What if everything we've been told about Alzheimer's disease is backwards? Dr. Dale Bredesen, author of the New York Times bestseller "The End of Alzheimer's," returns to our program to shatter conventional wisdom with research showing cognitive decline can be prevented and even reversed. The traditional approach to Alzheimer's has failed spectacularly. Despite billions in research funding, pharmaceutical solutions have delivered minimal benefits. Why? Dr. Bredesen reveals the fundamental misund...
Mar 25, 2025•37 min•Ep. 199
What if the future of healthcare lies in our ability to decentralize it? This episode takes us on an insightful journey with Jasmine Smith, the visionary CEO of Rejuve AI. She shares her fascinating transition from health information management to leading a groundbreaking project in decentralized health and wellness. The transformation from Web 2.0 to Web 3.0 is laid bare, with Jasmine revealing how this evolution empowers individuals by taking control away from traditional central entities and ...
Mar 18, 2025•42 min•Ep. 198
This week we unlock the secrets to a healthier, longer life with insights from Dr Robert Lustig as he unpacks the hidden dangers of junk food. Ever wondered how ultra-processed foods sabotage your body's natural functions? Discover how the fructose in these foods disrupts your mitochondria, leading to serious health issues like fatty liver disease and insulin resistance. Dr Lustig contrasts these effects with the benefits of whole fruits, which offer protective fibers to mitigate damage, equippi...
Mar 11, 2025•48 min•Ep. 197
Conventional cancer therapies may be missing additional opportunities for healing. The recent breakthrough publication showing brain cancer three year survival rates of 66% on a ketogenic diet versus 8% on a regular diet highlight this possibility. [ https://t.co/dsU7hD71Wv ] This week we discover why our guest believes the real battle against cancer is fought at the metabolic level, not through DNA-focused treatments. Join me as we sit down with Dr. Katie Deming, a former radiation oncologist w...
Mar 04, 2025•41 min•Ep. 196
What if adopting a new mindset could transform not just how long you live, but how well you live? Join us as we explore this possibility with Dr. Nick Engerer, a leading expert on longevity and health optimization. Drawing from his personal journey that started with a wake-up call in his twenties, Dr. Engerer reveals the secrets to embracing a longevity mindset. Through his experiences with cutting-edge technologies at Human Longevity Inc., he shares how early disease detection is revolutionizin...
Feb 25, 2025•37 min•Ep. 195
This week we get to unlock the secret to better health with Dr. Richard Johnson, a leading mind in the field of sugar metabolism, as he reveals the hidden dangers of fructose and its surprising role in metabolic diseases. Dive into the science of sugars and uncover the biological mechanisms that make fructose a stealthy culprit for obesity. While fruits like dates and figs may seem harmless, their high fructose content is a concern, especially when consumed in juices. Dr. Johnson demystifies the...
Feb 18, 2025•35 min•Ep. 194
This week we explore the secrets to a longer, healthier life with our special guest, Dr. Gordon Lauc, a renowned professor of biochemistry and molecular biology. In today’s episode, we promise to transform your understanding of aging by introducing a revolutionary approach to measuring biological age through glycosylation. Unlike the familiar concept of glycation tied to sugar levels, glycosylation involves complex enzymatic processes that impact our immune system and overall health. Discover ho...
Feb 11, 2025•43 min•Ep. 193
Citizen scientist and entrepreneur Daniel Trevor joins us for an eye-opening discussion on his profound journey through cardiovascular health. Following a life-altering heart attack, he utilized his tech data analysis skills to question conventional medical practices and explore the depths of medical and nutritional science. Daniel's story underscores the importance of independent inquiry and challenges long-held beliefs, offering listeners a fresh perspective on cardiovascular care informed by ...
Feb 04, 2025•45 min•Ep. 192
Can our dietary habits be a missing link in the quest for better mental health? Join us for a thought-provoking conversation with Georgia Ede, a Harvard-trained psychiatrist renowned for her pioneering work in nutrition science and brain metabolism. As chronic diseases like obesity, diabetes, and mental health disorders surge, Dr. Ede unravels the hidden connections between our diets and mental well-being. Brace yourself for some bold insights as she challenges the widespread consumption of refi...
Jan 28, 2025•44 min•Ep. 191
Unlock the secrets to super longevity with James Stroll, a visionary in the pursuit of unlimited lifespans. Discover how James and his partner, Bernadine Brown, have been at the forefront of advocating for immortality since the 1970s. Despite facing skepticism and a lack of scientific backing, their relentless passion built a thriving community dedicated to wellness and longevity. Their journey led to the creation of RadFest, a groundbreaking conference that bridges the gap between scientific ad...
