57. Unlocking Glutathione Your Body’s Super Antioxidant with Dr. Patel

So if you can age, let's see every six months, you only age one month. One that'd be better. That'd be great. You got everybody's attention right now. What was astounding to me when I started my wellness practice was the posity of knowledge and understanding about this miracle antioxidant. I understand it to be the most prevalent antioxidant of the body. Every single cell in our bodies contains blood and I am. It's manufactured by our liver. But I feel like it's the mother of all antioxidants that most people have never heard of. The reason we don't talk about glutein, even though we have more

glutein for glutein for over a hundred plus years is we have never figured out how to... Hey guys, welcome back to The Ultimate Human Podcast. I'm your host, human biologist, Gary Brecka, where we go down the road everything anti-aging, longevity, biohacking and everything in between. And today's guest, as you just heard, is a powerhouse. I actually met him at

an A4M conference. This is the big age medicine conference that's hosted once or twice a year all over the world. And I was actually absolutely enthralled by some of the products that he was developing as a pharmacist. Not only is background as a professor, but also his thorough understanding of transdermal delivery in certain, not just pharmaceuticals, but certain things like that.

Like glutathione and other things that we're trying to get into our bodies that we're trying to avoid first pass metabolism, which is our digestive system because our digestive system is a very inhospitable place. And it's a very difficult route for delivery into the body. And let's just face it, a lot of people don't like to do IVs and they don't like needle sticks. And so they're looking for other mechanisms to deliver not just pharmaceuticals, but hormones and antioxidants.

vitamins, minerals and nutrients of all kinds. So this is going to be an amazing podcast today. And I really want to welcome Dr. Patel to the podcast. It's great to have you on. It's my pleasure to be into the Gary. And truth be told, right before we started Dr. Patel told me that his wife is a fan of mine. And she follows all my videos. Right. And what forwards them to your friends. For sure to my kids and my friends, everybody.

So your kids, your friends. So great. We already know that your wife's a good person. So we don't we don't need to cover that. But you know, I, I, I want to just get right into it because I'm fascinated by your research into glutathione. And I'll tell you what my understanding is of glutathione. It's probably certainly not as in depth as yours. And I think most of my audience has heard of it. But what was astounding to me when I started my wellness practice.

Was the, um, the posity of knowledge and understanding about this miracle antioxidant. Um, I understand it to be the most prevalent antioxidant in human body. Um, every single cell in our bodies contains glutathione. It's manufactured by our liver. Um, but in times of stress. Um, or when the liver is under stress, especially you see glutathione levels drop. And therefore you have all this whole myriad of consequences.

But I feel like it's the mother of all antioxidants that most people have never heard of. Like if, if I think if you took up, let's say a slice out of middle class American, you said, you said, what's the number one antioxidant in human body? They would say things like vitamin C or, you know, blueberries have antioxidants. Um, and so I, I would love for you to take us down the road of, you know, what glutathione is, what's its role in the human body?

Why is it so important? And then we're, I would want to transition into the different delivery mechanisms and how people can benefit by adding glutathione to their regimen. Absolutely. And we just said right. People don't understand antioxidant because they used to drink orange juice, but it's all, all the antioxidants in there. Right. And so the blueberries or blueberries, whatever. Right.

So they are, they're trying to get the antioxidants from the food stores, which is, which is the right thing to do because we want them to eat the right types of fruits and vegetables every single day. But the reason we don't talk about glutathione, even though we have known for glutathione for over 100 plus years, is we have never figured out how to get inside your body.

So even though we inject it, take a pill or inhale, like I have a lot of athletes, they'll inhale a glutathione or they'll be doing a suppository or whatever, you know, whatever, whatever, whatever they, they're vaporizing. They're vaporizing. Yeah. And so the thing that they're getting into the system, but it's not there. So, so we're talking about the glutathione system next, but let's talk about what is it? Right.

So the glutathione, and you said right now, most of the people have not heard about it because of the fact that people do not understand what it is and how to deliver that part. But you're talking about middle America, but even people that have very affluent, we were recently at one of the award shows and literally 90% of the people, these are high part CEOs have never heard of glutathione before.

And I was shocked to see that's a wait a second, you have all the resources in the world, yet you have no idea what glutathione is. So, so we are talking about glutathione. First thing, it's, it's a simplest peptide of body produce. It's what I say peptide, it's a three amino acid. It's a tripeptide. It's not a protein. I could be a protein, but not really. It's a tripeptide, very simple form.

And when you combine those three amino acids together, it has, it has more than one properties. And that's what we want to find out. One of the properties, because if you, if something does does one thing that's, it's good. It's a mother of all antioxidants, that's just one of the function. Right. Because as a glutathione, what it does, it, it quenches all the free radicals because of a body is exposed to the free radicals all the time.

That's one. On top of that, a body produces free radicals because of chemical reaction happens every single in a, in a, in a life chemical waste. Yeah, chemical waste. So the free radicals are inevitable. It's always going to be nobody. And that's how you always going to be aging. Only thing that you can control is the pace. It's not if it's the pace. Right. So if you can age, let's see,

every six months, you only age one month. Right. When that be better. That would be great. And you got everybody's attention right now, including mine. So that's what we want. That's exactly what we want. And so the pace of aging has to be done. And the free radicals are always going to produce. So that's one of the function. That's why that's what is known for the most.

The second part that nobody talks about this thing is glute thion actually helps with phase one phase two detoxification pathways for making sure active saliva. And and basically helps carry off all the chemicals we exposed to. You know, I don't want to cut you off with that. But before we get further, I want to talk about phase one and phase two detoxification because I'm, I'm a huge fan of methylation. And I decided to dedicate the balance of my adult lifetime to the study of methylation.

And these methylation pathways dump into two main pathways. One is transulfuration. The other one is glutathione synthesis. And we absolutely see impaired methylation leading to poor glutathione synthesis, having demonstrative consequences in the onset of the severity of and eventually how quickly people succumb to disease.

And pathology, I assume that it must have something to do with the inflammatory process or what have you. So can you talk a little bit about phase one and phase two detoxification when you use those terms, what are you referring to for the audience? I'm looking for those liver enzymes. I'm making sure the CYP enzymes, which one hasn't been as not clearing up effectively.

Okay. Because if you're exposing yourself to let's see hormones and if you have CYP 1B1 enzyme gene mutation, then it doesn't matter. All the hormones you're taking is actually working against you because your body cannot clear them out. Right. So that's what I'm talking about. So there's a lot of medications that you take, a lot of foods you eat that the liver has to clean out.

And if you have one of those gene SNPs that your body cannot metabolize it or conjugate it, you have an issue with buildup of all this all this medication in your body that is actually working against you. The second body talk about the CYP, the methylation transferase as well as the glutathione transferase. The glutathione transferase is a protective system that is activated because the need for glutathione has increased so much that so the body activates those systems to produce glutathione.

Now it needs three things, right? Three amino acids, two enzymes and a catalyst like selenium to produce one molecule of glutathione. And with that, there's two things that requires ATP and NAD. So I mean, it's a multifactoral problem and I don't know how much stuff we can replace.

Can we replace ATP? Maybe not. Can we replace NAD? Maybe. Can we replace the amino acids? Maybe. Can we replace the two enzymes? You know, that's sketchy. Can we replace selenium? It's a heavy metal. How much do we replace? So it's a very delicate balance and sometimes us humans want to take over our body's natural process. You know what? Don't worry. I'll just give it to you, GlowThon as this.

So don't worry about it, right? We got you covered. So don't work too hard. We got you covered. And so we want to make sure that the body doesn't have the capacity to response to respond to bodies. Needs are. Then you have to find an alternative source to deliver this GlowThon into the system. Now what about people that because I've read Tan Gently.

I don't know that I've actually read a clinical study about this, but that if you take too much glutathione, you'll reduce your endogenous production, delivers production of GlowThon or that you should cycle on and off of GlowThon supplements. This was in an article that was about intravenous GlowThon, high dose intravenous GlowThon. And that by administering it too often too frequently or in too high of a dosage that you would actually reduce your endogenous production is.

