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This Week in Startups

Jason Calacanisthisweekinstartups.com
Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.
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Episodes

The $60 billion resource hiding in space, and the start trying to mine it (feat. Matt Gialich, Astroforge) | E2268

This Week In Startups is made possible by: Wispr Flow - https:// wisprflow.ai/twist Circle - http://circle.so/twist Deel - http:// deel.com/twist Today’s show: AstroForge is building low-cost, replicable spacecraft to mine platinum group metals from near-Earth asteroids — a $60 billion annual market for materials that are running out on Earth. Founder and CEO Matt Gialich joins the show to talk about the company's ambitious mission, what went wrong on their first two flights, and why Mission 3 c...

Mar 27, 20261 hr 39 minEp. 2268

This Bittensor Subnet Could Cut Drug Discovery Costs in HALF | E2267

This Week In Startups is made possible by: Luma AI - https://lumalabs.ai/twist Every.io - https:// every.io Lemon.io - https:// Lemon.io/twist Plaud - https:// Plaud.ai/twist Today’s show: What do drug discovery, the creator economy, and AI vision models have in common? In the case of Metanova, Bitcast, and Score, the answer is Bittensor. Yes, each of the three companies leverages the Bittensor network to get more work done, more quickly, in a completely decentralized fashion. Metanova uses its ...

Mar 26, 20261 hr 13 minEp. 2267

$2.5B Chip Heist, The Future of American AI, and Purpose-Built Robots | This Week in AI Ep 6

This Week in AI sneak peak! If you enjoy the episode find us on Spotify, Apple podcasts and YouTube by looking up "This Week in AI" or by going to thisweekinai.ai This week Jason sat down with Jake Loosararian and Chris Lattner on Episode 6 of This Week in AI. Jake is the CEO and co-founder of Gecko Robotics, a company deploying purpose-built robots and AI for mission-critical infrastructure inspection across energy, defense, and manufacturing. Chris is the CEO and co-founder of Modular, buildin...

Mar 25, 20261 hr 15 minEp. 6

Compliance Startup Scandal... Is Delve Guilty? | E2266

This Week In Startups is made possible by: Northwest Registered Agent - https://northwestregisteredagent.com/twist LinkedIn Jobs - https://linkedIn.com/twist Sentry - https://sentry.io/twist Plaud - http://Plaud.ai/twist Ro.co - http://Ro.co/Twist Today’s show: Hustle Fund general partner Elizabeth Yin joined Jason and Alex to discuss how rapid advances in AI have changed the venture capital game, and how the same AI updates are changing how founders build. Founders may need less capital than be...

Mar 24, 20261 hr 27 minEp. 2266

The Drone Company Everyone Thought Was Illegal (Now Worth $4B+) | E2265

This Week In Startups is made possible by: Northwest Registered Agent - https:// www.northwestregisteredagent.com/twist Circle - https://circle.so/twist Netsuite - https://www.netsuite.com/twist Today’s show: Zipline founder Keller Cliffton started his company with a simple premise: build automated logistics that serve everyone equally. The only problem? It was literally illegal in the US. In this live recording from LaunchFest in San Francisco, Keller shares how Zipline went from a 20-person te...

Mar 20, 20261 hr 39 minEp. 2265

How Robinhood became a $68B company w/ Vlad Tenev

This Week In Startups is made possible by: Deel - https:// deel.com/twist LinkedIn Jobs - https:// LinkedIn.com/twist . Iru - https:// iru.com/twist Today’s show: We’ve got a treat for you today on TWiST! Jason is live from LAUNCH Fest in San Francisco, where he’s joined by Robinhood founder Vlad Tenev. The era of AI is here. Robinhood found success in the midst of the last great technological shift. What lessons did Vlad take from this, and how can founders apply these to this next transformati...

Mar 18, 202650 minEp. 2264

Are Brain-Computer Interfaces Actually Ready for Humans?

This Week In Startups is made possible by: Caldera + Lab - https://CalderaLab.com/TWIST Northwest Registered Agent - https://northwestregisteredagent.com/twist Lemon - https://Lemon.io/twist Today’s show: Computers that read your mind? Jets that are all wings? Continuously tracking your body’s vital signs to live longer? We’ve got all that and more on the show today. First, we sat down with the CEO of Paradromics, Matt Angle, to dig into the progress that his brain-computer interface startup has...

Mar 16, 20261 hr 14 minEp. 2263

One Genius Rule That Made This Coffee Brand Famous | EP 2262

Legendary British ad man Rory Sutherland invented a fake business on a podcast, a coffee shop appealing to the busy commuter called “Flat White or F**k Off.” But it’s one thing to have a post go big on TikTok or Instagram… but to turn that viral moment into an actual COMPANY is a very different challenge. On TWiST, Jason and Lon chat with Charlie Hurst, Tom Noble, and Will Sudlow, founders of the online brand “Flat White or F**k Off,” about how they took a funny little slogan and turned it into ...

