Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode, I will continue the conversation from last session and cover two more Alkaloid Cholinergic drugs like Nicotine and Lobeline. And then the new talk will begin for the new day comprising of details about Choline esters which act directly on the muscarinic receptor, drugs' names being Carbachol, Bethanechol and Methacholine ! Brief account of Smoking Cessation therapy and Historical discovery statement woul...
Mar 30, 2022•12 min•Season 17Ep. 105
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode, I will be detailing each and every Cholinergic Alkaloid Drug like Pilocarpine, Muscarine, Arecoline, Cevimiline, Tremorine and Oxotremorine. Along with the elaboration of details of these valuable gems, I will too discuss Mushroom poisoning (Mycetism) in detail and What more, quick poetic iconic coup d'oeil (Fr. meaning "a look") of "Cherry Blossom" tree through my audiogram!! For all the updates and lat...
Mar 24, 2022•11 min•Season 17Ep. 104
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode i will be briefing the various cholinergic actions via Muscarinic and Nicotinic receptors and finally I will be getting my handle on the names of cholinergic Drugs or Cholinergic agonists. Wishing you all the colourful and best wishes during this festival times, stay blithe and safe... For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also si...
Mar 17, 2022•12 min•Season 17Ep. 103
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In this episode, initially with a quick glimpse of weather, I will talk about Nicotinic Cholinergic receptors. under this main head I will discuss their subtypes like Nm and Nn Nicotinic receptors, their site , their agonists and antagonists and major action, mechanism! For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter...
Mar 10, 2022•8 min•Season 17Ep. 102
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode, I will keep my parle embellished with details about Muscarinic Cholinergic Receptors found in Autonomic Nervous System (ANS). I will be grouping them both as per their significance and also on basis of their function or role. I will discuss all important heads like their location, their mechanism and their role. I will throw enough light on their Agonists and Antagonists. All in all this info storm will ...
Mar 03, 2022•13 min•Season 17Ep. 101
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. Heartiest thanks and congratulations for making upto 100th episode, it's a great, stupendous endeavour!! In today's episode I will be holding important conversations on All about Acetylcholine-it's synthesis, storage, release and degradation. I will be talking about all major steps and major compounds involved in the various reactions and all that affect these different processes! It will be a great information to know........
Feb 21, 2022•12 min•Season 17Ep. 100
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode, firstly I will summarize all we have known so far about Autonomic Nervous System (ANS) , in important bullet points, then I will discuss the Chemical signal interplay in ANS and finally I will be Introducing Cholinergic System or Parasympathetic system briefly, that's the flow of conversations today........... For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult...
Feb 15, 2022•10 min•Season 17Ep. 99
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode, I would be setting my seal upon the Introductory talks about Autonomic Nervous System!! After telling few important exceptions to the general rules of ANS dual innervation, i will be briefing out the discussions about Co-Transmission and Non Adrenergic Non Cholinergic Transmission along with their examples. It feels great to announce that I would be meeting you all charged up zealeously in next episode s...
Feb 06, 2022•10 min•Season 17Ep. 98
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode, I will be drifting further the Introductory swings of ANS, I will furnish details about Enteric Nervous System and also highlight majorly the whole concept of Neurohumoral Pathway/Neurohumoral Transmission. For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of update...
Jan 26, 2022•12 min•Season 17Ep. 97
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. Continuing the trending legacy of ANS, today I will cover overview and brief introduction to Parasympathetic and Sympathetic Nervous System, details about the innervation, different ganglia involved and Neurotransmitters involved. Hope I keep up the interests to set your feet sound and deep in this conversation and conference of Autonomic Nervous System(ANS) , your consistent interest is my goal!! Finally the spirits of wee...
Jan 16, 2022•9 min•Season 17Ep. 96
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. BIEN VENUE 2022! I am here with a new season, a new episode numero uno namely Overview of Autonomic Nervous System (ANS) or Introduction to Autonomic Nervous System (ANS). In today's talk, I will be describing the introductory details of Central Nervous System (CNS) , its different parts, brief descriptions of Somatic Nervous System, Autonomic Nervous System. I will describe the divisions of ANS (Autonomic Nervous System) l...
