Robert Lufkin 00:00
Welcome back to the path of longevity show and I'm your host, Dr. Robert Lufkin. And I'm joined by my co host, Dr. Steven siter off so excited about today's session, this is this is this is going to be very interesting.
Stephen Sideroff 00:14
Yes, yes. So, in this session, we will be meeting with Dr. Kamyar Hedayat. Kamyar is a practices a unique form of integrative medicine medicine called endo biagini. He studied at Stanford for two years in pediatric intensive care, and then did a particular follow up in endo biagini, in France, and is now one of the leading practitioners and researchers in the field. So we're very pleased to have you with us today. Welcome, Dr. Hedayat. I'm so pleased to have you joining us in this in this interview. We've known each other actually for a few years and have discussed collaborating on some research. So it's wonderful to have this opportunity to to meet with you.
Kamyar Hedayat 01:09
I'm glad to be with you today to Steven.
Stephen Sideroff 01:12
Yeah. And co host Dr. Rob Lufkin.
Robert Lufkin 01:16
Yeah, it's good to be here. I can't wait.
Stephen Sideroff 01:19
So Todd, let's let's kick off our conversation cambiar by just kind of give us a little sense of how you got interested in the areas of Aging and Longevity.
Kamyar Hedayat 01:33
I became interested in Aging and Longevity from my original training, which was in intensive care medicine. So really being on the cutting edge of life and death. And asking myself, why do some people become so sick, while others don't? And then how do people recover from illness was the beginning of my work. And then I came across the work of Dr. Perico in the dermatologist. And that was the first time I started to think about longevity and aesthetics in terms of skin aging, and thinking about how hormones and food choices affect the quality of our skin. And then from there, I kept going deeper and deeper into how the body manages stress how the mind manages stress? What is the link between those two? And then what is the role of genetics?
Robert Lufkin 02:35
I can't I can't wait to get into all those things. But before we before we dive into each of those points, I love asking our experts just to set the stage on how they think about longevity and aging. In other words, the sort of the 50,000 foot view why why do we age? Why do we grow old? What determines longevity? What what is your kind of working model for that?
Kamyar Hedayat 03:04
Well, my working model is is a three part model witching. And I think that there's an equal interplay. The first is mind, the second is body and the third is lifestyle choices. The mind would be your attitude in life, how resilient you are, as Steven talks about in his work, how accommodating and forgiving how loving you are. There's a lot of research about the positive benefits of gratitude, for example, but I know from my work in my training, that our mental attitude and our mental perceptions have a direct effect on how our body expresses a physical stress response. And that physical stress response can bring wear and tear to the body. So the mental to me is really the starting point. In terms of the role of the physical body, we have to start with genetics. But overlaid is epigenetics, which would be the influence of different factors which can turn certain genes on or off. So we know from really good research that trauma, physiology, trauma, stress patterns can be inherited across generations, by this technique, or this process called epigenetic modification. So it's how your genes are modified in a way that you wouldn't have anticipated them being. So we have genetics and epigenetics, which set the stage about how your body functions and then we have your mother's diet while she's pregnant with you. And then we have the early dietary choices if you were breastfed or bottle fed, how much refined food you ate, and then the choice He says we make as we grow old, and we're independent eaters. And then lifestyle, to me is really a combination of factors that are influenced by our mental attitude and our physical health. It's about the rhythm of our daily life, do we overwork? Are we under working? Do we take time to rest? Do we take time to celebrate? Do we exercise when we want to do something fun? Do we sit down and eat a bag of chips? Do we meditate? Do we believe in a higher power? So lifestyle factors are the great mitigator. Because we can't change our genetics, we can't change our epi genetics. And changing mental attitudes is something that's totally doable. And again, I know that that's been Stephens great work. And he has done incredible work and showing people how to how to do that and become more resilient. But it's not easy work. So when lifestyles important, because those are changes that people can make immediately and in a short period of time, see some improvements in terms of why we age. So to answer the question, why do we age, I would say the more imbalanced, these three big factors are mind, body and lifestyle choices, the more wear and tear we put on the system. The more we accumulate things that shouldn't be there, the more we lose things that should be there that keep us healthy.
