Precocious puberty | don't peak too soon

Precocious puberty is the early onset of puberty - which is prior to the age of 8 years in girls, and 9 years in boys. It is more common in girls than in boys, and it is important to remember that girls are much more likely to have idiopathic precocious puberty than boys are (boys experiencing precocious puberty are much more likely to have a pathological cause).

Precocious puberty can be split into central and peripheral. Central precocious puberty is gonadotropin dependent, meaning it is triggered by premature activation of the hypothalamic-pituitary-gonadal axis and release of gonadotropins from the brain, resulting in sex hormone production in the gonads. By contrast, peripheral precocious puberty is independent of gonadotropin, and is caused by sex hormone production in the gonads or adrenal glands.

You don’t want to miss:

• A case
• A quick revision of the normal process of puberty
• The difference between central and peripheral precocious puberty, and how this may be differentiated clinically 
• How precocious puberty may present
• The causes of precocious puberty
• Investigations to consider
• Treatment principles
• Complications of precocious puberty

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(This isn’t individual medical advice, please use your own clinical judgement and local guidelines when caring for your patients)