Jan 21, 2025•31 min•Ep. 190
The episode dives into the transformative perspectives on aging and longevity provided by Dr. Jeffrey Gladden, one of the leaders in longevity science, who emphasizes that aging should not be viewed as a decline but as an opportunity for vitality and growth. The conversation explores the Five Circles of Longevity, the deconstruction of individual health profiles, and the importance of integrating psycho-spiritual health with physical well-being to foster a youthful mindset, ultimately urging lis...
Jan 14, 2025•53 min•Ep. 189
Discover the future of testosterone replacement therapy as we welcome Shalin Shah, the visionary CEO of Marius Pharmaceuticals, who has made the bold leap from an investment background to the forefront of medical innovation. Shalin shares his journey and unveils Kyzatrex, the FDA-approved oral testosterone that promises to change the game by sidestepping the liver toxicity risks associated with earlier oral options. With Kyzatrex’s novel lymphatic absorption method, we showcase why this advance ...
Jan 07, 2025•45 min•Ep. 188
Join us for a thrilling journey into the world of biohacking with our guest, Jean Fallacara, one of the founders of the biohacking movement and editor of Biohackers Magazine with an audience of over 5 million. Discover how his extensive academic background in biochemistry, genetics, and artificial intelligence fuels his mission to make biohacking accessible to everyone. Jean shares his unique vision for optimizing life, focusing on enhancing the quality of living rather than merely extending it....
Dec 31, 2024•46 min•Ep. 187
As we approach the end of the year, I want to take a moment to reflect on the power of gratitude, peace and well-being. This season reminds us to cherish the connections we've built, the lessons we've learned and the moments of joy and growth we've experienced. I'm especially grateful for you, our listeners and supporters, who, encouragement, makes it possible for us to share our message and reach so many more people. Together, we're fostering conversations that inspire health, longevity and a v...
Dec 24, 2024•37 min•Ep. 186
What if your healthy snack could support both your body and the planet? Tune in as Yuda Holzberg and Jon Engelson, two pioneers in the world of grass-fed, pasture-raised kosher beef snacks, join us to unravel the mysteries behind your favorite meaty treats. With a promise of uncovering the nutritional treasures of beef as a low-carb, high-protein powerhouse, we tackle the realities of modern meat production and the pressing need for transparency and sustainability. Whether you're a committed car...
Dec 17, 2024•35 min•Ep. 185
This week we get to unlock the secrets of rejuvenation with Dr. Amir Hadanny, a pioneering neurosurgeon and advocate for hyperbaric oxygen therapy, as he reveals how this cutting-edge treatment is transforming the landscape of neurological recovery and longevity. You'll gain insights into how hyperbaric medicine optimizes healing by harnessing the power of 100% oxygen, triggering repair mechanisms, fostering stem cell proliferation, and encouraging angiogenesis, all within the confines of a pres...
Dec 10, 2024•34 min•Ep. 184
Ever wondered how you can achieve the health benefits of fasting without actually abstaining from food? Join us as we explore this intriguing concept with Dr. Joseph Anton, CEO of L-Nutra. Dr. Anton introduces us to the innovative idea of physiological or cellular fasting, where specific nutritional choices can simulate the body's fasting state. We delve into the popularity and benefits of intermittent fasting, particularly the 16-hour fasting pattern, and examine how our bodies switch from glyc...
Dec 03, 2024•40 min•Ep. 183
What if you could revolutionize healthcare from the palm of your hand? Join us in a captivating conversation with Jacob Peters, a visionary in the realm of integrative health and entrepreneurship. Inspired by his mother's struggle with chronic cluster headaches, Jacob shares how his early exploration of alternative health solutions laid the groundwork for his successful software company and his mission to transform the healthcare landscape. His journey is not just about personal triumph but abou...
Nov 26, 2024•40 min•Ep. 182
Ever wondered how a simple curiosity can lead to a life-altering journey? Meet Sandy Martin, the dynamic founder and CEO of Biohacker Expo, as she reveals her extraordinary transformation from orchestrating Comic Cons to becoming a biohacking pioneer. Struggling with severe health issues due to mold exposure, Sandy's relentless pursuit of wellness opened the door to the vibrant world of biohacking. She shares her inspiring story and advocates for a citizen scientist approach, empowering you to t...
Nov 19, 2024•1 hr•Ep. 181
Imagine unleashing the potential to monitor and optimize your health right from your living room. That's what we discuss with Dr Michael Dubrovsky of Siphox Health in an enthralling conversation about the leaps in at-home blood testing technology. Note Full Disclosure: Siphox Health is a sponsor of this podcast but we only allow sponsorship by products and services that we believe in. Michael's journey from biochemistry and photonics to pioneering consumer-friendly blood testing devices is nothi...
