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a16z Podcast

Andreessen Horowitza16z.simplecast.com
The a16z Podcast discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This podcast is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!

Episodes

a16z Podcast: How Founders Hire a VP of Product

Hiring a VP of Product -- especially as the founder of the company -- can almost feel like handing over your baby to someone else to hold, observes a16z executive talent team partner Caroline Horn, who hosted an event on this topic earlier this year (which this podcast is based on). Featuring Vijay Balasubramaniyan, founder/CEO of Pindrop; Shishir Mehrotra, founder and CEO of Coda; Gokul Rajaram, Production Engineering Lead at Square; and Alan Schaaf, founder/CEO of Imgur -- and moderated by gen...

Nov 10, 201730 minEp. 337

a16z Podcast: Putting AI in Medicine, in Practice

with Brandon Ballinger (@bballinger), Mintu Turakhia (@leftbundle), Vijay Pande (@vijaypande), and Hanne Tidnam (@omnivorousread) There’s been a lot of talk about technology -- and AI, deep learning, and machine learning specifically -- finally reaching the healthcare sector. But AI in medicine isn’t actually new; it’s actually been there since the 1960s. And yet we didn’t see it effect a true change, or even become a real part our doctor’s offices -- let alone routine healthcare services. So: w...

Nov 03, 201730 minEp. 336

a16z Podcast: The Why Behind the Weird

Author and professor at George Mason University, Peter Leeson describes himself as not just an economist but as a "collector of curiosa." In his latest book, WTF?! An Economic Tour of the Weird, Leeson looks at just that -- the strangest beliefs, superstitions and rituals humankind has engaged in -- and using economics, uncovers the incentives and rational behavior that makes them, well, make a whole lot more sense. In this Halloween Special, Leeson and a16z's Hanne Tidnam dive into th...

Oct 31, 201728 minEp. 335

a16z Podcast: Revenge of the Algorithms (Over Data)... Go! No?

with Frank Chen, Steven Sinofsky, and Sonal Chokshi There are many reasons why we’re in an “A.I. spring” after multiple “A.I. winters” — but how then do we tease apart what’s real vs. what’s hype when it comes to the (legitimate!) excitement about artificial intelligence and machine learning? Especially when it comes to the latest results of computers beating games, which not only captures our imaginations but has always played a critical role in advancing machine intelligence (whether it’s AI w...

Oct 23, 201740 minEp. 334

a16z Podcast: Platforming the Future

with Tim O'Reilly and Benedict Evans In this hallway-style podcast conversation, O'Reilly Media founder Tim O'Reilly and a16z partner Benedict Evans discuss how we make sense of the most recent wave of new technologies --- technologies that are perhaps more transformative than any we've seen before -- and how we think about the capabilities they might have that we haven't yet even considered. O'Reilly has seen more than one wave of new tech make an impact over the last three decades in Silicon V...

Oct 13, 201734 minEp. 333

a16z Podcast: A New Lab Rises

with Ion Stoica, Peter Levine, and Sonal Chokshi We’ve already talked quite a bit about the Algorithms, Machines, and People lab at U.C. Berkeley (AMPLab) — all about making sense of big data — so what happens when the entire world moves towards artificial intelligence — and the need to make intelligent decisions on that data? That’s where the new RISElab (Real-time Intelligence Secure Execution) comes in. But what is a good “decision”, exactly? Beyond the existential question of that, what spec...

Oct 12, 201729 minEp. 332

a16z Podcast: Mindsets for Engineering Biology

Head of the largest bioengineering lab in the world, former chairman of the FDA and one of the few recipients of the National Medals of Science and of Technology and Innovation, Bob Langer's work has spanned multiple fields and settings and has been applied across numerous fields, from pharmaceutical to chemical, biotechnology to medical device companies. What does it mean to move across disciplines like this, from science to engineering, both in the lab and into the field? In this conversation ...

