How do you make a diagnosis of erythrocytosis? Is full blood count enough or do you need more specific tests? How is the classification in primary and secondary erythrocytosis linked to EPO levels? Is idiopathic erythrocytosis really a vanishing entity? These are some of the questions Prof Mary-Frances McCullin answers in this podcast, giving listeners the key information necessary to understand erythrocytosis in clinical practice. Host: Prof Shaun McCann; Guest: Prof Mary-Frances McMullin What ...
May 20, 2022•18 min•Ep. 44
In the seventh and final episode of the Clinical Trial podcast series, you can hear Prof. Konstanze Döhner and Prof. Antonio Almeida exchanging ideas and thought-provoking opinions about how investigator-initiated clinical trials and new trial designs can provide patients early access to novel drugs. They discuss the importance of large collaborative groups, the complexity of current requirements that must be in place, and the impact that these challenges may have, along with the relevant issues...
May 16, 2022•46 min•Ep. 43
This series of two podcasts leads you on a journey through the main clinical and therapeutical aspects of Cutaneous T Cell Lymphomas (CTCLs), a heterogeneous group of lymphoid neoplasms characterized by primary cutaneous localization. Albeit rare, CTCLs have peculiar clinical characteristics, requiring a multidisciplinary approach and a strict collaboration between different specialists, allowing for a timely and precise diagnosis, critical for the good outcome of these patients. Join dermatolog...
May 13, 2022•22 min•Ep. 41
This series of two podcasts leads you on a journey through the main clinical and therapeutical aspects of Cutaneous T Cell Lymphomas (CTCLs), a heterogeneous group of lymphoid neoplasms characterized by primary cutaneous localization. Albeit rare, CTCLs have peculiar clinical characteristics, requiring a multidisciplinary approach and a strict collaboration between different specialists, allowing for a timely and precise diagnosis, critical for the good outcome of these patients. Join dermatolog...
May 13, 2022•26 min•Ep. 42
Dr David Kurtz discusses in this podcast the most recent technical developments and practical applications of circulating tumor DNA and liquid biopsies, an active area of research in the last 25 years, which is now gaining more importance and translational application in the clinic. In tumors like B-cell non-Hodgkin lymphomas, for example, somatic mutations can now be tracked and diagnosed using these techniques. Other fields of active investigations include CLL and solid tumors, as well as dise...
Apr 08, 2022•16 min•Season 1Ep. 40
The whole world of CML changed in the early 2000s with the introduction of imatinib and TKIs, however, the situation in developing countries can be significantly different from Europe and USA, as discussed by Prof Hemant Malhotra in this podcast. Short-backs may encompass the molecular diagnosis and monitoring of the disease (not everywhere available) as well as the cost of drugs and medical expense coverage. On the other hand, the relative affordability of generic TKIs may cause skipping of exp...
Apr 01, 2022•14 min•Season 1Ep. 39
Transfusion processes have changed significantly in recent years, at the same time changing the guidelines for blood cell replacement therapy. Listen to Prof. Michael Murphy in this podcast as he provides an overview of the most up-to-date topics in transfusion, including the relevant risk of over-transfusion, restricted transfusion practices, and also the issues of delayed transfusion and transfusion-related infections. "Don't give two when one will do," should remain the bottom line criterion ...
Mar 25, 2022•15 min•Season 1Ep. 38
This podcast follows a short discussion between two young hematologists on a clinical case review of a chronic myeloid leukemia patient called Naomi. In this discussion, the hematologists go through Naomi’s case while addressing the management of CML patients in complete molecular response and the requirements for discontinuation of tyrosine kinase treatment in CML patients. This podcast is rendered from QR Case 5 - Chronic Myeloid Leukemia (Naomi) on the EHA Campus. What did you think of this p...
Mar 04, 2022•7 min•Season 1Ep. 37
In the sixth episode of the Clinical Trial podcast series, Prof. Robert Hills discusses the different reasons that lead to the end of a trial – especially when it is earlier than planned. He also gives us a summary of what happens after the trial; the importance of some steps involving the data and their availability, and the writing of reports for the appropriate regulatory authorities. In this series of Clinical Trial podcasts produced by EHA, experts unravel for you the many issues linked to ...
Feb 22, 2022•22 min•Season 1Ep. 36
In the fourth episode of the EHA Diagnosing And Treating Iron Deficiency podcast series, host Prof Gunnar Birgegård and guest expert Prof Antonio Almeda discuss the diagnostic and therapeutic management of iron deficiency and anemia in the perioperative setting, a clinical situation where having inadequate iron stores carries significant clinical consequences on mortality and morbidity outcomes. They also address the conclusions of different studies that have investigated the impact of repleting...
