging Research at the Albert Einstein College of Medicine. Tune in as Dr. Nir Barzilai describes how he...
Feb 22, 2022•58 min•Season 1Ep. 12
Recent studies highlight the role of specific longevity agents like rapamycin in slowing the aging process in animal models. Namely, scientists believe that rapamycin, proper nutrition, and caloric restriction may slow down the aging process in animal models and may be transferable to human health. In the latest episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Matt Kaeberlein, Professor at the Department of Laboratory Medicine and Pathology at th...
Feb 08, 2022•59 min•Season 1Ep. 11
In recent years, aging research has shifted its focus from lifespan to healthspan to understand the processes that define aging. Dr. Heidi Tissenbaum’s research investigates the fundamental pathways and genes that determine how we age. In the latest episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Heidi Tissenbaum, professor at the University of Massachusetts Medical School. Tune in as Dr. Heidi Tissenbaum distinguishes between lifespan and healt...
Jan 31, 2022•46 min•Season 1Ep. 10
One topic that Longevity by Design guests can agree on is that sirtuin-6 (SIRT6) plays a protective role in aging and age-related conditions. Dr. Haim Cohen’s lab researches sirtuins, a class of enzymes involved in longevity and aging. He’s specifically interested in SIRT6 and its protective role in the aging process, as well as age-related conditions like cancer, insulin resistance, inflammation, and metabolic health. In the latest episode of Longevity by Design, our co-hosts, Dr. Gil Blander a...
Jan 12, 2022•43 min•Season 1Ep. 9
Inspired by the great unknowns of the brain, Dr. Andrew Huberman pursued neuroscience. From there, he realized that his passion also lay in the art of conveying scientific information in a way that scientists and non-scientists alike can understand. In the latest episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Andrew Huberman. Dr. Andrew Huberman is a tenured professor of neurobiology and ophthalmology at the Stanford University School of Medici...
Dec 08, 2021•1 hr 1 min•Season 1Ep. 8
Did you know that there are species of whales that can live to be over 200 years old? Or that naked mole rats can live up to ten times longer than other mice? These facts and more led scientist Dr. Vera Gorbunova to investigate the mechanisms behind long-lived species and how these can be applied to what we know about aging in humans. In the latest episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Vera Gorbunova, Professor of Biology at the Univer...
Nov 19, 2021•34 min•Season 1Ep. 7
We can’t rely on the magical elixir of life to stay forever young and healthy, but we can change certain lifestyle habits associated with premature aging. In the latest episode of Longevity by Design, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. Brian Kennedy, Professor of Biochemistry and Physiology at the National University of Singapore, to discuss his approach to longevity and aging. Longevity is a complex matter, but Dr. Brian Kennedy explains its most vital details. T...
Oct 30, 2021•40 min•Season 1Ep. 6
Should the elderly engage in physical activity? How do nutrient needs change throughout the lifespan? Researchers and scientists worldwide strive to get revolutionary answers to top aging questions. Our guest is one of them. In this episode of the Longevity by Design podcast, our co-hosts, Dr. Gil Blander and Ashley Reaver, are joined by Dr. William Evans, adjunct professor of Human Nutrition at the University of California, Berkeley. Dr. Evans was the first to describe sarcopenia, the age-relat...
Sep 30, 2021•53 min•Season 1Ep. 5
Dr. David Sinclair is a world-renowned scientist with a rich background in genetics and longevity research. Dr. David Sinclair, Ph.D., A.O. is a geneticist at Harvard Medical School and a Co-founder and Co-chief editor of the journal Aging. He's an inventor on 35 patents and has received more than 35 awards and honors. We're proud to have him on our team as the Chairman of the InsideTracker Scientific Advisory Board. Is aging a disease or a natural process? How can we impact aging on a cellular ...
Aug 18, 2021•38 min•Season 1Ep. 4
The Founding Director of Yale University's Yale-Griffin prevention research center, Dr. David Katz, joins our hosts, Dr. Gil Blender and Ashley Reaver, to discuss the importance of a healthy lifestyle in increasing longevity. We need to prioritize prevention in healthcare. A more preventative approach to health could help postpone and even prevent severe conditions from developing. There are many benefits of adopting better lifestyle habits. According to Dr. Katz, lifestyle is the key to vitalit...
May 11, 2021•1 hr•Season 1Ep. 2
How and why do we age? Is aging reversible? These are some of the most critical questions in biology. Fortunately for us, researchers and scientists across the world strive to get some revolutionary answers. Our guest is one of them. Danica Chen is a Professor of Metabolic Biology, Nutritional Sciences & Toxicology at the University of California at Berkeley. Even though she originally intended to study international accounting, life had other plans, so she switched her major and went in ano...
Apr 15, 2021•30 min•Season 1Ep. 1
