There have been a number of new device announcements this past month -- from Google’s new Pixel phone (the first time they made their own phone on the hardware side as well) to more recently, Apple’s announcements around a new Macbook Pro and innovations in touch (including a Touchbar that replaces function keys and bringing TouchID to Macs); and then Microsoft, which among other things announced a new Surface Studio -- an all-in-one touchscreen desktop PC. How do these change the future of work...
Oct 29, 2016•34 min•Ep. 247
Once we sequenced the human genome, we'd know the cause of -- and therefore be able to help cure -- all diseases... Or so we thought. Turns out, 20,000 genes (and counting) didn't really explain why disease occurred. Sure, some could be explained by mutations in a single genome, but most, like cancer, are too damn complex. And while the focused, singular approach to understanding disease did yield some useful therapeutics, it's now reached its limits. It hasn't helped much on the diagnostics (an...
Oct 18, 2016•31 min•Ep. 246
From glittery reaction gifs modded by grandparents to rage faces on Reddit, stickers (gifs and other layered images) and emotive “biaoqing” have taken over messaging culture in China and beyond. Stickers are tied to filter culture, too — whether originating in real life as purikura photo sticker booths in Japan or digitally as Snapchat filters. Why are these forms of social communication so popular? Because sometimes you just want to say “I feel totally Nicki Minaj side-eye dot-GIF about this”, ...
Oct 12, 2016•47 min•Ep. 245
The most recent Oculus Connect event (the third and largest yet) has been lauded as bringing us closer than ever to the future promised for virtual reality or VR. There have been many hardware moves by many players, both recently and over the past year. Who's in it to win it? How far are we from the "holy grail" of headsets that will truly mainstream VR? Will the killer app -- or layer -- for VR be social? And is there enough enthusiasm and activity to get us past the "trough of d...
Oct 10, 2016•36 min•Ep. 244
This special episode of the a16z Podcast is based on a Q&A from an early screening we hosted of Disney's Queen of Katwe, now in theaters. The movie -- directed by Mira Nair and based on a book by Tim Crothers -- depicts the true story of Ugandan chess prodigy Phiona Mutesi. The conversation, hosted by Ben Horowitz, features actor David Oyelowo who (among other roles, previously played Dr. Martin Luther King, Jr. in "Selma") and plays Robert Katende, the engineer-turned-mentor who t...
Sep 30, 2016•22 min•Ep. 243
From the silver age of on-prem software companies like SAP and Siebel Systems to the golden age of enterprise software-as-a-service, we're now seeing an explosion of data. All types, all sizes, and all over the place. And much of it is a sort of industrial "data exhaust", where companies aren't quite sure what question to ask of the data but are being bombarded with data due to the variety of data sources available today -- from websites to sensors (and therefore data capture) everywhe...
Sep 22, 2016•28 min•Ep. 242
Just as "social networking" is a bland term that doesn't really capture the layers of what happens underneath (and on top of) social networking platforms, "crowdfunding" is a broader phenomenon than what the term and tools implies. Or so argue the guests on this episode of the a16z Podcast, Tilt co-founder and CEO James Beshara and a16z general partner Jeff Jordan with Sonal Chokshi. Crowdfunding isn't just about reaching a certain threshold to make something, but it's also a...
Sep 18, 2016•28 min•Ep. 241
"Apple isn't just a tech company; it's a tastemaker." Remember the iconic ads of dancing silhouettes in black, with only the headphone wires visible in white? They were a critical part of the larger buy-Apple innovation narrative. So what happens now when those wires -- an emblematic and enduring image -- are no longer visible, as is the case with the removal of the traditional headphone jack in iPhone 7? It's part of a broader story, both about how product narratives are shared/told a...
Sep 13, 2016•34 min•Ep. 240
Sleep, productivity, and creatively are intimately linked, for better and for worse. And "we are living under a collective delusion that burnout is the way to succeed," observes Arianna Huffington, author of The Sleep Revolution. Not only does this affect our health and resilience, she argues, but the data shows that even though we are working longer hours than ever, we lose 11 days of productivity a year per employee due to sickness or diminished capacity. (It also hurts our ability t...
Sep 06, 2016•28 min•Ep. 239
"Incremental change may be good theory, but in practice you have to have a big enough stick to hit everybody with to make everything move at once". So shares Adrian Cockcroft, who helped lead Netflix's migration from datacenter to the cloud -- and from monolithic to microservices architecture -- when their streaming business (the "stick"!) was exploding. So how did they -- and how can other companies -- make such big, bet-the-company kind of moves, without getting mired in fa...