So I think that again, there's no studies have been done like that. So we do not know if that's for sure or not. But I truly believe that if you give exogenous GlowThon, especially the way the body can absorb it correctly, that it will shut down your own production. But keep in mind GlowThon is not a hormone is not produced by pituitary hypothalamus. Right. So when you're talking about negative feedbacks and said, hey, I don't want my body to get lazy and not produce what I need to do.

We're talking about hormones. We're talking about something that the pituitary hypothalamus will do it for us. But it comes to the GlowThon. It's not supposed to be an issue because the issue with GlowThon is what we need ATP and NED to produce GlowThon. ATP and NED if we do not produce GlowThon gets what they are do. There's so many different peppers that can produce all day long.

So it's the energy is never wasted to do something else. And even though you supplement GlowThon and we go and supplementation later on, but you're going to find out that none of the supplements actually absorb in your body at all. So if you're just taking a glutathione tablet or capsule or sublingual, you're getting virtually or none of that glutathione.

So none as a GlowThon, the GlowThon levels build rising your body, but not because your body absorbed it. The body breaks down the GlowThon, takes up the amino acids, sometimes two amino acids, one sometimes a single amino acid, but then they will combine back together. But you know, it's interesting. I talk about this with proteins all the time. I mean, most people think that amino acids are proteins. They're actually not. They're the building blocks proteins.

And that if you don't have amino acids in the right ratios, when it runs out of a certain amino acid, it quits the production of an entire assembly line. So balanced amino acid profiles are so important because then you give the liver exactly what it needs to assemble whatever protein it's going to assemble or you know, go to the muscle and help prepare muscle.

It sounds like a very similar action as a play with glutathione because you're saying if you just take the three amino acids as glutathione and you swallow it or you take it in a liplosomal version or a sublingual version or what have your bodies actually not receiving that glutathione, your glutathione production may rise. But that's because that glutathione is being metabolized in the liver, assembled back into those three amino acids and returned to the bloodstream as glutathione.

That's exactly right. Yeah. That's why if you look at the FDA, it's only a food one product ever in the history, which is NAC. They have not approved anything else. So even the ER right now, if you go with a total overdose and you're about to die, the drug of choices, NAC to assist you. Yeah, and assisting to revive you back and all it's doing is producing enough amount of glutathione there.

Is that what NAC is doing? Yeah. I wondered because I take NAC sometimes if I've got like excess mucous or flamm or things, I feel like it kind of drives me out a little bit in a good way. Yeah. And but I didn't know that the mechanism of action for an acetylcistine was to race glutathione. That's right.

That's an indirect way of helping you race glutathione. So then what's what's special about the the transdermal route and what's special about combining glutathione with other molecules in order to actually have that glutathione show up directly in the bloodstream? Yeah, that was the loaded question. It's a loaded question. I just really good question to find that out. My last guest said the same thing.

So when I said the glutathione, it's it. You're right. When when I when I first hired when I'm a first hired, I was hired to work on vibrancy because the data that vibrancy was the best and everybody knows right. And I saw a said, okay, that's not going to work for me. I said, I'll work for you on vibrancy, but personally, I'm going to work on glutathione. Since I use up all my resources I have on working master and toxic glutathione because it was too difficult. Nobody wanted to touch it.

Of gold was to my goal as a pharmacist was just, can I stabilize the glutathione in a water based system outside the human body? That was the only goal I had. I don't go any further than that. And took me about a few years and we we figured a way to literally stabilize the glutathide at room temperature in a water based system that still on my shelf that smells like sulfur. Yeah, it does smell like I just sprayed it on my arm. It didn't smell that good, but it does away.

It goes away. And so that was my goal to first put a chemical cap on the thiol group because that thiol group gets gets oxidized very, very fast. So I had to put a chemical cap on it because if I put any other caps on it, it just destroys the whole molecule. And that's why all this all these eons of research and glutathione. Nobody can figure out what the chemical cap on it. So that was my first patent on that one to get the chemical cap on the group.

And essentially what this chemical cap is doing is keeping the glutathione from denatering before it even gets into the body. Right. So in the suspension in the solution. Right. In the solution stays there all the time like that. And so now I said, well, somebody else will do the research to get inside your body.

Guess what? Nobody did the research. Nobody was going to do the research. So I said, okay, so I told my my PhD on staff with me. I said, Dr. Tran, we're going to work together and try to figure this out on how to get inside your body.

But never in a million years, I thought this was going to be a topical route. Right. Because as a as a pharmacist brain, we've been we've been programmed that to get inside your body, it has to be inside the body, either through injections, through oral nasal spray, supository, something. Nebulizer. Yeah. The goal is you have to physically see you have to physically see it go inside your body. That's the perception that we have about medicine.

It has to go inside the body. And once it goes into the body of what job is done. Now the body you take care of the rest and take it to where it needs to. Right. Right. The body spits it out. Right. Because no, thank you. I know what my body is doing. I know what I need to do. I don't need your help. Right. And spits it out. And so with us, what we did was we we took the same technology that we put the chemical cap on it.

And we somehow figured out how to trap this glutathide molecule and rotate this in a way that can reduce the size of the molecule. And so when we did their part, it's like protein folding almost put in envelope. Yeah. Exactly. Exactly. So we did the part and when we did the part, it started getting through your skin very easily. And now how are you measuring this? Were you doing serum concentration studies? So we're doing red blood cells levels.

Oh, so you're actually going one step further, not just entering the blood that actually inside the RBC. Yeah, because the if you measure the whole blood, the plasma glutathiral level has a very, very short life. Because plasma doesn't doesn't go anywhere. Right. The kidney filters it out and the dumps everything all the glutein in the urine in about 15, 14, 15 minutes is gone.

As early as five minutes as much as 15 minutes is already out of the system. And so it was not helpful for me to understand to have glutein in the plasma at all. So I need it in the blood cells. That's only like a measure of interstellar levels because I don't want to tissue biopsies. Right. So what we figured out that the base that we use is actually binding to the ACE receptors on your cells.

Every cells have lipid rafts. The lipid rafts have ACE receptors. That receptor is the gateway to communicate with the cells. So we use the receptors. Right. If you take a blood pressure pills, they have an ACE inhibitor to block the receptor. So the blood pressure doesn't go up. Right. So we use the same receptor to deliver nutrients to your cells. So this ACE receptor actually pulls it through the phospholibid bilayer into the cell.

And I am an intracellular concentration in the consculpture. And so now when the glutein gets inside the body for the very first time. I mean, that's where the miracle happens. Right. Because when people ask you say, what does it do? Well, what does it do for me? I said, well, I don't know. I really do not know because we have no idea what your body has adjusted to based on the lack of nutrients you have now. Right. And so everybody has different effects.

You know, I can tell you emphatically. It's not not placebo that I use your topical glutathione. I'll spray it four times or so on the inside of my forearm and rub it in. I do notice a noticeable increase in just energy and clarity almost immediately thereafter. So I just just within a few minutes. And I thought it was placebo at first. I don't think it's placebo now because I could vary the time of day that I do it.

And I can actually I'm pretty in tune with my body so I can actually tell that something good has happened in my body. And I don't really know how to describe it other than sort of this elevated lift of just mental clarity, kind of alertness and just feeling clean and aware. Like, maybe it's more cognizant when I'm doing it. Do you have a gene mutation that I do have?

I do have to have to do that. So that's the issue. So most of my most of my clients, they have this gene mutation when they apply the glutathione, they feel the effects of head cleaning up within 15 minutes. Yeah, that's about that's exactly what I experienced. But the energy that you're feeling is I'm homo sagas. I'm homo sagas for MTHFR CC or a 1298 C. I have a copy of the eight 1298 C and also a copy of the C670 70. So I both both. Both. Yeah. So I noticed the good.

