TWiM #123: A microbial MAGE

Hosts: Vincent Racaniello, Michael Schmidt, and Elio Schaechter.

Guest: Harris Wang

Harris joins Vincent, Elio, and Michael to describe multiplex automated genome engineering, a method for targeting many modifications in a population of bacterial cells.

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• MAGE - Multiplex automated genome engineering (Nature)
• Genome-scale promoter engineering (Nat Methods)
• Manipulating microbial communities in situ (Trends Genet)
• Engineering human microbiomes (Meth Mol Biol)
• Genome-scale engineering (Mol Syst Biol)
• Economic framework of microbial trade (PLoS One)
• Tardigrade t-shirt
• Image credit

This episode is sponsored by Microbe Magazine Podcast and ASM Microbe 2016

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv.