Unsupervised Learning with Jacob Effron - podcast cover

Unsupervised Learning with Jacob Effron

We probe the sharpest minds in AI in search for the truth about what’s real today, what will be real in the future and what it all means for businesses and the world. If you’re a builder, researcher or investor navigating the AI world, this podcast will help you deconstruct and understand the most important breakthroughs and see a clearer picture of reality. Follow this show and consider enabling notifications to stay up to date on our latest episodes. Unsupervised Learning is a podcast by Redpoint Ventures, an early-stage venture capital fund that has invested in companies like Snowflake, Stripe, and Mistral. Hosted by Redpoint investor Jacob Effron alongside Patrick Chase, Jordan Segall and Erica Brescia.
Last refreshed:
Download Metacast podcast app
Podcasts are better in Metacast mobile app
Don't just listen to podcasts. Learn from them with transcripts, summaries, and chapters for every episode. Skim, search, and bookmark insights. Learn more

Episodes

Ep 89: AI Research Legend’s Honest Assessment of Where We Are

This episode with Lukasz Kaiser, co-author of the seminal "Attention Is All You Need" transformer paper and former researcher at both Google Brain and OpenAI, is a wide-ranging conversation about the fundamental limits of current AI architectures and whether transformers will continue to dominate or eventually give way to something new. Lukasz brings a rare dual perspective: deep belief in how far the current paradigm has taken us (he's an enthusiastic daily Codex user who's seen 10x productivit...

Jun 03, 20261 hr 14 minEp. 89

Ep 88: Unpacking DeepMind's Quest for SuperIntelligence with Demis Hassabis' Biographer

Sebastian Mallaby spent three years and 30+ hours interviewing Demis Hassabis in the back of a British pub to write The Infinity Machine , and the conversation uses that reporting to surface the most underexplored figure in AI. Demis founded the original AI lab in 2010, won a Nobel Prize, runs models that consistently top the leaderboards, and yet remains so unrecognized that Sebastian's own publisher worried no one would buy a book with his face on the cover. The throughline is a paradox: Demis...

Jun 01, 202656 minEp. 88

Ep 87: Gemini Co-Lead on World Models, RL's Next Domains & Continual Learning

Oriol Vinyals, VP of Research at Google DeepMind and co-lead of the Gemini program, joins Jacob the day after Google I/O to unpack the research underpinning Google's latest announcements and where frontier AI is heading. The conversation moves from world models (why Google has uniquely bet on them as a path to AGI, what the "GPT moment" for video and images would look like, and how they connect to robotics and simulation) to agents (the Spark release, why the system and model need to be optimize...

May 22, 20261 hrEp. 87

Ep 86: Yann LeCun on Leaving Meta, Breaking The LLM Paradigm, & Why Hinton is Wrong

Yann LeCun, Turing Award winner and former Chief AI Scientist at Meta, joins Jacob Effron. The conversation centers on Yann's contrarian thesis that LLMs are a dead-end on the path to human-level intelligence, despite being useful products — because they can't predict the consequences of their actions, can't plan, and fundamentally can't model the messy, high-dimensional real world. He unpacks his alternative architecture, JEPA (Joint Embedding Predictive Architecture), which learns abstract rep...

May 15, 20261 hr 22 minEp. 86

Ep 85: Has AI Infra Stabilized, FM Vibe Shift, & What's Next for Coding Agents

This episode is a wide-ranging conversation between Jacob and Swyx (Shawn Wang), an AI engineer, podcaster, and now operator at Cognition, who sits at a uniquely informed intersection of builder, investor, and community organizer in the AI world. The two cover the current state of the AI engineering zeitgeist: from the stabilization of agent infrastructure and the surprising stickiness of Claude Code, to the competitive dynamics of the AI coding wars, the rise of open models, the threat to tradi...

Apr 23, 202655 minEp. 85

Ep 84: OpenAI’s Chief Scientist on Continual Learning Hype, RL Beyond Code, & Future Alignment Directions

Jakub Pachocki, OpenAI's Chief Scientist, sits down with Jacob to cover the full arc of where AI research stands today and where it's headed. The conversation spans the explosive growth of coding agents and what it signals about near-term AI capability, the use of math and physics benchmarks as proxies for general intelligence, how reinforcement learning is being extended beyond easily-verified domains toward longer-horizon tasks, and what it means to run a research organization at the precise m...

Apr 09, 202659 minEp. 84

Ep 83: Owning the System of Record, AI-Native Org Charts, & Why ITSM is The Most Vulnerable Legacy Category

Jake Stauch, Serval's CEO, shares insights into building one of the fastest-growing AI-native enterprise software companies. He explains their contrarian bet on a full system of record for ITSM, arguing its unique vulnerability to AI disruption compared to CRM or ERP. The discussion covers Serval's innovative use of AI for code generation in automations, strategies for outmaneuvering large incumbents, and a talent-first approach to team building. Stauch also offers his vision for the future of enterprise software, management structures, and the evolving role of AI agents.

