Stanley Plotkin joins TWiV to recount his career as a vaccinologist, having participated in the development of vaccines for polio, rabies, and rubella, and his thoughts on the current anti-science, anti-public health, and anti-vaccine climate. Hosts: Vincent Racaniello , Rich Condit , and Kathy Spindler Guest: Stanley A. Plotkin Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Stanley Plotkin (History of Vaccine...
Aug 24, 2025•1 hr 48 min•Ep. 1247
In his weekly clinical update, Dr. Griffin with Vincent Racaniello discusses outbreaks of Vibrio vulnificus and Legionnaire’s disease in Harlem, the role of the American Association of Pediatrics defining immunization practices, before Dr. Griffin deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, effective of the high and low does influenza vaccines, association Gullian-Barre syndrome with RSV vaccination, guidelines for using RSV vacc...
Aug 23, 2025•54 min•Ep. 1246
TWiV reviews fradulent science becoming an industry, FDA may not authorize Pfizer COVID vaccine for young kids, Kennedy won’t push strict pesticide regulations conserved betacoronavirus sequences recognized by human T cells, and Bispecific antibodies protect against herpes recurrent disease. Hosts: Vincent Racaniello , Alan Dove , and Brianne Barker Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Frontiers in C...
Aug 17, 2025•1 hr 49 min•Ep. 1245
In his weekly clinical update, Dr. Griffin with Vincent Racaniello discusses Vijay Prasad’s return to the FDA, revoking of COVID vaccine authorization for young children, the Legionnaires’ outbreak in Harlem, the new labeling requirements for Ixchiq, the infectious attenuated Chikungunya vaccine and the importation of H5 influenza virus in Antarctica, before Dr. Griffin deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, guidelines for t...
Aug 16, 2025•43 min•Ep. 1244
TWiV discusses the latest worrisome Executive Order on oversight of federal grantmaking, RFK Jr winds down mRNA viral vaccine development, Lenacapavir, a drug for AIDS prevention and treatment, and how respiratory virus infections awaken dormant metastatic breast cancer cells in lungs. Hosts: Vincent Racaniello , Alan Dove , Rich Condit and Brianne Barker Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Oversigh...
Aug 10, 2025•1 hr 53 min•Ep. 1243
In his weekly clinical update, Dr. Griffin with Vincent Racaniello re-address the dangers of drinking raw milk, the Legionnaire’s outbreak in Harlem and results of a vaccine knowledge survey done by emergency departments before Dr. Griffin deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, reports of influenza-associated acute necrotizing encephalopathy or neuropsychiatric events in children, whether or not the NB.1.8.1 should be includ...
Aug 09, 2025•47 min•Ep. 1242
TWiV reports the administration putting a choke hold on billions of NIH health research funding, US Senators tell scientists they want to protect the NIH budget, then review a classic experiment showing the mechanism of DNA replication, and explain how jumbo phage DNA is transcribed in a membrane-bound compartment before transfer into proteinaceous “nucleus” compartment. Hosts: Vincent Racaniello , Rich Condit , Kathy Spindler , Brianne Barker , Jolene Ramsey , and Angela Mingarelli Subscribe (f...
Aug 03, 2025•1 hr 57 min•Ep. 1241
In his weekly clinical update, Dr. Griffin with Vincent Racaniello chat about the recent Salmonella typhimurim outbreak, the ousting of another CBER director, confirmation of a new CDC director and results of a recent pool about vaccine safety and trust before Dr. Griffin deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, a new anti-influenza antibody that can be combined with neuraminidase inhibitors, whether or not the NB.1.8.1 should...
Aug 02, 2025•48 min•Ep. 1240
TWiV explains a cohort study of over one million Danish children which shows no evidence supporting an increased risk for autoimmune, atopic or allergic, or neurodevelopmental disorders associated with early childhood exposure to vaccines with aluminum-base adjuvants, and a study of antibodies induced by mRNA-1273 and NVX-CoV2373 COVID-19 vaccines which show that polyclonal antibodies against a single site on the spike N-terminal domain show immunodominance, high diversity, and limited cross-rea...
Jul 27, 2025•1 hr 51 min•Ep. 1239
In his weekly clinical update, Dr. Griffin with Vincent Racaniello chat about how flies and milk-snatching might contribute to influenza virus H5N1 among dairy cattle, the recent pertussis oubreak and measles epidemic before Dr. Griffin discusses monoclonal antibody therapy can enrich for RSV variants before deep diving into recent statistics on RSV, influenza and SARS-CoV-2 infections the Wasterwater Scan dashboard, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, the e...
Jul 26, 2025•45 min•Ep. 1238
From the 2025 annual meeting of the American Society for Virology, Charlie Rice, 2020 Nobel Laureate in Physiology or Medicine, talks with Vincent and Kathy about his career and the scientific difficulties he and his laboratory encountered in their attempts to achieve replication of hepatitis C virus in cells in culture. Hosts: Vincent Racaniello and Kathy Spindler Guest: Charlie Rice Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science e...
Jul 20, 2025•1 hr 6 min•Ep. 1237
In his weekly clinical update, Dr. Griffin with Vincent Racaniello have a morning chat about the measles epidemic and H5N1 in cows before Dr. Griffin discusses how vaccination associates with reduced dementia risk before deep diving into recent statistics on measles epidemic, RSV, influenza and SARS-CoV-2 infections the Wasterwater Scan dashboard, a potential new influenza antiviral drug, whether or not the NB.1.8.1 variant should be included in the fall 2025 vaccines, immunization recommendatio...
Jul 19, 2025•49 min•Ep. 1236
David Barton, Brian Kemp, and Olve Peersen join TWiV to discuss RNA recombination among enteroviruses and its role in foiling poliovirus eradication. Hosts: Vincent Racaniello , Alan Dove , and Rich Condit Guests: David Barton , Brian Kempf , and Olve Peersen Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Enterovirus C recombination groups (J Virol) Poliovirus polymerase L420 facilitates RNA recombination (J V...
Jul 13, 2025•1 hr 36 min•Ep. 1235
In his weekly clinical update, Dr. Griffin with Vincent Racaniello note that history is being rewritten for justification of changes in COVID vaccine guidelines including myocarditis incidence and the Great Barrington Declaration ignoring presentations at the April 2025 ACIP, the response by the medical community to these changed guidelines, before Dr. Griffin discusses how vaccination associates with reduced dementia risk before deep diving into recent statistics on measles epidemic, RSV, influ...
Jul 12, 2025•55 min•Ep. 1234
TWiV covers FDA Director overriding scientists on COVID shots, NIH funded science must now be free to read instantly, Trump cuts subscriptions to Springer Nature journals, UK and Gates make up for US money withdrawn from GAVI, US defunding USAID could lead to 14 million deaths by 2030, then reviews research on how host IL1 genetics regulates Epstein-Barr virus reactivation and long COVID, and enhanced antiviral capacity of bat innate immunity. Hosts: Vincent Racaniello , Alan Dove , and Rich Con...
Jul 06, 2025•1 hr 51 min•Ep. 1233