Nov 12, 2024•39 min•Ep. 180
This week we look at the secrets to a longer, healthier life in our exclusive conversation with Dr. Walter Longo, a pioneer in longevity and healthy eating! Embark on Dr. Longo's incredible journey, from his transformative experiences with Dr. Roy Walford at UCLA to his groundbreaking research on fasting. Discover how periodic fasting and fasting-mimicking diets can reset your metabolism, and learn about his innovative "summer mode" and "winter mode" eating patterns that can revolutionize your d...
Nov 05, 2024•32 min•Ep. 179
How young are we really, on a cellular level? This week we are joined by Chris Mirabile, a brain tumor survivor and the visionary CEO of Novos, shares his journey of significantly reducing his biological age. In full disclosure, I am a scientific advisor to NOVOS but I only affiliate with those companies that I believe in. Chris discusses the difference between chronological and biological age and learn how advanced epigenetic tests can offer insights into your health and longevity. We go throug...
Oct 29, 2024•32 min•Ep. 178
Ever wondered what it takes to turn a personal health crisis into a powerful media career? Join us as we chat with Charles Mattocks, a dynamic television and movie producer, whose journey from acting and music to advocating for health education is nothing short of inspiring. Inspired by his legendary uncle Bob Marley, Charles shares how his type 2 diabetes diagnosis led him to create impactful documentaries and TV series like "Reverse," which ambitiously tackles the mental, physical, and spiritu...
Oct 22, 2024•33 min•Ep. 177
This week we uncover the secret to a longer, healthier life as we sit down with Dr Buck Joffrey, a former neurosurgery and otolaryngology resident turned cosmetic surgeon and serial entrepreneur. Buck’s journey from the operating room to the forefront of longevity science was ignited by a personal health scare and fueled by the pioneering work of David Sinclair. Join us as Buck shares his transformative story, emphasizing the profound impact of lifestyle changes like diet, exercise, and sleep on...
Oct 15, 2024•44 min•Ep. 176
Imagine a world where aging is optional and mental decline is not a foregone conclusion. Tune in to our fascinating episode as we sit down with the great Greta Blackburn and her panel of experts that I had the privilege of being part of at the recent RAADFEST conference in Anaheim, California. The group included Dr Vince Giampapa, Dr Shelly Jordan, and Dr Stephen Sideroff. We got to explore groundbreaking strategies for mental health and longevity. From personal stories of resilience to cutting-...
Oct 08, 2024•1 hr 5 min
Discover how GLP-1 agonists are revolutionizing weight loss and health management as we sit down with Dr Amer Sayed, a cardiologist and an inspiring figure who has faced his own battles with obesity. Inspired by a peptide found in lizards, these medications offer a new hope for individuals struggling with weight despite leading active lifestyles. Amir's firsthand experience and professional insights reveal how these game-changing drugs can help suppress appetite, reduce gastrointestinal motility...
Oct 01, 2024•39 min•Ep. 174
It is with great sadness that I share that my friend and colleague Dr. Alan Green, the leading pioneer in the off-label use of rapamycin with the hope of improving health and longevity, has passed away. His brilliant work has transformed the lives of many of us who will remember him and continue to benefit from his wisdom for many years to come. He has truly left the world a better place. This week will be a rebroadcast a conversation that I had with him in 2021. We discuss his personal health j...
Sep 24, 2024•1 hr 7 min•Ep. 173
Discover the secrets to lasting health and well-being with our guest, David Medansky, as he shares his awe-inspiring transformation from being overweight to conquering Mount Kilimanjaro at the age of 67. After a dire warning from his doctor about a potential fatal heart attack, David didn't just lose 50 pounds—he embraced a healthier lifestyle that has kept him thriving. Tune in to learn why he believes lifestyle changes far outweigh temporary diets and how pure water—distilled, high-quality spr...
Sep 17, 2024•31 min•Ep. 172
Can rapamycin be the key to unlocking a longer, healthier life? Join us as Krister Kauppi, a dedicated health and longevity enthusiast, shares his captivating journey from a personal health scare to discovering the potential of rapamycin as an alternative to intermittent fasting. We delve into the science behind this intriguing compound, focusing on how it inhibits mTOR and activates catabolic processes, potentially slowing down aging and reducing the incidence of age-related diseases. Together,...
Sep 10, 2024•39 min
This week we explore the secrets of our DNA and take control of our health destiny as we join Dahlia Attia-King, the innovative CEO of Panacea, as we examine the transformative potential of clinical-grade gene sequencing. We delve into how this technology eclipses the consumer-grade genotyping you might know from popular companies like 23andMe, offering a more comprehensive analysis with the power to revolutionize disease prevention and personalized health strategies. Dahlia's insights into the ...
Sep 03, 2024•40 min•Ep. 170