Apr 02, 202654 minEp. 83

Ep 82: Behind Legora's $550M Raise, Model Competition, Doubling Revenue Every Quarter, & US Expansion

Max Jungestål, CEO of Legora, joins Jacob Effron and Logan Bartlett to discuss the company's $550M Series D and share a candid account of what building an AI-native company at speed actually looks like from the inside. Max argues that the AI application layer requires a fundamentally different operating model than traditional SaaS, one built on low ego, constant reinvention, and a willingness to watch nine months of work get washed away by a model update. He walks through how step-function impro...

Mar 11, 202654 minEp. 82

Ep 81: Ex-OpenAI Researcher On Why He Left, His Honest AGI Timeline, & The Limits of Scaling RL

This episode features Jerry Tworek, a key architect behind OpenAI's breakthrough reasoning models (o1, o3) and Codex, discussing the current state and future of AI. Jerry explores the real limits and promise of scaling pre-training and reinforcement learning, arguing that while these paradigms deliver predictable improvements, they're fundamentally constrained by data availability and struggle with generalization beyond their training objectives. He reveals his updated belief that continual lear...

Jan 29, 20261 hr 3 minEp. 81

AI Vibe Check: The Actual Bottleneck In Research, SSI’s Mystique, & Spicy 2026 Predictions

Ari Morcos and Rob Toews return for their spiciest conversation yet. Fresh from NeurIPS, they debate whether models are truly plateauing or if we're just myopically focused on LLMs while breakthroughs happen in other modalities. They reveal why infinite capital at labs may actually constrain innovation, explain the narrow "Goldilocks zone" where RL actually works, and argue why U.S. chip restrictions may have backfired catastrophically—accelerating China's path to self-sufficiency by a decade. T...

Dec 18, 20251 hr 18 min

Ep 80: CEO of Surge AI Edwin Chen on Why Frontier Labs Are Diverging, RL Environments & Developing Model Taste

Edwin Chen is the founder and CEO of Surge AI, the data infrastructure company behind nearly every major frontier model. Surge works with OpenAI, Anthropic, Meta, and Google, providing the high-quality data and evaluation infrastructure that powers their models. Edwin reveals why optimizing for popular benchmarks like LMArena is "basically optimizing for clickbait," how one frontier lab's models regressed for 6-12 months without anyone knowing, and why the industry's approach to measurement is f...

Dec 15, 202548 minEp. 80

Ep 79: OpenAI's Head of Product on How the Best Teams Build, Ship and Scale AI Products

This episode features Olivier Godement, Head of Product for Business Products at OpenAI, discussing the current state and future of AI adoption in enterprises, with a particular focus on the recent releases of GPT 5.1 and Codex. The conversation explores how these models are achieving meaningful automation in specific domains like coding, customer support, and life sciences: where companies like Amgen are using AI to accelerate drug development timelines from months to weeks through automated re...

Dec 10, 202556 minEp. 79

Ep 78: Jordan Schneider, Host of China Talk, on AI Race, Key Policy Decisions & Unpacking Geopolitical Chip Tension

This week on Unsupervised Learning, Jacob Effron is joined by Jordan Schneider, host of China Talk, who challenges widespread assumptions about US-China AI competition. China's AI development is driven by private capital and market competition—not central government planning—with companies like DeepSeek, Alibaba, and ByteDance operating more like Silicon Valley startups than state projects. The critical bottleneck is compute: the West maintains a 10-15x advantage in advanced chips, and US export...

Dec 05, 20251 hr 13 minEp. 78

Ep 77: Anthropic’s Dianne Na Penn on Opus 4.5, Rethinking Model Scaffolding & Safety as a Competitive Advantage

This episode features Dianne Na Penn, a senior product leader at Anthropic, discussing the launch of Claude Opus 4.5 and the evolution of frontier AI models. The conversation explores how Anthropic approaches model development—balancing ambitious capability roadmaps with user feedback, making strategic bets on areas like agentic coding and computer use while deliberately avoiding others like image generation. Dianne shares insights on the shifting nature of AI evaluation (moving beyond saturated...

Dec 02, 202542 minEp. 77

Ep 76: Sora Creators Bill Peebles, Rohan Sahai & Thomas Dimson on Their Unexpected Viral Success

This episode features the core team behind Sora, OpenAI's groundbreaking video generation platform that became the #1 app in the App Store. Bill Peebles (research lead), Rohan Sahai (product lead), and Thomas Dimson (engineering/product lead with Instagram background) discuss the unexpected viral success of Sora's launch, the product journey that led to the breakthrough "cameo" feature (putting yourself in AI-generated videos), and their philosophy of building a creator-first social network that...

