“What good is half a wing?” That’s the rhetorical question often asked by people who have trouble accepting Darwin’s theory of evolution by natural selection. Of course it’s a very answerable question, but figuring out what exactly the answer is leads us to some fascinating biology. Neil Shubin should know: he is the co-discoverer of Tiktaalik Roseae , an ancient species of fish that was in the process of learning to walk and breathe on land. We talk about how these major transitions happe...
Mar 16, 2020•2 hr 33 min•Ep 88•Transcript available on Metacast If you tell me that one of the world’s leading neuroscientists has developed a theory of how the brain works that also has implications for the origin and nature of life more broadly, and uses concepts of entropy and information in a central way — well, you know I’m going to be all over that. So it’s my great pleasure to present this conversation with Karl Friston, who has done exactly that. One of the most highly-cited neuroscientists now living, Friston has proposed that we understand the brai...
Mar 09, 2020•2 hr 30 min•Ep 87•Transcript available on Metacast Anyone who has read histories of the Cold War, including the Cuban Missile Crisis and the 1983 nuclear false alarm, must be struck by how incredibly close humanity has come to wreaking incredible destruction on itself. Nuclear war was the first technology humans created that was truly capable of causing such harm, but the list of potential threats is growing, from artificial pandemics to runaway super-powerful artificial intelligence. In response, today’s guest Martin Ree...
Mar 02, 2020•2 hr 40 min•Ep 86•Transcript available on Metacast It’s hard to make decisions that will change your life. It’s even harder to make a decision if you know that the outcome could change who you are . Our preferences are determined by who we are, and they might be quite different after a decision is made — and there’s no rational way of taking that into account. Philosopher L.A. Paul has been investigating these transformative experiences — from getting married, to having a child, to going to graduate school — with an eye to deciding how to ...
Feb 24, 2020•1 hr 14 min•Ep 85•Transcript available on Metacast Nations generally want their economies to be rich, robust, and growing. But it’s also important to person to ensure that wealth doesn’t flow only to a few people, but rather that as many people as possible can enjoy the benefits of a healthy economy. As is well known, the best way to balance these interests is a contentious subject. On one side we might find free-market fundamentalists who want to let supply and demand set prices and keep government interference to a minimum, while on the other ...
Feb 17, 2020•1 hr 27 min•Ep 84•Transcript available on Metacast The Greek statesman Demosthenes is credited with saying “I am a citizen of the world,” and the idea that we should take a cosmopolitan view of our common humanity is a compelling one. Not everyone agrees, however; in the words of former British Prime Minister Theresa May, “If you are a citizen of the world, you are a citizen of nowhere.” On the other side of the political spectrum, groups who share a feature of identity — race, ethnicity, gender, sexuality, and others — find it useful to band to...
Feb 10, 2020•2 hr 39 min•Ep 83•Transcript available on Metacast The Convention on Psychotropic Substances was a 1971 United Nations treaty that placed strong restrictions on the use of psychedelic drugs — not only on personal use, but medical and scientific research as well. Along with restrictions placed by individual nations, it has been very difficult for scientists to study the effects of psychedelics on the brain, despite indications that they might have significant therapeutic potential. But this has gradually been changing, and researchers...
Feb 03, 2020•1 hr 18 min•Ep 82•Transcript available on Metacast People have always disagreed about politics, passionately and sometimes even violently. But in certain historical moments these disagreements were distributed without strong correlations, so that any one political party would contain a variety of views. In a representative democracy, that kind of distribution makes it easier to accomplish things. In contrast, today we see strong political polarization: members of any one party tend to line up with each other on a range of issues, and correspondi...
Jan 27, 2020•1 hr 22 min•Ep 81•Transcript available on Metacast Physics is simple; people are complicated. But even people are ultimately physical systems, made of particles and forces that follow the rules of the Core Theory. How do we bridge the gap from one kind of description to another, explaining how someone we know and care about can also be “just” a set of quantum fields obeying impersonal laws? This is a hard question that comes up in a variety of forms — What is the “self”? Do we have free will, the ability to make choices? What are the...
Jan 20, 2020•1 hr 27 min•Ep 80•Transcript available on Metacast We are all alive, but “life” is something we struggle to understand. How do we distinguish a “living organism” from an emergent dynamical system like a hurricane, or a resource-consuming chemical reaction like a forest fire, or an information-processing system like a laptop computer? There is probably no one crisp set of criteria that delineates life from non-life, but it’s worth the exercise to think about what we really mean, especially as the quest to find life outside the confines of the Ear...
