3-minute 3Rs February 2018

In this month's 3-minute 3R's, we're talking temperature, environmental enrichment to improve stress responses in zebrafish, and better ways to handle mice.The papers behind the pod:Mice Housed at Elevated Vivarium Temperatures Display Enhanced T-cell Response and Survival to Francisella tularensis: http://www.ingentaconnect.com/content/aalas/cm/2017/00000067/00000006/art00004Heat or Insulation: Behavioral Titration of Mouse Preference for Warmth or Access to a Nest: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0032799International survey on the use and welfare of zebrafish Danio rerio in research: http://onlinelibrary.wiley.com/doi/10.1111/jfb.13278/abstractEnvironmental enrichment modulates the response to chronic stress in zebrafish: http://jeb.biologists.org/content/early/2018/01/09/jeb.176735Handling method alters the hedonic value of reward in laboratory mice: https://www.nature.com/articles/s41598-018-20716-3The pod was produced this month with contributions from Lab Animal (www.nature.com/laban), the NC3Rs in the UK (www.nc3rs.org.uk), and the North American 3Rs Collaborative (www.na3rsc.org).

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