Good. That's probably now that I think about as probably a lot of the reason why because the transalpheration good. The pathways are inhibited. That's right. I also notice when I take adequate amounts of methyl folate that I feel better. And I can. I notice the days when I don't take methyl folate. Now I don't notice when I do actually take myself amends does make a difference. The difference is when I don't, you know, sometimes I leave town off get my vitamin tray. And all that.

My wife is very good about reminding me about my vitamins because she says I don't think I have a temper, but she says I do. And she's like, did you take your vitamins today? So she she always actually carries an extra pack with her. The energy that you noticed is ATP. ATP sparing molecule. So so I'm assuming you're on very good health internally. Externally, you look amazing, but internally. We are very good health. And so when you're on very good health. So most of my athletes.

They have the same exact notice, right? They notice the increase in energy, but it's not a caffeine energy. Yes, no, no, it's definitely not. It's the intrinsic energy of ATP getting spared. And when you have spared ATP, my body is fun looking for other things to do. Imagine a house person in your house that is that is a workaholic has nothing to do in your house.

Is that person is looking to do fix something right all the time. Right. So ATP is now spared. Now it has a lot of energy now is looking for things to do in your body. So talk a little bit about. So you developed this about protein folding in this in this chemical cap to. So now you have this delivery system for transdermal. And now once glutathione goes transdermal into the body.

Do you recommend that people take glutathione every day? Every day. You see. Yes. And and when when it goes transdermal enters the bloodstream. It eventually makes its way into the cell. Talk a little bit about what it's doing because you know I, I think I have this same theory as a lot of anti-aging longevity, you know, biohacking researchers theory about aging. And that eventually it's a mitochondrial disease. Right. Is progressive decline in mitochondrial function.

And I don't know that there is much in the world of pathology or disease or dysfunction that you can't trace back to the mitochondria. I mean virtually everything starts and ends with the mitochondria. So if the glutathione is going intracellular. Once it's in the cytoplasm of the cell, what kind of activities is glutathione providing? Is it helping with cellular waste elimination repair regeneration detoxification?

The two things that I know of are most is the is the neutralizing all the free radicals, our species and the conjugating and and removing all the toxic overload repair. I am not 100% sure yet. Okay. Yeah. So this is the first time we have actually gone to the end of the body. Right.

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You can go to echo ECH O H2O dot com. That's echo ECH O H2O dot com. Enter the code ultimate 10 for a discount. Echo H2O entered the code ultimate 10 for a discount. So the research need to start. We need to start now is to try to figure out what else can we do with it. But we know now that it's going to help to sell eliminate waste and detoxify. That's right. Obviously that's clearly a good thing.

I mean, I've often hypothesized that if we don't get rid of the exhaust, it essentially backs up and blows the engine. And I think it's a very overlooked part of modern medicine, even functional medicine is that cellular metabolism is a dirty process. I mean, from a cellular perspective, right? It's a very dirty process creates a lot of waste and you need to take the trash out. And glutathione helps take the trash out. It's the most effective way to take the trash out.

So now in your opinion, so people that are doing high dose glutathione IVs or liposomal glutathione or these orals, I've never believed in oral glutathione. And I've ever actually seen the research on liposomal glutathione, but in your opinion, these are less effective if effective at all. No, they are effective, but they are, it's just that it will be effective in people. They'll have the ability to deconstruct the molecule, absorb the molecule and reconstruct again on demand.

But if you have a gene mutation and take a product that can deconstruct, but they can't reconstruct again, and one of a sudden you have all this waste. Now you're carrying more waste in your body than actually helping you. And the question you asked earlier about chemistry to much of glutathione. Until now, that wasn't the case. You can literally, I have doctors that have injected 10 grams of IV push of glutathione for Parkinson's patients.

Right. Right. 10 grams is, it's a barbaric dose for topical version that we have. If you have to give everything goes into a cellarly, I mean, your body will not be able to tolerate that. That is like crazy amount. But yet they have been giving this high dose. Why? Because the body breaks it down, system gets reabsorbed, and system has been used to produce glutathione again.

So all of a sudden, it doesn't really matter how what dose you give them. It's only doing is just increasing the amino acids in your body and allowing the body to reproduce the medications for yourself. Like you have, you take, you take methylfolate, why can you take folic acid? Because folic acid has to come into methylfolate to get absorbing your body.

That's right. And folic acid is what your body can use up, but what it can use folic acid. But guess what? The pharmaceutical company has been giving us folic acid for 100 plus years. Right. Right. It's useless drugs. Right. It's useless drugs. It's useless and quite frankly, it's in my industry, when I was in the mortality space, we would see people that had chronic anemias.

And the frontline supplementation for anemias is iron B12 and folic acid. And they would give them iron B12 folic acid, iron B12 and folic acid, iron B12 and folic acid. And the iron levels would skyrocket, but the anemia would never go away. And when they would switch to methylfolate, simple switch to the methylated form of that nutrient, boom, the anemia would go away right away.

And I think that, you know, this touches on the point that, first of all, you know, methylation is very important in human body. And that secondly, you know, we sometimes assume, in my opinion, that, and I think it's a very dangerous assumption that all human beings are treating vitamins, minerals, amino acids, nutrients the same way.

And we're not, you know, what goes into your body may be methylated very differently than what goes into my body, which is probably why I feel energy from the glutathione, you might not, if you don't have the MTHF-R gene mutation. And it's estimated that what, 44% some even as high as 60% of the population has that gene mutation. So they could really benefit from the lithium.

That's what you're saying. Wow. Now, now, can you, can you put this, what are, aside from cellular waste and detoxification, what are some of the other benefits of glutathione? I know that it's used cosmetically to lighten the skin. Well, the cause, so keep in mind, your skin is the largest organ. It's exposed to the amount of toxins the most. So, as a skin is an organ, it's pretty toxic.

And we try to eliminate, you do sauna and you do all this therapies to remove all the thalates out of your skin all the time. You burn off all the excess gas. So skin needs nourishment. The issue is if you take glutathione internally or whatever forms, it goes into your blood first and goes to the rest of the body and then eventually come back to the skin again. So the fact that we apply glutathione on the skin directly is so much beneficial because it helps you to skin immediately.

And so again, that was a side project. I said, hey, you know what? If I'm going to help with people with glutathione, same technology, I'm going to use everything else and use the glutathione. What I'm going to see is all the things that I know of and make it into some phrase screams so that my guys and girls that enjoy what you do.

Oh, no, I know they're all listening to this now because I mean, I won't say that I'm by far a skincare expert, but I don't know that I've seen glutathione in skincare products. No, because there's no absorb. No, no, no, no, I should take it back. The plenty of glutathione products in the market for skin, nothing works. Right. Nothing ever worked for this one until we get the technology to do.

And do they use it for skin lightning? I mean, I just know the pharmacy that we do that we do business with. I've never used it and I don't think our clinicians ever prescribed it, but I see it on the on the pharmacology list there that glutathione and the indication is for skin lightning. Is that it? So that's something that came out of the Asian market and they'll be injecting glutathione with vitamin C every week injections for skin lightning. And it worked. It does work.

And so but I would someone want to lighten their skin. Well, what vanity or is it? Well, why would somebody want to darken the skin? I guess that's a good point. So people that are fair wants to darken the skin. People that are dark. They're dark. They want to lighten the skin. No, nobody's happy with nobody was happy with what they have. So somebody that's really dark pigmented could could use high dose glutathione and vitamin C to actually lighten their skin.

Well, the thing is what they're really doing is the body, all the melanin. It's a sort of it's not a healthy way to lighten the skin. Okay. When you use topical glutein. It didn't seem. It doesn't seem healthy. Yeah, I didn't see. So the topical version what it's actually doing is is removing all the debris out. So if if you have those oxidized lipids on your skin that's coming out of all the dark spots. And when that goes neutralize, the skin gets all fair.

