On episode #99 of the podcast This Week in Virology , Vincent tours the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), speaking with exhibitors and visitors, including Professors Derek Smith , Michael Schmidt , Frederick Hayden , and Myra McClure . Host links Vincent Racaniello Links for this episode: 50th ICAAC ICAAC daily press conference videos (including Prof. Myra McClure ) Antigenic cartography Antimicrobial properties of copper...
Sep 20, 2010•1 hr 2 min
On episode #98 of the podcast This Week in Virology , Vincent, Alan, and Rich review the finding of murine leukemia virus-related sequences in the blood of CFS patients and healthy donors, laboratory inventories for wild poliovirus containment, weaving high-performance viral batteries into fabric for the military, and a case of human rabies in Indiana.
Sep 13, 2010•1 hr 21 min
On episode #97 of the podcast This Week in Virology , Vincent visited Peter Sarnow and Bert Semler during a trip to California, and spoke with them about their work on internal ribosome entry, and the requirement for a cellular microRNA for hepatitis C virus replication.
Sep 06, 2010•1 hr 32 min
On episode #96 of the podcast This Week in Virology , Vincent, Dickson, and Rich continue Virology 101 with a discussion of how viruses with DNA genomes replicate their genetic information.
Aug 22, 2010•1 hr 30 min
On episode #95 of the podcast This Week in Virology , Vincent, Dickson, Alan, and Rich consider the end of the influenza H1N1 pandemic, dengue in Florida, vaccinia virus infection in Brazilian monkeys, and viruses in the faecal microbiota. Host links Vincent Racaniello , Dickson Despommier , Alan Dove , and Rich Condit Links for this episode: WHO declares end of influenza H1N1 pandemic CDC's FluView WHO global monitoring of influenza Locally acquired dengue in Key West, Florida ( MMWR ) CDC page...
Aug 15, 2010•1 hr 35 min
On episode #94 of the podcast This Week in Virology , Vincent, Alan, and Rich speak with Ila Singh about the new human retrovirus XMRV, and how her laboratory is studying its association with prostate cancer and chronic fatigue syndrome. Host links Vincent Racaniello , Alan Dove , Rich Condit , and Ila Singh Links for this episode: CFIDS Association of America Discovery of XMRV ( PLoS Pathogens ) Detection of XMRV in CFS patients ( Science ) Presence of XMRV in malignant prostate ( PNAS ) Inhibi...
Aug 08, 2010•1 hr 18 min
On episode #93 of the podcast This Week in Virology , Vincent, Alan, and Rich answer listener questions about lab procedures, prokaryotes, endogenous retroviruses, the iPad and teaching, prions, mimivirus, splitting water with viruses, and the polio outbreak in Tajikistan. Host links Vincent Racaniello , Alan Dove , and Rich Condit Links for this episode: Biomedical Advanced Research and Development Authority ( BARDA ) SIGA responds to BARDA request for smallpox antiviral BARDA contract for filo...
Aug 01, 2010•1 hr 45 min
Vincent, Rich, Karla, and Marilyn recorded TWiV at the 29th Annual Meeting of the American Society for Virology in Bozeman, where they discussed plant viruses and how they make plants resistant to adverse conditions, and identification of dominant negative drug targets. Host links Vincent Racaniello , Rich Condit , Karla Kirkegaard , and Marilyn Roosinck Links for this episode: Lifestyles of plant viruses Using pyrosequencing to understand virus ecology A virus in a fungus in a plant Trans-domin...
Jul 25, 2010•58 min
On episode #91 of the podcast This Week in Virology , Vincent, Dickson, Alan, Rich and Welkin discuss the nature, origin, and evolution of endogenous retroviruses (ERVs), and the recent finding of endogenous filovirus genomes in mammals. Host links Vincent Racaniello , Dickson Despommier , Alan Dove , Rich Condit , and Welkin Johnson Links for this episode: Welkin blogs at Small Things Considered Constructing primate phylogenies from ancient retrovirus sequences ( PNAS ) Filoviruses are ancient ...
Jul 18, 2010•1 hr 29 min
On episode #90 of the podcast This Week in Virology , Vincent, Alan, Rich and Eric discuss identification of viruses in Northeastern American bats, vaccinia virus infection after sexual contact with a military vaccinee, and identification of a new flavivirus from an Old World bat in Bangladesh. Host links Vincent Racaniello , Alan Dove , Rich Condit , and Eric F. Donaldson Links for this episode: Vaccinia virus infection after sexual contact with vaccinee Smallpox vaccination overview Smallpox v...
Jul 11, 2010•1 hr 29 min
On episode #89 of the podcast This Week in Virology , Vincent and Alan review recent findings on the association of the retrovirus XMRV with ME/CFS, reassortment of 2009 pandemic H1N1 influenza virus in swine, and where influenza viruses travel in the off-season. Host links Vincent Racaniello and Alan Dove Links for this episode: Conflicting XMRV papers on hold Leak of PNAS paper CDC study on XMRV in CFS patients ( Retrovirology ) and Science update Where influenza viruses travel in the off seas...