Nov 03, 20251 hr 3 minEp. 76

AI Round Up: Ari Morcos from Datalogy AI and Rob Toews from Radical VC on Karpathy Reactions, OpenAI’s Dealmaking, & Bubble Reality Check

This episode features Rob Toews from Radical Ventures and Ari Morcos, Head of Research at Datology AI, reacting to Andrej Karpathy's recent statement that AGI is at least a decade away and that current AI capabilities are "slop." The discussion explores whether we're in an AI bubble, with both guests pushing back on overly bearish narratives while acknowledging legitimate concerns about hype and excessive CapEx spending. They debate the sustainability of AI scaling, examining whether continued p...

Oct 24, 20251 hr 17 min

AI Round Up: Ari Morcos from Datalogy AI and Rob Toews from Radical VC on AI Talent Wars, xAI’s $200B Valuation, & Google’s Comeback

This episode features a deep dive into the current state of AI model progress with Ari Morcos (CEO of Datalogy AI and former DeepMind/Meta researcher) and Rob Toews (partner at Radical Ventures). The conversation tackles whether model progress is genuinely slowing down or simply shifting into new paradigms, exploring the role of reinforcement learning in scaling capabilities beyond traditional pre-training. They examine the talent wars reshaping AI labs, Google's resurgence with Gemini, the sust...

Sep 24, 20251 hr 3 min

Ep 75: Nano Banana’s Oliver Wang and Nicole Brichtova - Behind the Breakthrough as Gemini Tops the Charts

Fill out this short listener survey to help us improve the show: https://forms.gle/bbcRiPTRwKoG2tJx8 This week on Unsupervised Learning, Jacob sits down with Nicole Brichtova and Oliver Wang, the Google researchers behind "Nano Banana" - the breakthrough AI image model that achieved unprecedented character consistency and took over social media. The conversation covers how their model fits into creative workflows, why we're still in the early innings of image AI development despite impressive cu...

Sep 17, 202541 minEp. 75

Ep 74: Chief Scientist of Together.AI Tri Dao On The End of Nvidia's Dominance, Why Inference Costs Fell & The Next 10X in Speed

Fill out this short listener survey to help us improve the show: https://forms.gle/bbcRiPTRwKoG2tJx8 Tri Dao, Chief Scientist at Together AI and Princeton professor who created Flash Attention and Mamba, discusses how inference optimization has driven costs down 100x since ChatGPT's launch through memory optimization, sparsity advances, and hardware-software co-design. He predicts the AI hardware landscape will shift from Nvidia's current 90% dominance to a more diversified ecosystem within 2-3 ...

Sep 10, 202559 minEp. 74

Ep 73: General Partner of Felicis Peter Deng on on AI Pricing Tactics, Reaction to GPT-5 & Why Voice is Underrated

In this episode, Jacob sits down with Peter Deng, General Partner at Felicis and former Product Leader at OpenAI, Facebook, and Uber. Peter shares his insider perspective on building ChatGPT Enterprise in just seven weeks and leading voice mode development at OpenAI. The conversation covers everything from why traditional SaaS pricing models are broken for AI products to how evals became the new product specs, the "AI under your fingernails" test for founding teams, and why current agents are ma...

Aug 26, 20251 hr 4 minEp. 73

Ep 72: Co-Founder of Chai Discovery Joshua Meier on 99% Faster Drug Discovery, BioTech’s AlphaGo Moment, Building Photoshop for Molecules

In this episode, Jacob sits down with Joshua Meier, co-founder of Chai Discovery and former Chief AI Officer at Absci, to explore the breakthrough moment happening in AI drug discovery. They discuss how the field has evolved through three distinct waves, with the current generation of companies finally achieving success rates that seemed impossible just years ago. The conversation covers everything from moving drug discovery out of the lab and into computers, to why AI models think differently t...

Aug 13, 202557 minEp. 72

Ep 71: CEO of TurboPuffer Simon Eskildsen on Building Smarter Retrieval, AI App Must-Have Features & Current State of Vector DBs

Fill out this short listener survey to help us improve the show: https://forms.gle/bbcRiPTRwKoG2tJx8 In this episode, Simon Eskildsen, co-founder and CEO of TurboPuffer, lays out a compelling vision for how AI-native infrastructure needs to evolve in an era where every application wants to connect massive amounts of context to large language models. He breaks down why traditional databases and even large context windows fall short—especially at scale—and why object-storage-native search is the i...