Robert Lufkin 06:33
Yeah, I love that. I love that approach. With the mind body, certainly that resonates with what we're hoping to do with this longevity Summit. And then the the lifestyle factor you brought in was great. And if I if I understood you correctly, what you're saying is that genetics play a role. But But beyond beyond genetics, the epigenetics and all the lifestyle factors, those are in our control, and that we we can by taking the appropriate steps influence those factors and, and change change our longevity and and change how we age if we if we choose to. And if we're successful.
Kamyar Hedayat 07:18
I would agree with that. I mean, if you look at the work of Bruce Lipton and others around the Biology of Belief, if you look at studies, where they've shown that people who start meditating in just two or three months, they change the length of their telomeres, which are the end caps on your DNA, which seem to be a good indicator of longevity and biological age, as opposed to your chronological age or your age on your on the calendar. So, absolutely, epi the good and the I mean, the bad news is you can't change your genetics. But the good news is you can change your epigenetics and the epigenetics is the is the ultimate determination of a sort of program of how your body's running.
Stephen Sideroff 08:07
Yeah, can you can you explain endo biagini to our audience?
Kamyar Hedayat 08:14
Yeah. Enter biagini is an approach to medicine, which expands the boundaries of what we're practicing today into something much more holistic. Endo biagini is about looking at the body. Like an ecosystem, like a fine web of relationships, between your hormones, your nervous system, your brain and your psychology, your detox organs, everything is interconnected, everything affects each other. And then Divani creates the pattern and the paradigm to understand how all these things are connected. When we understand that we can work on the field of your health, which we call the terrain and when we can work on the field of your health we can get you back to the potential for longevity and health that you were meant to have based on your genetics and epigenetics or as close to that as we can.
Robert Lufkin 09:14
Allah I love the idea of the endo biology and the terrain model and as especially as a as a physician coming from and still at the sort of the the Orthodox academic medicine How does endo biology money compared to other other schools like like functional medicine or integrative medicine? Which how do you how do you compare those two are they all pretty much doing the same thing as far as approaching the terrain and and sort of root causes which I think is a really powerful concept that that they're all three getting at somehow?
Kamyar Hedayat 09:58
Yeah, you know, I want to say say that everyone working in this field is doing amazing work. My explanation of the difference is not to say that one is better or worse, but just to kind of say, Well, what exactly is the difference? I would say that functional medicine is an approach to the terrain where the field of health is really still based at the level of cells and tissues. And, in contrast, endo botany is looking at all the different levels. It's what we call a fractal model, or holographic model, kind of like Patricia dolls, those Russian dolls, where one is inside the other. So we're looking at the whole body, as a field, and inside the field of the body are all the organs inside the organs, or the tissues inside the tissues or the cells and inside the cells are the genetics. And we say, why stop at one level of analysis when you can run through all of them and get the biggest picture possible. Integrative and then in its army, then integrative medicine is a field which is an approach which I would say is more like a salad, then a soup, because integrative medicine is a movement, which seeks to place a standard orthodox approach next to non orthodox approaches and say, Hey, we're still in charge, because we've got the reimbursement model and where the authority figures, but if we can't figure it out, we're gonna toss you a bone and let's see what you can do. So I would say integrative medicine is saying, Okay, there's a big tent, and there's a place for people who aren't doing surgery and prescribing medications, but you're always second. And about journey, instead of being integrative is integrating. And integrating means bringing everything in and making these connections. You know, as an endo biologist, I don't give any privileged priority to any approach. I always tell my students that I trained and I always tell my patients, everything's on the table. Everything's on the table surgery, chemotherapy, medication, herbs, meditation, homeopathy, acupuncture. The only question is, what's the best thing for you right now to maximize your healing and come to a new state of stability?