Aug 31, 2016•27 min•Ep. 238
For better or worse, most of the computing systems that run much of our lives (whether invisibly or visibly) have become increasingly complex -- they're not fully engineered; they're almost grown. And with that we enter a brave new world of "biological" (as opposed to a more "physics") mindset applied to computing. It's more like evolution, horns and all. This isn't just abstract or backend-only stuff. Complex system design affects everything from datacenters and SaaS to word...
Aug 30, 2016•19 min•Ep. 237
Bitcoin quickly made its way from a whitepaper to a production network, which is pretty amazing when you think about it. But its scripting/ programming language was initially, intentionally, limited for a few reasons, which meant that building new apps on bitcoin wasn't always easy. Enter ethereum in 2014 -- a public blockchain platform that moved away from the "Swiss-army knife" approach to a more general protocol approach. This would in turn allow endless (and entirely new) use cases...
Aug 28, 2016•50 min•Ep. 236
Now that we know to price and plan early, price high -- especially for category-creating or "pre-chasm" businesses -- how do we handle freemium models? While free to premium is a great way to get bottoms-up, often viral traction in an enterprise, the challenge is figuring out just where and how to "draw the line" between where free ends and paid begins. Especially for open source, which while not necessarily free/mium, is also affected by these questions. And in that case, ho...
Aug 19, 2016•33 min•Ep. 235
"Raise prices." Regular listeners of our podcast have heard this advice more than once. But why is this so key and yet so hard for many technical founders? And how should startups go about raising prices -- or more specifically, creating value -- for their products? In this episode of the a16z Podcast, former sales VP Mark Cranney (and head of a16z's EBC and go-to-market practice for startups) and former startup founder (and general partner focused on all things infrastructure) Martin ...
Aug 14, 2016•37 min•Ep. 234
This podcast is all about emoji. But it's really about how innovation really comes about -- through the tension between standards vs. proprietary moves; the politics of time and place; and the economics of creativity, from making to funding ... Beginning with a project on Kickstarter to crowd-translate Moby Dick entirely into emoji to getting dumplings into emoji form and ending with the Library of Congress and an "emoji-con". So joining us for this conversation are former VP of Data a...
Aug 03, 2016•38 min•Ep. 233
From hardware and hardwires to smartphones and social, technology wants to connect. It's almost a native property of technology and especially software businesses, which is why network effects matter. "It was endemic to these technologies that they wanted to become connected and once connected, they become networks and once networks, they become network effects. Other products like cars or toasters or houses or whatever, aren't natively connected physically or through information sharing,&q...
Aug 01, 2016•22 min•Ep. 232
Seemingly overnight, a single game -- Pokémon Go -- has taken people by storm. But it's a game that was technically years in the making, building on a legacy of creative intellectual property and technologies such as mobile, geomapping/ geolocation, computer vision, and more. And since "toys are the prelude to serious ideas" [Charles and Ray Eames] or "the next big thing will start out looking like a toy" [Chris Dixon via Clayton Christensen], we want to understand this pheno...
Jul 22, 2016•36 min•Ep. 231
One of the biggest misconceptions around network effects (which are one of the key dynamics behind many successful and highly defensible software companies) is confusing growth with engagement. So how does one tell the difference between viral growth and network effects? How does one create network effects in different businesses? (Hint: it's not by accident!) How do you know when to hang in there because you see signs of network effects or just drop it and move on to something else? And what ar...
Jul 15, 2016•48 min•Ep. 230
We already know that the government is one of the largest IT buyers, but in many ways it is also an IT builder. Especially for areas where the government is doing something that no one else is doing, like running Medicare and Social Security -- i.e., unique services no other company out there is building software for. That's where the USDS comes in. Now almost two years old, the United States Digital Services is "a startup at the White House" responsible for mission-critical, citizen-f...
Jul 14, 2016•24 min•Ep. 229
"All of a sudden you can program the world" -- it's the continuation of the software eating the world thesis we put out over five years ago, and of the trajectory of past and current technology shifts. So what are those shifts? What tech trends and platforms do we find most interesting on the heels of raising our fifth fund? Are we just building on and extending existing platforms though, or will there be new platforms; and if so, what will they be? Well, distributed systems for one......