Mar 14, 20261 hr 30 minEp. 2262

The Global Expansion of Self-Driving Vehicles

This Week In Startups is made possible by: Circle - http://circle.so/twist Sentry - http:// Sentry.io Deel - http://deel.com/twist Plaud - http://Plaud.ai/twist Today’s show: It’s self-driving time! We’re going deep on one of the most exciting spaces developing in the world, autonomous vehicles! We’ve got 3 experts on the show to talk to us enlighten us, Ben Seidl of Autolane, Ming Maa of Moove, and Nathan Parker of EdgeCase. What’s going on in the world of self-driving? How has the reliability ...

Mar 11, 20261 hr 9 minEp. 2261

How agents will change banking forever | E2260

This Week In Startups is made possible by: Northwest Registered Agent - ⁠⁠northwestregisteredagent.com/twist⁠⁠ Quo - ⁠⁠quo.com/TWiST⁠⁠ Gusto - ⁠⁠Gusto.com/twist⁠⁠ Plaud - http://Plaud.ai/twist Athena - https://www.athena.com/jcal Today’s show: How long until AI models can improve AI models? Once possible, recursive self-improvement by AI technology could accelerate — forever. Thus far, humans (and their coding agents) are still driving AI progress. But a recent project by AI developer extraordin...

Mar 10, 20261 hr 1 minEp. 2260

Wisdom of the $TAO: the future is decentralized AI

This Week In Startups is made possible by: Every Banking - https:// Every.io https:// Lemon.io - Lemon.io/twist Wispr Flow - https:// wisprflow.ai/twist Plaud - https:// plaud.ai/twist Ro.co - https:// Ro.co/Twist Today’s show: *Sure, we all love open source models, but what about completely decentralized AI? Rather than leaving the big decision-making in the hands of a few elite CEOs, shouldn’t users have a say — and potentially even a stake — in how this incredible technology develops? On TWiS...

Mar 06, 20261 hr 8 minEp. 2259

Is Anthropic Making the Biggest Mistake in AI History | E2258

This Week In Startups is made possible by: Plaud - Plaud.ai/twist LinkedIn Jobs - https:// LinkedIn.com/twist . Deel - https:// deel.com/twist Iru - https:// iru.com /twist! Today’s show: It’s a packed TWiST Today! WITH US, we’ve got Erik Voorhees of VeniceAI and Logan Allin of Fin Capital on to talk agents, crypto, and… you guessed it, OPENCLAW! Where does agentic AI meet the financial system? How will agents transact? And what does privacy look like in a world with omnipresent AI? Stick around...

Mar 05, 20261 hr 21 minEp. 2258

How the OpenClaw foundation bullet-proofed its future (w/Dave Morin) | E2257

This Week In Startups is made possible by:Circle — http://circle.so/twistHubspot Creators — http://clickhubspot.com/twist2Uber AI Solutions — http://uber.com/ai-solutionsToday’s show: *Dave Morin joined the show today to explain how the OpenClaw Foundation came into existence, and what its goals are. Fear not, Peter Steinberger retains directional control of the project. But if you want to sustain an open-source project over time, you need a corporate entity, well-heeled sponsors, maintainers an...

Mar 03, 20261 hr 15 minEp. 2257

The Biggest Private Funding Round in History | E2256

This Week In Startups is made possible by: Deel - http://deel.com/twist Wispr Flow - https://wisprflow.ai/twist Luma AI - https://lumalabs.ai/twist Today’s show: *$110 billion buys you 15% of OpenAI. Amazon, Nvidia, and SoftBank placed their bets on ChatGPT, which now has 900 million weekly active users and 50 million paying subscribers. Find out why Jason is anticipating the wildest J-Curve swing of all time, and believes we’ve ALREADY hit AGI… it’s just not implemented yet. Plus a visit from o...

Feb 28, 20261 hr 20 minEp. 2256

Behind the Scenes with an early OpenClaw contributor! | E2252

This Week In Startups is made possible by: Lemon IO - https://Lemon.io/twist Every.io - https://every.io Sentry.io- https://sentry.io/twist Today’s show: We’re going behind the curtain today — it’s a packed show! We found Tyler Yust, OpenClaw’s third EVER contributor to share his insights from within foundation! We’ve got Deedy Das, of Menlo Ventures, on the show to discuss whether SaaS is cooked! Next we met the creator of an OpenClaw instance that fits in your pocket! We’ve also got the founde...

