Sep 06 2024 This Week in Cardiology
Episode description
Feedback on ABYSS and beta-blockers, more ESC recap, including SHAM-PVI, FINEARTS-HF, and RESHAPE HF2 trials are the topics John Mandrola, MD, discusses in today’s podcast.
This podcast is intended for healthcare professionals only.
To read a partial transcript or to comment, visit:
I. Feedback on ABYSS
Setbacks After Stopping Beta-Blockers
https://www.medscape.com/viewarticle/setbacks-after-stopping-beta-blockers-2024a1000fv7
Beta-Blockers Post-MI? No for Me, Even After the ABYSS Trial
https://www.medscape.com/viewarticle/beta-blockers-post-mi-no-me-even-after-abyss-trial-2024a1000fva
- ABYSS trial https://www.nejm.org/doi/full/10.1056/NEJMoa2404204
- REDUCE AMI https://www.nejm.org/doi/full/10.1056/NEJMoa2401479
- QOL paper REDUCE AMI https://doi.org/10.1093/ehjcvp/pvae062
- Atenolol ED paper 10.1016/j.ehj.2003.08.016
II. SHAM-PVI
- JAMA SHAM-PVI paper https://jamanetwork.com/journals/jama/article-abstract/2823283
- Gupta QOL paper https://pubmed.ncbi.nlm.nih.gov/33952593/
III. FINEARTS HF
Finerenone Benefits Heart Failure With Preserved EF
https://www.medscape.com/viewarticle/finerenone-benefits-heart-failure-preserved-ef-2024a1000fza
Topline Finerenone Results Point to Advance in Heart Failure
- FINEHEARTS -HF NEJM https://www.nejm.org/doi/full/10.1056/NEJMoa2407107
- FIDELIO-DKD https://www.nejm.org/doi/full/10.1056/NEJMoa2025845
- FIGARO-DKD https://www.nejm.org/doi/full/10.1056/NEJMoa2110956
- Why Have We Not Been Able to Demonstrate Reduced Mortality in Patients With HFmrEF/HFpEF? https://doi.org/10.1016/j.jacc.2024.08.033
IV. RESHAPE HF
TEER in Functional MR: Data Deluge, but No Easy Answers
https://www.medscape.com/viewarticle/teer-functional-mr-data-deluge-no-easy-answers-2024a1000fvg
- Mitra FR https://www.nejm.org/doi/full/10.1056/NEJMoa1805374
- COAPT https://www.nejm.org/doi/full/10.1056/NEJMoa1806640
- RESHAPE- HF2 https://www.nejm.org/doi/full/10.1056/NEJMoa2314328
- RESHAPE Subgroup paper https://doi.org/10.1016/j.jacc.2024.08.027
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