There’s a maternal health crisis in the United States, with high rates of maternal mortality, especially among marginalized communities. But what is being done to improve it? Through conversations with those on the front lines, we uncover the stark health inequities that exist in maternal healthcare and the developments created to tackle them. We also hear from mothers who have firsthand experience with Preeclampsia—a serious pregnancy complication and one of the many causes of maternal mortalit...
Dec 03, 2024•46 min•Transcript available on Metacast How will evolving digital technologies impact healthcare delivery, patient experience, and access to care? According to new venture-backed companies, they can advance health equity, democratize access, and empower individuals to take control of their health journey. Alongside industry pioneers and investors, we explore digital health advancements such as telemedicine, remote monitoring, and data-driven diagnostics that are all working to improve healthcare efficiencies. Join us as we uncover the...
Nov 19, 2024•38 min•Transcript available on Metacast Join us in Kotzebue, Alaska to explore the issue of rural healthcare and the inequities faced by these communities. We shine a light on innovative solutions aimed at improving rural healthcare delivery, like a program called Siamit that’s connecting cutting-edge medicine from Massachusetts General Hospital (MGH) and Harvard Medical School to the tribal regions of Alaska. We also look at the role of venture capital in driving advancements that promote access to healthcare for those living in rura...
Nov 05, 2024•41 min•Transcript available on Metacast Prescription drug prices in the United States are 2.78 times higher than in other developed countries, but why? We untangle the barriers surrounding drug affordability and find out why accessing life-saving medications is costly to so many. Joined by experts, advocates, and one Cystic Fibrosis patient relying on expensive medication to live, we examine the complex factors contributing to the high costs of drugs, from research and development to pricing strategies and supply chain dynamics. We al...
Oct 22, 2024•43 min•Transcript available on Metacast Join us as we head to the Bronx to examine the critical intersection of housing and health and the innovative solutions that are aiming to address the affordable housing crisis in major cities like New York and LA. Through conversations with non-profit leaders and impact investors, we dive into how affordable housing impacts public health and health equity, highlighting the investment strategies and community partnerships that are moving the needle. We also discuss the challenges of housing inse...
Oct 08, 2024•34 min•Transcript available on Metacast How does venture capital contribute to advancing health equity and public health? Find out on season five of Unseen Upside , premiering Tuesday, October 8. This season, we dive into how today's investment decisions are shaping tomorrow's innovations in critical areas such as affordable housing, maternal health, drug pricing, and more. Join us for engaging conversations with investors and entrepreneurs as we uncover the profound impact of venture capital on our lives on a grand scale. Powered by ...
Oct 01, 2024•3 min•Transcript available on Metacast While we’re busy pulling together stories for the fifth season of Unseen Upside , we thought you might be curious about what it is that Cambridge Associates actually does. In a nutshell, we have the privilege of partnering with some of the world’s top institutional investors—like nonprofits, universities, hospitals, pension plans, and even private families—and we try to help them reach their investment goals. Recently, we had a conversation with four of our non-profit clients from institutions w...
Aug 14, 2024•34 min•Transcript available on Metacast Artificial intelligence is transforming healthcare, unleashing new investment opportunities. From cancer screening to drug discovery, AI promises to augment clinical decision-making and improve care. We’ll explore the surging ecosystem of medical AI innovations, from the emerging tech landscape to practical deployment. But what are the challenges facing real-world implementation? Which applications show the most promise? Join us as we investigate how artificial intelligence can change healthcare...
Apr 16, 2024•47 min•Transcript available on Metacast Autoimmune diseases like lupus impact over 5 million patients globally, but treatment options remain limited. Now, decoding the once mysterious "dark genome" could bring new therapies. Over 90% of our DNA was once considered "junk"—but we’ve learned this dark matter regulates gene expression and human disease. This episode takes you to the pioneers who are unlocking the dark genome's potential to correct root causes of complex conditions like lupus. We'll chat with those illuminating this unchar...
Apr 02, 2024•44 min•Transcript available on Metacast Obesity is a global health crisis, with over 650 million adults affected worldwide. This drives massive economic and disease burdens. Yet new treatment options like GLP-1 drugs offer hope. This episode analyzes the investment landscape and future of obesity therapeutics, focusing on transformational GLP-1 drugs like Ozempic that curb appetite. Join us as we investigate the promise and challenges of emerging anti-obesity drugs, learn about one patient’s journey taking them, and discover what the ...
