The Startup Ideas Podcast - podcast cover

The Startup Ideas Podcast

Greg Isenbergwww.gregisenberg.com
Get your creative juices flowing with The Startup Ideas Podcast. Published twice a week, we bring you free startup ideas to inspire your next venture. Hosted by Greg Isenberg, CEO of Late Checkout and former advisor to Reddit and TikTok. Subscribe so you don't miss out. For more startup ideas, we created a database of 30+ startup ideas you can take at https://gregisenberg.com/30startupideas
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Episodes

You are using Claude Fable 5 wrong

Get my Fable 5 prompt pack: https://startup-ideas-pod.link/fable5-prompt-pack In this episode I break down how to get the most out of Fable 5, the most powerful model I've ever used. I move past the benchmarks and go straight into tactical use cases, copy-and-paste prompts, and startup ideas you can build today. I walk through tournaments for copy and landing pages, an interview-before-build workflow that hunts for product-market fit, and ways to point Fable at contracts, churn data, and years o...

Jun 11, 202633 min

What are Agentic Loops?

S/o Coderabbit for sponsoring today’s vid: https://startup-ideas-pod.link/code-rabbit On this episode I sit down with Professor Ras Mic to break down agentic loops. We define what a loop is, explain why well-known builders like Boris and Peter swear by them, and stay honest about who they truly serve. Mic argues that human-in-the-loop remains the strongest setup today, and he walks through the one loop he runs every day for code review using Cursor, GitHub, and Greptile. By the end you will know...

Jun 09, 202623 min

Become AI Native in less than 60 mins

Become an AI Native Organization: https://startup-ideas-pod.link/ai-native-org In this episode I sit down with Theo to unpack what becoming AI native truly means. We define an AI native org as people managing agents, agents reading and writing to the company, and the company growing smarter over time. Theo opens his actual workflows, walking through a working prototype, an auto-generated client proposal microsite, and a live usability test that synthesizes feedback into a V2 in one session. We c...

Jun 08, 202657 min

Hermes Agent App Clearly Explained (and how to use it)

In this episode, I sit down with Alex Finn for a full, screen-shared walkthrough of Hermes Desktop, the new desktop home for the Hermes AI agent. I open with a clear challenge: by the end, sell me on installing Hermes Desktop, show me real ways to make money and stay productive, and explain his move from OpenClaw. Alex tours every major surface — sessions, profiles, artifacts, skills, cron jobs, and sub-agents — and shares money-saving tactics at each step. We close on the idea that matters most...

Jun 06, 202644 min

Codex Sites Clearly Explained (and how to use it)

In this solo episode I walk through Codex Sites end to end, building a real internal tool live so you can copy the exact workflow. I open by comparing Codex Sites with one-prompt tools like Replit and Lovable, then construct a Startup Ideas OS board in six prompts. Along the way I cover memory and persistent storage, safe actions, Codex skills, save-gates, and proving the loop so the app updates autonomously. The core promise: by the end you know how to ship a Codex Site that an agent keeps oper...

Jun 04, 202625 min

The Next $100B Market: Selling To AI Agents

This episode explores the transformative shift from a human-first internet to an agent-first one, where AI agents become primary customers. It details the agent buying journey, identifying their unique needs like identity, tools, wallets, and inboxes, and provides concrete examples of agent-native infrastructure. The discussion also covers how startups must adapt their websites and strategies, offering rapid-fire ideas for the emerging agentic economy.

Jun 02, 202614 min

Google's Biggest AI Announcements (I Was There)

Live from Google I/O, I sit down with Logan Kilpatrick from the Google DeepMind team to unpack everything Google just announced and what it means for founders, developers, and anyone trying to build with AI right now. We dig into Gemini 3.5 Flash, the new Gemini Omni world model, the expanded Antigravity ecosystem, managed agents in the Gemini API, and the native Android app builder inside AI Studio. Logan breaks down how distillation is pushing Pro-level intelligence into Flash, where the bigge...

