3-Minute 3Rs August 2018

You're listening to the August edition of 3 Minute 3Rs, brought to you this month by the NC3Rs (www.nc3rs.org.uk), the North American 3Rs Collaborative (www.na3rsc.org), and Lab Animal (www.nature.com/laban) This month, we'll be talking about non-primate alternatives to study polio, aging & frailty indexes, and training rats with out water restriction.The papers behind the pod:* Replacement of primary monkey kidney cells by L20B cell line in the test for effective inactivation of inactivated poliovirus vaccine:https://www.sciencedirect.com/science/article/pii/S0166093417306006* Senolytics improve physical function and increase lifespan in old age: http://www.nature.com/articles/s41591-018-0092-9* A Comparison of Two Mouse Frailty Assessment Tools: https://academic.oup.com/biomedgerontology/article/72/7/904/3854927* Training Rats Using Water Rewards Without Water Restriction: https://www.frontiersin.org/articles/10.3389/fnbeh.2018.00084/full

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