Stable glucose levels are a foundation of feeling and looking your best at any age. When glucose levels are more erratic—with spikes and crashes—cravings, weight gain, low energy, health issues, and more can ensue. Jessie Inchauspé and Dr. Casey Means, thought leaders on the topic of blood sugar, discuss simple hacks for keeping glucose levels more stable without resorting to restrictive diets, and they share why stable levels inform health. Sign Up to Get Your Free Ultimate Guide to Glucose: ...
Feb 20, 2025•1 hr 13 min•Ep 271•Transcript available on Metacast Diet and exercise culture tends to prioritize calorie restriction and calorie burning via cardio workouts. While fat loss is beneficial, building and maintaining healthy muscle mass is also crucial for metabolic health and longevity. Dr. Gabrielle Lyon and Dr. Casey Means discuss Lyon’s book “Forever Strong,” why strength-training should be a priority for workout routines, how muscle is the body’s metabolic currency, and why boosting protein intake aids in adding and preserving muscle mass. Sign...
Jan 30, 2025•1 hr 3 min•Ep 270•Transcript available on Metacast Levels, aiming to fix the metabolic health crisis with the use of continuous glucose monitoring (CGM) paired with an intuitive and educational app, was founded in 2019 by Josh Clemente, who eventually brought on several co-founders to help steer the startup’s ship. Josh Clemente and Ben Grynol discuss Clemente’s lightbulb moment for the concept, the networking process for gaining investor buy-in and taking the company to the next level, and the hiccups and triumphs along the way. Sign Up to Get ...
Dec 19, 2024•4 hr 46 min•Ep 269•Transcript available on Metacast The obesity epidemic isn’t about calories-in-calories-out. Instead, chronic stress and high insulin levels from refined carbs and sugar are drivers of fat storage. And the type of fat stored matters, since visceral fat accumulation leads to worsening metabolic health. Dr. Robert Lustig and Mike Haney discuss the different types of fat and how they are stored and burned; what thin on the outside, fat on the inside means; whether people can be healthy at any size; environmental factors that contri...
Nov 21, 2024•2 hr 35 min•Ep 268•Transcript available on Metacast Trauma causes physiological changes to the nervous system. Over time, these impacts may place someone on a trajectory from health to a pre-disease state to a disease state, leading to autoimmunity or autoimmune disorders. Dr. Sara (Gottfried) Szal and Mike Haney discuss Szal’s new book “The Autoimmune Cure,” trauma and how it can contribute to autoimmunity, how personalized precision medicine may help individuals reverse autoimmunity and return to a state of health, and how psychedelic therapies...
Oct 24, 2024•1 hr 13 min•Ep 267•Transcript available on Metacast Inflammation is an essential process in the body to help with healing and illness recovery. However, many people have chronic inflammation, which accelerates aging and drives disease processes. We can help control inflammation through diet. Dr. Robert Lustig and Ben Grynol discuss environmental and dietary sources of chronic inflammation as well as the foods that are anti-inflammatory. Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl Levels helps yo...
Oct 10, 2024•18 min•Ep 266•Transcript available on Metacast Although not one single test can tell you whether you are healthy, some biomarkers and lab results can provide you a picture of your metabolic health, which can then inform you about your overall health. Dr. Robert Lustig and Mike Haney discuss why fasting insulin is one of the best metabolic health biomarkers, how you can use continuous glucose monitoring as a proxy for insulin sensitivity, how fast your metabolic health can change, and why your uric acid level and the cholesterol marker ApoB a...
Sep 26, 2024•1 hr 20 min•Ep 265•Transcript available on Metacast Both aging and menopause affect metabolism. Unless people build and preserve muscle mass, aging drives muscle loss and fat gain. While these changes affect everyone, the menopause transition can also worsen metabolic health. Dr. Robert Lustig and Ben Grynol discuss aging’s effects on body composition, how menopause exacerbates these and other effects, and what you can do to protect your health. Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl Levels...
Sep 12, 2024•11 min•Ep 264•Transcript available on Metacast Macronutrients include fat, protein, and carbohydrates. Fiber is a type of carbohydrate. All four nutrients have different effects on glucose and metabolic health. Dr. Robert Lustig and Ben Grynol discuss the metabolic health effects of each macronutrient, how to prevent age-related muscle loss, how to improve gut health, and more. Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl Levels helps you see how food affects your health, empowering you with t...
Aug 29, 2024•37 min•Ep 263•Transcript available on Metacast Exercising and changing your diet are both beneficial for metabolic health. But you may be wondering which one has more benefits for fat loss, increasing insulin sensitivity, and more. Dr. Robert Lustig and Ben Grynol discuss the answer to this burning question and more, including how exercise, saunas, stress, and sleep affect glucose levels. Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl Levels helps you see how food affects your health, empowering y...