Jul 22, 202551 minEp. 71

Ep 70: Karol Hausman and Danny Driess (Physical Intelligence) Unpack the Most Recent Breakthroughs & Path to Generalist Robots

In this episode, Jacob sits down with Karol Hausman (Co-Founder) and Danny Driess (Research Scientist) from Physical Intelligence, two of the minds behind some of the most exciting advances in robotics. They unpack the last decade of progress in AI robotics, from early skepticism to the breakthroughs powering today’s generalist robot models. The conversation covers everything from folding laundry with robots to building scalable data pipelines, the limits of simulation, and what it’ll take to br...

Jul 08, 20251 hr 10 minEp. 70

Ep 69: Co-Founder of Databricks & LMArena on Current Eval Limitations, Why China is Winning Open Source and Future of AI Infrastructure

Ion Stoica helped define the modern data stack. Now he’s coming for AI evaluation. From co-founding Databricks and Anyscale to launching LMArena, Ion has shaped the infrastructure underlying some of the biggest shifts in computing. In this conversation, he unpacks what most people get wrong about model evaluation, the infrastructure challenges ahead for agents and heterogeneous compute, and why he believes the U.S. is structurally disadvantaged in open-source AI compared to China. (0:00) Intro (...

Jun 17, 202555 minEp. 69

Ep 68: CEO of Mercor Brendan Foody on Evals Replacing Knowledge Work, AI x Hiring Today & the Future of Data Labeling

Brendan Foody is the co-founder and CEO of Mercor, a company building the infrastructure for AI-native labor markets. Mercor’s platform is already used by top AI labs to label data, evaluate human and AI candidates, and make performance-driven hiring decisions. They’re operating at the intersection of recruiting, evals, and foundation model development—helping companies shift from intuition to measurable prediction. Brendan and his team recently raised $100M and are working with some of the most...

Jun 04, 202544 minEp. 68

Ep 67: Max Junestrand (CEO, Legora) on Differentiating and Pricing AI Apps & How the Legal Industry Will Evolve

Max Junestrand, CEO of Legora, explores the rapid evolution and application of AI in the legal sector, from automating basic tasks to transforming complex workflows. He delves into Legora's journey, focusing on their unique approach to product development, market expansion from the Nordics, and managing the challenges of user adoption and pricing in a fast-changing AI landscape. The discussion also touches on critical strategic decisions like building vs. leveraging foundational models and the essential skills for future legal professionals.

May 27, 202544 minEp. 67

Ep 66: Member of Technical Staff at Anthropic Sholto Douglas on Claude 4, Next Phase for AI Coding, and the Path to AI Coworkers

Sholto Douglas, a Member of Technical Staff at Anthropic, joined Unsupervised Learning to break down why coding is the clearest early signal of model progress, how AI agents are already accelerating research, and what it’ll take to unlock real-world breakthroughs in fields like biology and robotics. (0:00) Intro (0:48) Claude 4 (1:30) Capabilities and Improvements (2:29) Practical Applications and Advice (3:04) Future of AI in Coding (4:38) Managing Multiple AI Models (11:20) The Barrier to Agen...

May 22, 202558 minEp. 66

Ep 65: Co-Authors of AI-2027 Daniel Kokotajlo and Thomas Larsen On Their Detailed AI Predictions for the Coming Years

The recent AI 2027 report sparked widespread discussion with its stark warnings about the near-term risks of unaligned AI. Authors @Daniel Kokotajlo (former OpenAI researcher now focused full-time on alignment through his nonprofit, @AI Futures, and one of TIME’s 100 most influential people in AI) and @Thomas Larsen joined the show to unpack their findings. We talk through the key takeaways from the report, its policy implications, and what they believe it will take to build safer, more aligned ...

May 14, 20251 hr 23 minEp. 65

Ep 64: GPT 4.1 Lead at OpenAI Michelle Pokrass: RFT Launch, How OpenAI Improves Its Models & the State of AI Agents Today

OpenAI's Michelle Pokrass shares insights into GPT-4.1, detailing its focus on real-world developer utility through user feedback and specialized evaluations, improving instruction following and long context. She explains the current state of AI agents, highlighting the power of fine-tuning (especially RFT) for pushing model frontiers in niche and deep tech domains. The discussion also covers strategies for developers to stay ahead of rapid AI progress, model selection, and future research directions at OpenAI.

May 08, 202547 minEp. 64

Ep 63: Khan Academy Founder/CEO on Salman Khan on Classrooms in 20 years, Rolling out to 1.4M Users & Sal’s Hopes for AI Education

Salman Khan, founder of Khan Academy, shares insights on deploying AI tools like Khanmigo to 1.4 million users, transforming education. He details how AI enhances teacher planning, student engagement, and personalized learning, discusses the importance of proactive AI and managing error rates. The conversation also explores the broader challenges and global potential of AI in shaping future classrooms and learning environments.

Apr 29, 202551 minEp. 63
For the best experience, listen in Metacast app for iOS or Android