So that that I'm okay with it, but I am not okay with burning the skin burning the melanin to make it lighter. Right. And so that's not fun. And when you combine these things, let's say that someone's using a transdermal glutathione, but they're also using a topical glutathione skin care. Are they overdosing on glutathione? Because I assume it's the same folded protein in the topical skin.

So when when people buy the products from us, both of them, then we always send them the videos to say, okay, you can use both products the same same day, but make sure you don't double up on the dosages. So if you have skin care, then skip the topical version for that evening and then use the topic in the morning, well, there's no morning skincare glutathione there.

How we when we look at blood biomarkers when when our clinicians are prescribing glutathione IVs, one of the main markers that we look at is alkaline phosphatase, the AST and ALT enzymes in the liver. So looking at inflammation and irritation in the liver and looking to lower those enzymes when the liver is understressed by using hydrosis glutathione, and I will tell you we have substantial albeit anecdotal evidence that it's very effective.

Because we'll pull labs on patients sometimes 10 to 12 weeks apart and we'll see patients with severely elevated liver enzymes and they respond very well to glutathione. But what you're telling me is they're not really responding directly to the glutathione they're responding to that person's the that person's liver's capacity to actually reassemble the glutathione. That's really what's happening. But what you're saying now we can remove the middle man.

We can we can remove the liver and deliver it directly to the bloodstream. Yeah, liver so much jobs leave my loan. Yeah, yeah, it's got a lot to do trust. So I say just give it to the glutathione to the liver and again when you said that earlier about what's what's the max dose can you give too much of glutathione. When I used the doses topically about the IV doses I was using before, I have so much reactions in my patients.

I said, oh, we're going to stop it. So that did me on a rabbit hole for a few years trying to figure out what dose to give how much to give how often to give to all the PK studies we had to do to make sure how much glutathione to be give. We found out that most people only need about 100 to 200 milligrams per day or two or two a day. That's all they need.

100 to 200 milligrams a day, um, trans journal trans journal. Okay, compared to to the 10 grams of IVs. Right. It's barbaric. Right. And I've he's not practical either. I mean, yes, you could do it. Once a week if you really want to do once a week or you know every other week or once a month, but it's like the big high high dose any D drips.

You know, I think you're better off administering low doses of any D on a daily basis that once a month going in for a thousand milligrams of NAD into in this four hour six hour IV unless you have something specifically going on at that time that you're trying to address.

And I'm okay with IVs if it's working for you, but if it's not working for you, right, then why do it? Right. Or if you can get the same treatment done at your own home in 20 seconds, rub it on and you're done and go go about your day, well, you spend three hours in a doctor's office and get your IV stand.

It doesn't make sense. It just doesn't make sense. And so when you do the topical version, it is it is literally helping patients, a limit all those issues that you're talking about deliverance, I'm a ST, the ALT, the AlcFOS, all those things. Right. We have seen you know, you know, patients reporting to us about about having those changes being noticed within three to six months, well, six months is kind of too far. Right.

But within three months is one of them. We're doing it 12 weeks, but here's the thing. How many people have Nash or NFL D or cirrhosis today? It is skyrocketing and they're predicting that over 50% of the world's population is going to have this by 20, 40, 20, 50%. 50% of the world's population is going to have NFL D or Nash something like that.

Something to deliver. Well, it is it is not an alcoholic fatty liver disease for those people that don't know what NFL D is. That's that's the, you know, which I didn't know it was that prevalent. But I will say that you know, even in our own patient population, you see a rise in fatty liver in patients that do not drink alcohol or certainly don't drink it excessively.

And I think that link is being dispelled now that it's it's not just high consumption of alcohol that that's causing this non alcoholic fatty liver disease. I mean, toxic toxic is in the environment is is rampant. So when you see that and you see the liver enzymes high,

the liver that comes back to normal and you think you're cured, right is further away from that further away from that. Just because the liver enzymes are normal, that is just the inflammation is back to normal. The liver is still toxic. So it takes if not months, if it takes a couple of years to completely clean it out.

And really, so it takes a long, long time to do that part. And and so we are very fortunate to be working with few clinicians in my neighborhood. And we are we are helping a lot of patients try to try to clean the liver out by by. So I mean, talk a little bit about I know that you do a lot of lecturing on on pharmaceuticals, pharmaceutical drug delivery routes, but talk a little bit about, you know, what's what's kind of inspiring you right now research wise with glutathione.

Or anything else for that matter. I mean, now I'm this is sneak peak what I'm working on right now. So two molecules that is I'm passionate about right now, one is NAD. Because now if I can if I can deliver NAD enough in a in a more active form. Oh my gosh, when you say more active form, I mean NAD is NAD is NAD right it's NAD plus is in the reduced form, right, which is why you can't take it orally. That's why because it just neutralizes that.

That that the plus that you see on the back of NAD. So people take nicotine might rob aside nicotinic acid NMN nicotinomide mononucleotide, which I think you know, Dr. Sinclair has done a great job of popularizing. Along with his is a glucophages like metformin. You know, I think my preference would probably be burbering, but but.

So talk about some of the promising research on NAD for that matter. I mean, my understanding of NAD is you can't take it orally or sublingually right because you the reduced form becomes non reduced. That's you can inject it. Well, inject is one one way of getting to the system. But again, my delivery system is my product is stable in my lab for almost four years now. So I have a stable product now stable NAD NAD.

In my lab. Only thing I have not figured is does it go topically sublingually nasal spray now that's my next research phase right now. Right. So when that when that comes out, I'll have access to my few doctors first. And NAD, you know, I think faces the same sort of stigma that if you if you put too much NAD into the body, would you reduce your own production of NAD? I'm guessing that's true also.

I would as well. And again, I don't have any any randomized clinical trial that I'm aware of to prove that. But, but so I think in in small doses or in boldest doses when you're when you're facing a viral pathogen or something seems to make a lot of sense.

But as a supplement to extend life, you know, knowing what I know about the crebs cycle and electron transport chain and the mitochondria, it seems to make a lot of sense because you know, NAD's role in in mitochondrial health is very well documented. I guess the question becomes can you overdose with NAD or or can we even get any idea effectively into the body through some other mechanism?

Well, that's that's what we find out because if you give an R or NMN or something like that, it's it's okay because your body's steaming those own production. So if there's a great limit step by the bodies is working on to produce itself. Right. So you're not going to overdose overdose. But when you give NAD straight up, there's a potential overdose and that's the same thing with the other side.

I have to do the work early on. That's what the lease will not be there fast enough. Right. But it's it's in my works to get that one. But next, my next few products I'm working on right now is I want to get those two, three, four, five amino acid fragments. There's a billing blocks. So the while it doesn't have to work so hard and use a billing blocks like Lego pieces and make make proteins and things like that.

For different parts, if you have bone needs help of the bone fragments and skin fragments and so you could actually do, you know, ideally a trans dermal supplement for bone repair or for enhance, you know, muscle

and ableism or anything anything and all the small mobility. So basically small peptides is what I'm what I'm more interested in your work with NAD. Are you trying to isolate and as you have a stable NAD product and now the question is the delivery pathway because I mean, I don't think I have a stable NAD is that or shattering having stable NAD that could be administered in a non intravenous route would be pretty astounding. So the NAD is only stable for a few hours.

The fact that we have stable for for over here two years now. And is this is this in cold temperatures or this cold temperature. So like a refrigerator or a refrigerator. And so you stabilized it for several years and you're working now with different mechanisms of delivery. You think you'll ever get to a trans dermal NAD because I have seen the NAD patches now that you put a strap on you soak it with NAD and you put this patch on your arm. I forget the brand name of it.

It was it was suspect to me not because I know anything about their science and I will say that if you know the brand. I won't mention it on the air. But just my my human biology meter went up a little bit because I thought you know that there's so many impediments to getting things trans dermal that I wondered if the patch was just, you know, sort of mostly drying on the skin or if it was actually delivering NAD. If you have to soak up and put some occlusions or all kinds of things in there.