Aug 15, 2024•17 min•Ep 262•Transcript available on Metacast High uric acid can cause gout, but it’s also a marker for worsened metabolic health and gut health and a contributor to neurodegenerative diseases, such as Alzheimer’s. Consumption of purines can lead to high uric acid levels, but other ingredients in our food system are also culprits. Dr. David Perlmutter and Dr. Casey Means discuss the problems with high uric acid, the foods and drinks that can lead to higher levels, why uric acid can be a driver of worsened brain health, and concerns regardin...
Aug 01, 2024•1 hr 9 min•Ep 261•Transcript available on Metacast High insulin levels drive the growth of fat cells. In turn, fat gain can exacerbate insulin resistance, leading to a vicious cycle. Insulin is a hormone the pancreas releases in response to glucose rising in the bloodstream. A lower insulin level is required to lose fat, and dietary habits and lifestyle changes can help. Dr. Robert Lustig and Ben Grynol discuss insulin’s dual functions in the body, why high insulin leads to fat storage, and how to lower insulin levels. Sign Up to Get Your Free U...
Jul 11, 2024•12 min•Ep 260•Transcript available on Metacast Before someone develops type 2 diabetes, they go through a prediabetic stage. But if someone is reversing their diabetes and is trending toward better glucose levels or even optimal levels, they are postdiabetic. Eric Edmeades and Ben Grynol discuss Edmeades’s new book “Postdiabetic,” his company Wildfit, and how the program helps people reverse type 2 diabetes, change their relationship with food, and overhaul their health. Sign Up to Get Your Free Ultimate Guide to Glucose: https://leve...
Jul 04, 2024•1 hr 1 min•Ep 259•Transcript available on Metacast Excess glucose from food gets stored as fat. And our insulin response drives that fat storage. The goal is for the pancreas to release less insulin but for the body to have a healthy response to it. Dr. Robert Lustig and Ben Grynol discuss the interplay between glucose and insulin, healthy glucose numbers, and the problems with insulin resistance. Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl Levels helps you see how food affects your health, empowering ...
Jun 20, 2024•33 min•Transcript available on Metacast Why are we spending more on health care every year, yet people are getting sicker? “Good Energy,” a book by Casey Means, MD, details how you can take your health into your own hands with the power of food as medicine. Dr. Casey Means and Dr. Robert Lustig discuss the overarching themes of “Good Energy,” why we need changes in government and health care, and how people can overhaul their own health with actionable tips, such as eliminating ultra-processed foods from their diet. Plus, Means answer...
Jun 14, 2024•1 hr 4 min•Ep 257•Transcript available on Metacast About 93% of people in the United States are not metabolically healthy. But metabolic health can be improved quickly and over time with lifestyle changes. Dr. Robert Lustig and Ben Grynol discuss what metabolism is, how to determine metabolic health status, and how and why maintaining metabolic health is crucial. Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl Levels helps you see how food affects your health, empowering you with the tools needed to achieve he...
Jun 06, 2024•10 min•Ep 256•Transcript available on Metacast A lean mass hyper-responder is someone with high LDL and HDL cholesterol and low triglycerides. They are often lean and healthy people who present with strange and alarming lipid numbers after going on the ketogenic diet. Dave Feldman, Dr. Nick Norwitz & Dr. Dominic D’Agostino discuss the LMHR phenotype, whether it’s a concern, whether it’s rare, the Oreo vs statin study, how exercise levels might play a role, and why more research is needed. Sign Up to Get Your Free Ultimate Guide to Glucos...
May 31, 2024•2 hr 40 min•Ep 255•Transcript available on Metacast Writing an evidence-based nonfiction book requires time, dedication, and a true passion for the content. Dr. Casey Means and her brother Calley Means joined forces to create their book “Good Energy: The Surprising Connection Between Metabolism and Limitless Health.” Casey Means, MD, and Mike Haney discuss the book-writing process, insights into creativity and inspiration, the steps to seeking an agent and selling a book to a publisher, and the trials and tribulations along the way. Sign Up to Ge...
May 14, 2024•1 hr 25 min•Ep 254•Transcript available on Metacast Insulin resistance is when cells stop responding to insulin’s signal to uptake glucose. It’s a hallmark of prediabetes, Type 2 diabetes, and other forms of metabolic dysfunction, and it manifests as several chronic disease, ranging from Alzheimer’s to polycystic ovarian syndrome. Dr. Rob Lustig and Dr. Dominic D’Agostino discuss the importance of monitoring insulin levels, why a high or increasing insulin level is a problem, and how insulin resistance hinders weight management. Sign Up to Get Yo...
May 09, 2024•1 hr 17 min•Ep 253•Transcript available on Metacast The ketogenic diet is a low-carbohydrate, high-fat diet that has proven benefits for brain health. Research shows that the keto diet helps ease symptoms of some mental health conditions, including depression and bipolar disorder. But no diet, even keto, is one-size-fits all. Dr. Georgia Ede and Dr. Dominic D’Agostino discuss how diet and brain health are connected, how diet and gut health affect brain health, and how a ketogenic or other low-carbohydrate diets can be tailored to people’s specifi...