Robert Lufkin 12:37
Yeah, I love the idea of the endo biagini. And just one follow up on that. Steve mentioned you and you had training in France for that. And you mentioned that you train healthcare workers here in the US in that? Is there any sort of certification program or credentials when someone looks for an endo biogenic oriented healthcare provider? What should they look for?
Kamyar Hedayat 13:04
Yeah, I've been teaching and debauchery around the world in North America and Europe and North Africa. Since 2012, and right now, we're getting ready to start a new program that will be easier for doctors to learn. And they can go to our website, learn endo biagini.com. And they can learn more there. I've also published a four volume book series that anyone can purchase on Amazon or at the website of Elsevier, who is the publisher of that it's also available in French for any of your French speaking audience members. They can go to French, Amazon amazon.fr, and look and just type the word endo botany. And they'll see our books there too. So that's a great way to learn. And then my mentor and endo biagini, Dr. Le Praz, la pra Z, wrote a fantastic book with a journalist for the general public. And you can get that in English at Amazon, if you type LaPrise la pra Z or at French Amazon as well.
Robert Lufkin 14:15
Great. I just before we move on from that this is such an important topic, I wanted to just reach back and ask you to expand a little bit about the role that that you so beautifully explained about resilience and the mind and how that plays in the model.
Kamyar Hedayat 14:34
Oh, yeah, sure. Well, you know, within the brain, so I want to make a difference between the brain as a physical organ and the mind. The mind to me is a type of event. It's conscious, it's consciousness, it's awareness, plus the role of the physical brain and the nerves in the brain, the neurons to express these electrical in pulses that allow us to think in the physical world. But the brain has a special area called the limbic area. And this area called the limbic area is like a Grand Central Station, where nerves from the brain, nerves from the fight or flight, nervous system, and input from the hormones all meet. And they kind of get together and they say, Hey, what are you doing? Are you stressed out? Are you worried, and any one of these three systems, your your mental attitude and perception towards stress, your nervous systems tension, and your hormones can tell the other ones, I'm feeling really jacked up, I'm really feeling worried. And the other systems will say, Okay, I'm going to get worried too. And we're going to work together to create a big stress response. And so the mind is important in and of itself, because it's, it's really the entryway into the whole stress, hormone response, and aging. Because in the world modern world we live in. We're not constantly faced with threats of survival, unless there's war, or people are living in a jungle in very primitive or basic conditions. So most of us who are living in cities living in suburbs, Our problem is not existential survival. Most of our problems are coming from our perception of the world around us. You know, somebody talked bad about me at the Parent Teacher Association. You know, the AARP changed their policy, and it's really making me mad. There's all sorts of things a driver cut me off. Most of our stressors are unnecessary stressors. I estimate just from my clinical experience, probably 60 to 80% of the physical stress response is coming from mental issues, that didn't need to be an issue. And so to me, the mental part is really important. And when I started, when I left intensive care medicine to practice endo botany full time in the clinic, I was really focused on the physical aspects of health. But I realized after a couple of years, that there were patients who just hit a plateau, and I couldn't get them physically any better. And then I started to ask about their traumas about early childhood traumas, what we call adverse childhood events and adult traumas. Then I understood that the bigger the trauma was, the bigger the barrier to getting to that full healing potential, and having optimal longevity. And then I started working in the field of what we can call psycho dynamics, helping people understand different parts of their mind that are creating those attitudes and how they can evolve out of that to have more resilience. And that was a real game changer in me helping people age better, and maintain their best potential to live a full life as they get older.
Stephen Sideroff 18:16
That's a, I really appreciate that response. And I couldn't have said it any better than you were, you're really talking about mindset, how we frame things perspective and things of that nature and in their impact. So I appreciate that response.
