TWiP 222: Balamuthia in the brain with Natasha Spottiswoode
Episode description
At the meeting of the American Society for Tropical Medicine and Hygeine in Chicago, Natasha joins TWiP to solve the case of the Man with a Generalized Seizure and Infectious Forms in the Brain.
Hosts: Vincent Racaniello, Dickson Despommier, Daniel Griffin, and Christina Naula
Guest: Natasha Spottiswoode
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Links for this episode- Treatment of Balamuthia encephalitis with nitroxoline (Emerg Inf Dis)
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Case Study for TWiP 222
Haitian creole speaking, cachetic female in her 50s w/ hx HIV (noncompliant on medication), migrating from Haiti brought in by her daughter for dysphagia, cough x days, associated with NBNB vomiting, oral thrush extending to soft palate, concerning for oropharyngeal candidiasis. Weeks of nonresolving diarrhea. Admitted for failure to thrive and deconditioning, found to be Parainfluenza 3 positive), undergoing TB rule out. Diarrhea is voluminous, pt is dehydrated, there has been significant weight loss and lethargy over the last few weeks.
MHx:
HIV
Shx:
Lives in haiti
Remarried, Last sexual encounter 2 years ago.
Denies illicit drug use. Drinks alcohol
Allergies: No Active Allergies
Labs return with CD4 count in the 50s, elevated viral load. CD4 55/3%
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Music by Ronald Jenkees