Jul 04, 2010•1 hr 18 min
On episode #88 of the podcast This Week in Virology , Vincent, Alan, and Marc discuss using a virus for beetle control, RNA based gene therapy for AIDS, and reconstitution of a endogenous human retrovirus. Host links Vincent Racaniello , Alan Dove , and Marc Pelletier Links for this episode: Controlling the palm rhinoceros beetle with a virus The virologist in the Hawaiian shirt Information on Orcytes rhinocerus nudivirus ( one , two , three ) RNA based gene therapy for AIDS Reconstitution of an...
Jun 27, 2010•1 hr 31 min
On episode #87 of the podcast This Week in Virology , Vincent, Alan, and Rich hear from Professor Graham Hatfull how students in the Phage Hunters Integrating Research and Education (PHIRE) program learn about scientific inquiry by doing research on bacteriophages. Host links Vincent Racaniello , Rich Condit , Alan Dove , and Graham Hatfull Links for this episode: Bacteriophage Research: Gateway to learning science Mycobacterium smegmatis at NCBI Prof. Steve Cresawn Scientist infected with compu...
Jun 20, 2010•1 hr 26 min
On episode #86 of the podcast This Week in Virology , Vincent and Rich travel to the Blood Systems Research Institute in San Francisco to speak with Eric Delwart about his work on virus discovery. Host links Vincent Racaniello , Rich Condit , and Eric Delwart Links for this episode: List of Dr. Delwart's open-access journal articles ( pdf ) - to find each one, type PMID # into PubMed CDC says don't give rotavirus vaccines to infants with SCID The Brighton Collaboration Product sheet for RotaTeq ...
Jun 13, 2010•1 hr 21 min
On episode #85 of the podcast This Week in Virology , Vincent and Michael Gale discuss the origin, pathogenesis, prevention, of hepatitis C virus, and how it evades innate immune responses. Host links Vincent Racaniello and Michael Gale Links for this episode: The Gale Laboratory at the University of Washington Incredible view from the Gale laboratory ( jpg ) Evasion and disruption of innate immune signalling by hepatitis C and West Nile viruses ( review ) New potent HCV inhibitor HCV virion and...
Jun 06, 2010•56 min
On episode #84 of the podcast This Week in Virology , Vincent and Rich spoke with Dave Bloom and Grant McFadden about their work on herpesviruses and poxviruses in this episode recorded before an audience at the University of Florida, Gainesville - home of the Gators . Host links Vincent Racaniello , Rich Condit , Dave Bloom , and Grant McFadden Links for this episode: Epigenetic modulation of herpes simplex virus gene expression (thanks, Matthew!) The Red Queen and Tierra virtual environment: a...
May 31, 2010•1 hr 39 min
On episode #83 of the podcast This Week in Virology , Vincent, Alan, Rich, and special guest Dr. Kirsten Sanford talk about her career in science media, then consider whether smallpox eradication led to the AIDS pandemic, high fidelity RNA synthesis, and a new Ebola virus vaccine. Host links Vincent Racaniello , Alan Dove , Rich Condit , and Kirsten Sanford Links for this episode: Does smallpox vaccine protect against HIV? (thanks, Srinivas; Washington Post and BMC Immunology ) Was the deltaCRR5...
May 23, 2010•1 hr 31 min
On episode #82 of the podcast This Week in Virology , Vincent and Rich talk about how thymic selection of T cells might lead to better control of HIV-1 infection, and a mouse model for severe antibody-induced dengue virus disease. Host links Vincent Racaniello and Rich Condit Links for this episode: Effect of thymic selection of T-cells on control of AIDS Mouse model of antibody-induced severe dengue virus disease Natural antibody protects against viral infection Kary Mullis idea for fighting in...
May 16, 2010•1 hr 22 min
On episode #81 of the podcast This Week in Virology , Vincent and Rich answer listener questions on viruses and gluten allergy, RNA silencing, influenza virus, herpes simplex virus, HIV/AIDS, chronic fatigue syndrome, manicure salons, and the koala tea of Marseilles. Host links Vincent Racaniello and Rich Condit Links for this episode: Virus infections and gluten intolerance on TWiS (thanks Jesper!) Viral small RNAs in PLoS Pathogens (thanks Jason!) Canadian Summit Awards (thanks Jim!) Experimen...
May 09, 2010•1 hr 35 min
On episode #80 of the podcast This Week in Virology , Vincent, Alan, and Rich speak with Michael Bouchard about hepatitis B virus discovery, replication, and pathogenesis. Host links Vincent Racaniello , Alan Dove , Rich Condit , and Michael Bouchard Links for this episode: The enigmatic X gene of hepatitis B virus Tableau public (thanks Ricardo!) Molecular phylogeny of Archaea from soil (thanks Etienne!) Habitats of Archaea (thanks Cedric!) Timer remote controls (thanks Bill!) Letters read in e...