It's trying to drive it because there's a lot of barriers in your skin that is allowing you to penetrate inside. Right. When you use to you have a use barriers to on top of the product to kind of force it in there. It's only going to happen so much. Right. And so that's what my my concerns are. Like when you're like, you just goes in like this. Right. I do notice it's I mean, it's a little sticky right after I apply it and then it's just gone. Yeah.

And then when I touch my skin, I can't feel that it's even there. I can't smell it. It was already gone. Everything. So that's what I'm looking at right now. Every time I apply it like if you'll play a whole more cream. If you play just a shot or all our restriatures or whatever, we'll play the cream. It's there for a day. Right. It's slowly, slowly seeping in through the to the lipid layers and all those things. And so the skin is a gigantic barrier to get inside your body.

Right. It's one of those things that we warn women about our OB-GYN Dr. Sardis warning women about it all the time that that you know when they have a young. Well, when they're nursing, we don't put them on hormones, but when they have young children around, especially if they're holding the children alive. I mean, those hormones testosterone is the main one that they're putting on topically. They're going right through the baby's skin and right into their body.

And they can cause toxic reactions because you're talking about putting an adult dose of babies. Transtermal hormones. Yeah. It's crazy. And so we want to make sure that any disease that I make, it needs to be effective and has to get into it. If it works, great. If it doesn't work, that's okay. I have other parties to work on. And your background was a pharmacologist was in drug delivery. Is that right?

So it happened to be drug delivery. It was not my major was pharmacy. I was a clinical pharmacist, designed drug protocols for my celebrity clients and doctors. I usually train my doctors and work with them to help their patients. So that's why I do full-time. So they come to me and say, hey, I have this patient so and so with this issues, give you the hormones, give you the endocrine hormones, give you the nutrition plans.

And all the medications that are taking can make a complete package so that if they have a beta or a duplicating drugs, making sure it's very, everything is streamlined and see what the plans are. So that's what I designed. But when it happens is that all my clients, they're very high, high-neutral individuals, are looking for little more than what they're getting. Right. So are all of mine.

This is not enough. This is this is just barely cutting the mustard. Right. I need I need something that is better than what this is. And so research is now I'm spending a lot more time in research now and trying to figure out products and molecules that the people are looking for. And I want to deliver them in a more effective way because injecting products is just getting too complicated.

And we've noticed that too in our clinics that the oral route of delivery is in a lot of cases is kind of a crap shoot. When you look at the oral dosage versus the serum concentration in the blood versus like when you do a cellular nutrition assay, you're seeing how much of it is actually going through the cell membrane and actually ending up in the cell measurable in the cell.

Different which we've honed in on with methylation different forms of B12 based on your methylation will have higher intracellular concentrations. When you do these methyl detox profile tests and then you combine that with a cellular nutrition assay.

So one is measuring how much is getting into the blood and the other is how much is getting into the cell. You know, we see that you know all forms of B12 are not the same in terms of intracellular absorption forms of full late and full of acid and its precursors are not the same in terms of their intracellular absorption.

So, you know, now that you have this stable NAD molecule, I guess the next thing is a figure out how to get it into the body and then to somehow be able to measure, you know, what's its utilization. Yes. And so talk a little bit about the role of of NAD in the body because I think everybody else kind of heard of NAD and they know it's like a good thing. Yeah. What does it really do?

And that's the part I have not dwell too much into it personally myself because again, first I need to figure out can I make this product. I know that it's big enough for me to work on it. And once I figure out how to get the body, how to get the body into the system, I'm going to look at each and every chemical pathways that is affecting and see can I do some studies on those pathways to making sure that okay now I know that it is getting into the system.

It's every chemical reaction, look at the whole Krepp cycles, there's everything is Edd, Edd, Eddph to Edd, everything. Yeah, no, it's all that oxidation, that reduction reaction. So then, you know, then talk about, you know, glutathione as the major antioxidant in the human body, what other implications would drive somebody to need additional glutathione? Are there medications interrupting our pharmaceuticals, certain pharmaceuticals interrupting our capacity to either generate and

glutathione or the interrupting the glutathione pathway. So if I was a, something listening to this podcast and I was on XYZ medication, like they say, if you're on a statin, you definitely need to be taking coq 10. Yes, because statins will reduce the coq 10 and so you should therefore supplement with it. They say if you're on methotrexate, you should be taking full methodfolate, yeah, or, well, they say full of acid, but really methodfolate because they don't know how to set pathway.

So what are some of the, you know, common pharmaceuticals that people that are listening to this podcast might be taking that would give them even more impetus to take. So glutathione, all the medication that goes to your liver, so you're pretty much everything, pretty much exactly what I'm saying, all your blood pressure pills, all your hormones you're taking both the gravel hormones is a little bit

too, too, too, too, hormones and depressions that you're taking. So ground hormone, so, so like the somagletides and the two zepatides, those, those GLP1 and GDP inhibitors, that's a whole different animal. So if you're thinking about the semi-glutides, all the GLP1s, what's happening today is that these people are losing weight, they're losing the adipose tissue. Adipose tissue is actually sequestering all your toxins in your body, and holding it, and now we're letting it go.

Yes. Imagine that you go out on the streets and the garbage guy is not coming up and all the trash is on the streets everywhere now. Yes. I warn about this all the times in these rapid weight loss patients, you know, a lot of them end up getting quite sick. You know, I mean, just when I say quite sick, I mean, not deathly ill, but just these prolonged flu-like symptoms while they're experiencing very rapid weight loss from the release of these toxins and the fat cells.

That's what we do the time to conjugate them and kind of sequester them back and just dump them into urine and intestines. But to make that happen, they got to drink lots of water, make sure they eat fiber, they had to have the proper diet. If you're eating the senamerican diet, SAD, they need GLP1, I'm like every... Yeah. I guess today. But if they need SAD diet, then they may not be able to afford GLP1, and the first place.

Right. They're still eating the food pyramid with lucky charms at the very top over grass fed steak. So, anyway, so those are things. If you're using those toxic cosmetic products, that's another issue, too. So there's so many things. Yeah, there's, you know, I had an interesting conversation about the toxic cosmetic products the other day with Dr. Barbara Stern.

She's an MD. She started Dr. Stern cosmetics. And her whole idea was to, you know, get these non-toxic cosmetics out to the marketplace. But, you know, she said something very interesting to me. She said that, you know, all these young, especially girls, are shopping at Sephora.

And they're growing up, and they're pre-pubescent. So, they're either pre-pubescent, or they're just entering puberty. And a lot of these endocrine disruptors and hormone disruptors that are in chemicals and synthetics that are in these makeups that are highly unregulated are having demonstrative effects on these...

Yeah, you understand. If it's able to affect a young, non-mentraiding female or having them start to a menstrual cycle early, I mean, just think of the effects in adult men and women, too, for some of these topicals. And so, are topical cosmetics, you know, are those not only increasing the need for glutathione, but, you know, what is your feeling on a lot of these topical cosmetics in terms of their hormone disruption or endocrine disruption?

So, a lot of the cosmetics have removed the endocrine disruptors out of the system, because the clean beauty is everywhere now. People are putting the ingredients list on the famous search engines. Yeah. Okay, I'm not going to take this chemicals, because it's not going to be healthy for me. So, they're doing their part. But what you're talking about are those young people, they cannot have the resources.

They're going to those favorite mass marketers and buying the fancy creams that cheap, but don't have the clean beauty sticker on it. Or something that they have not... is not familiar by pharmacists that understand the chemicals. Right. And so, it's there, but it's getting less and less. If you ask me the single 20 years ago, I will tell you, oh my god, you're a huge problem.

Yeah. What are some of the things that moms and dads can look for on the back of those labels that they don't want their kids putting on their face? Some of those like retinets or... So, my biggest pet peeve is anything to do with the retin... retinets, retinol. It is very toxic to young girls. It's very toxic. I mean, you don't get whiteamine A to anybody, young girls, especially if they're going to get pregnant.

