Join Ryan K. Shields, PharmD, MS, in the third of 3 podcasts from our live event, “The Plot (and Sputum) Thickens: Encountering Carbapenem Resistance in Critically Ill Patients” to learn how to optimize antimicrobial regimens and develop evidence-based antibiotic management plans for complex infections caused by carbapenem-resistant bacteria. Topics covered in this segment include: Mechanisms of resistance in S. maltophilia Current frontline therapies 2024 IDSA guidance for treatment Presenter: ...
Nov 25, 2025•9 min•Ep. 479
Join Marin H. Kollef, MD in the first of 3 podcasts from our live event, “The Plot (and Sputum) Thickens: Encountering Carbapenem Resistance in Critically Ill Patients” to learn how to optimize antimicrobial regimens and develop evidence-based antibiotic management plans for complex infections caused by carbapenem-resistant bacteria. Topics covered in this segment include Antimicrobial resistance mechanisms Diagnostic strategies for identifying resistance Antibiotic selection strategies Preferre...
Nov 25, 2025•15 min•Ep. 478
Join Ryan K. Shields, PharmD, MS, in the second of three recap podcasts taken from our live event, “The Plot (and Sputum) Thickens: Encountering Carbapenem Resistance in Critically Ill Patients.” Learn how to optimize antimicrobial regimens and develop evidence-based antibiotic management plans for complex infections caused by carbapenem-resistant bacteria. Topics covered in this segment include: The diverse mechanisms of β-lactam resistance The effect of resistance mechanisms on susceptibility ...
Nov 25, 2025•19 min•Ep. 477
Fear of virologic failure is a major barrier to ensuring that people living with virally suppressed HIV are receiving the most optimal antiretroviral therapy (ART) regimen for them. Stream this Medical Minute to learn more about key guideline recommendations regarding ART switch and reassuring clinical data regarding efficacy, tolerability, and quality of life associated with switching a suppressive ART regimen. Topics covered include: Efficacy of switching to 2-drug oral ART: real-world evidenc...
Nov 21, 2025•19 min•Ep. 475
Unnecessary broad-spectrum antibiotics can drive antimicrobial resistance and cause adverse events, whereas inadequate antibiotic coverage is linked to increased mortality and length of stay for patients with bloodstream infections (BSIs). Listen now to learn from Jose Alexander, MD, D(ABMM), CIC, FCCM, SM/MB(ASCP), how to use rapid genotypic and phenotypic antimicrobial susceptibility testing results to inform antibiotic selection for patients with gram-negative BSIs. Topics covered include: Ty...
Nov 18, 2025•18 min•Ep. 473
Rapid phenotypic antimicrobial susceptibility testing (AST) significantly reduces time to actionable results and can improve antibiotic decision-making for patients with bloodstream infections. Listen in to learn from Michael P. Veve, PharmD, MPH, how to optimally integrate rapid phenotypic AST into clinical practice, including incorporation into your existing antimicrobial stewardship workflow. Topics covered include: Considerations for implementation Decision-making steps for implementation Th...
Nov 18, 2025•28 min•Ep. 474
Sepsis and bloodstream infections (BSIs) are common and cause millions of deaths each year, with a disproportionate burden in low-income and middle-income countries. Tune in to learn from Jasmine R. Marcelin, MD, FACP, FIDSA, how inadequate antibiotic coverage can be linked to increased mortality and length of stay and how unnecessary broad-spectrum antibiotics can drive antimicrobial resistance. Topics covered include: The worldwide burden of sepsis and BSIs The ongoing threat of antimicrobial ...
Nov 18, 2025•19 min•Ep. 471
Stream this podcast to learn from experts Tessa Rife-Pennington, PharmD, BCGP, and Frank North, PharmD, MPA, DPLA, DASPL, how specialty pharmacists can apply practical strategies within different pharmacy settings to overcome barriers to PrEP use, especially among underserved patient subpopulations. Topics covered include: PrEP candidacy Selection of individualized regimens Key barriers to PrEP use Strategies for overcoming key barriers to PrEP access Evolving state-based legislation on PrEP pro...
Nov 11, 2025•45 min•Ep. 470
In this episode, expert patient navigators Shellye Jones and Lauren Jackson discuss the key take-home points of our online educational program on facilitating engagement in HIV care and propose a framework for effectively retaining people in care. Topics covered include: How to approach a patient with complex barriers to engagement in healthcare Resources for staying in care, such as wraparound services Setting SMART goals and formulating action plans with patients Deconstructing stigma and impl...
Oct 21, 2025•24 min•Ep. 469
Don’t settle! Listen in to learn how a proactive approach to ART switch can improve treatment satisfaction and quality of life for people living with virologically suppressed HIV. Topics covered include: International AIDS Society (IAS) USA and European AIDS Clinical Society (EACS) Guidance on Switching ART With Viral Suppression Considerations for switching to a 2-drug regimen or long-acting ART Methods for assessing patient satisfaction with their current ART regimen Presenters: Monica Gandhi,...