Oct 06, 201729 minEp. 331

a16z Podcast: Why Crypto Tokens Matter

with Chris Dixon and Fred Ehrsam We’ve already talked about why bitcoin matters. But as the set of cryptocurrencies — and networks and “tokens” enabled by the underlying blockchain — grow (Ethereum being one of the fastest-growing ones), where do we go from here? How do we tease apart the signal from the noise, given all the buzz and critiques out there? In this episode of the a16z Podcast, general partner Chris Dixon and Fred Ehrsam (former Goldman Sachs trader and a co-founder of Coinbase) bre...

Sep 28, 201735 minEp. 330

a16z Podcast: The Case Study of Lyft and Local Governments

with David Mack, Joseph Okpaku, and Matt Spence How should startups engage with policymakers, build their own government relations (GR) function (whether in house or with consultants), and just begin to figure out their GR playbook? Let alone explain their moves -- not just externally, but internally too? "We really viewed our first mission as education. Explaining what we were and, possibly more importantly, explaining what we weren't," shares Joseph Okpaku, vice president of governme...

Sep 26, 201721 minEp. 329

a16z Podcast: Exploding the Map

with Wei Luo, David Rumsey (@davidrumseymaps), and Hanne Tidnam (@omnivorousread) In this episode, Wei Luo, founding COO of DeepMap -- who build HD maps for autonomous vehicles -- and David Rumsey, founder of the David Rumsey Map Collection (one of the largest paper private map collections in the world, now at Stanford University, and the largest digital online private collection in the world, at 80,000 + maps) talk with a16z's Hanne Tidnam about how maps -- and mapmaking tools -- are changing i...

Sep 16, 201738 minEp. 328

a16z Podcast: Getting Applications Into People's Hands

with Juan Benet and Chris Dixon The story of how innovation happens is a long one — from government funding early basic research, to the heyday of corporate R&D like Bell Labs, to startups as experiments before product-market fit. Through all that, we’ve ended up with “unprecedented superpowers” distributed through the internet, and people building on top of it. Yet there’s still a huge lag in going from brilliant ideas in the form of research papers to an application that’s actually working...

Sep 15, 201722 minEp. 327

a16z Podcast: The Asshole Survival Guide

with Michael Dearing (@mcgd), Bob Sutton (@work_matters), and Hanne Tidnam (@omnivorousread) Bob Sutton's book The No Asshole Rule was all about how to foster company cultures that don't tolerate asshole behavior. But sometimes, dealing with an asshole is unavoidable -- in life or at work. So what are the best tactics to both protect yourself and to stop the asshole behavior? This is the subject that Sutton tackles in his new book, The Asshole Survival Guide. In this somewhat NSFW episode, a16z'...

Sep 13, 201735 minEp. 326

a16z Podcast: Adjusting to Trade... and Innovation

with Russ Roberts, Noah Smith, and Sonal Chokshi Beyond the overly simplistic framing of trade as “good” or “bad” — by politicians, by Econ 101 — why is the topic of trade (or rather, economies and people adjusting to trade) so damn hard? A big part of it has to do with not seeing the human side of trade, let alone the big picture across time and place… as is true for many tech innovations, too. Speaking of: how does the concept of “trade” fit with “innovation”, exactly? They’re both about getti...

Sep 10, 201738 minEp. 325

a16z Podcast: The Macro and Micro of Parenting

We tend to talk about tech and parenting through devices and artifacts -- screen time, to code or not to code -- but actually, there's a bigger, macro picture at play there: game theory, economic incentives, culture, and more. So in this back-to-school episode of the a16z Podcast, two economists -- Kevin Zollman, game theorist and philosopher at CMU and author of The Game Theorist's Guide to Parenting; and Fabrizio Zilibotti, macroeconomist at Yale working on a book called Love, Money and Parent...

Sep 05, 201730 minEp. 324

a16z Podcast: Competing Against Luck

with Clayton Christensen, Marc Andreessen, and Steven Levy In business, mistakes of omission may be just as bad as (if not worse than) mistakes of commission -- simply because of the loss in potential upside: new companies, new products, new opportunities for growth. Or even in the ability to respond to the disruption coming to one's industry and company... if it hasn't already. Sometimes, and in certain industries (such as hospitality and education), it just takes longer to pull off. But it's n...