Jan 13, 2020•1 hr 23 min•Ep 79•Transcript available on Metacast Wilfrid Sellars described the task of philosophy as explaining how things, in the broadest sense of term, hang together, in the broadest sense of the term. (Substitute “exploring” for “explaining” and you’d have a good mission statement for the Mindscape podcast.) Few modern thinkers have pursued this goal more energetically, creatively, and entertainingly than Daniel Dennett. One of the most respected philosophers of our time, Dennett’s work has ranged over topics such as consciousness, artific...
Jan 06, 2020•2 hr 2 min•Ep 78•Transcript available on Metacast Welcome to the second annual Mindscape Holiday Message! No substantive content or deep ideas, just me talking a bit about the state of the podcast and what’s on my mind. Since the big event for me in 2019 was the publication of Something Deeply Hidden , I thought it would be fun to talk about the process of writing and selling a popular book. Might be of interest to some of you out there! Mindscape takes off for the holidays, so the next regular episode will be published on Monday January ...
Dec 22, 2019•1 hr 6 min•Transcript available on Metacast In the United States, more than one in five deaths is caused by cancer . The medical community has put enormous resources into fighting this disease, yet its causes and best treatments continue to be a puzzle. Azra Raza has been on both sides of the patient’s bed, as she puts it — both as an oncologist and expert in the treatment of Myelodisplastic Syndrome (MDS), and as a wife who lost her husband to cancer. In her new book, The First Cell , she argues that we have placed too much e...
Dec 16, 2019•1 hr 22 min•Ep 77•Transcript available on Metacast It’s too easy to take laws of nature for granted. Sure, gravity is pulling us toward Earth today; but how do we know it won’t be pushing us away tomorrow? We extrapolate from past experience to future expectation, but what allows us to do that? “Humeans” (after David Hume, not a misspelling of “human”) think that what exists is just what actually happens in the universe, and the laws are simply convenient summaries of what happens. “Anti-Humeans” think that the laws have an existence of their ow...
Dec 09, 2019•1 hr 26 min•Ep 76•Transcript available on Metacast We've talked a lot recently about the Many Worlds of quantum mechanics. That’s one kind of multiverse that physicists often contemplate. There is also the cosmological multiverse, which we talked about with Brian Greene. Today’s guest, Max Tegmark, has thought a great deal about both of those ideas, as well as a more ambitious and speculative one: the Mathematical Multiverse, in which we imagine that every mathematical structure is real, and the universe we perceive is just one such mathematical...
Dec 02, 2019•1 hr 12 min•Ep 75•Transcript available on Metacast An infinite number of things happen; we bring structure and meaning to the world by making art and telling stories about it. Every work of literature created by human beings comes out of an historical and cultural context, and drawing connections between art and its context can be illuminating for both. Today’s guest, Stephen Greenblatt, is one of the world’s most celebrated literary scholars, famous for helping to establish the New Historicism school of criticism, which he also refers to as “cu...
Nov 25, 2019•1 hr 6 min•Ep 74•Transcript available on Metacast Changing technologies have always affected how we produce and enjoy art, and music might be the most obvious example. Radio and recordings made it easy for professional music to be widely disseminated, but created a barrier to its creation. Nowadays computers are helping to reverse that trend, allowing casual users to create slick songs of their own. Not everyone is equally good at it, however; Grimes (who currently goes by c , the symbol for the speed of light) is a wildly successful electronic...
Nov 18, 2019•1 hr 18 min•Ep 73•Transcript available on Metacast Maxwell's Demon is a famous thought experiment in which a mischievous imp uses knowledge of the velocities of gas molecules in a box to decrease the entropy of the gas, which could then be used to do useful work such as pushing a piston. This is a classic example of converting information (what the gas molecules are doing) into work . But of course that kind of phenomenon is much more widespread -- it happens any time a company or organization hires someone in order to take advantage of their kn...
Nov 11, 2019•1 hr 17 min•Ep 72•Transcript available on Metacast The human brain contains roughly 85 billion neurons, wired together in an extraordinarily complex network of interconnected parts. It’s hardly surprising that we don’t understand the mind and how it works. But do we know enough about our experience of consciousness to suggest that consciousness cannot arise from nothing more than the physical interactions of bits of matter? Panpsychism is the idea that consciousness, or at least some mental aspect, is pervasive in the world, in atoms and rocks a...
Nov 04, 2019•2 hr 35 min•Ep 71•Transcript available on Metacast Cosmologists are always talking excitedly about the Big Bang and all the cool stuff that happened in the 14 billion years between then and now. But what about the future? We don't know for sure, but we know enough about the laws of physics to sketch out several plausible scenarios for what the future of our universe will hold. Katie Mack is a cosmologist who is writing a book about the end of the universe. We talk about the possibilities of a Big Crunch (and potential Big Bounce), a gentle cooli...