Oct 16, 2025•24 min•Ep. 468
Detectable HIV-1 RNA (viral load) can seem very worrisome for people living with HIV who are receiving antiretroviral therapy (ART) and for their healthcare professionals. Tune in to learn how Brian R. Wood, MD, differentiates HIV-1 RNA “blips” from persistent low-level viremia and from virologic failure, and how he handles each scenario. Presenter : Brian R. Wood, MD Professor of Medicine Division of Allergy and Infectious Diseases University of Washington Seattle, Washington Link to full progr...
Oct 08, 2025•26 min•Ep. 467
Tune into this podcast from Dr Clíona Ní Cheallaigh to learn how to provide person-centered care for treatment-experienced people with HIV. Gain strategies to address each individual’s specific history and needs while considering the potential impact of comorbidities and other health challenges. Topics covered include: Individualizing Antiretroviral Regimens for Treatment-Experienced People With HIV Strategies to Improve Adherence and Addressing Barriers to Engagement in Care Person-Centered, Tr...
Sep 26, 2025•16 min•Ep. 466
In this podcast, expert faculty Atul Humar, MD, FRCP (C), and Camille Kotton, MD, FIDSA, FAST, take a deep dive into complex clinical scenarios and explore designing antiviral regimens for refractory CMV infections to minimize antiviral toxicities and maximize efficacy. Topics covered include: Management for suspected drug-resistant CMV infection Illustrative patient cases Gene mutations in CMV Presenters: Atul Humar, MD, FRCPC, FAST Professor Department of Medicine University of Toronto Eaton F...
Sep 03, 2025•17 min•Ep. 465
Tune in to learn the fundamentals for timely identification of refractory cytomegalovirus (CMV) infections following solid organ transplantation from expert faculty, Camille Kotton, MD, FIDSA, FAST. Topics covered include: Direct and indirect effects of CMV infection Risk factors for resistant/refractory CMV Defining resistant/refractory CMV Presenter: Camille Kotton, MD, FIDSA, FAST Clinical Director, Transplant and Immunocompromised Host Infectious Diseases Infectious Diseases Division Mass Ge...
Aug 29, 2025•12 min•Ep. 463
Learn to appropriately modify antiviral therapy in solid organ transplant recipients with treatment-refractory cytomegalovirus (CMV) infections with expert faculty, Atul Humar, MD, FRCP (C). Topics covered include: Comparisons of available CMV antiviral therapies: Ganciclovir, valganciclovir, foscarnet, cidofovir, maribavir Considerations for renal function monitoring with ganciclovir and valganciclovir A treatment algorithm for relapsed/refractory CMV The latest clinical trial data and guidelin...
Aug 29, 2025•19 min•Ep. 464
Listen in as Dr Marcus Pereira and Dr Raymund R. Razonable explore strategies for individualization of CMV management in high-risk kidney transplant recipients. Topics include: Risk factors and prevention of late-onset CMV disease Early detection of late CMV infection CMV cell-mediated immunity monitoring Primary and secondary prophylaxis Presenters: Marcus Pereira, MD, MPH, FAST Associate Professor of Medicine Director of Clinical Services, Division of Infectious Diseases Medical Director, Tran...
Aug 26, 2025•25 min•Ep. 461
Listen in as Dr Marcus Pereira and Dr Raymund R. Razonable discuss the fundamentals of cytomegalovirus (CMV) in kidney transplant recipients. Topics include: CMV pathogenesis Direct and indirect effects of CMV infection Overview of patient risk factors CMV risk based on serologic status Presenters: Marcus Pereira, MD, MPH, FAST Associate Professor of Medicine Director of Clinical Services, Division of Infectious Diseases Medical Director, Transplant Infectious Disease Program Columbia University...
Aug 26, 2025•13 min•Ep. 460
Listen in as Dr Trevor Van Schooneveld explores rapid syndromic testing for gastrointestinal and joint infections and discusses how to apply best practices for diagnostic and antimicrobial stewardship in syndromic testing. Topics covered include: Who should be tested for infectious diarrhea Types of gastrointestinal syndromic panels Types of syndromic panels for joint infections Real-world applications for joint syndromic panels Presenters : Trevor Van Schooneveld, MD Professor, Division of Infe...
Aug 26, 2025•21 min•Ep. 462
Listen in as Dr Marcus Pereira discusses how to design cytomegalovirus (CMV) antiviral regimens for high-risk kidney transplant recipients to mitigate the impact of infection while minimizing drug toxicities. Topics include: Strategies for CMV prevention: prophylaxis, preemptive therapy, and hybrid methods Characteristics of available antiviral drugs Monitoring considerations for antivirals Presenters : Marcus Pereira, MD, MPH, FAST Associate Professor of Medicine Director of Clinical Services, ...
Aug 26, 2025•11 min•Ep. 458
Join Alicia Stillman of the American Society for Meningitis Prevention, as she shares a very personal story of loss that might change how you view meningitis vaccination. Presenter: Alicia Stillman, MBA, MPH Patient Advocate Co-Executive Director, American Society for Meningitis Prevention Executive Director, Emily Stillman Foundation Detroit, Michigan Link to full program: https://bit.ly/4mYvTXQ Register for the practical symposium: https://bit.ly/4mUOsvV Get access to all of our new podcasts b...