Apr 25, 2024•1 hr 15 min•Ep 252•Transcript available on Metacast Not all calories are equal. Tracking your macronutrient intake, using AI capabilities, can help you improve your body composition, facilitate weight loss, and boost exercise performance. The three macronutrients are protein, fat, and carbohydrates, with fiber a subset of carbs. Josh Clemente & Dr. Dominic D'Agostino discuss the new macros-tracking feature in the Levels app, the purpose and importance of each macronutrient, how to use macros-tracking in conjunction with biomarker data to ...
Apr 18, 2024•2 hr 47 min•Ep 251•Transcript available on Metacast Fructose and its byproduct uric acid may play a role in the development of Alzheimer’s, thanks to an evolutionary adaptation hijacked by the modern diet. Fructose can be directly consumed, or the body can convert high-glycemic carbohydrates and other foods to fructose. Fructose suppresses some cognitive functions. Dr. Richard Johnson and Dr. Rob Lustig discuss a new study, of which Johnson was an author, on how fructose may be a potential driver in Alzheimer’s, and they hypothesize about fructos...
Apr 11, 2024•1 hr 5 min•Ep 250•Transcript available on Metacast Gastrointestinal health, metabolic health, and fertility are all linked. The gut microbiome impacts other microbiomes in the body, which can then impact the ability to conceive. Our gut microbiomes are becoming less diverse through modern farming practices and the consumption of processed foods. Dr. Robin Rose and Ben Grynol discuss how gut microbiome testing can determine underlying factors of gastrointestinal distress and the lifestyle changes that can help address symptoms and even aid fertil...
Mar 28, 2024•57 min•Ep 249•Transcript available on Metacast High-carbohydrate diets and carbohydrate loading have been long-standing tenets of athletic training and competition, but newer research indicates a low-carbohydrate diet may be more beneficial for performance and overall health. Professor Tim Noakes and Josh Clemente discuss how a fat-adapted body can rely on fat as a fuel source at all exercise intensity levels, rather than burning mostly carbohydrates, and how such adaptation and dietary focus may reduce one’s risk of prediabetes and Type 2 d...
Mar 14, 2024•1 hr 3 min•Ep 248•Transcript available on Metacast Your sleep routine is one of the most important aspects of your metabolic health. Look for multiple new shows per week on A Whole New Level, where we have in-depth conversations about metabolic health and how the Levels startup team builds a wellness movement from the ground up in the health and wellness tech industry. Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl Levels helps you see how food affects your health, empowering you with the tools needed to achieve he...
Feb 29, 2024•25 min•Ep 250•Transcript available on Metacast Stable glucose levels are a foundation of feeling and looking your best at any age. When glucose levels are more erratic—with spikes and crashes—cravings, weight gain, low energy, health issues, and more can ensue. Jessie Inchauspé and Dr. Casey Means, thought leaders on the topic of blood sugar, discuss simple hacks for keeping glucose levels more stable without resorting to restrictive diets, and they share why stable levels inform health. Sign Up to Get Your Free Ultimate Guide to Glucose: ...
Feb 23, 2024•1 hr 21 min•Ep 246•Transcript available on Metacast Can a holistic protocol address the root cause of autoimmune diseases like multiple sclerosis (MS)? We explore how metabolic health is tightly linked to autoimmune diseases and how understanding blood sugar levels and insulin sensitivity is key. Dr. Terry Wahls developed The Wahls Protocol, which helped Dr. Wahls reverse her disease process and helped her get back on her feet. The Wahls Protocol is one of the most influential lifestyle programs that helps people address their autoimmune diseases...
Feb 08, 2024•1 hr 5 min•Ep 244•Transcript available on Metacast Traditional soft drinks, juice boxes, and energy and sports drinks are loaded with high fructose corn syrup, an ingredient also found in many processed foods. The body processes fructose differently than other sugars, and fructose can lead to weight gain by encouraging the body to store energy. Dr. Richard Johnson and Dr. Dominic D’Agostino discuss the issues with fructose, sucralose (found in PRIME energy drinks), and other artificial sweeteners. They explore how fructose can drive food craving...
Feb 02, 2024•1 hr 5 min•Ep 243•Transcript available on Metacast What are the unique metabolic health experiences of South Asian and Black communities? In this candid conversation between serial entrepreneur and health and wellness investor Dhru Purohit and content creator and metabolism mentor Austin McGuffie, they discuss how metabolic health affects their respective communities. Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl Levels helps you see how food affects your health, empowering you with the tools needed to achieve hea...
Jan 25, 2024•56 min•Ep 244•Transcript available on Metacast Highly processed food is hard to avoid. It’s especially harder when you’re a parent. For Austin McGuffie and Ben Grynol, they both have 4 kids, and they talk about the challenges of parenting, feeding kids nutritious food, and educating them along the way. Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to...
Jan 04, 2024•47 min•Ep 242•Transcript available on Metacast 