Kamyar Hedayat 18:34
Steven, can I just say, I couldn't say it any better than you, because your book was on the nine fold path. And resilience was so impactful, and so well written, and it's a book that I've referred so many patients to, because it is so well written, and it is such a great pathway to developing this mental flexibility to deal with stress better in life.
Stephen Sideroff 19:02
Thank you. Yeah, I'm sure that one of the things in our conversations you've talked about about endo biagini is how it can detect imbalances way earlier than other approaches. And this gives you a leg up on on how to deal with it. Can you go into that, please?
Kamyar Hedayat 19:26
Yeah. So, from our work in endo Bochy, we developed a special analytical software. That takes bloodwork common bloodwork that doctors order all the time, like a simple blood count or electrolyte panel, but then also some specialty labs and the software is able to detect imbalances between the different blood tests. And that helps us create a model of where people are at in the global functioning of their Whole body their whole terrain. And so in this way, there are certain disorders that take years or decades before you actually feel it or see it. Most of us are familiar with the concept of pre diabetes, or pre hypertension, where our blood pressure is in the upper range of normal, it's not quite high enough to start a medication. But we see what's coming down the road. And the same thing with diabetes. Well, what we found in our work over the last 50 years is that there are all sorts of other three disease states. And if you understand the genetics, the family history, how the detox organs are functioning, and the mental attitude, if you take all that information, and then you look at the analysis through our software program, you can start to see pre pre disease states pre cancer, pre aging, pre Alzheimer's, if we know somebody has a disorder, but it's currently controlled, we can we can say, You know what, I see something that looks like you might have a flare up in the next three months. And when I talked to folks on the next follow up consultation, they're like, Doc, you said it, and and it happened, you know, and so for me, preventing Well, I mean, just like I think, Benjamin Franklin said that an ounce of prevention is worth more than a pound of cure. So it's always better to prevent than to have to get behind the eight ball and try to cure something later on. And that's what I love. With Bhatinda balcony and using our testing system called Gemma.
Robert Lufkin 21:46
I'd love I love the idea of doing the test for the early detection or preclinical detection of these these important chronic diseases. I I'd be curious. Maybe you could talk a little more about Gemma be interested in hearing that? And also, is there are there different markers that indicate aging in itself? Or basically do the same markers that that indicate risk for cancer indicate aging and risk for Alzheimer's disease indicate aging because they're they're so closely intertwined?
Kamyar Hedayat 22:24
Yeah. Rob, you asked really a great question. Gemma, which stands for Global endo biagini, medical mathematical assessment is founded Gemma bio G mm a big o.com. It's a website that doctors can use, they can register for free and enter the labs of their patients. And and benefit from the power of this analytical system. And so, the the, the the concept of aging is really about degeneration. And we have this concept and then to biagini that we borrow from a French term, which is d installation, which is when the body starts to basically want to close up shop. So there are things that we notice, say a decade before people start to kind of feel old, so to speak. And I've developed formulas for the system that can show a general risk of aging and degeneration when the body's not using something called autophagy. autophagy is the system for the listeners where your cells basically have a natural garbage disposal system. They'll take waste products and toxins and they'll they'll destroy them inside the cell. And there was a Nobel prize that was awarded for the couple of years ago for the doctors who and the researchers who just discovered a toffee G. But we can look at this, we can model and estimate autophagy and where people are getting stuck and that's a first sign of degeneration and aging. And then I noticed other things in our Gemma system, like all of a sudden, red blood cells than white blood cell levels will go down and people don't have enough testosterone for vigor and vitality. And then we'll start to see their metabolism go low and then their pancreas isn't working well to break down food that's why people find themselves eating more soup and the you know, boiled food and steamed fish and lighter and lighter food because they're having trouble digesting these are all parts of this D installation where the body's like well I'm getting ready to close up shop and we can reverse it as long as we come in soon enough and bring back that vigor and vitality.
