In this episode, we discuss the evidence behind the choice of adrenaline vs noradrenaline in patients who achieved ROSC (return of spontaneous circulation) after OHCA(out of hospital cardiac arrest).
In this episode, we discuss the controversy surrounding the use of NIV in hypoxemic respiratory failure in severe COVID-19. The results of the RECOVERY-RS trial has provided us with significant evidence on this topic.
In this episode, we discuss the recently published trial on long term outcomes in COVID patients.
In this episode, we discuss a recently published PLUS study comparing saline solution with Plasmalyte-148. This study demonstrated no significant mortality difference between the saline group and the plasmalyte-148 group.
In this episode, we discuss the recently published RCT evaluating the role of extended thromboprophylaxis in COVID-19.
In this episode, we discuss the challenges faced by healthcare systems and the patterns emerging from the current COVID-19 pandemic wave caused by the Omicron variant.
In this episode, we discuss a recently published trial comparing conventional oxygen therapy and high flow nasal oxygen therapy.
In this podcast, we discuss the controversy surrounding glycemic control in intensive care. We discuss the target range, the ideal amount of time spent in the target range and the utility of continuous glycemic monitoring in critically ill patients.
In this episode, we discuss the CONTROLLING study which compared the novel strategy of individualised glycemic control vs conventional glucose control.
In this episode, we dive deeper into the controversy around the timing of initiation of RRT in Intensive Care.
The controversy around the dose of steroid dose in COVID-19 still exists. In this podcast, we discuss the recently published RCT COVID Steroid 2 and dive deeper into this controversy.
In this episode, we discuss some of the key recommendations and the rationale behind them from recently published SSCG 2021.
Hyperventilation has been used to control raised ICP for decades. However, the evidence behind it is very weak. In this podcast, we discuss the recently published study by CENTRE-TBI to address this controversy.
In this episode, we discuss the evidence behind the dogmatic practice of routinely using ICP monitoring in patients with traumatic brain injury admitted to ICU.
The debate over low vs high oxygenation targets continue. In this podcast, we discuss the recently published trial in JAMA which evaluates the effect of high oxygenation on organ failure scores.
In this episode, we discuss the controversies around the long term sequelae of COVID-19. We dive deeper into the available evidence and suggest the next steps to address this very significant issue.
In this podcast, we discuss another landmark study called BASIC, which evaluated the superiority of balanced salt solution over 0.9% saline in critically ill patients admitted to Brazilian intensive care units.
The evidence for the use of Remdesivir in COVID-19 is conflicting. Different guidelines have suggested contradictory recommendations on its use in COVID-19. Tocilizumab, although demonstrated mortality benefit in conjunction with steroids, we do not have data on its long term outcomes including quality of life. In this episode, we revisit the controversy surrounding the use of these agents in COVID-19.
No standard protocol exists to decrease or eliminate preoperative fasting times for adult ICU patients with cuffed endotracheal tubes; however, multiple intensive care units across the globe have implemented their own protocols with adjusted times for the intubated patient. This has led to significant variability in practices along with potential harm to ICU patients. In this podcast, we challenge this another dogmatic practice in the Intensive care unit and dive deeper into available evidence....
In this episode, we talk about the novel concept called mechanical power in ventilating patients with ARDS. This concept has led to a new debate as to whether we should move away from the dogmatic approach of fixed tidal volume ventilation to an individualised ventilation strategy for patients with ARDS.
In this episode, we discuss the recently published landmark RCT -TTM2. This trial has answered the important question and forced us to reconsider our management practices around post-out of hospital cardiac arrest management.
The recent study published by Golligher et al have challenged the dogma of setting 6-8 ml/kg Vt for all patients with ARDS. In this study, the authors demonstrated that the mortality in ARDS is related to driving pressure and baseline elastance and there is no correlation between mortality and plateau pressure or P/F ratio. In this episode, we discuss how this study will impact the future of mechanical ventilation in ARDS.
Oxygen is a precious commodity. COVID-19 pandemic has reminded us of the significance of Oxygen and we need to be mindful that Oxygen is a drug. It has its own side effects and thus warrants cautious use. In this podcast, we discuss controversial but thought-provoking COAST trial in-depth.
COVID-19 pandemic continues to be a major problem across the globe. Various treatment options are emerging and we are desperate to achieve some normalcy in our lives. The recent addition is the use of monoclonal antibodies, which constitute a form of passive immunotherapy. In this podcast, we dive deeper into the available evidence on this novel treatment option.
Recently published RCTs and various guidelines have given us conflicting results w.r.t optimal dose of thromboprophylaxis in patients with COVID-19. In this episode, we dive deeper into the available evidence on this topic and suggest the rational approach in selecting the dose of thromboprophylaxis in COVID-19 patients.
Different Vaccines were developed during the COVID-19 pandemic at unprecedented speed using different platforms. However, recent reports raised concerns regarding thrombotic complications and thrombocytopenia after certain vaccines. In this episode, we discuss the pathophysiology and the treatment of this newly described syndrome.
In this episode, we discuss another landmark trial that has answered the very relevant question regarding the use of anti-fibrinolytic treatment in subarachnoid hemorrhage.
The use of neuromuscular blockade is not uncommon however, it's associated with many complications such as the increased risk of ICU acquired weakness, prolonged length of ICU stay along with the increased risk of corneal ulceration and VTE. In this episode, we discuss various indications for the use of NMB agents in ICU and review the available evidence on this topic.
Restrictive Vs Liberal transfusion strategy debate has come to the surface after the publication of the REALITY trial. In this podcast, we dive deeper into proposed transfusion thresholds in intensive care in various subgroups and the evidence behind them.
Hemoglobin targets in patients with myocardial infarction are still debatable. In this episode, we discuss the landmark REALITY trial, which explores the non-inferiority of a restrictive transfusion strategy over a liberal transfusion strategy.