May 22, 202626 min

9 Huge Startup Opportunities in the AI Boom

I sit down with my friend Jonathan Courtney, a.k.a. Jicecream, to dig into the 9 biggest startup opportunities I see right now across B2C, AI, mobile, and IRL. We each pick ideas, trade reactions, and pressure-test them live. The conversation ranges from agent-first "action apps" to elder tech, third spaces, hobby retreats, pet health, AI-native media, and the case for selling AI "junior employees" to small businesses. Listeners walk away with a concrete map of where to build in 2026, plus the f...

May 18, 20261 hr 8 min

Andrew Wilkinson: AI Agents run my business and life

If you want more workflows and tactics to build a business with AI, check out this free workshop: https://www.ideabrowser.com/workshop I sit down with Andrew Wilkinson and we go deep on how he's restructured his work, his health, and his family office around AI agents. Andrew walks me through Deep Personality (an app he vibe-coded after running psychological screens on himself and his girlfriend), the autonomous SaaS business he runs through agent harnesses like Harbor, and the vector-database s...

May 14, 202647 min

The $1M+ Solo AI Agent Business (Full Course)

Nick agreed to personally set up your Orgo in a 15 min call: https://startup-ideas-pod.link/orgo_ai I sit down with Nick from Orgo to break down exactly how to run a one-person AI agent business that can realistically clear a few million dollars a year. Nick walks through the offer, the verticals worth chasing, the full software stack, and the live setup of an agent that manages other agents. We focus on tactics over theory, with specific tools, pricing, and the playbook for landing customers as...

May 12, 202648 min

7 tiny AI agent ideas I built with Genspark Claw

Get started building your tiny AI Agent business with Genspark Claw: https://www.genspark.ai/?utm_source=po&utm_campaign=GregIsenberg In this solo episode, I share seven tiny, cash-flowing startup ideas you can build with AI in just a few prompts. I walk through how to use Genspark Claw, Genspark's new in-the-cloud agent product running Sonnet 4.6, and demonstrate two ideas I have already built (a dead domain flipper and a local restaurant liquidation broker), build a third idea live on came...

May 12, 202630 min

My AI Design Workflow That Doesn't Ship Slop

I sit down with Meng To for his second appearance on the pod to dig into design md, Google's newly open-sourced format for capturing the soul of a design and porting it across every medium and tool. Meng walks me through a live demo of how he uses design md alongside skills, HTML references, and tools like Aura, New Form, Codex, and OpenClaw to ship landing pages, motion design, slides, and mobile mocks that actually feel custom. We get into the design drift problem with one-shot prompts, why ta...

May 12, 202651 min

Hire a team of AI Agents

I'm joined again by Imran Muthuvappa to walk through how to build your own AI Chief of Staff using a tool called Nebula. Imran shows me how to spin up specialized agents that handle the work a real chief of staff would do — surfacing team blockers, tracking project status, holding people accountable to offsite vision goals, running daily agenda briefings, and prospecting ICP leads. We also get into mini apps, model selection for cost efficiency, and why personal software is becoming a real categ...

May 08, 202641 min

How to win with AI Agents in 2026

Limited BONUS: First 1,000 builders get $1,000. Claim yours while supplies lasts.: https://startup-ideas-pod.link/hyperagent I sit down with Howie Liu, co-founder and CEO of Airtable, to talk about the agent economy and the launch of HyperAgent. We walk through Sequoia's charts on AI agent deployment, the economics of token-based work versus human labor, and why frontier agents have crossed a threshold that changes how companies get built. Howie then does a live show-and-tell of HyperAgent, incl...

Apr 29, 20261 hr 27 min

Codex clearly explained (and how to use it)

I sit down with Riley Brown to get a hands-on tour of OpenAI's Codex, which he argues is the most powerful single interface for using AI agents today. Riley walks me through how Codex unifies vibe coding, knowledge work, browser use, computer use, and automations into one app, all running on GPT 5.5. I come in as a complete Codex skeptic who has spent most of my time in Claude Code, and Riley shows me skills, plugins, projects, Remotion, Chronicle, and the in-app browser to make his case. By the...