Feb 26, 20261 hr 22 minEp. 2255

Kill Your Startup’s Knowledge Chaos with OpenClaw (with Oliver Henry and Jeff Weisbein) | E2254

This Week In Startups is made possible by:Caldera Lab - [calderalab.com/twist](https://calderalab.com/twist)Iru - [iru.com](http://Iru.com/twist)LinkedIn Jobs - http://linkedin.com/twist*OpenClaw is incredible at automating tasks. But what if it could also fix your startup’s internal communication problems? Give agents shared memory, and you may be able to break down information silos while ensuring that teammates have the same context.@oliverhenry and @jeffweisbein demo what they’ve actually bu...

Feb 24, 20261 hr 19 minEp. 2254

We Asked 3 Experts How to Get More Value out of OpenClaw | E2253

This Week In Startups is made possible by: Gusto - https://Gusto.com/twist Circle - https://circle.so/twist Northwest Registered Agent - https://northwestregisteredagent.com/twist Today’s show: *Getting OpenClaw set up and running without destroying your bank account is one thing. But now that you have your agent or swarm operational, how can you use them to get real work done? We have three builders who are going to show you how to maximize your OpenClaw output! GUESTS: Jordy Coltman: Viral X a...

Feb 21, 20261 hr 9 minEp. 2253

When Will Openclaw go Mainstream? | E2252

This Week In Startups is made possible by: Gusto - Try Gusto today and get 3 months free at gust.com/twist Crusoe Cloud - Reserve your capacity for the latest GPU’s at crusoe.ai/savings Uber AI Solutions - Book a demo today at http://uber.com/ai-solutions Today’s show: It’s a packed show! We’ve got YouTuber and Openclaw enthusiast Matthew Berman, Ryan Yaneli, founder of Nextvisit, and Jason Grad, founder of Massive! We’re all in on Openclaw, but we have no doubts there’s still room in the market...

Feb 19, 20261 hr 2 minEp. 2252

Will OpenAI Tank OpenClaw? | E2251

Will OpenAI Tank OpenClaw? | E2251 This Week In Startups is made possible by: Northwest Registered Agent - https://www.northwestregisteredagent.com/twist Lemon IO - https://lemon.io/twist LinkedIn Jobs - http://linkedin.com/HiringProOffer Today’s show: *OpenAI hired OpenClaw creater Peter Steinberger. What does this mean for the future of the AI virtual assistant platform, and what can the OpenClaw community do TODAY to help protect their favorite free, open-source resource? Jason and Alex consi...

Feb 17, 20261 hr 27 minEp. 2251

OpenClaw is Our Friend Now | E2250

This Week In Startups is made possible by: Sentry - http://sentry.io/twist Circle - http://Circle.so/twist Wispr Flow - https://wisprflow.ai/twist Today’s show: What makes OpenClaw feel so much more ALIVE than other AI agents? On TWiST, we’re welcoming three amazing builders who are truly connecting with their OpenClaw bots, not just using them for productivity but getting to know them and their personalities on a deeper level. Serial entrepreneur Ryan Carson shows us Antfarm, which creates a te...

Feb 14, 20261 hr 6 minEp. 2250

Why J-Cal Invested to 200K in a former Employee | E2249

This Week In Startups is made possible by: NetSuite - https://www.netsuite.com/twist Luma AI - https://lumalabs.ai/twist Squarespace - https://squarespace.com/twist Today’s show: On today’s epsiode of TWiST, Jason gets pitched by two top founders, Presh Dineshkumar and Peter Cetale! Presh used to work for Jason at Launch! When he left, Jason invested $200K into Presh’s new startup The Wellness Company. Presh pitches Jason on what he has been building, and Jason gives Presh advice for improving t...

Feb 12, 202640 minEp. 2249

How These 3 Founders are building on Open Claw | E2248

This Week In Startups is made possible by: Hubspot - http://clickhubspot.com/twist2 Deel - http://deel.com/twist Iru - http://www.iru.com/ Today’s show: Today on TWiST we’re joined by 3 founders building on Open Claw, Presh Dineshkumar, Vishnu, and Sean Liu! First, long time friend of the pod, Presh Dineshkumar, shows us how he’s using Open Claw to automate his work at The Wellness Company. His Open Claw agent, Eywa, lives in his email and in his product, able to compile user lists at his discre...

Feb 12, 202645 minEp. 2248

Does Clawdbot (OpenClaw) Need Eyes? (feat. Alex Finn and Matt Van Horn) | E2247

This Week In Startups is made possible by: LinkedIn - http://linkedin.com/twist Every.io - http://every.io/ Northwest registered Agent - www.northwestregisteredagent.com/twist Today’s show: Sean Liu gave his OpenClaw “eyes” by hooking the AI assistant up to his Meta Ray Bans. While Jason and Alex consider the implications… guest expert Alex Finn quickly loses interest… It’s another All-Clawdbot TWiST where we debate the most essential uses for the viral agent platform. For their part, Alex Finn ...