Robert Lufkin 24:52
Yeah, the love the Gemma test. That's such a fascinating approach to But where it's all integrated, and hopefully people will check out that website. One question, I guess, a toffee G. All of all of our experts, everybody pretty much agrees of the fundamental role of a tapa G as one of the key things with aging. And I guess the challenge that everybody faces is that it's, it's so hard to to measure a toffee g by itself. What, what lab values do you find most important for a toffee G? Or what? How do you rely on what do you rely on to characterize it?
Kamyar Hedayat 25:33
Yeah, well, the formula developed is very complex in the sense that there's like five or six other formulas in the numerator on top. And then there's a whole bunch of other formulas in the denominator on the bottom. But basically, if you wanted to look at the raw lab data, thyroid stimulating hormone, very important, irrespective of whatever your level of thyroid functioning is osteocalcin, which is a bone protein, which actually has a bigger role in helping your cells outside of the bones maintain their metabolism, because osteocalcin increases the number of mitochondria for energy production, it improves insulin sensitivity and improves estrogens role in transcribing the genetics around protein metabolism and building enzymes to help your cells function better. So osteocalcin is very important. The third one I would say, which is very important is alkaline phosphatase, bone isoenzyme. So I know we're getting kind of wonky with the details. But these are important. And but actually, I don't measure autophagy, because it's really not practical, but we model or estimate it, and actually estimated in six different ways, three ways or what's going on at the level of the cell. And then the next three are, how is the whole body's stress response, making it harder for cells to use autophagy. And based on which ones of these, which level of analysis, the problems that we can use different types of approaches, maybe it's tweaking thyroid stimulating hormone by starting someone on low dose of thyroid medication or optimizing their dose, if they're already on it, we could use iodine or it will encourage them to eat more seaweed in their diet as a natural source of iodine and other healthy factors which help the body cleanse. If it's at the cell level, maybe we need to use Coenzyme Q 10. Sometimes I tell people, you don't have enough oxidation, I want you to use hyperbaric oxygen, to really get the oxygen into the cell. And that'll stimulate your cells to to do some housekeeping and cleanse out those toxins. So that again, that's what I love about the Gemma system is that I don't I don't guess what to give my patients. The system tells me very clearly you need this level and nobody has to take anything they don't need. Because it's really targeted and personalized to who the person is and what their specific imbalances are.
Robert Lufkin 28:12
And if the one fault, one follow up and I'll hand it back to Steve the on the on the increased top or if in order. If the autophagy markers are low and autophagy is good, we want to increase it what what particular approaches do you recommend for that and you know, some of our other speakers of record, you know, talked about rapamycin or descent nib as senolytics or autophagy increases, what is your approach to increase autophagy in a patient who who needs it?
Kamyar Hedayat 28:48
Well, again, all all options are on the table for me I once I have an abnormal autophagy score, then I triangulate it to other factors. So for example, we have an index or a formula in the Gemma's system, which looks at us apoptosis, which is natural cell death. But this specific version of the estimation is saying, Hey, do you have traumatic apoptosis, and that that index is linked to chronic low grade infections or physical trauma? So if that's the case, then I think something like rapamycin is a good idea. Sometimes I use minocycline. It really depends. If cortisol is low and we need to boost things. I'm not opposed to using a one month up and down course of steroids. But most of the time, probably 80% of the time, I'm using natural remedies. There are there are remedies like birch or Juniper, which are really good for helping the liver and kidney cleanse. I might want to use Add something like Coenzyme Q 10, as I mentioned earlier to help improve mitochondria, and their production of cell energy called ATP. I always, I always triangulate one result to two or more other results to personalize the approach. Sometimes Metformin could be the right approach, and people want to use the medication, because that will improve insulin resistance. And that could be a key as well. And sometimes I use, I investigated for low grade infections, and I'll use something like cat's claw, or I'll use a combination of doxycycline and azithromycin for four to six weeks.