In fact, whiteamine A is something... in the pharmacy, we do... do you pregnancy test before you prescribe it to you? Wow. Is that toxic? But the retinol has been used... like everybody uses it. I said, I see it in everything. It is toxic. Yeah. So, you think that these... a lot of these retinal creams are... those are things to be avoided because they're direct endocrine disorders. They are. Then we have also have the quinones, the hydroquinones, the skin-likeening agents.

Yeah. Even though they are... Seeing a lot of those can get them in Costco and like... Bubs, really. Yeah. Like a Mary's jaw. Yeah, yeah, yeah, yeah, and just slather it on your face. But I think what we need to do is... we need people like you to educate. We need people like you to bring this out to tell people that, hey, look at these things. Yeah. Don't take my word for it. Do you own research if you have to?

So, as an offset to some of these like chemical salts. And I'm a huge believer that the dosage does not really determine the poison. Sometimes the cumulative dosage, just the poison that sometimes... something may not be toxic in a given dosage like cyanocobalamin. The, the, the... The cyanide-based, form of B12. But in cumulative doses, it can certainly have a detrimental effect.

Especially when you look at the detoxification pathway. Like, okay, well, one thing is how does this get into the body? And the second thing is that there is very often overlooked is how does it get out? What are the byproducts of methylating this nutrient and then how does the body rid itself of those byproducts? which should further support the need for excess glutathione.

And so in your opinion, a daily regular dose, 200 milligrams of glutathione applied topically day or even day and night is not gonna have any long-term detrimental effects on endogenous production. So that comes to a very good question that you asked me right now is, and this is something that I've been pondering on for a while now, because when you ask a question, can your body take too much glutathione? And the answer is no, until the topical version came in.

This topical version, if you take too much of it, it's straight available bio-below to your body. So your body can actually go from a oxidistress state to the opposite, which is reductive state. And so that is not healthy. That is not healthy at all. You say reductive state, what does that mean? There you go, because you have never heard of it before. Because it doesn't exist. It doesn't exist. There's no medication in the world today.

They can put your body from oxidistress state to zero oxidation, zero. Now, I mean, when you go to that state, your body becomes very lazy, becomes reactive. So that's where you get rashes and itching. And so it is not a healthy state to be in. The reduced state. So the question is, can I get to high enough, but not overboard? So that was my first research, because that's what I first found out. I said, hey, what is this happening? Right? So I need to figure that portion out first thing.

So when I say 100 milligrams twice a day, or 2 milligrams twice a day, maximum dose, it's because at that dosage is, I'm getting your RBC laws of glutton to high normal, but it's not going overboard. It's like, for example, testosterone, testosterone is from 250 to 1,100, but the guys are taking enough to go to 1,500, 2,000. Right. You can do that with glutton. Right. Because if you get too more, the body flips out. Right, because it literally is just pulling too much out of the cell.

Yes. And it's not healthy at all. And the body gets into hookshimer reactions. And so we, most of us have a very difficult time meeting our protein needs and certain protein sources like way protein and others can be as little as 20% absorbable. This is 99% absorbable, and it has all of the essential amino acids that the body needs to build lean muscle, to recover, to improve our exercise performance, and most importantly, to repair after we have intense exercise.

So this is called perfect amino by body health. It's, like I said, 99% absorbable. It only has two calories. Eventually, the caloric intake has virtually no caloric intake. It will not break a fast. It tastes amazing. You mix it in water. I take this literally every single morning. If you're working out in a fasted state, you have to take a full spectrum of amino acid prior to your workout to preserve your lean muscle and make sure that you're recovering properly.

And again, it will not break your fast. So the caloric impact is virtually zero. You get all the full spectrum of amino acids. It tastes wonderful. I use it every single day. You can go to bodyhealth.com forward slash ultimate. That's bodyhealth.com forward slash ultimate and look for the perfect aminos. They actually come in capsules if you're on the go, or it becomes in several flavors that they make in a powder, which I love. It's flavored with natural means of flavorings.

There's no artificial sweeteners in here. So this is one of my absolute favorite products. Give it a try. If you're working out at all, you need a full spectrum of amino acid. Go to bodyhealth.com forward slash ultimate. That's bodyhealth.com forward slash ultimate. I love their lab tested products. You can actually see the absorption rate for all of their products that got great electrolyte protein combinations. My favorite is the perfect aminos bodyhealth.com forward slash ultimate.

And now back to the ultimate human podcast. So this is why we, if you stick to the dosaging, then you'll have a problem with it. And you can take it for rest of your life and know issues whatsoever. But the only time it happens is when I have a lot of clients, they think that, oh, Glutton, if this is that good, I don't take more. Yeah. Everybody feels the same way. They do the cold plunges. They do it with everything. Yeah. Like these guys get in 37 degree cold plunges underwater for 12 minutes.

Yeah. To get the sauna as hot as they can possibly get it till it's almost third degree burning their skin and they're staying in there for 40 or 60 minutes. It's like more is not necessarily better. Some of these treatments are meant to be like guardrails. A little bit of cold shock can do the body phenomenal, good, and a little bit of heat shock and do the body tremendous, tremendous good sweating.

A little bit of oxygen, but not too much oxygen, a little bit of red light, but not too much red light. A little bit of sunlight, but not overdoing it and sunlight. And Glutton, I don't know if he appears to be the same thing. And how soon can someone start taking Glutton, I mean, can you take Glutton if you're a child? Or is it weight dependent? It's like an absorption issue.

So we give to young kids like one month old babies we have done in the past, but both the time if you're under the age of 30, your body is able to keep up with the demand. Okay. It's able to keep up with the demand. Unless you have disorders where you have a gene mutation, we cannot conjure Glutton, then those are people in another spectrum disorder. Those people are going to need lifelong therapy with Glutton. So those are different.

So you're even saying spectrum disorders because autism is, as I understand it, the intensity of the spectrum is somewhat related to the amount of neural inflammation. And obviously if we can reduce neural inflammation, that would be a good thing in all of these kinds of conditions like autism. And ADD and ADHD and Alzheimer's and dementia and any other neuropathic condition of the brain, I would assume can benefit from reduced neural inflammation.

But are you saying there's a special need for those people that are autistic or might be on the spectrum sort of state? Any spectrum disorder, I'm going to give a plug to Dr. Joseph Maroon. He's a chief neurologist at Pacific University. He's a team doctor for Pacific Steelers. Okay. So he's going to be next on my podcast, by the way. We've been working on him down.

We've been working with him on this glute, because this is the only glutein that has shown to improve blood, across blood and barrier to show some positive results in patients with concussions and... OCTs and traumatic brain injury. And so I mean, if Lister's out there looking forward, please help us. We're looking for funding to NIH, because we want to go through NIH to do the clinical trial to see if we can brain map the glutein. Completely. Wow, so you can actually... We have a patent.

There's a guy who was a patent or a system where he can do the brain mapping of glutein levels without a needle. It's just a scanner. Wow. And so we need to scan some picks up those three amino acids. No, glutein. That's what I mean, the third is the glutein. The glutein itself. Wow. And so if you see a hotspot in the frontal lobe, and that's the cause of Parkinson's, wait a second.

If I can get the levels up to hide up to the frontal lobe, is there a possible that I can reduce the chance of Parkinson's? Can I treat it differently? What dose would I give? How often to give? How much I give? So, I mean, we would love to do those kinds of work next as well because we've seen the results. But the results are too sporadic. It requires a formal trial to figure out what needs to be done.

And if then we can predict Alzheimer's dementia, Parkinson's, ALS, I mean, there is no treatment today for any neurological disorders. Right. I mean, there's management, but no real. There's nothing. Yeah, we don't know anything. Absolutely. At this point. Yeah, there were really managing symptoms. So, what's astounding to me is that the amount of conditions like this autoimmune, even specifically where we label the immune system as being dysfunctional. Like it's turned on the body.