Jul 11, 2016•41 min•Ep. 228
Do we need a new pay system for the way startup employees are compensated? While many people agree that the current 90-day exercise practice — an outdated relic of when companies used to go public/get liquidity in a much shorter timeframe — is far from ideal, neither are some of the other solutions proposed so far. Because incentives matter, and behavior follows incentives. Which is fine as long as you know all the implications around what you’re incentivizing for and it aligns to what you want ...
Jul 01, 2016•33 min•Ep. 227
with Fei-Fei Li (@drfeifei), Frank Chen (@withfries2), and Sonal Chokshi (@smc90) Who has the advantage in artificial intelligence — big companies, startups, or academia? Perhaps all three, especially as they work together when it comes to fields like this. One thing is clear though: A.I. and deep learning is where it’s at. And that’s why this year’s newly anointed Andreessen Horowitz Distinguished Visiting Professor of Computer Science is Fei-Fei Li [who publishes under Li Fei-Fei], associate p...
Jun 28, 2016•38 min•Ep. 226
How far along are we towards the vision of a "cashless, cardless, walletless, frictionless future" for fintech? We're not quite there yet, argued BuzzFeed News technology reporter Charlie Warzel in a recent feature story -- for which he got a microchip implanted in his finger while trying to go cashless for an entire month. But as revolutionary as the chip tech seems, the reality may be that fintech innovation is much more incremental, evolutionary, and still only disintermediating the...
Jun 22, 2016•46 min•Ep. 225
Love the term or hate it, the concept and reality of the "sharing economy" (or "gig economy" and so on) is here to stay. And in fact, argues NYU Stern professor and researcher Arun Sundararajan, it may even reduce the income distribution gap between the haves and have-nots in a way that previous shifts -- like the Industrial Revolution and traditional 20th century institutions -- never did. How? Because it's a new model for (crowd-based) capitalism -- one where we're increasi...
Jun 16, 2016•28 min•Ep. 224
The world's most valuable company, Apple, made a number of seemingly incremental announcements at its most recent annual developer's conference (WWDC) -- that Apple Pay is coming to the web; that Siri is being opened up to app developers; that iMessage will suggest emoji; and many other things. Underneath all these little feature tweaks however is a bigger story, argue a16z's Benedict Evans, Frank Chen, and Kyle Russell. It's a story about -ification: the "platformification" of apps av...
Jun 14, 2016•25 min•Ep. 223
The mindset of "move fast and break things", while great for code, isn't exactly great for the human body. So adding computation to biology -- especially in the slow-moving pharmaceutical industry, where drug approval can take years -- brings with it both opportunities (like drastically faster discovery and assessment) and challenges (the need for hard evidence, not just soft-ware). But there's more: We don't want just better outcomes for healthcare. We want better outcomes at a cheape...
Jun 14, 2016•29 min•Ep. 222
Technology has always been a force in how we live, work, and play; only now it's accelerating and compounding in unexpected ways. But just because we don't know exactly what form that tech will take (sharing homes on Airbnb or cars with Lyft and Uber for example) doesn't mean that the larger force at play (e.g., sharing) didn't have a certain predictability to it. It was almost an inherent -- and inevitable -- outcome of the very nature of the internet itself. And there are at least 12 such inev...
Jun 07, 2016•42 min•Ep. 221
"Anybody who is interested in China, who's developing things in China, who's doing business with China needs to be thinking about the instinct towards politics over pragmatism", argues New Yorker staff writer (and former Beijing resident) Evan Osnos. "It will affect your operations there. It's not the kind of thing where you can be, 'Well, look, we're not interested in politics.'" Osnos, who also wrote the award-winning book The Age of Ambition: Chasing Fortune, Truth, and Fa...
Jun 02, 2016•43 min•Ep. 220
Everything old is new again when it comes to startup ideas and how technology innovation happens. But practically, how does that apply to starting and/or working at startups — especially since the default state of every company is “dying in obscurity”? In this episode of the a16z Podcast, Marc Andreessen and 21 co-founder Balaji Srinivasan cover everything from deciding what ideas to work on and the optimal type of startups to work at, to the funding environment and pendulum swings of deciding w...
May 30, 2016•54 min•Ep. 219
"We really want Apple here... Would you please call Tim Cook?" That's just one of the things Penny Pritzker, the 38th Secretary of Commerce has heard as she and the U.S. Department of Commerce engage in "commercial diplomacy" around the world. Their job is to help overcome trade barriers, represent the interests of entrepreneurs and drive administrative policy change as it relates to technology, and be on the frontline of helping small and medium-sized businesses in markets a...
May 27, 2016•30 min•Ep. 218