Stephen Sideroff 30:45
Maybe we can focus in on an area I know that you have a particular interest in and is very relevant to this topic. And that's Alzheimer's disease, both preventing and, and early identification. Can you tell us a little bit about how you got interested in that? And then how you how you approach that from an endo biology perspective? Yeah,
Kamyar Hedayat 31:11
thanks, Steven. I, in the course of my work, I started to have patients who had a very strong family history of Alzheimer's disease, typically there would be three or more relatives in the generation just about them, like mom, you know, an uncle and two aunts, or some combination like that. And they said, Doc, I don't want to get Alzheimer's like the folks in the generation above me, or like my older sibling already has it. And I started to notice these patterns in the Gemma's system, and the developer of vendo biagini had a theory of how Alzheimer's started. And I I, I based my study on what he identified, which is how those plaques those amyloid plaques form in the first place. And based on that, I created some new formulas to triangulate this process using some more modern research, including the important role of loneliness, and this psychological variable of feeling isolated socially. So I look at my the Gemma results, given a family history, and I say, Okay, right now you don't have a risk or you do have a risk. And, and then what I do is I look at the companion results in Gemma, that that indicate this is what you need to change is that their thyroid? Do they have, for example of functional hypothyroidism where their numbers are normal? But their cells aren't sensitive enough? Do they have too much inflammation? How are their mitochondria doing? Whatever the problem is, that comes up in the Gemma panel, which is sort of like a functional profile of Alzheimer's risk. We just target that. And then three months later, we repeat the bloodwork and and the numbers are getting better. And clinically, I say can you remember things when you walk in a room? They're like, yeah, like you remember directions when you're on the highway. They're like totally. And another thing I noticed, which was so compelling, is that I had a group of these patients who one year into treatment, stopped everything without telling me and their numbers all reversed. And then I started them on treatment again, and their numbers got better again, and I'm like, I think I'm onto something here. And it was really the evidence I needed to see how important certain variables were and how to treat them.
Robert Lufkin 33:56
Yeah, that's that's fascinating it. And we we've been hearing from Dale Bredesen and some of the others on doing similar things with like targeting the toxins certainly plays a role correcting deficiencies. And then above and beyond that, you mentioned lifestyle things like stress and exercise. How about nutrition? Is there any is there any consistent nutritional recommendations for people to decrease their risk of Alzheimer's or or hopefully even walk back some of the symptoms that they already have it?
Kamyar Hedayat 34:34
Yeah. Well, I think that you know, being on an anti inflammatory diet is as a general principle, very important, but this the, that general advice is too vague. Because in my experience, and when you look at the nutrition literature basically I will put it this way If you look at the three big nutrient groups, so you have proteins, you have carbs and your fats, what I've observed is the reason that there are so many diets that are successful is that they all do one thing, they have one thing in common, which is they tell you the two out of these three groups and minimize the third. Because if you look at a paleo or a keto diet, you're eating proteins and fats and avoiding the carbs and the blood sugar spikes. If you're on a Mediterranean diet, it's more of whole grains as the source of your carbs, and vegetable bases of your all of your fat with lean proteins, so it's really more protein and whole carbohydrates with little fat. And, you know, the point is, you can reduce inflammation through various selections of these macronutrient groups. And again, in the Gemma's system, we have modeling of cellular level nutrition, which is so we're looking at something called Cell permeability, which is How soft your cell membranes are. Are they soft? Are they firm? How much do you depend on passive movement of nutrients, small molecules of nutrients? Just through the membrane? How much do you need receptors to help bring in nutrition I look at this insulin, insulin resistance and other factors. And then I say, okay, for you to reduce inflammation, you need to be more on a paleo or keto diet, or I want you to do some intermittent fasting, or I want you to be on more of a high fiber Mediterranean diet. So, you know, anti inflammatory is great. I think it really needs to be personalized to the type of person and there's many ways to get an anti inflammatory diet.
