The supplement aisle seems to promise everything: rapid fat burning, appetite suppression, effortless weight loss. With billions of dollars spent annually and 60% of Americans taking supplements regularly, the questions are endless. Do they actually work? Are they safe? And how do you separate the science from the marketing hype? Join Holly and Jim as they tackle the complex world of weight loss supplements with one of the nation's leading experts. You'll discover why the supplement industry ope...
Oct 29, 2025•48 min•Ep. 98
You've got questions. Lots of them. And if you've been trying to lose weight or keep it off, chances are you've Googled these same burning questions at 11 p.m., desperately searching for answers that actually make sense. From "Do I really have to give up bread?" to "What do I do when the scale isn't moving?" - these are the questions that keep showing up in Holly and Jim's clinics, programs, emails, and even chance encounters at the grocery store. The questions that make you laugh, make you thin...
Oct 22, 2025•46 min•Ep. 97
"I just need more willpower." If you've ever said this to yourself, you're not alone. It's one of the most common beliefs in weight loss: that success comes down to having iron-clad self-control and the ability to resist every temptation that comes your way. But what if willpower isn't the secret weapon you think it is? What if, depending on it, is actually setting you up for failure? Holly and Jim are about to shatter one of the biggest myths in weight management and show you a completely diffe...
Oct 15, 2025•40 min•Ep. 96
I just love food too much. It's one of the most common excuses people give for not starting their weight loss journey. But what if loving food could actually be your secret weapon? Join Holly and Jim as they welcome David Page, the Emmy-winning creator of Diners, Drive-Ins, and Dives and host of the Culinary Characters Unlocked podcast. David has built his entire career around celebrating incredible food, yet he's managed to lose over 80 pounds without sacrificing his passion for eating. His sto...
Oct 08, 2025•43 min•Ep. 95
GLP1 medications have revolutionized weight loss, helping millions achieve results they've struggled to reach for years. These powerful tools have changed the obesity treatment landscape in ways we never imagined possible. But here's what might shock you: even with these game-changing medications, many people unknowingly sabotage their own success. The truth is, having access to effective weight loss medication is only half the battle. The other half? Knowing how to use these tools strategically...
Oct 01, 2025•45 min•Ep. 94
Fall is here, and with it comes one of the most challenging seasons for maintaining your weight loss progress. Shorter days, comfort food cravings, endless holiday gatherings, and disrupted routines create what Holly and Jim call "the perfect storm for weight gain." But what if this season didn't have to mean falling behind? Instead of throwing in the towel until January, you can use this time to actually move forward. The science shows that people typically gain 1-3 pounds during the fall and h...
Sep 24, 2025•43 min•Ep. 93
Think you know everything about working out? Most people hit the gym with good intentions, but miss a critical piece of the puzzle that could be sabotaging their results. The order you do your exercises, the type of resistance training you choose, and even how you think about protein could be the difference between building functional strength and just going through the motions. Join Holly and Jim as they welcome Professor Robin Daly from Deakin University in Melbourne, Australia. Robin holds th...
Sep 17, 2025•47 min•Ep. 92
When you're losing weight, you probably think about dropping dress sizes, improving blood sugar, or reducing joint pain. But what if some popular weight loss approaches could actually be setting you up for broken bones later in life? It's a connection most people never make and one that could change how you think about your weight loss journey. This hidden risk becomes even more important as new weight loss medications help people achieve dramatic results. While losing 30+ pounds can transform y...
Sep 10, 2025•50 min•Ep. 91
Ever felt like you're fighting a losing battle with hunger while trying to lose weight? You're cutting portions, counting calories, and white-knuckling your way through constant cravings. What if there was a smarter approach that didn't require superhuman willpower? The secret isn't eating less food, it's eating differently. Today's episode introduces you to one of the most powerful yet underutilized strategies in weight management: energy density. This science-backed approach shows you how to f...
Sep 03, 2025•45 min•Ep. 90
You've heard the weight loss success stories, but what about the hidden cost? While the scale drops, something precious might be disappearing too – your muscle. With the rise of GLP-1 medications helping millions shed pounds rapidly, a critical question emerges: are we losing the right kind of weight? The harsh reality is that for every pound you lose, up to 25% could be lean muscle mass. And here's the kicker – when you regain weight (which happens to most people), you don't get that muscle bac...