Sep 02, 201737 minEp. 323

a16z Podcast: Engineering Intent

"Young hungry and scrappy" is how Hamilton described his country, and it's how many -- including the guests on this episode -- describe startups... or more precisely, the mindset that engineers in startups need to balance both creativity and efficiency. But what happens as those startups scale, accrue technical debt, standardize their frameworks, and hire even more engineers? How do they deliver on their product while also staying on top of -- or better yet, using and also pushing forw...

Aug 30, 201729 minEp. 322

a16z Podcast: A Society Under Construction - Modernizing Infrastructure

What is "infrastructure" actually? In the 19th and 20th century, that usually meant the transportation systems supporting roadways, airports, trains... but we don't even really know yet what it might potentially mean in the age of rapidly changing technology, autonomous vehicles, drones, and self-driving cars. In this episode, a16z's Matthew Colford discusses the infrastructure of the future with Anthony Foxx, former secretary of transportation under the Obama administration and former...

Aug 25, 201723 minEp. 321

a16z Podcast: Cash, Growth, and CEO ❤️ CFO

with Ben Horowitz, Scott Kupor, and Caroline Moon “The only unforgivable sin in business is to run out of cash” [so said Harold Geneen], yet startup CEOs “always act on leading indicators of good news, and lagging indicators of bad news” [according to Andy Grove]; after all, it requires a certain stubborn, headstrong optimism to start a company. So how to reconcile these views? At the very least, pay more attention to leading indicators of running out of cash, “because there’s just no going back...

Aug 25, 201720 minEp. 320

a16z Podcast: The Taxonomy of Collective Knowledge

What do disease diagnostics, language learning, and image recognition have in common? All depend on the organization of collective intelligence: data ontologies. In this episode of the a16z Podcast, guests Luis von Ahn, founder of reCaptcha and Duolingo, Jay Komarneni, founder of HumanDX, a16z General Partner Vijay Pande, and a16z Partner Malinka Walaliyadde break down what data ontologies are, from the philosophical (Wittgenstein and Wikipedia!) to the practical (a doctor identifying a diagnosi...

Aug 15, 201727 minEp. 319

a16z Podcast: Centers of Power, War, and History

with Graham Allison and Matthew Colford "When a rising power threatens to displace a ruling power, shit happens." It's true of people, it's true of companies, and it's even more true of countries. It's also the fundamental insight captured by ancient Greek historian Thucydides in his History of The Pelopennesian War. But where he was describing the war between Sparta and Athens, modern historian and political scientist Graham Allison describes how U.S. and China can escape this rising ...

Aug 11, 201729 minEp. 318

a16z Podcast: The Strategies and Tactics of Big

What happens when companies grow exponentially in a short amount of time -- to their organization, their product planning, their behavior towards change itself? In this "hallway conversation", a16z partners Steven Sinofsky and Benedict Evans discuss the business tactics and strategies behind four of the largest tech companies -- Google, Apple, Facebook, and Amazon -- and how they work from an org perspective. From the outside, these giants can seem composed of disparate entities litera...

Aug 07, 201730 minEp. 317

a16z Podcast: Independents on the Board

with Anne Mitchell, Lars Dalgaard, and Scott Kupor "Orthogonal thinking" but "shared core values" -- that's what makes an ideal board... especially when it comes to "independents", i.e., board members who aren't also investors. But how do you get the most out of those independent directors, who are often in the minority? How do you bring in the best board member for the company, team, product -- not just as another box to check on the road to IPO, but to ensure a fresh and/or missing perspective...