May 03, 2010•1 hr 20 min
On episode #79 of the podcast This Week in Virology , Vincent and Alan converse about making published science accessible to everyone, global eradication of poliomyelitis, and whether a plant virus can cause disease in humans. Host links Vincent Racaniello and Alan Dove Links for this episode: Making published science accessible to everyone ( Nature News ) Federal Research Public Access Act Is disease eradication a waste of money ? Do we have an ethical obligation to eradicate polio? Signs of pr...
Apr 25, 2010•1 hr 11 min
On episode #78 of the podcast This Week in Virology , Vincent, Alan, Dickson, and Rich talk about treating arthritis with a tanapox virus protein, Darwinian evolution of prions in cell culture, and the connection between cold weather fronts and outbreaks of avian H5N1 influenza in Europe. Host links Vincent Racaniello , Alan Dove , Dickson Despommier , and Rich Condit Links for this episode: Treating arthritis with a tanapox virus protein that antagonizes TNF ( press release and research article...
Apr 18, 2010•1 hr 13 min
On episode #77 of the podcast This Week in Virology , Vincent, Alan, and Rich revisit circovirus contamination of Rotarix, then discuss poxvirus-like replication of mimivirus in the cell cytoplasm, and whether seasonal influenza immunization increases the risk of infection with the 2009 H1N1 pandemic virus. Host links Vincent Racaniello , Alan Dove , and Rich Condit Links for this episode: Contamination of Rotarix vaccine with porcine circovirus 1 DNA Do you want to know what is in your vaccines...
Apr 11, 2010•1 hr 23 min
On episode #76 of the podcast This Week in Virology , Vincent speaks with Stephen Goff about the origin of the retrovirus XMRV and its association with prostate cancer and chronic fatigue syndrome. Host links Vincent Racaniello and Stephen Goff Links for this episode: Discovery of XMRV in prostate tumors Association of XMRV with chronic fatigue syndrome Enhanced infection of prostate cells by XMRV XMRV and xenotransplantation...
Apr 04, 2010•55 min
On episode #75 of the podcast This Week in Virology , Vincent, Alan, and Matt review contamination of Rotarix with circovirus DNA, antigenic similarity between 1918 and 2009 H1N1 influenza, a collection of rabies reports, and chicken pox mistaken for smallpox in Uganda. Host links Vincent Racaniello , Alan Dove , and Matthew Frieman Links for this episode: Contamination of Rotarix vaccine with porcine circovirus 1 DNA Beak and feather disease circovirus (BFDV) threatens parrots Antigenic similar...
Mar 28, 2010•1 hr 20 min
On episode #74 of the podcast This Week in Virology , Vincent speaks with Adolfo Garcia-Sastre about the origin, pathogenesis, and prevention of the 2009 pandemic influenza H1N1 virus. Host links Vincent Racaniello and Adolfo Garcia-Sastre Links for this episode: Influenza virus receptor specificity and disease PB1-F2 expression by 2009 H1N1 strain does not increase virulence Protection against 2009 H1N1 infection by immunization with older strains Passage in eggs changes influenza receptor spec...
Mar 22, 2010•47 min
On episode #73 of the podcast This Week in Virology , Vincent, Dickson, and Rich discuss multipotent progenitor bone marrow cells as a reservoir of HIV-1, integration of HHV-6 into telomeres, and dispersal of West Nile virus across the US by mosquitoes. Host links Vincent Racaniello , Dickson Despommier , and Rich Condit Links for this episode: HIV-1 infects multipotent progenitor cells HHV-6 genome integrates into telomeres A role for mosquito-mediated dispersal of West Nile virus across the US...
Mar 14, 2010•1 hr 27 min
On episode #72 of the podcast This Week in Virology , Vincent, Dickson, Alan and Rich explain CRISPR/Cas, the immune system of bacteria and archaea, how novel viruses are discovered by deep sequencing of small RNAs, and the relationship between dry weather and outbreaks of West Nile virus infection. Host links Vincent Racaniello , Dickson Despommier , Alan Dove , and Rich Condit Links for this episode: Review on the CRISPR/cas system of bacteria and archaea Virus discovery by sequencing small vi...
Mar 08, 2010•1 hr 26 min
On episode #71 of the podcast This Week in Virology , Vincent, Dickson, Alan and Rich answer listener questions about maternal infection and fetal injury, viral gene therapy, eyeglasses and influenza, filtering prions from blood, eradication of rinderpest, Tamiflu resistance of H1N1 influenza, bacteriophages and the human microbiome, H1N1 vaccine recalls, human tumor viruses, RNA interference, and junk DNA. Host links Vincent Racaniello , Dickson Despommier , Alan Dove , and Rich Condit Links fo...
Feb 28, 2010•1 hr 28 min
On episode #70 of the podcast This Week in Virology , Vincent, Dickson, and Alan consider a broad spectrum antiviral against enveloped viruses, how a plant virus induces chemical signals in the host to maximize its spread, a new way to preserve viral vaccines at tropical temperatures, and the continuing story of XMRV and chronic fatigue syndrome. Host links Vincent Racaniello , Dickson Despommier , and Alan Dove Links for this episode: Broad spectrum antiviral against enveloped viruses Chemical ...
Feb 21, 2010•1 hr 17 min