Feb 18, 2022•28 min•Season 1Ep. 35
In the fifth episode of the Clinical Trial podcast series, Prof. Robert Hills discusses the documentation of clinical trials and how it represents a safeguard for the credibility of the trial. He points out the importance of finding a good balance between too many documents and not enough of them. In addition, he highlights the multitude of different groups working on a clinical trial, which ultimately renders documentation an insurance to a smooth process. In this series of Clinical Trial podca...
Feb 15, 2022•20 min•Season 1Ep. 34
In the fifth and final episode of the Aging Patient: Dispelling Myths podcast series, host Gareth Tucker and guest experts Prof Raul Cordoba, Dr Ulrich Wedding, and Dr Dominique Bron discuss the ethical issues associated with treating hematological malignancies in older adults. They raise different points regarding treatment decisions made with (and not without) the patient and amongst other parameters, how much of an impact costs have in the choice of treatment. Dr Bron also reminds us of the 4...
Feb 11, 2022•38 min•Season 1Ep. 33
In the fourth episode of the Clinical Trial podcasts, Dr. Eleftheria Hatzimichael gives us an overview of the sponsor's role and responsibilities in investigator-initiated clinical trials. The different meaning of "sponsor" and "funder", the importance for physicians to be involved in the design of clinical trials, the eight overarching responsibilities of the sponsor, are all key topics discussed in this podcast. In this series of Clinical Trial podcasts produced by EHA, experts unravel for you...
Feb 08, 2022•17 min•Season 1Ep. 32
In the fourth episode of the Aging Patient: Dispelling Myths podcast series, host Gareth Tucker and guest expert Prof Monica Engelhardt discuss how comprehensive geriatric assessment can guide treatment decisions and improve patient outcomes. Dr Engelhardt gives us an insight into her clinical practice and how elderly hematology patients are receptive - or not - to this testing. You will also learn what are the parameters to consider when treating elderly patients for hematologic malignancies, e...
Feb 04, 2022•34 min•Season 1Ep. 31
In the third episode of the Clinical Trial podcasts, Prof. Martin Dreyling from the University of Munich makes several points about standards of care in clinical studies, also mentioned as GCPs (Good Clinical Practices). He gives us a historical perspective on the establishment of these standards 20 years ago, and how they need an update through what he calls a ‘reality check’. Prof. Dreyling is part of the coalition Reducing Bureaucracy in Clinical Trials and explains what they are proposing to...
Feb 01, 2022•17 min•Season 1Ep. 30
In the third episode of the Aging Patient: Dispelling Myths podcast series, host Gareth Tucker and experts Prof Antonio Almeida, Prof Valentin Goede, and Dr Annamaria Brioli discuss the treatment of hematological malignancies in older adults, involving polypharmacy in most cases. They describe how patients commonly react to polypharmacy and how challenging it can be to have all the information about a patient’s full list of medication, and to keep them compliant. They also address the step of de...
Jan 28, 2022•32 min•Season 1Ep. 29
In the second episode of the Clinical Trial podcasts, former EHA President Prof. John Gribben gives us an overview of the role(s) of CROs (Contract Research Organizations) in clinical investigation. He discusses how they can help, notably with the paper trails associated with clinical trials, and how they should be constructive partners in the process of clinical research. In this series of Clinical Trial podcasts produced by EHA, experts unravel for you the many issues linked to the design and ...
Jan 25, 2022•18 min•Season 1Ep. 28
In the second episode of the Aging Patient: Dispelling Myths podcast series, host Gareth Tucker discusses with experts Prof Alessandra Tucci and Prof Sergio Storti the definition and importance of patient assessment (including frailty, comorbidity, and polypharmacy), in older adults with hematological conditions and how it can be used to determine the overall ‘fitness’ of a patient. They also discuss the critical role of interactions between HCPs, patients, and their entourage in the assessment....
Jan 21, 2022•31 min•Season 1Ep. 27
In this podcast, the last of a series dedicated to Multiple Myeloma in underserved patient populations with, Prof Sonja Zweegman focuses on the challenges associated with MM treatment in older patients, namely the assessment of frailty and how to adapt treatment in this population. The podcast also addresses the specific characteristics of MM in the elderly, including the incidence of genetic mutations and the role of comorbidities. Speaker: Prof Sonja Zweegman; Host: Prof Pieter Sonneveld...
Jan 20, 2022•23 min•Season 1Ep. 26
In the first episode of the Clinical Trial podcasts, Amsterdam UMC researcher and author of “A Quick Guide on How to Conduct Medical Research” Dr. Marieke Ter Wee points out the importance of formulating a research question at the beginning of any clinical trial. What models are used to formulate the question and answer to it? She unravels the main parts of a research proposal that should be elaborated by the authors of clinical studies. In this series of Clinical Trial podcasts produced by EHA,...