Aug 27, 2025•50 min•Ep. 89
Protein is everywhere these days. Walk down any grocery aisle and you'll see "high protein" splashed across cereal boxes, snack bars, and even ice cream. Scroll through social media, and influencers are preaching about protein powder. But with all this noise, what does the science actually say about protein's role in weight management? If you've ever wondered whether protein really lives up to the hype or if you're struggling with constant hunger, afternoon snacking, or hitting weight loss plate...
Aug 20, 2025•46 min•Ep. 88
Aging is inevitable, but how fast it happens isn't. This episode will open your eyes to the powerful connections between weight management and healthy aging. You might think aging is largely out of your control, determined by genetics and luck. But what if we told you that you have far more influence over your aging process than you might imagine? And what if the weight management strategies you're using now could be the key to not just living longer, but living better with sharper minds, strong...
Aug 13, 2025•42 min•Ep. 87
Ever wonder why the same diet that helped your friend lose 20 pounds left you frustrated and unchanged? You're not alone. The truth is, our bodies aren't built with a one-size-fits-all playbook, and the science is finally catching up to what many of us have suspected all along. Join Holly and Jim as they delve deep into the revolutionary world of personalized nutrition with Dr. Beth Mayer-Davis, a leading researcher who's helping to reshape how we think about diet and weight loss. Dr. Beth is th...
Aug 06, 2025•50 min•Ep. 86
Most people know that carrying extra weight affects their heart and blood sugar, but what if we told you it's also one of the biggest cancer risk factors you can actually control? The connection between obesity and cancer is stronger than most realize, yet it's also one of the most empowering discoveries in modern medicine. Join Holly and Jim as they welcome Dr. David Heber, a true pioneer in nutrition research who founded the UCLA Center for Human Nutrition when few were exploring this critical...
Jul 30, 2025•49 min•Ep. 85
When your weight loss plateaus don't make sense, when your labs are worse than expected, or when your clothes fit better but the scale won't budge, there might be an invisible culprit working against you. Low-grade inflammation isn't just about sore throats or swollen joints. It's a silent saboteur that can reshape how your fat cells function, how your body responds to insulin, and how your metabolism adapts to change. But here's the empowering truth: inflammation isn't something that just happe...
Jul 23, 2025•43 min•Ep. 84
Think fiber is just something your grandmother nagged you about? Think again. This overlooked nutritional powerhouse might be the secret weapon you've been missing in your weight loss journey. While most people focus on cutting calories and restricting foods, there's one nutrient that experts are practically begging you to eat MORE of – and it could transform how you feel, how much you eat, and how successfully you maintain your weight. Join Holly and Jim as they sit down with the world's leadin...
Jul 16, 2025•45 min•Ep. 83
Does this sound familiar? You're crushing it all week long with your healthy habits, feeling motivated and on track. Then Friday night rolls around and suddenly it's like a switch flips. By Sunday evening, you're promising yourself you'll "start fresh on Monday" while polishing off that leftover pizza. If you've ever felt trapped in the cycle of weekday wins followed by weekend wreckage, you're definitely not alone. Join Holly and Jim as they tackle one of the most common patterns that derail we...
Jul 09, 2025•37 min•Ep. 82
Artificial intelligence is revolutionizing everything from how we shop to how we work—but can it actually help you lose weight and keep it off? While AI coaches promise 24/7 support and personalized guidance, the technology is still in its infancy with plenty of pitfalls to navigate. Join Holly and Jim as they explore the exciting frontier of AI in weight management with Dr. Diana Thomas, a mathematician turned obesity researcher who stands at the forefront of this technological revolution. Dr. ...
Jul 02, 2025•49 min•Ep. 81
You can have the perfect meal plan, unwavering motivation, and the best intentions in the world—but if your grocery cart is filled with the wrong foods, the weight loss game might already be over before you even get home. The truth is, grocery shopping is the front line of behavior change, and most people are making critical mistakes that sabotage their success without even realizing it. Join Holly and Jim as they welcome registered dietitian Kelly Berg, who runs the metabolic kitchen at UAB's D...
Jun 25, 2025•43 min•Ep. 80
The weight loss world has been turned upside down. With GLP-1 medications like Ozempic and Wegovy delivering unprecedented results, many people are asking: Do we still need to worry about diet and exercise? Can these powerful drugs really do all the heavy lifting, or are we missing something crucial? This question isn't just academic - it's personal for millions of people who are either on these medications or considering them. The stakes are high: get it wrong, and you could be setting yourself...