Feb 10, 20261 hr 8 minEp. 2247

We built OpenClaw Ultron to replace 20 people at our company | E2246

This Week In Startups is made possible by: Crusoe Cloud - https://crusoe.ai/savings Lemon IO - https://Lemon.io/twist Northwest Registered Agent - https://www.northwestregisteredagent.com/twist Thanks to our guests: Alex Cheema of ExoLabs http://exolabs.net Ryan Yanneli of NextVisit https://nextvisit.ai/ Today’s show: It’s the Age of Ultron at TWiST and LAUNCH. We’ve given our OpenClaw digital Replicants the keys to all of our systems and we’re seeing how much of our jobs they can really do when...

Feb 07, 20261 hr 11 minEp. 2246

Savvy is HQ Trivia + Wordle (feat. Scott Rogowsky) | E2245

This Week In Startups is made possible by: Circle - http://Circle.so/twist Caldera Lab - http://calderalab.com/TWIST LinkedIn - http://linkedin.com/twist Today’s show: There was a time, not long ago, when offices everywhere came to a standstill, and everyone became even more fixated on their phones than usual, each time HQ Trivia went live. The app-based game show was a massive viral hit… until suddenly, around a year later, it wasn’t. Now, HQ Trivia host Scott Rogowsky is back with a new concep...

Feb 04, 202654 minEp. 2245

Where early-stage founders MUST focus to success | E2244

This Week In Startups is made possible by: Quadratic - http://quadratic.ai/twist Today’s show: Don’t get distracted! Here are the MOST CRUCIAL aspects of running a startup, where founders need to keep their full and uninterrupted focus. - Make sure you’re saving up your cash - Why you need to just get started and build SOMETHING - Trust and reliability is EVERYTHING for new products - Why distribution should be your top priority Download all this practical and tactical startup advice from season...

Feb 03, 20261 hr 7 minEp. 2244

SpaceX + xAI deal gets us one step closer to Musk Industries | E2243

This Week In Startups is made possible by: Uber - http://uber.com/twist Deel - http://deel.com/twist Northwest Registered Agent - https://www.northwestregisteredagent.com/twist Today’s show: SpaceX is buying xAI, forming a mega-corp that plans to launch data centers into SPACE. Will Tesla also join up, fulfilling Elon’s destiny to become real-life Tony Stark, with his own Musk Industries? Jason and Alex break down the future of SpaceXAI in a breaking news report. THEN, we’re still celebrating Op...

Feb 03, 20261 hr 2 minEp. 2243

How OpenClaw (Clawdbot) Is Rewriting the Way Our Team Works with Rahul Sood | E2242

This Week In Startups is made possible by: Deel - http://deel.com/twist LinkedIn Jobs - http://linkedin.com/twist Northwest Registered Agent - https://www.northwestregisteredagent.com/twist Today’s show: On Today’s action packed episode of This Week in Startups, our team is going full AI! Jason is joined by Oliver Korzen and Lukas Durand from the LAUNCH team, alongside Rahul Sood, founder/CEO of Irrevernt Labs and founder of Voodoo PC. With the rise of Clawdbot/Moltbot, the question on everyone’...

Jan 31, 20261 hr 28 minEp. 2242

How decriminalization led to an explosion in cannabis startups (Feat. Ford Smith, Andrew Duffy, and Socrates Rosenfeld) | E2241

This Week In Startups is made possible by: Gusto - http://Gusto.com/twist Zite - http://zite.com/twist Circle.so - http://circle.so/twist Guest links: Andrew Duffy, Founder and CEO, http://sparkplug.app — Retail incentives and brand partnerships platform Ford Smith, Founder of http://Ultranative.com — Investing in transformative startups Socrates Rosenfeld, Founder and CEO of http://iheartjane.com — One stop shop for cannabis products Today’s show: On TWiST’s first Cannabis Roundtable, Jason is ...

Jan 29, 202656 minEp. 2241

Clawdbot is an inflection point in AI history | E2240

This Week In Startups is made possible by: Quo - http://quo.com/TWiST Lemon IO - https://lemon.io/twist Northwest Registered Agent - https://www.northwestregisteredagent.com/twist Today’s show: Jason is back from Davos and Tokyo! We are jumping right back in with a group of Clawdbot power users: Alex Finn, Matt Von Horn, and Dan Penguine. Clawdbot is a hot open source AI project that lets users automate… everything! Dan helped his automate his aging parent’s tea shop, Matt built news sourcing bo...

Jan 27, 20261 hr 2 minEp. 2240
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