Jan 18, 2022•18 min•Season 1Ep. 25
In the Aging Patient: Dispelling Myths podcast series, Prof Raul Cordoba kicks off a series of podcasts that will offer you up-to-date information about hematology in older adults. For the first interview, he welcomes guest expert Dr Kristina Kirschner to discuss aging and clonal disease. You will learn how clonal hematopoiesis increases with advancing age and how the accumulation of some clonal mutations have been linked with hematological cancers. Dr Kirschner answers questions - asked b...
Jan 14, 2022•20 min•Season 1Ep. 24
In the third episode of the Iron Deficiency podcast series, host Prof Gunnar Birgegård and guest expert Dr Noemi Roy review the many important functions iron plays in the body, providing the background for the high prevalence of iron deficiency in women, particularly in their fertile life and during pregnancies. They address different strategies of treatment, including IV, oral treatment, and nutrition recommendations. Finally, they also highlight the importance of treating iron deficiency after...
Dec 31, 2021•40 min•Season 1Ep. 23
In the second episode of the EHA Diagnosing And Treating Iron Deficiency podcast series, host Prof Gunnar Birgegård and guest expert Prof Christopher Winearls highlight the high prevalence of iron deficiency anemia in patients with CKD, together with its association with poor long-term outcomes. They discuss the importance of monitoring iron on top of monitoring erythropoietin and treating the deficiency prior to the use of erythropoietin. Overall, Prof Winearls discloses how to evaluate ferriti...
Dec 24, 2021•30 min•Season 1Ep. 22
In the first episode of the EHA Diagnosing And Treating Iron Deficiency podcast series, Prof Gunnar Birgegård and host expert Prof Antonio Almeida define what is iron deficiency and more precisely functional iron deficiency. They discuss the prevalence of anemia in cardiac failure patients and the relation between severity of the heart disease and incidence of iron deficiency. They also highlight the importance of monitoring potential renal symptoms for better treatment outcomes. Host: Prof Gunn...
Dec 17, 2021•32 min•Season 1Ep. 21
In episode 9 of "EHA Unplugged", Prof. Shaun McCann describes the importance of general medical management in multiple myeloma (MM) patients and the application of the principles of treatment in different subpopulations of patients. He also explains how to diagnose MM and assess the response to treatment. What did you think of this podcast? Share your opinions with us in this short feedback survey. Provide Feedback Would you like to receive EBAH CME credit points for listening to this podcast? P...
Dec 10, 2021•24 min•Season 1Ep. 20
This podcast, the second of a series dedicated to Multiple Myeloma in underserved populations, addresses clinical challenges in MM, with a focus on high-risk disease and cytogenetics. Prof Weisel describes the established genetic prognostic markers in MM, and the new abnormalities that are becoming important, besides the role and impact of Minimal Residual Disease (MRD) on risk status and classification of MM patients. Speaker: Prof Katja Weisel; Host: Prof Pieter Sonneveld What did you think of...
Dec 07, 2021•29 min•Season 1Ep. 19
In episode 8 of "EHA Unplugged", Prof. Shaun McCann details the diagnostic and prognostic criteria of CLL and the correct diagnostic work-up. He also describes the increasing array of treatments available for CLL patients and outlines the role of allogeneic transplantation in this disease. What did you think of this podcast? Share your opinions with us in this short feedback survey. Provide Feedback Would you like to receive EBAH CME credit points for listening to this podcast? Please visit the ...
Dec 03, 2021•27 min•Season 1Ep. 18
In episode 7 of "EHA Unplugged", Prof. Shaun McCann describes the clinical and genetic features of chronic myeloid leukemia (CML), discusses the best therapeutic options, and characterizes the changes that occur in the natural history of the disease after the introduction of tyrosine-kinase inhibitors (TKIs). What did you think of this podcast? Share your opinions with us in this short feedback survey. Provide Feedback Would you like to receive EBAH CME credit points for listening to this podcas...
Nov 26, 2021•28 min•Season 1Ep. 17
This podcast series brings together people affected by SCD and specialist hematologists to shed light on this widely misunderstood condition, bringing the guidelines to life and helping healthcare professionals improve their practice by understanding the patient experience. In this closing discussion, Dr Jo Howard and Professor Léon Tshilolo reflect on what they have learned from their conversations with people affected by sickle cell disease and sickle cell trait, and discuss the present and fu...
Nov 16, 2021•32 min•Season 1Ep. 16
In this podcast, the first of a series dedicated to Multiple Myeloma in underserved patient populations, Prof Terpos illustrates the impact of renal disease on MM outcomes and how it should best be managed. Follow the podcast to learn about assessment and monitoring of renal function in MM patients, the available treatment options for this population, and the role and outcomes of kidney transplantation. Speaker: Prof Evangelos Terpos; Host: Prof Pieter Sonneveld What did you think of this podcas...
Nov 15, 2021•1 hr 7 min•Season 1Ep. 15