Aug 04, 201723 minEp. 316

a16z Podcast: From Mind at Play to Making the Information Age

with Jimmy Soni, Rob Goodman, and Steven Sinofsky Modern technology owes much to the introduction of the binary digit or "bit", first proposed by Claude Shannon in "A Mathematical Theory of Communication”, a paper published in 1948. The bit would go on to transform analog to digital, making Shannon the father of the information age. His contemporaries (and collaborators) included Vannevar Bush, Alan Turing, and other architects of the digital era. In this podcast, moderated by a16...

Aug 03, 201730 minEp. 315

a16z Podcast: The Curious Case of the OpenTable IPO

There are the things that you carefully plan when it comes to an IPO -- the who (the bankers, the desired institutional investors); the what (the pricing, the allocations); and the when (are we ready? is this a good public business?). But then there are the things that you don't plan: like the worst financial crisis since the Great Depression... as happened before the OpenTable IPO. There's even a case study about it. And so in this episode of the a16z Podcast, we delve into those lessons learne...

Jul 24, 201731 minEp. 314

a16z Podcast: Making a (Really) Wild Geo-Engineering Idea Real

Here’s what we know: There’s a pair (father and son) of Russian scientists trying to resurrect (or rather, "rewild") an Ice Age (aka Pleistocene era) biome (grassland) complete with (gene edited, lab-grown) woolly mammoths (derived from elephants). In Arctic Siberia (though, not at the one station there that Amazon Prime delivers to!). Here's what we don't know: How many genes will it take? (with science doing the "sculpting" and nature doing the "polishing")? How m...

Jul 18, 201730 minEp. 313

a16z Podcast: Addiction vs Popularity in the Age of Virality

In the age of virality, what does it actually mean to be popular? When does popularity -- or good product design, for that matter -- cross over from desire and engagement... to addiction? Journalist and editor Derek Thompson, author of Hit Makers: The Science of Popularity in an Age of Distraction -- and NYU professor Adam Alter, author of Irresistible: The Rise of Addictive Technology and the Business of Keeping Us Hooked -- share their thoughts on these topics with Hanne Tidnam in this episode...

Jul 15, 201727 minEp. 312

a16z Podcast: The Golden Era of Productivity, Retail, and Supply Chains

This episode of the a16z Podcast takes us on a quick tour through the themes of economics/historian/journalist Marc Levinson's books -- from An Extraordinary Time, on the end of the postwar boom and the return of the ordinary economy; to The Great A&P, on retail and the struggle for small business in America; all the way through to The Box, on how the shipping container made the world smaller and the world economy bigger. In this hallway-style conversation, Levinson and we (with Sonal Choksh...

Jul 11, 201733 minEp. 311

a16z Podcast: The Cloud Atlas to Real Quantum Computing

A funny thing happened on the way to quantum computing: Unlike other major shifts in classic computing before it, it begins -- not ends -- with The Cloud. That's because quantum computers today are more like "physics experiments in a can" that most companies can't use yet -- unless you use software, not just as cloud infrastructure for accessing this computing power commercially but for also building the killer app on top of it. What will that killer app be? With quantum virtual machin...

Jun 30, 201725 minEp. 310

a16z Podcast: Companies, Networks, Crowds

Is a network -- whether a crowd or blockchain-based entity -- going to replace the firm anytime soon? Not yet, argue Andrew McAfee and Erik Brynjolfsson in the new book Machine, Platform, Crowd. But that title is a bit misleading, because the real questions most companies and people wrestle with are more "machine vs. mind", "platform vs. product", and "crowd vs. core". They're really a set of dichotomies. Yet the most successful systems are rarely all one or all the...

Jun 29, 201736 minEp. 309

a16z Podcast: Lobbying Tech

What is lobbying, really? Is it “white", "heavy-set" men "playing golf" and making arrangements in "smoke-filled back rooms”? It's not like that anymore, according to two lobbyists who join this episode of the a16z Podcast to pull back the curtain on this practice… and share what’s changed: Heather Podesta, founder of Invariant (and a lawyer by training), and Michael Beckerman, President and CEO of the Internet Association (an industry trade association that also ha...

Jun 24, 201722 minEp. 308