Robert Lufkin 36:51
Yeah, the the, that's great advice on the low carb, low carbohydrate, recommendation I we're seeing that pretty much consistently for most of our speakers. The one other nutritional recommendation that comes up and I wanted to get your take on it, as far as inflammation was, in addition to lowering carbohydrates, was also something with fat, and that was to avoid industrial process seed oils that like that are high in linoleic acid, the Omega six versus omega three ratios. Do you feel is that important for your your program? Or is it mainly the carbs that people should focus on?
Kamyar Hedayat 37:35
It's, it's, it's everything, I always try to consider everything all at once, because the seed oils are important. But you know, if you're using olive oil, but your heat overheating it, and it's smoking, and then you're frying something that's probably worse than using a refined seed oil at a lower temperature. You know, I think it there's a little bit of nuance here, when you get into the nitty gritty of everyday living from my perspective, but in general, I would say, if people could fry food as little as possible, or use water, as a type of saw tank to soften food, and focus more on baking in parchment paper to seal in the juices and the moisture. In more steamed vegetables, this would clearly be the optimal way. And then something like olive oil is best used on top of the food as a lubricant for taste and as a calorie source because olive oil is a healthy fat, and it's good to have some fat in your diet.
Stephen Sideroff 38:41
These are very useful pieces of information for our audience camera. Thank you. Thank you getting back to the Alzheimer's question. It seemed to me you were referring to people who were trying to prevent the onset of Alzheimer's and so you were putting them on certain regimens and you're seeing their Numbers that relate to potential shift. What about people who may be already in that process of of having the disease or you're finding any of your approaches helpful for that population.
Kamyar Hedayat 39:23
I've only found them helpful for early stage, full onset Alzheimer's, that it's the same indicators and the Gemma's system. They're just more extreme in their range of their abnormalities either too high or too low. But honestly, I haven't found a lot of good success in later stage. And my conclusion about that because I give treatments and the numbers in the Gemma's system improve, but the clinical condition doesn't improve. And we're having worked with Fe Emily's, my conclusion is that what we're not changing is the psychology of the loneliness. And I really think that there's an underappreciated value of a person's willful desire to be isolated from the world and kind of check out. And part of my treatment and pre and early Alzheimer's is to work with psychodynamics, to talk about trauma. And I use different types of remedies, including some Homeopathics that I found, really help people start to come out of that feeling of loneliness and isolation. I really think this is beyond the nutrition beyond the hormones, we've got to understand the psychology of isolation, because what is all what is Alzheimer's at the cellular level, your cells are being isolated behind a wall of amyloid plaques. And in a sense, your emotional heart is being isolated behind this wall of being kind of checked out.
Stephen Sideroff 41:07
Yeah, I can really appreciate that. Because what you're describing when you say people who want to check out that to some degree describes people who are depressed. And there's all kinds of research that shows increased risk of all kinds of disease with depression.
Kamyar Hedayat 41:28
Yeah, I find that, you know, if you think about a Venn diagram, or these overlapping circles, and you put Alzheimer's disease, in the middle of it, you're going to have an overlap with depression, you're going to have an overlap with trauma, you're going to have an overlap with anxiety with type two diabetes or adult onset diabetes, you have overlaps because they're sharing some common symptoms like insulin resistance, like insufficient autophagy, inflammation. But when they all come together at the same time, that's Alzheimer's, in the face of somebody who feels lonely, and wants to check out. And let me just say, as a side, note that I have a lot of patients who say, Doc, I think I have dementia, I can't remember things. And it's tip of the tongue and all these things. And what I also really like about using the Gemma system is I can say, it's not Alzheimer's, your problem is not that your brain is running too slow. It's actually running too fast. It's running so fast, you can't organize your thoughts. But I don't want you to worry about Alzheimer's, that's not where you're at. And actually saving again, I recommend that people do neurofeedback, which is one of your specialties. And I find that that helps meditation. Again, we can use some herbs to help the brain slow down. So you feel like you're in control of the carriage so to speak, and the horses aren't just pulling your mind around in every direction. So
Robert Lufkin 43:09
yeah. Well, we've covered a lot of different fascinating topics today, I want to back up and just hit on one more thing, maybe about longevity in general, are there? Are there any areas of longevity that you're excited about longevity research that maybe that you're not working in directly? But what do you what do you see is the future for longevity, the things that really get you excited?