Aug 25, 2025•7 min•Ep. 459
Listen in as Michael Satlin, MD, MS, FIDSA,explores rapid syndromic testing for bloodstream infections and discusses how to apply best practices for diagnostic and antimicrobial stewardship in syndromic testing. Topics covered include: Types of upper and lower respiratory infection panels Considerations for when to use respiratory syndromic testing How to use syndromic testing to guide both therapy escalation and de-escalation How syndromic testing fits in with traditional testing methods, such ...
Aug 19, 2025•25 min•Ep. 457
Stream this podcast to learn from experts Alexis E. Horace, PharmD, BCACP , andNimish Patel, PharmD, PhD, AAHIVP, how specialist pharmacists can overcome key barriers to care and apply best practices for optimization of antiretroviral therapy for HIV. Topics covered include: Leveraging pharmacists’ expertise to advance HIV treatment Pharmacist roles in HIV care and management The current ART landscape Regimen simplification Consideration of patient preferences, health factors, and comorbidities ...
Aug 18, 2025•44 min•Ep. 456
Tune in to learn how the recent FDA approval of lenacapavir (LEN) for PreP integrates into the current field of HIV prevention. Listen on the go or follow along with our expert-curated slides . Topics covered include: The current landscape of PrEP FDA approval of lenacapavir Phase III efficacy and safety data for lenacapavir Recommendations and perspectives on the future of PrEP Presenters: Colleen F. Kelley, MD, MPH Professor of Medicine Division of Infectious Diseases Department of Medicine Co...
Aug 13, 2025•33 min•Ep. 455
Hear from experts in HIV care Beatriz Grinsztejn, MD, PhD, and Rosie Mnggibisa, MBChB, MPH, as they discuss their insights on some of the most clinically relevant new data presented at IAS 2025, including studies on: Gaps in care for adolescents and young adults living with HIV Global impact of funding cuts Antiretroviral therapy for treating HIV Patient management strategies for people living with HIV and obesity Presenters: Beatriz Grinsztejn, MD, PhD Director STI/HIV Clinical Research Laborat...
Aug 12, 2025•44 min•Ep. 454
Listen in as Dr Emily Heil explores rapid syndromic testing for bloodstream infections and discusses how to apply best practices for diagnostic and antimicrobial stewardship in syndromic testing. Topics covered include: The importance of good blood culture practices and finding the balance between overuse and underuse Blood culture improvement programs The utility of rapid diagnostic tests Resistance markers for earlier targeted therapy Presenters : Emily Heil, PharmD, MS, BCIDP, AAHIVP Professo...
Aug 12, 2025•19 min•Ep. 453
Tune in as Dr George Behrenspresents the fundamentals on specialized agents for treatment-experienced people living with HIV. Topics covered include: Key targets and mechanisms of action for specialized HIV drugs Clinical trial data supporting safety and efficacy of these agents Considerations for potential drug–drug interactions Strategies for leveraging these agents to construct new ART regimens for treatment-experienced individuals Presenters: Georg Behrens, MD Professor of Immunology Senior ...
Aug 11, 2025•23 min•Ep. 452
In this episode, Dr Josep M. Llibrereviews the essentials on ART selection for treatment-experienced people with HIV and comorbidities. Topics covered include: Underlying reasons for development of multidrug-resistant HIV Inflammation and immune activation associated with frequency of age-related conditions General principles for designing ART regimens for persons with multidrug-resistant HIV Treatment options for highly treatment‒experienced people Considerations for comorbidities and drug–drug...
Aug 08, 2025•23 min•Ep. 451
Tune in as Dr Daniel R. Kuritzkes presents a quick and easy primer on managing multidrug resistant HIV. Topics covered include: How to recognize key populations who may present with multidrug-resistant HIV Identifying underlying reasons for regimen failure Evaluating resistance profiles Constructing new ART regimens for treatment-experienced individuals. Presenters: Daniel R. Kuritzkes, MD Chief, Division of Infectious Diseases Brigham and Women's Hospital Harriet Ryan Albee Professor of Medicin...
Aug 05, 2025•10 min•Ep. 450
In this episode, Palak J. Trivedi, BSc, MBBS, PhD, MRCP, ESEGH, discusses the most recent developments in primary biliary cholangitis (PBC) treatment, including cutting-edge data on new and emerging agents and how these updates may be integrated into your practice. Topics include: Steatotic liver disease and PBC Vibration-controlled transient elastography (VCTE) and discordant biochemical responses in PBC PPAR agonists and IBATs for PBC treatment Presenter: Palak J. Trivedi, BSc, MBBS, PhD, MRC...
Jul 07, 2025•19 min•Ep. 448
Listen as expert faculty answer your most pressing questions on optimizing immunization in clinical practice. Topics covered include: Practical methods for improving confidence in vaccines How to educate patients on vaccine development and safety monitoring Effective strategies to tailor recommendations, such as motivational interviewing Ways to navigate clinical encounters and address vaccine hesitancy Presenters: Robert H. Hopkins, Jr., MD, MACP Professor of Internal Medicine and Pediatrics Un...
Jun 30, 2025•36 min•Ep. 447