Mar 19, 2024•44 min•Transcript available on Metacast Precision oncology represents an exciting shift in cancer treatment from a one-size-fits-all approach to personalized care based on each patient's unique cancer and molecular makeup. In this episode, we'll explore how precision oncology is transforming the landscape of cancer care and improving outcomes at leading hospitals like St. Jude Children’s Research Hospital. We'll discuss the latest precision diagnostic technologies enabling doctors to analyze a tumor's molecular profile and match targe...
Mar 05, 2024•39 min•Transcript available on Metacast Thanks to medical advances, we're living longer lives but with that comes rising rates of Alzheimer's disease. Currently 6 million Americans have Alzheimer's, and that could triple by 2050. This episode explores emerging innovations offering hope against neurodegenerative diseases. We'll discuss promising new drugs that could slow cognitive decline and the strides scientists are making towards understanding causes and developing therapies—and how these breakthroughs are giving hope to one family...
Feb 20, 2024•41 min•Transcript available on Metacast The mental health crisis is growing, especially among Gen Z (91% report anxiety or depression). This episode explores innovations in mental healthcare access, new therapeutic approaches for young people and families, and how hospitals are striking creative partnerships to tackle this emergency. Tune in to learn what’s working and showing promise in mental healthcare, glimpses of what the future could look like, and where persistent gaps remain. Hear from leaders Melody Dickerson (VHC Health); Em...
Feb 06, 2024•30 min•Transcript available on Metacast The future of healthcare is here. Get an an inside look at the innovations transforming lives on season four of Unseen Upside , premiering Tuesday, February 6. This season, we pull back the curtain on cutting-edge advancements at the intersection of technology and medicine, learn how AI is revolutionizing diagnostics and treatment, discover the potential of GLP-1s to combat obesity, and how breakthrough Alzheimer's therapies are offering hope to millions. We'll also uncover creative approaches t...
Jan 30, 2024•3 min•Transcript available on Metacast The fashion industry accounts for up to 10% of global carbon dioxide output and roughly 2.6 million tons of clothing returns end up in US landfills each year instead of being resold. Meanwhile, the shipping for these returns account for around 16 million tons of CO2 emissions—and fast fashion is making things worse. But what if deep tech could help to cut down on returns? Amid the rise of conscious consumerism, one company is using video game technology and AI generated avatars to help online...
May 30, 2023•36 min•Transcript available on Metacast More than two-thirds of our electricity is generated by burning fossil fuels, a major climate change contributor. As such, use of renewable energy is expected to double in the next 15 years. But there’s a catch: the power they generate depends on variable factors like wind and sun, making them too unreliable to power our grid. However, recent battery innovations could be the solution. One company has developed an iron-air battery capable of storing energy for multiple days, which may be the miss...
May 16, 2023•38 min•Transcript available on Metacast Humans have fantasized about flying cars for decades, but they’ve yet to leave the pages of our sci-fi books...or have they? Join us as we visit Joby Aviation out in Marina, California to witness their eVTOL (electric vertical take-off and landing) aircraft take flight. With plans to operate like ubers in the sky, eVTOLs are the closest thing we have to flying cars—and they could be a commercial reality by 2025. The companies creating them promise a faster and greener mode of transportation, but...
Apr 27, 2023•31 min•Transcript available on Metacast According to scientists, 30,000 species per year are being driven towards extinction and 50% of all species could be extinct by 2050 due to climate change. But what if there was something we could do, in addition to conservation, to change this trajectory? That’s what the scientists and engineers at Colossal Biosciences are working towards: reversing extinction. Using CRISPR and advanced gene editing techniques, they plan to bring back the woolly mammoth and the dodo bird to help combat climate ...
Apr 11, 2023•39 min•Transcript available on Metacast Harnessing fusion power has been an elusive goal of physicists and researchers for decades. However, recent scientific advances are helping to make that goal a reality. Described as a star in a bottle, fusion is what powers our sun and stars, offering us the prospect of limitless clean energy. But here on earth, it has presented unresolved engineering challenges—until now. Commonwealth Fusion Systems is on the brink of delivering commercial fusion energy thanks to their revolutionary magnet. But...
Mar 28, 2023•32 min•Transcript available on Metacast Season three of Unseen Upside: Investments Beyond Their Returns by Cambridge Associates explores the innovations turning science fiction to fact and the people investing in them. Powered by the global network of Cambridge Associates, discover the investments being made that will redefine our future. Join us to uncover the Unseen Upside.
Mar 20, 2023•2 min•Transcript available on Metacast We’ve all dreamt of traveling to outer space and recently, that dream has been more tangible than ever. But for those of us without a seat on the next rocket, how will space innovation improve our lives here on Earth? It turns out that the microgravity environment of orbit provides manufacturing capabilities that aren’t possible on earth. It allows us to create things—think artificial organs, life-saving pharmaceuticals, fiber optic cables, and other products—that are superior to those created o...