You know, colon disease, it's attacking the colon. And, you know, then chagrin's is attacking the lacrimal gland. And, you know, Hashimoto's is attacking the thyroid. But the question is, why do we have such a parabolic rise in these autoimmune conditions? You know, we just having a parabolic rise in the humanities immune systems breaking down. I don't believe that. I believe that the immune system has always been in majority of cases, properly functioning.

It is just detecting some kind of pathogen, bacteria, microtoxin, heavy metal. I mean, I just read a study on heavy metal toxicity and Hashimoto's and how there is an enormously high prevalence of metals within the thyroid in patients whose immune system is attacking the thyroid. And maybe it's not actually attacking the thyroid. It's actually trying to get to the heavy metal. And it's just trying the thyroid tissue in the process.

What kind of implications does gluteothione have for autoimmune conditions? So for the autoimmune, the main thing we would be doing is if the causing agent is something that glutein can conjugate and detoxify. And what is it really good at conjugating into toxifying? Heavy metals, for sure. Good at ion. Yes, really. So we had done a 34-patient trial. We were hired by this company on Japan. They wanted to do a high-malod detox. Japan has a lot of metal toxicity in today's state.

And so they wanted to do something with glutein to do detox studies, of course, everything passed. Only thing they did not pass is hose would apply this sticky stuff on the arms every day. So they kind of... I would if I had heavy metal toxicity, especially in my brain. I'm bathing it, you know? Exactly. I guess they did not like the idea. They were trying to figure it all out. But it worked for arsenic, mercury, cadmium. We could not figure out aluminum. And we could not figure out lead.

But these three were... Mercury is right up there with the most common heavy metal toxicities in the world. And so it was able to help to methylate out the... Have you thought? They saw an increase in the urine extrusion of all this heavy metals. Wow. With administration of 200 milligrams of this transfer of the night. How do we lose twice a day? Yeah. 100 milligrams twice a day. And do you have any other specific indications for it that you've done randomized trials on?

So we have only done one randomized trial. And the trial was done. It was an IRB approved in California for this absorption. And what they were to do is they thought that if... If you say this is this powerful, I want to see can you get rid of micro bacterium? There's no cure for micro bacterium, avium at this point or tuberculosis, anything. Any micro bacterium, there's no antibiotics for that, right? They do one year long treatment for an biotic, and hopefully it'll go away. Right.

They do a test every year to see if it's there. So it was a three day trial. Three day trial. Three day trial? Three day micro bacterium. Yes. And what they found out was they... A private glutton over here, they drew the blood in one hour. And in four hours, the load went down for micro bacterium. No. It started in a biotic.

But what happened was they saw a rise in all the interleukins, the IL-2, the IL-12s, the TNF alpha, interverangam, all the cytokines, they're pro-inflammatory, to help to act with the macrophages, to co-get the bugs and get rid of it from your body. Right. We saw it in one hour. Wow. And so that was published, that was published last year in the Journal of Antioxidant. And people could not believe it was just a three day trial, because in three... What are you gonna see in three days? Right.

We need a three. We only need a three day trial. We only need one day. Wow. And one day we saw these results coming in. This all reduction of the MD, which is oxidized stress markers, we need four hours. Wow. So someone could expect that... I mean, again, I don't... It's certainly don't want to put words in your mouth or overplay the role of good to thion. But as a strategy for healthy aging, for longevity, for those people that are like, I want to be as optimal as possible.

It's a safe dosage, what's a safe amount of time to use it. And without knowing intracellular levels or your methyl-method detox profile, what's a safe protocol for somebody that says, all right, I like what I'm hearing. I mean, good to find certainly something I want to add to my regimen. So I would suggest everybody to... If they have no conditions whatsoever, they're otherwise completely healthy. And I realized the little issues here and that this is a big deal.

If they don't have major conditions, 100-minimum or the literal force-price twice a day is a great starting and ending dose. Okay. Because he's just getting enough every single day, twice a day to keep on helping your body slowly, slowly getting off all the toxins out of the system. I mean, we know that... I talk about this all the time, how cancer is essentially a metabolically healthy cell shifting to a metabolically sick cell. It's becoming metabolically sick.

And there's evidence that metabolically sick cells can actually be reverted back to metabolically healthy cells. It certainly don't want to make the stretch that it's anti-cancer, but it would seem to me that healthy detoxification pathways, healthier waste elimination, I'm talking about cellular waste elimination, healthy detoxification from glutathione would result in less sick cells, metabolically sick cells.

And again, we do work with a lot of oncologists and they've been using some protocols here and there. But I've actually heard not to use glutathione if you're an oncology treatment because it will protect the cancer cell from the... That's a theory. Okay. That's a theory, because again, no glutathione was ever invented to intercellular levels anyways. So that's just a theory. And again, we don't prescribe anything.

So they have to be working with their own oncologists to make sure that they're working for them. I mean, we had some great success stories. This is all in patient of one patient here, one patient there, but they're coming up with the stories of one lady had a stage four cancer spread to the liver, 2% survival rate. She's a physician herself. Wow. 2% survival rate prescribes so much chemotherapy that if the cancer did not kill her, chemotherapy will kill her. Right.

That was how much was prescribed. And so she asked the doctor, and said, can I take glutathione with it? Because the doctor goes, hey, you got 2% survival rate. You get to do what you want to do. Right. So she used the product in conjunction with all the chemotherapy. What found out was after 18 months of chemo, she had no side effects from the chemo. And traditionally, she's cancer-free. Wow. Because of the chemo.

The thing is, how many people get to see on the other side of chemo healthy functioning with no side effects? So that was something that was very, very different and unique. So again, this is not a chemo drug at all. It's not the help with cancer. I don't think so personally. But there's a potential that if you work with oncologists, that there's a chance that you can work in conjunction with other treatments to see if you can protect the other cells. Yeah, of course.

Because I mean, I would imagine, I mean, chemo therapy is not just damaging to cancer cells, it's damaging to, yeah, it's toxic to all the cells. It's why people lose their hair and they become very frail, muscle waste and appetite. Neuropathy. Yeah. Neuropathy being a big one. And in post-oncology, do you see that glutathione is helping accelerate the return back to normalcy by helping to with? So what I can see physically is, you know, if somebody's a chemo, it's chosen as a skin.

This becomes completely lathery like this. Yes. It's very flat. And you can see, you can tell that this person wasn't chemo therapy drug because the oxygen stress is so high that there's no collagen production in your skin and your face, everything is gone. No collagen production. Yeah. It's just damaging your skin as an organ completely. Right. So when we give the glutathione, I start seeing all the pinkish you coming on the face and this side glowing better, the feel better.

So that visually, I can see that part. What's happened? Certainly, I do not know. But visually I do see that part. So that was the early on for me to design the skin care line force for people they were using for chemotherapy because I was using post chemo patients to use this product for them. Because you got to go really direct to the skin because you can't really trust the internal route. Exactly. Because it's been so damaged from chemotherapy, especially if I had radiation in that area.

I know. Several patients that I've had a radiation in the throat region and the outside of the skin is badly damaged. That's all oxidative stress. And growth is the perfect medicine to reduce oxidative stress now. Yeah. I love the, I use the analogy all the time of, I'm plant biology when we fix the soil, the nutrients in the soil, the plant heals, the trunk, the leaves, the branches. I use that analogy all the time.

I feel like we've kind of stopped thinking about human beings this way that we've lost a lot of faith in humanity and mankind, you know, the body's ability for the brain to heal the body, for the body to heal itself. And I think we rarely try to support healthy waste elimination and detoxification. And I mean, at a cellular level, when we're talking about pathology and disease, we're just so narrowly focused on what the pathology is, what the disease condition is.

And we don't look at the consequences of the body's own waste elimination pathways being compromised. And I see very little downside as a human biologist in supporting healthy cellular waste elimination. Because it's been in green in our minds that us in America, we're gonna solve world's problem. We can solve the body's problem. The body says, no, I can deal with my own problems. Just give me the nutrients I need, now take care of it. Don't give me medicine. Don't fix my problem.