Jan 06, 2022•12 min•Season 17Ep. 95
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. Bien Venue!! Welcome to the Season 2 Trailer of my Podcast. I will be telling you what we have covered in Season 1 and what we look forward to in Season 2. The essence lies in building blocks of the Castle of Pharmacology, the strong, sturdy anchorage it gonna provide to you all to float easily or dive deep into the sea of this Celebrated Subject!! For all the updates and latest episodes of my podcast, please visit www.isph...
Dec 30, 2021•2 min•Season 17Ep. 94
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. Well! Well! Well! This is the last episode of SEASON 1, and topic of the day is "Drug Antagonism" and YES! I kept my promise to talk about Affirmations for New Year too today!! Antagonism can be of many types like Chemical, Physiological and Pharmacological Antagonisms. Then I will also talk about subclassifications like Receptor Antagonism, Competitive, Non Competitive and their subtypes too! But mantra is to make strong A...
Dec 20, 2021•15 min•Season 17Ep. 93
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. With a good gracious planning to wave 2021 a "CHAO", let us prepare well for new chores in n ew year 2022. In today's episode I will talk about Drug Synergism, its subheads, types, and I will also cover Drug Selectivity, specificity, Therapeutic efficacy, therapeutic Index, (T.I.) , Therapeutic range /Window. All will be clearly described with apt examples, hope you find this verbal talk beneficial!! For all the updates and...
Dec 08, 2021•12 min•Season 17Ep. 92
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. With the winters setting. in, I will be beginning today's episode in a poetic way and finally I will be setting up introduction to Dose Response relation/curves. Today I will cover the shape, importance of log DRC and its significance. I will be discussing three important aspects in this context namely Drug Potency, Drug Efficacy and Slope of DRC with apt examples and descriptions.Finally with a little talk about my two new...
Nov 27, 2021•9 min•Season 17Ep. 91
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. Today is a great Sunday as I am going to mark the end of receptor tale by discussing mainly two heads, namely No Receptor Mechanisms of Drug Action and also a few Receptor Pathologies. It will be a very informative talk and will be of great value at the same time great relief to pave the way to begin a new topic after today!! For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com...
Nov 21, 2021•11 min•Season 17Ep. 90
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. Marking the beginnings of today's episode, narrating the glory and essence of a LIBRARY, I will be talking about the Regulation of receptors. I will thoroughly explain the terms up regulation and down regulation of receptors. I will also talk about connected terms like supersensitivity and desensitisation of receptors. Mechanism. consequences and examples of all these phenomena will be detailed. Hope you all find this episo...
Nov 12, 2021•10 min•Season 17Ep. 89
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. HAPPY DIWALI TO ALL!! In today's episode , I will be talking about enzyme linked and JAK-STAT Transmembrane receptors along with cytoplasmic and nuclear receptors. Season 1 coming to end, BUT BOOK OF SEASON 1 IS ON AMAZON Get your copy at: E-BOOK: https://www.amazon.in/dp/B09KQP36CR Paperback: https://www.amazon.com/dp/B09KN7Y9LK Hardcover: https://www.amazon.com/dp/B09KNCWP1D For all the updates and latest episodes of my p...
Nov 04, 2021•18 min•Season 17Ep. 88
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode,I comment upon the details, structure and mechanism of Receptors which exist as ion channels. They have a special 5 subunit rosette structure ans function primarily via primary ligand modulation which binds to alpha subunit of the channel. For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It...
Oct 28, 2021•5 min•Season 17Ep. 87
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. As a continuation of yester episode, today i will be discussing the three major effector pathways of G Protein Coupled Receptor , firstly the Adenylyl cyclase enzyme-cAMP pathway, then IP3-DAG Pathway, Ion channel regulation,... All will be explained with apt examples and details! Termination of pathways forms a major notable point to discuss, never to be missed.. Wishing you all a very Happy Sunday!! For all the updates an...
Oct 17, 2021•13 min•Season 17Ep. 86
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode I will narrate the famous poem "Windows" by Wes Magee, communicate its amazing message and look into the window of today's topic i.e. G Protein coupled receptors. First and foremost a little word about the receptor nature and types, and then all about G protein coupled receptors, their structure, mechanism introduction and a teaser of upcoming episode too! All in all a good weekend diary to listen to! Hop...
Oct 09, 2021•12 min•Season 17Ep. 85
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode, I will be talking about Receptor drug occupation concept or rather to elaborate dual receptor nature! Receptor exists in two forms, "Ra" and "Ri". On this basis I will define Affinity and Efficacy concept which will further help to understand better the terms like Agonists, Antagonist, Partial Agonist and Inverse Agonist. It really gonna be very interesting and informative to dive in this concept to unde...
Oct 01, 2021•15 min•Season 17Ep. 84
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. Wish you all a very happy international podcast day! Its for both listeners and creators. Together they ROCK!! Together they make podcast happen. Embellishing today's content with decor of sensible stats, I am thankful to all of you! For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of...
Sep 30, 2021•4 min•Season 17Ep. 83
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. Essence of Friendship is in "Sincerity" and "Frankness" of thoughts and words, else it becomes senseless. Today's dialogue is all about Receptor mechanisms of drug action. Actually we are starting it! Initially I will talk about about definition of receptors, and a few more terms to comment upon and define to ge to furnish our concepts and understanding of the detailed theory of receptor action mechanism in a smooth and won...
Sep 22, 2021•8 min•Season 17Ep. 82
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. First and Foremost, a little update from my end is to VOTE FOR MY PODCAST AT- https://www.community.hubhopper.com/hubhopper-awards For my podcast in "EDUCATIONAL PODCAST" Category. A little great expectations, a little request, always remember- One good deed deserves another!! Hope you all VOTE! Today's episode is all about Ion Channels, especially I will talk about Voltage gated Ion Channels(VOC). After discussing the mech...
Sep 15, 2021•9 min•Season 17Ep. 81
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. Firstly its my great pleasure to wish all a very "HAPPY TEACHER'S DAY". Its a great day and yes I am here with a great discussion topic i.e. Enzyme Inhibition. First of all I will define as a ritual, then with no delay I will discuss its two main types, namely Competitive and Non Competitive Enzyme Inhibition. I will discuss their main features or characteristics, the basic mechanism and yes never to miss, never to forget t...
Sep 05, 2021•14 min•Season 17Ep. 80
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode I will be further stating the essence of Pharmacodynamics especially the introductory part! Initially I will be stating various drug mechanisms like Activation, Inhibition, Complexation and Neutralisation. All discussion is supported with examples, then I will tell most importantly that Drug mechanism can be receptor or non receptor mediated. Then I will start off with Elaborations about Enzymes, very det...
Aug 26, 2021•9 min•Season 17Ep. 79
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode, I will be introducing Pharmacodyamics, definition, concept, and try to cover as one line statement, two line statement!! To begin with, today's little contemplation about Criticism, how big deal is it?, how important and wisely you can deal with it, is it really worth a panic? and much more!! And then as our topic proceeds, we will talk about the important drug actions like stimulation, depression, cytot...
Aug 13, 2021•9 min•Season 17Ep. 78
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. I welcome you all to make the podcast sound better cause its a Friday!! Singing the glory of being our best version throughout the week and a wish to start weekend afresh, I will introduce the topic of the day, its actually Therapeutic Drug Monitoring. As our custom, I will be defining it, tell you about its features, when it should be done, when its performance goes in vain and critical steps and conditions to monitor the ...
Aug 06, 2021•11 min•Season 17Ep. 77
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.Marking the celebrated beginnings with essence of birthdays of dear ones, i will quickly follow the ritual of announcing the topic of the day that resounds like Dosing Schedules. In this head, i will talk about drugs having real long half lives, that is more than 24 hours. What are different guidelines, rules, regulations and criteria to administer such drugs especially when they have high volume of distribution. It would be...
Jul 27, 2021•8 min•Season 17Ep. 76