Jun 18, 2025•46 min•Ep. 79
Menopause and weight gain - two words that strike fear into the hearts of millions of women. But what if everything you've been told about inevitable weight gain during menopause isn't the whole story? What if there are strategies, backed by cutting-edge research, that can help you navigate this transition without accepting defeat? Join Holly and Jim as they tackle one of their most requested topics with not one, but two powerhouse experts. Dr. Nanette Santoro, a leading authority in women's hea...
Jun 11, 2025•47 min•Ep. 78
Can you tell the difference between weight loss fact and fiction? With so much conflicting information floating around on social media and in conversations, it's easy to believe ideas that sound right but may actually be holding you back. Join Holly and Jim for a fun, eye-opening game of "Myth vs. Truth: Weight Loss Edition," where they tackle 10 of the most common claims about weight loss, metabolism, and exercise. You'll discover which widely-held beliefs are actually false, which have element...
Jun 04, 2025•37 min•Ep. 77
Are you struggling to maintain your weight loss results long-term? The missing ingredient might not be what you think. Forget about another new diet or workout routine - this episode dives into something potentially more powerful: your mind state. Join Holly and Jim as they introduce a revolutionary concept they've developed through years of working with successful weight maintainers. Discover how shifting from a "victim" mindset to a "victor" mindset is just the beginning, and how cultivating a...
May 28, 2025•46 min•Ep. 76
Summer has a way of throwing structure out the window. The longer days, vacations, kids out of school, and spontaneous social events can quickly derail your weight management habits, leaving you completely off track and frustrated by August. But what if this summer could be different? What if you could enjoy all the freedom and fun of the season while maintaining your healthy habits? The key lies in establishing intentional routines and rituals that anchor you during these months of unpredictabi...
May 21, 2025•35 min•Ep. 75
Are you on GLP-1 weight loss medications but struggling with side effects or nutrition concerns? Many people find that while these medications help shed pounds, they also create new challenges—from reduced appetite to difficulty enjoying foods you once loved. Join Holly and Jim as they interview nutrition expert Joan Salge-Blake, a registered dietitian, Boston University professor, and host of the popular "Spot On!" podcast. In this episode, they explore how these game-changing medications alter...
May 14, 2025•46 min•Ep. 74
Ever wonder if your evening glass of wine is sabotaging your weight loss? The relationship between alcohol and weight management is more complex than you might think. Many of us assume alcohol is the enemy of weight loss, but the science reveals some surprising findings. Join Holly and Jim as they tackle the often-asked question: "Can I drink alcohol and still lose weight?" They dive into the research and discover that the connection between moderate alcohol consumption and weight is more nuance...
May 07, 2025•34 min•Ep. 73
Did you know there's a new way doctors may diagnose obesity? For decades, obesity has been defined simply by your BMI number, but leading experts are now proposing a more comprehensive approach that looks beyond just weight and height. Join Holly and Jim as they welcome Dr. Eric Ravussin, a renowned physiologist from the Pennington Biomedical Research Center who has spent over 40 years studying human metabolism and weight regulation. They explore how this new obesity definition could transform t...
Apr 30, 2025•50 min•Ep. 72
Intermittent fasting has become one of the most popular weight loss strategies but does it work better than traditional calorie restriction? This burning question finally has an answer, thanks to a groundbreaking year-long clinical trial. Join Holly and Jim as they interview Victoria Catenacci, the lead researcher behind this landmark study on 4:3 intermittent fasting. As a physician and clinical researcher at the University of Colorado Anschutz Medical Campus, Dr. Catenacci has spent years inve...
Apr 23, 2025•45 min•Ep. 71
Are you moving enough? While many of us focus on weight loss goals, we're often missing a critical piece of the puzzle: our drastic decline in daily movement. In this episode, Holly and Jim reveal how physical activity has quietly disappeared from our lives over the past decades. Did you know that in the 1960s, people burned 300-400 more calories daily without ever setting foot in a gym? Join Holly and Jim as they explore America's "physical activity report card" and share startling statistics a...
Apr 16, 2025•46 min•Ep. 70
Are you frustrated by conflicting weight loss advice? Tired of hearing about miracle diets and quick fixes that never seem to work? Get ready for a conversation that cuts through the noise and gets to the heart of weight management. In this episode, we're diving deep into the science of energy balance with Dr. Keith Frayn, Emeritus Professor of Human Metabolism at the University of Oxford. Dr. Frayn brings decades of research experience and a refreshingly clear perspective to one of the most con...
Apr 09, 2025•46 min•Ep. 69