What if it was possible to speed up drug development without having to reinvent the wheel? By repurposing existing drugs, drug hunters are taking a giant step forward towards changing the future of drug discovery. Join our panel of drug hunters to hear how they reinvent previously approved drugs to get a head start towards treating patients. Acknowledgements: Hosted by: Chris Garcia Narrated by: Gina Mullane and Chris Garcia Special thanks to: Ian Waddell Vad Lazari Barbara Killian...
Jun 15, 2021•31 min•Season 2Ep. 10
What if the cure for your untreatable disease was just waiting on the shelf at your neighborhood pharmacy? Join physician, patient, and researcher Dr. David Fajgenbaum as he shares how his unexpected battle with Castleman disease set him on a journey to find his cure and develop new ways of using existing drugs. Acknowledgements: Hosted by: Chris Garcia Narrated by: Gina Mullane Special thanks to: Dr. David Fajgenbaum Barbara Killian...
May 18, 2021•46 min•Season 2Ep. 9
The discovery of limulus amebocyte lysate (LAL) in the blood of horseshoe crabs has forever changed bacterial endotoxin testing. Today, researchers continue to look for any way they can protect these seafaring creatures while refining testing methods to decrease the need for animals. Join our panel for an in-depth look at how they’re working with legislators to preserve the horseshoe crab population and how LAL testing is the safest in vitro method to detect harmful bacteria. Acknowledgements: H...
Apr 20, 2021•44 min•Season 2Ep. 8
Three-dimensional cell models are primed to play a vital role in the future of drug development. By recreating tissue that mimics human systems, scientists can monitor disease progression and evaluate the effects of drug candidates. Join Drs. Elizabeth Anderson and Ian Waddell as they explain the evolution of biologic modeling and how 3D cell models are being used to develop effective therapeutics to patients. Acknowledgements: Hosted by: Gina Mullane Narrated by: Chris Garcia Special thanks to:...
Mar 16, 2021•29 min•Season 2Ep. 7
Within the past decade, CRISPR/Cas9 gene editing of mammalian cells has become common practice, but does it hold the key to unlocking future of therapeutic development? Join Dr. David Fischer and our panel for a detailed look at the advantages and applications of this Nobel Prize-winning technology. Acknowledgements: Hosted by: Gina Mullane Narrated by: Chris Garcia Special thanks to: Dr. David Fischer
Feb 16, 2021•27 min•Season 2Ep. 6
Get your four-part dose of vaccine…information, that is. In this brief recap, Vital Science hosts Gina Mullane and Chris Garcia chat about the content of our first several Season 2 episodes – a miniseries covering infectious disease and immunity, origins of vaccination, therapeutic development and regulation, and the scientific community’s recent accomplishments in the fight against COVID. Download individual episodes: See what you might have missed in the vaccine series or download and save ind...
Jan 19, 2021•3 min•Season 2Ep. 5
Recent developments in the race to develop a COVID vaccine show promise, but the question remains – when will it become available to the general public? Dr. Sarah Gould returns for the fourth and final installment of our vaccine miniseries to examine where we stand with the development of COVID-19 vaccines and some lingering challenges that may hamper their final approval. Acknowledgements: Hosted by: Chris Garcia Narrated by: Gina Mullane Special thanks to: Dr. Sarah Gould...
Dec 15, 2020•20 min•Season 2Ep. 4
“Accelerating” a vaccine for COVID-19 has piqued the interest of many, but is it really possible to develop one quickly and safely? Join distinguished scientist Dr. Lauren Black as she dives into the typical mechanisms behind a vaccine and why it takes several years to deliver one safely to the general public. Acknowledgements: Hosted by: Chris Garcia Narrated by: Gina Mullane Special thanks to: Dr. Lauren Black
Nov 17, 2020•23 min•Season 2Ep. 3
When the immune system is compromised, people rely on vaccines to eliminate and inactivate the threat. However, the process with which this happens is anything but simple. Dr. Christina Satterwhite joins us to explain how the immune system works and how vaccines target harmful pathogens in the second installment of our series on vaccines. Acknowledgements: Hosted by: Chris Garcia Narrated by: Gina Mullane Special thanks to: Dr. Christina Satterwhite...
Oct 20, 2020•47 min•Season 2Ep. 2
Since 1796, vaccines have helped humans combat smallpox, the flu, and other infectious diseases. The process of vaccine development has changed drastically since then, and is now front and center in the wake of COVID-19. In the first episode of our series on vaccines, join us as we talk with Dr. Sarah Gould about the history of vaccines and infectious disease. Acknowledgements: Hosted by: Chris Garcia Narrated by: Gina Mullane Special thanks to: Dr. Sarah Gould...
