Vincent, Dickson, Rich, and Alan review cell proteins essential for entry of hepatitis C, Ebola, and measles viruses. Links for this episode: Niemann-Pick C1 is entry factor for HCV (Nature Med) Ebola virus entry requires Niemann-Pick C1 (Nature one , two ) Nectin-4 is measles virus epithelial receptor ( Nature , PLoS Pathogens ) An exit strategy for measles virus (Science) On this day in history TWiV on Facebook Letters read on TWiV 166...
Jan 15, 2012•1 hr 38 min
Vincent, Dickson, Rich, and Alan answer listener questions about XMRV, cytomegalovirus, latency, shingles vaccine, myxomavirus and rabbits, and more.
Jan 08, 2012•1 hr 42 min
Vincent, Alan, and Rich review ten compelling virology stories of 2011.
Jan 01, 2012•1 hr 39 min
Vincent, Dickson, Rich, and Alan review the 100 year old finding by Peyton Rous of a transmissible sarcoma of chickens, a discovery that ushered in the era of tumor virology.
Dec 25, 2011•1 hr 42 min
Vincent, Rich, and Alan continue Virology 101 with a discussion of transcription, the process of making mRNA from a DNA template.
Dec 18, 2011•1 hr 33 min
Vincent, Rich, Alan and Gabriel review the production of antibodies by B cells, and how high affinity antibodies are selected in the germinal centers of lymph nodes.
Dec 11, 2011•1 hr 58 min
The TWiV team speaks with Patrick Moore about his discovery, with Yuan Chang, of two human tumor viruses, Kaposi's sarcoma herpesvirus and Merkel cell polyomavirus.
Dec 04, 2011•1 hr 49 min
Vincent, Alan, and Rich review concern over an influenza H5N1 transmission experiment, and a new host defense protein against RNA viruses.
Nov 27, 2011•1 hr 20 min
Vincent and Rich visit the Microbiology and Immunology Department at the University of Michigan Medical School, and speak with Alice and Kathy about their work on HIV genome dimerization, and packaging and pathogenesis of mouse adenovirus.
Nov 20, 2011•1 hr 27 min
A large TWiV panel remembers Ralph Steinman, and considers a new innate sensor of retroviral capsids.
Nov 14, 2011•2 hr 5 min
Vincent, Rich, and Dickson review a meta-analysis on influenza vaccine, a killer virus in fungi that selects against RNAi, and the use of armed and targeted poxviruses for oncolytic virotherapy.
Nov 05, 2011•1 hr 34 min
Vincent, Grant, Eurico, Paulo, Francisco and Janice discuss their work on bocavirus, infectious bronchitis virus, begamoviruses, and circoviruses at the Brazilian Virology Society meeting in Atibaia, São Paulo, Brazil.
Oct 30, 2011•1 hr 33 min
Vincent, Alan, and Rich are very enthusiastic about two studies that show how gut bacteria help viral invaders.
Oct 22, 2011•1 hr 17 min
Vincent, Alan, and Rich review an outbreak of rabies in arctic foxes and reindeer in Norway, and a prion that makes you go antiviral.
Oct 16, 2011•1 hr 32 min
Vincent, Alan, and Rich cover the virome of raw sewage, and a baculovirus gene that causes caterpillars to climb to their doom .
Oct 09, 2011•1 hr 23 min
Vincent, Alan, and Rich review questions and comments from TWiV listeners .
Oct 02, 2011•1 hr 21 min
Vincent, Dickson, and Rich meant to do an all-email episode, but first they review results of the Blood XMRV Scientific Research Working Group, and partial retraction of the paper associating XMRV with chronic fatigue syndrome .
Sep 24, 2011•1 hr 33 min
Vincent, Rich, Mark, and Trine discuss science and medicine in journalism and the eradication of poliovirus at the 51st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC).
Sep 17, 2011•1 hr 26 min
Vincent, Philip, David, and Priscilla recorded this episode before an audience at the Harvard Virology Program Annual Retreat, where they discussed negative strand RNA viruses, a vaccine against herpes simplex virus type 2, lipidomics of viral infection, and science communication.
Sep 11, 2011•1 hr 17 min
The complete TWiV gang discusses the use of Wolbachia to control mosquito-borne infections .
Sep 04, 2011•1 hr 29 min
Vincent, Rich, and Abbie review a broad spectrum antiviral protein, and selective pressure applied by a failed HIV-1 vaccine.
Aug 28, 2011•1 hr 47 min
Alan and Rich tackle the discovery of bacteriophages, and treating influenza by calming the cytokine storm.
Aug 16, 2011•1 hr 27 min
Vincent, Rich, and Alan discuss live blogging of scientific meetings, the current outbreak of Hendra virus is Australia, and using zinc finger nucleases to make HIV-resistant CD4 cells.
Jul 31, 2011•1 hr 44 min
Vincent, Rich, Julie and Stacey recorded TWiV at the 30th Annual Meeting of the American Society for Virology in Minneapolis, where they discussed the role of neutralizing antibodies in protection against HIV-1 infection, and astroviruses, agents of gastroenteritis.
Jul 24, 2011•1 hr 6 min
Vincent, Rich, and Alan discuss a method for identifying viruses of individual environmental bacteria, and the using a picornavirus for oncotherapy.
Jul 17, 2011•1 hr 35 min
Matt Evans joins Vincent, Dickson, Alan, and Rich to deconstruct a mouse model for hepatitis C virus infection.
Jul 10, 2011•1 hr 37 min
Vincent, Alan, Rich, and Judy Lieberman review the use of CD4 aptamer-siRNA chimeras to inhibit HIV transmission.
Jul 03, 2011•1 hr 32 min
Vincent, Alan, and Dickson discuss the reduction in genome size of Mimivirus upon passage in amoeba, and analysis of the microbiome of honeybees.
Jun 26, 2011•1 hr 20 min
Vincent meets up with Raul Andino in San Francisco to discuss the RNAi-based antiviral defense system of Drosophila , the fruit fly, and how it is antagonized by viruses.
Jun 19, 2011•1 hr 13 min
The TWiV team speaks with Amit Kapoor and Ian Lipkin about how they discovered canine hepacivirus, and its implications for the origin and evolution of hepatitis C virus.
Jun 12, 2011•1 hr 36 min