Oct 28, 2019•1 hr 23 min•Ep 70•Transcript available on Metacast Like so many technological innovations, the internet is something that burst on the scene and pervaded human life well before we had time to sit down and think through how something like that should work and how it should be organized. In multiple ways — as a blogger, activist, fiction writer, and more — Cory Doctorow has been thinking about how the internet is affecting our lives since the very beginning. He has been especially interested in legal issues surrounding copyright, publishing, and f...
Oct 21, 2019•1 hr 18 min•Ep 69•Transcript available on Metacast Artificial intelligence is better than humans at playing chess or go, but still has trouble holding a conversation or driving a car. A simple way to think about the discrepancy is through the lens of “common sense” — there are features of the world, from the fact that tables are solid to the prediction that a tree won’t walk across the street, that humans take for granted but that machines have difficulty learning. Melanie Mitchell is a computer scientist and complexity researcher who has writte...
Oct 14, 2019•1 hr 22 min•Ep 68•Transcript available on Metacast Our observable universe started out in a highly non-generic state, one of very low entropy, and disorderliness has been growing ever since. How, then, can we account for the appearance of complex systems such as organisms and biospheres? The answer is that very low-entropy states typically appear simple, and high-entropy states also appear simple, and complexity can emerge along the road in between. Today’s podcast is more of a discussion than an interview, in which behavioral neuroscientist Kat...
Oct 07, 2019•1 hr 13 min•Ep 67•Transcript available on Metacast The idea of “red states” and “blue states” burst on the scene during the 2000 U.S. Presidential elections, and has a been a staple of political commentary ever since. But it’s become increasingly clear, and increasingly the case, that the real division isn’t between different sets of states, but between densely- and sparsely-populated areas. Cities are blue (liberal), suburbs and the countryside are red (conservative). Why did that happen? How does it depend on demographics, economics, and the p...
Sep 30, 2019•2 hr 53 min•Ep 66•Transcript available on Metacast We had our fun last week, exploring how progress in renewable energy and electric vehicles may help us combat encroaching climate change. This week we’re being a bit more hard-nosed, taking a look at what’s currently happening to our climate. Michael Mann is one of the world’s leading climate scientists, and also a dedicated advocate for improved public understanding of the issues. It was his research with Raymond Bradley and Malcolm Hughes that introduced the “hockey stick” graph, showing how g...
Sep 23, 2019•1 hr 17 min•Ep 65•Transcript available on Metacast The Earth is heating up, and it’s our fault. But human beings are not always complete idiots (occasional contrary evidence notwithstanding), and sometimes we can even be downright clever. Dare we imagine that we can bring our self-inflicted climate catastrophe under control, through a combination of technological advances and political willpower? Ramez Naam is optimistic, at least about the technological advances. He is a technologist, entrepreneur, and science-fiction author, who has been follo...
Sep 16, 2019•1 hr 17 min•Ep 64•Transcript available on Metacast I suspect most loyal Mindscape listeners have been exposed to the fact that I’ve written a new book, Something Deeply Hidden: Quantum Worlds and the Emergence of Spacetime . As I release this episode on Monday 9 September 2019, the book will officially be released tomorrow, in print, e-book, and audio versions. To get in the mood, we’ve had several podcast episodes on quantum mechanics, but the “emergence of spacetime” aspect has been neglected. So today we have a solo podcast ...
Sep 09, 2019•2 hr 50 min•Ep 63•Transcript available on Metacast Physicists study systems that are sufficiently simple that it’s possible to find deep unifying principles applicable to all situations. In psychology or sociology that’s a lot harder. But as I say at the end of this episode, Mindscape is a safe space for grand theories of everything. Psychologist Michele Gelfand claims that there’s a single dimension that captures a lot about how cultures differ: a spectrum between “tight” and “loose,” referring to the extent to which social norms are automatica...
Sep 02, 2019•1 hr 12 min•Ep 62•Transcript available on Metacast All of us have been wrong about things from time to time. But sometimes it was a simple, forgivable mistake, while other times we really should have been correct. Properties that systematically prevent us from being correct, and for which we can legitimately be blamed, are “intellectual vices.” Examples might include closed-mindedness, wishful thinking, overconfidence, selective attention, and so on. Quassim Cassam is a philosopher who studies knowledge in various forms, and who has recently wri...
Aug 26, 2019•1 hr 10 min•Ep 61•Transcript available on Metacast Memory takes different forms. Memories can be encoded in the strength of neural connections in our brains, but there’s a sense in which photographs and written records are memories as well. What did people do before such forms of memory even existed? Lynne Kelly is a science writer and researcher who specializes in forms of memory in the ancient world, as well as a competitive memory expert in her own right. She has theorized that ancient structures such as Stonehenge might have served as memory...
Aug 19, 2019•1 hr 16 min•Ep 60•Transcript available on Metacast 