Sep 22, 2020•20 min•Season 2Ep. 1
Cate and Laura Cheevers are sisters who were both born with cystic fibrosis. Together, they’ve been through multiple clinical trials for genotype-specific treatments and continue to defy the odds. Hear their unique tales of growing up with this rare genetic disorder and how it’s shaped their lives today. Learn more about how the Cystic Fibrosis Foundation and Vertex Pharmaceuticals are working on treatments to aid those living with CF, and support Great Strides on their quest to find a cure for ...
Jul 21, 2020•42 min•Season 1Ep. 10
Dr. Guy Leclerc plays the role of both a researcher and a clinician, changing lives with his work on medical devices. Learn how his work directly improved the quality of life for a very special patient. Learn more about Isabelle’s story , and support what drives Dr. Leclerc by donating to the CHUM foundation . ACKNOWLEDGMENTS Hosted by: Gina Mullane Produced and Edited by: Meaghan Root and Ryan Stevenson Sound and Music by: David Coscia and Ryan Stevenson Special thanks to: Dr. Guy Leclerc, Isab...
Jun 16, 2020•35 min•Season 1Ep. 9
Jake Glanville, founding partner and CEO of Distributed Bio , has been featured in the Netflix series "Pandemic." Now, he and his team are on the front lines of the fight against COVID-19, working tirelessly to find a cure. Learn how his roots in Guatemala have shaped his beliefs on healthcare, how a family business has developed his skills as a leader, and how it all came together in his leadership of a talented, accomplished team of scientists. Read more about antibody discovery technologies a...
May 15, 2020•30 min•Season 1Ep. 8
Twins share many unique bonds, and for Jaci and Alex, fighting the same rare disease is one of them. Hear this emotional tale through the perspective of their mom, Lori, and their uncle, Mike, about how they have battled their illness, knowing the risks, and helped to develop a new treatment for this rare form of ALS. To learn more about Jaci’s story, please visit Cowgirl Up for Jaci: Roping in a CURE for ALS . For more information about ALS, please visit Project ALS . ACKNOWLEDGMENTS Hosted by:...
Apr 21, 2020•46 min•Season 1Ep. 7
College can take you many places. In the case of two neuroscience students, they didn’t know where their journey would take them. Their perseverance and fighting spirit built a company that aims to help those battling neurodegenerative diseases. See what Amylyx is working on .
Mar 17, 2020•36 min•Season 1Ep. 6
There are certain moments when life takes on a whole new meaning. For Allyson Berent, her daughter’s diagnosis with a rare genetic disorder gave her a purpose – to embark on the quest for a cure. Hear her remarkable journey from a veterinarian to the COO of GeneTx Biotherapeutics , and how partnering with Ultragenyx pharmaceutical fuels her determination to cure Angelman Syndrome. Learn more about FAST (Foundation for Angelman Syndrome Therapeutics)....
Feb 15, 2020•53 min•Season 1Ep. 5
What we experience can leave a lasting impact on our lives. In Carina’s case, her father’s diagnosis changed her career forever. Hear the emotional story of her ongoing fight to honor his memory and help others battling this rare neurodegenerative disease. Learn more about the Multiple System Atrophy Coalition
Jan 21, 2020•29 min•Season 1Ep. 4
Donnie Patterson is not just a pharmaceutical microbiologist. He’s also a victim of toxigenic mold, a growing problem in South Carolina schools. Hear how his story exposed an issue that led to his ongoing fight for tougher mold testing regulations. Visit the Global Indoor Health Network website for more information on toxic mold.
Dec 17, 2019•41 min•Season 1Ep. 3
Mila’s groundbreaking treatment, the first created and approved for a single patient, has given hope to thousands of rare-disease patients around the world. Hear Julia Vitarello, Mila’s Mom, and Dr. Timothy Yu discuss their plans to help other children with rare disease. Watch the documentary and learn more about Mila’s story at: www.criver.com/everystep In partnership with Mila’s Miracle Foundation, we are on a mission to bring this new treatment path to children fighting rare diseases. An anon...
Nov 19, 2019•49 min•Season 1Ep. 2
Mila is a young girl fighting Batten Disease, a rare, fatal disease with no cure. Her Mom, Julia Vitarello sits down with Gina to tell the story of Mila’s diagnosis and her incredible journey since; from diagnosis to Mila’s experimental genetic treatment, created just for her. Watch the documentary and learn more about Mila’s story at www.criver.com/everystep . Hosted by: Gina Mullane and Chris Garcia Produced by: Meaghan Root, Ryan Stevenson Sound and Music by: Ryan Stevenson Special thanks to:...
Oct 22, 2019•44 min•Season 1Ep. 1
Meet our hosts Gina Mullane and Chris Garcia as they introduce Vital Science™, a brand new podcast that shares the personal stories of those impacted by life science. Subscribe so you don't miss us, starting October 2019. ACKNOWLEDGMENTS Hosted by: Gina Mullane and Chris Garcia Produced by: Meaghan Root and Ryan Stevenson Sound and Music by: Ryan Stevenson
Sep 26, 2019•1 min