Apr 27, 20261 hr 26 min

ChatGPT Images 2.0 Is Here. I Tested Everything.

In this solo episode, I walk through ChatGPT Images 2.0 and show exactly how to use it to build creative assets that move a business forward, from brand visual directions to UI mockups to apparel mockups and editorial illustrations. I share the AI tool that surprised me this week (Noscroll), hand over a startup idea I want someone to steal (a learn-to-draw app with AI feedback on every sketch), and give you a five-step framework for finding and building a vertical AI business. I end with a Ralph...

Apr 22, 202632 min

Hermes Agent clearly explained (and how to use it)

I sit down with Imran Muthuvappa to get a hands-on walkthrough of Hermes Agent, a personal AI agent that ships with built-in memory, 40+ tools, and pre-installed skills out of the box. Imran walks me through why he migrated from OpenClaw, how to install Hermes on a Mac or even an Android phone via Termux, and how he cut his token spend by roughly 90% using OpenRouter. We get into agent design (one agent vs. multiple), connecting Hermes to Telegram and Obsidian, and the kinds of prompts that turn...

Apr 20, 202637 min

Claude Design blew my mind

I go live and get my hands dirty with Claude Design, Anthropic's new design tool in research preview. Across roughly an hour, I run a real workflow end-to-end: pulling a product idea from Idea Browser, generating wireframes, iterating into visual designs, building a pitch deck, and attempting a 30-second video ad. I share my first reactions in real time and take feedback from the chat. By the end, I land on a clear verdict — best-in-class for wireframes and visuals, weaker for video — and give y...

Apr 18, 20261 hr

Seedance 2.0: Make 100 AI Ads in 33 mins

In this episode I sit down with my friend Sirio, one of the most creative AI minds I know, to break down Seedance V2. Sirio walks us through the exact use cases, prompts, and tactics he's using to build on top of this model inside his platform Enhancor, covering multi-input generation, virtual try-ons, ad translation, AI influencers with lip sync, video extension, and 3D product template replacement. I wanted this to go beyond the "look how cool this is" tutorials and focus on how creators and f...

Apr 17, 202633 min

My Claude Code marketing stack (It just works)

I sit down with Amir, who's back on the pod, and we walk through the full stack of taking a business idea from zero to a validated, A/B-tested landing page in a single session. I use Idea Browser's new MCP integration with Claude Code to pull project context, generate a lead magnet concept, design a landing page in Paper, and then wire up analytics and live experiments through HumbleLytics — all without writing a single line of front-end code manually. We cover the tools, the workflow, and why t...

Apr 13, 202635 min

Building AI Agents (Clearly Explained)

I sit down with Ras Mic to break down how AI agents actually work and why most people are using them wrong. Ras Mic explains the mechanics of context windows, makes the case that agent md files are largely unnecessary, and shares his step-by-step methodology for building custom skills that make agents dramatically more productive. Whether you're coding with Claude Code or automating workflows with OpenClaw, this episode gives you the foundational knowledge to stop wasting tokens and start gettin...

Apr 08, 202635 min

How I use Lindy AI to run my life

I sit down with Flo, founder of Lindy, to get a live demo of their new product, Lindy Assistant, an AI executive assistant that lives in iMessage and works proactively across email, calendar, Slack, Notion, and 100-plus other tools. Flo walks me through a real day of his own Lindy usage, showing how it drafts email replies, prepares meeting briefs, updates CRMs, and handles calendar changes without being asked. We compare Lindy to OpenClaw and Claude's ecosystem, talk pricing, edge-case power us...