Kamyar Hedayat 43:35
Well, I think the future of longevity needs to be working with 40 and 50 year olds, and optimizing the trajectory as early as possible. And so I think that the research that's been going on in understanding early and very subtle signs of dysfunction is really the most promising because if we continue to live in a crisis culture, which just wants to react to a problem, once it's there, we're really not going to move the ball down the field on longevity, right? The investment in longevity starts, when we're still feeling good and healthy. Of course, you can start at any time, and you can get some level of improvement. It's never too late to expand your capacity for vitality and health. But the earlier you start, the better your results. So I'm really excited about research that's looking at slowing down the aging through this whole person model, your psychology, your epigenetics, your diet, your lifestyle, all together.
Stephen Sideroff 44:48
So you've during our talk today, you've really touched on a lot of areas and a lot of things that people in general can can do. As we close can you identify a couple A lot of recommendations you would give to our audience that would show sign would show improvement.
Kamyar Hedayat 45:09
Oh, yeah. In terms of their general longevity, yes. You know, this is gonna sound a little simplistic, but with all my training and all my years of experience, my my path has come to the simple observation, that fresh air, clean water. Recognizing when you feel tired and taking a nap, or just closing your eyes for a few minutes and doing deep breathing, or what I call rhythmic living, these are probably the three most important things that a person can start doing right now today to improve their health. And there are so many studies that indicates the importance and the positive effects on reducing inflammation, reducing stress, improving insulin, blood sugar management, just from these three steps. I guess if I want to add one more thing it would be movement does, as they say, sitting is the new smoking. And studies. Newer studies have shown that if you sit for four hours at a time or all day to desk, even when you're exercising a couple of days a week, it doesn't reverse all of the harmful effects of sitting down all the time. And so getting up and frequently moving around parking at the end of the parking lot and taking the long way to the store, you know, walking up a couple of flights of stairs, if your knees are okay with it. These little decisions every day are seriously the most impactful things you can do. You don't need to get a supplement, you don't have to do a blood test, you don't have to see a doctor for it. It's totally in everyone's hands to do this. And this is where I would start.
Robert Lufkin 46:54
Now, um, er, you mentioned a couple of websites that people can go to maybe what's the best way for people to reach you on social media or your own personal website?
Kamyar Hedayat 47:05
Yeah, Thanks, Robert. The best way to reach me is either through my medical practice site, which is called f s. H center.com. For Full Spectrum Health, or through our professional community website called Learn endo biagini. En do big o gny.com. And on you can find me on Facebook and on Instagram under learn endo biagini. And my my website Full Spectrum Health Medical Practice. Very good. Okay,
Stephen Sideroff 47:47
thank you. Again, it's been a pleasure to talk with you and really get your perspective which is a really global comprehensive perspective. So, Kenya, I thank you very much for joining us.
Kamyar Hedayat 48:03
I enjoy the conversation. And I want to just express my gratitude to both of you for creating this forum and a place where the best minds can get together and share their knowledge with everyone. Thank you.
Unknown Speaker 48:16
This is for general information and educational purposes only. And it's not intended to constitute or substitute for medical advice or counseling, the practice of medicine or the provision of health care, diagnosis, or treatment, or the creation of a facility, physician, patient or clinical relationship. The use of this information is of their own own users risks. If you find this to be on the value of please hit that like button to subscribe to support the work that we do on this channel. And we take the your suggestions and advice very seriously. So please let us know what you'd like to see on this channel. Thanks for watching and we hope to see you next time