Jun 14, 2022•41 min•Transcript available on Metacast Oceans make up 72% of the earth’s surface and have absorbed around 40% of carbon emissions since 1840. As such, investors are increasingly putting capital to work in ocean-based businesses to both mitigate climate change and enhance the Blue Economy—but how? In this episode, we visit Running Tide in Portland, ME to see this concept in action. They use advanced aquatic growing systems and data science to grow shellfish and kelp forests. The result? A highly nutritious, sustainable protein and a n...
Jun 02, 2022•40 min•Transcript available on Metacast Fire is often a marker associated with the worst effects of climate change. But what if fire could actually be harnessed to help reverse it? In this episode, we meet Diamond Foundry, a company revolutionizing the diamond industry with their affordable, lab-created diamonds—free from the myriad of problems associated with the mining process. We’ll learn about the social and environmental impacts of this exploding industry and how investors are rethinking the carbon footprints of their portfolios....
May 17, 2022•39 min•Transcript available on Metacast For most of human history, we’ve been cutting down trees. However, the acceleration of carbon credit markets and the societal demand for climate solutions are pushing us to re-think our relationship with them. So how can investors earn a compelling return from planting trees while helping to sequester carbon and increase biodiversity? We’ll travel to Broadclyst, England to experience the innovation surrounding reforestation and how one organization has the lofty goal of planting 20 million trees...
May 03, 2022•39 min•Transcript available on Metacast Livestock take up nearly 80% of global agricultural land yet produce only 20% of the world’s supply of calories—so how can we make feeding people more efficient? In this season two premiere of Unseen Upside , we visit an alternative protein company in Boulder, Colorado called Meati. There, we explore how a nutrient-rich fungi called mycelium is changing the game when it comes to protein consumption. It’s better for people and the planet—yet somehow doesn’t compromise on flavor. We’ll learn about...
Apr 19, 2022•36 min•Transcript available on Metacast Season two of the Unseen Upside podcast by Cambridge Associates explores elements of our natural world—and beyond—with the innovators and investors aiming to enhance and protect our future. Powered by the global network of Cambridge Associates, host Luke Charest will explore the investments being made that will improve our lives in unexpected ways. Join us to uncover the Unseen Upside.
Apr 11, 2022•3 min•Transcript available on Metacast Consumers are demanding more from brands than ever before, but how are brands rising to the occasion? In this episode of Unseen Upside , Cambridge Associates’ Global Head of Private Investments, Andrea Auerbach , looks at how technology, coupled with evolving consumer preferences, are impacting how both startups and incumbent brands market themselves. We also speak with Jenny Gyllander , Founder of Thingtesting and Robin Tsai and Wayne Wu , both General Partners at VMG Partners....
Nov 16, 2021•23 min•Transcript available on Metacast In this episode of Unseen Upside , we look at how technology is transforming healthcare for both the provider and the patient—and making it more equitable. Sami Inkinen , CEO and Co-Founder of Virta Health will discuss how his company is treating and reversing diabetes through an app on your phone. We also speak with J asmine Richards , Cambridge Associates' Head of Diverse Manager Research; Tuoyo Louis , Co-Founder of Seae Ventures; and Rochelle Witharana , CFO of The California Wellness Founda...
Nov 02, 2021•34 min•Transcript available on Metacast In this episode of Unseen Upside , we’ll explore how non-fungible tokens (NFTs)—and the blockchain technology that supports them—are enabling a revolution in how artists and creators earn a living. You’ll hear from Cambridge Associates’ Joe Marenda and Kenneth Tom ; Dawn Harflinger , President & CEO of Queen Lili`uokalani Trust in Hawaii; Maria Shen , Partner at Electric Capital; and Cooper Ray , a photographer based in New York City....
Oct 20, 2021•31 min•Transcript available on Metacast Now more than ever, we rely on high-speed internet to power our work and personal lives—but where does it come from? In this episode of Unseen Upside , we visit Cambridge Associates’ Minesh Mashru in Amsterdam to discuss digital infrastructure and the investments being made in fiber optic cables. We’ll also meet Simon Soder , a Partner at Antin Infrastructure Partners in Paris, Aaron Werley , Vice President of Architecture & Engineering at Zayo Group, and Andrew Kwok , the CEO of HGC Global ...
Sep 28, 2021•24 min•Transcript available on Metacast 