Apr 06, 202631 min

23 AI Trends keeping me up at night

I go solo on this episode to walk through the full list of AI trends and opportunities keeping me up at night — literally. From the one-hour company stack to ambient businesses, vertical AI, the agent economy, and the real security threats I see coming, I cover what I believe is the most asymmetric window in startup history. I share the frameworks I use to think about what to build, what to avoid, and why acting now matters more than waiting for things to settle down. Timestamps 00:10 – Intro 01...

Apr 01, 202632 min

Making $$ with AI Marketing

This episode argues that while AI commoditizes code, distribution is the new essential moat for startups. It outlines seven actionable strategies for builders to acquire customers, including using MCP servers for sales, programmatic SEO, and free tools as marketing. The discussion also covers optimizing for AI answer engines, creating viral shareable outputs, acquiring niche newsletters, and leveraging AI for content repurposing, empowering founders to scale their businesses effectively.

Mar 30, 202627 min

I Built an AI Agent Company (From Scratch)

I sit down with Dotta, the pseudonymous co-founder of Paperclip, the open-source agent orchestrator that exploded to 30,000 GitHub stars in under three weeks. We walk through a live demo where I pick a startup idea from my idea browser and we spin up a full AI-agent company in real time — hiring a CEO, founding engineer, QA agent, video editor, and content strategist inside Paperclip. Dotta shares practical tips on agent configuration, memory systems, skill installation, and the "Memento Man" me...

Mar 26, 202647 min

What is Firecrawl?

I break down Firecrawl and it solves AI’s biggest blind spot, access to clean web data. I walk through the full AI agent stack every builder needs, explain why this is the "AWS moment" for web data, and share a dozen startup ideas you can build this week using Firecrawl for scraping, enrichment, and automation. Whether you want to launch a niche SaaS, a lead gen service, or a data-as-a-service business, this episode gives you the frameworks and the specifics to get started. Shoutout Firecrawl - ...

Mar 24, 202627 min

My OpenClaw setup that finally works (Complete Walkthrough)

I sit down with Moritz Kremb, an OpenClaw power user and agency builder based in Berlin, to break down how to actually make OpenClaw useful. Moritz walks through a 10-step optimization guide covering everything from troubleshooting and memory management to model selection and security basics. He then demos two real systems he built with OpenClaw: a full short-form video content pipeline and a conversational CRM. This episode is for anyone who tried OpenClaw, hit a wall, and wants a clear path to...

Mar 19, 20261 hr 5 min

AI Agents Full Course 59 Minutes (for beginners)

Greg Isenberg and Remy Gaskell demystify AI agents, explaining how they differ from chat models by focusing on goal-to-result execution through an "observe, think, act" loop. The discussion dives into practical applications, showing how to create self-improving agents using markdown-based context files (agents.md, memory.md), integrate everyday tools via MCP, and develop reusable "skills" (SOPs for AI) to automate complex tasks and entire departmental workflows. By the end, listeners learn to drive any agent platform and build an AI operating system.

Mar 17, 202659 min

Autoresearch clearly explained (why it matters)

I break down Andrej Karpathy's new open-source project, Autoresearch: what it is, how it works, and why some of the smartest people in tech are losing their minds over it. I walk through 10 concrete business ideas you can build on top of Autoresearch loops, from niche agent-in-a-box products to always-on A/B testing agencies. I also cover Karpathy's companion launch, Agent Hub, share community reactions, and show you step by step how to get started using Claude Code and a Colab GPU. I'm hosting ...

Mar 11, 202624 min

I let OpenClaw run my organic marketing (while I sleep)

I sit down with Oliver Henry, a full-time employee who is generating hundreds of dollars in monthly recurring revenue from mobile apps he barely touches, thanks to an AI marketing agent he built on OpenClaw called Larry. We walk through how Larry autonomously creates TikTok slideshow content, reads analytics, iterates on hooks and CTAs, and feeds performance data back into the content loop. Oliver also shares how he packaged the entire system as a free, downloadable skill on Larry Brain so anyon...

Mar 09, 202643 min
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