I can fix my own problem. And that's coming from a pharmacist, right? I'm sorry. Well, you're not very popular in your profession. No, that's why you never see me that we had the count of working with pharmacy anymore because they'll, I'll point. Not a lot of keynote speeches coming your way from the pharmacy conventions. I do do a few speeches, but not for, not I teach people on how to think outside the box.

Because I tell my pharmacist, I said, you, if you want to progress in your profession, you gotta help people get healthy. The drugs today, we have 3,000 plus medications in my pharmacy today. Wow. None is helping you solve your problem. They're managing your problem. Managing your symptoms. But they're not solving anything for you. Yeah. And that's why my book says the Glutha revolution, why?

It is truly a revolution because if you understand what Glutha can does, Glutha is just empowering your body. It's just empowering your body to do it and what it's supposed to do. When you do that part, you're not solving the problem for the body. You're just giving the ammunition. So the body's going to do everything on its own. You're just, hey, just feeding them with the nutrients that the body needs and just sit back and relax and enjoy the body.

Yeah. You know, I saw a talk from, I want to say it was the age management medicine group conference. I think it was an internist that spoke at the age management medicine group conference that broke down just what you were saying about pharmaceuticals by category. If you were to broadly categorize them as disease maintenance or disease management and symptom maintenance, you would encapsulate 99% of all the pharmaceuticals on the market right now.

If you were to then look at cure-based outcomes, you would have less than 1%. Are designed to completely stop and those were mainly the antibiotics. Pharmaceuticals that were directly related to a specific pathogenic infection. I don't know how much truth there is to that. I haven't looked at statistic up myself, but even if it's anywhere in that realm, it just shows you that our focus is on maintaining a disease state, but managing the symptoms from that disease state.

We don't take metformin or insulin to stop diabetes. We take it to manage diabetes. Is it consistency? And most people are managing their diabetes for an entire lifetime. And the reason is because is... Reversing it. What we have found out is in the medicine is that we see one enzyme and say, oh, if I blocked this enzyme, if I blocked this pathway, I saw the problem. But if you don't know that this enzyme is gonna be in till of the reactions. Right. Very biopically looking at this enzyme.

Yeah, I mean, I often said that some of the worst research in my opinion, down on human beings is where we study things in isolation. Right? And we isolate one redox reaction or we isolate one enzyme and we say, based on this finding, when I put it back into the human body, it's gonna behave exactly like this. That's it. And it doesn't. And unfortunately, I'm not hit a bad mouth compliment at this point, but I'm just telling that... No one in my audience will take bad mouth in the government.

But... But FDA is looking at the approving drugs based on outcomes for particular diseases. Yeah. And so there's no nutraceuticals as FDA approved product, but you have to be attached to a particular outcome. So they can see, if you get this outcomes, fine, I'll give it to you. But if you just say that, hey, if I, if this is safe and there's no problem with it and we just replacing glutamate back in your system, they will not approve the product. Because what does it do?

Well, there's so many reactions. Right. Well, you cannot, you cannot market this product as all these reactions. What are you gonna market as? Right. So they are looking at what are you gonna market as? And if that's what you're gonna market, that's all you can say it. So let's see if you say that glutamate is gonna be good for removing alcohol from your body. Okay, that's all you're gonna say. Shumist study, and that's all you're gonna measure that part.

But yet, that is not even the main focus. The main focus is so much more. And so we have lost focus on how we get the drug approval process. And quite honestly, I think we need to figure this thing out to see what else can we do to have better medicine for mankind to flourish instead of solving the problems over, solving the problems for our body. That's I'm going to. Yeah, I agree with that.

So Dr. Patel, what else does my audience need to know about glutathione and where it's the next five years for Dr. Patel in a perfect world? What's gonna come out of your lab in the next five years? Well, the next five years, my patients are not gonna see a whole lot of drugs because if it comes out, it'll become out to the doctor's offices first. Okay. You know, it's like just keep in mind because it should be 15 years of release glutathione. Wow. I'd just go back into 2007.

What, just because of the research? What were research? I'd never release any product until I know for fact that I'm gonna give it to myself, my dad, my family, everybody else, and they're healthy as hell. And then I make sure that I have some studies to back it up and I do my own research to make sure that what I'm creating is actually working for my patients. So, but if you're working with you or doctors, offices that I work with, you'll have early access to those products.

These are my small fragments. I'm looking at some skin peptides right now. I'm looking at NAD as a peptide right now. So, I'm looking at a few products that are earth shattering. Because I have very few years left in my research route, for me, 10, 20 years left. And I wanna make sure that I make a major impact. Glutathide itself is a, it's an once in a lifetime impact for me. But if I have one more product above beyond that, will be for me.

And right now, you've got NAD and development and a few peptides. And a few peptides. It's amazing to hear. Well, I always end every podcast by asking my guests the same question. So, there's no right or wrong answer to this question, but what does it mean to you to be an ultimate human? Oh, wow. Okay. Okay. I'm gonna give you a story because, I mean, I just lost my father two weeks ago. Sorry. So, he was, he was 89, walking six miles per day, enjoying life, travels the world.

He just fell down and just caught. Am I? No, he fell down. Oh, so. Blunt force trauma on his head. And he was, he was, he was, he was, he was, he was, he was, a blunt force trauma on his head, hemorrhaging. And the cause of death, they say, was brain hemorrhaging. Because he was stable, conscious, everything was fine. We talked about Dr. Joseph Maroon. You know, talk to him. He just, he saw the CTs where everything was fine.

So, to be an ultimate human, what I see, I look at my dad, I said, I wish I can literally do everything I want to do, walk, travel, enjoy life, everything. And when my time is up, just pick me up. Pick me up. And hopefully my time is not until 120 and 150, hopefully. But, but when my time is up, just pick me up. Do not make me suffer. Right. And so, what everything that I do today is making sure that I give my body the chance to literally self heal itself.

I want it to completely be free of medicine, free of, free of every single thing that is not natural to humans. Yeah. If I can do that part, if the body is just like perpetually healing itself and it goes all the time, that'll be ultimate for me. Fantastic. What a great answer. What an absolutely amazing answer. And I, I happen to feel softly really agree with you. I feel like modern medicine is coming full circle. We're getting back to the basics.

We're starting to realize that we should believe more in what God gave us than what man makes us. And when we enhance the things that nature provided us from the very beginning, we start to release. We start to reach things like, you know, ending disease and pathology and really living an optimal life. So, I feel softly really agree with you. I can't think enough of coming on the podcast today. I think everybody is going out to buy glue to thigh on right now.

I, I, I literally, you know, it's funny. I actually use your product and I actually sprayed it on my forearm before I came in here, especially for those of you that have the MTHFR gene mutation or other gene mutations that interrupt glue to thigh on, you know, pathways and cellular waste elimination. He is a phenomenal human being as an incredible product. I will put it in the show notes below. How can people find out more about you? How can people find you? Get your book.

The book is everywhere. I think it's, you know, most of it is audible, has a kindle, is I'm a paper bug book kind of guy. So I have a paper books. So it has on my website as well. My website is aurowellness.com. Aurowellness. AUROwellness.com. Fordslash Gary. Ah, Fordslash Gary, I got my own. You're going to get your own landing case. Aurowellness. AUR. Oh, wellness.com, RO wellness.com. So we'll put that in the show notes too. I'll put a link to your book in there. Do you have an Instagram?

I do have an Instagram. It's at Aurowellness. Same thing. Yes, beautiful. So we'll drive. And at AuroSkin Care as well, we have two of course. You know, people are, when they feel good from inside, they don't look beautiful too, right? So we want to help them. We really do. Great. Thank you for coming on the podcast stage. podcast day. This was amazing, my friend. Thank you. Appreciate it. And that's just science.