In today’s episode, the final episode of The Single-Cell World , Cátia makes a surprising confession. Before speaking with today’s guest, she always assumed that the plastic consumables in single-cell and spatial transcriptomics kits were made by the same companies that developed and commercialized the technology. But, as it turns out, that’s not the case. In fact, many of these critical consumables are produced by specialized manufacturers—like Edge Precision Manufacturing . To know more about ...
Jan 21, 2025•1 hr 8 min
10x Genomics is world-class for single cell sequencing technology. As the company continues to innovate and launch exciting new products, it can be challenging to stay up to date on the portfolio and technology, even for us experts. In this episode, I talk to Michael Schnall-Levin , Chief Technology Officer and Founding Scientist at 10x Genomics. He shares everything you need to know about their Chromium single cell sequencing solutions. We cover Chromium instruments, new GEM-X assays, pricing u...
Dec 12, 2024•47 min•Season 5Ep. 59
TileDB software is transforming how scientists manage and analyze data. This includes single-cell omics data. In this episode, Tommy Tang and I talk to Aaron Wolen , Principal Software Engineer at TileDB, to explore the unique capabilities of TileDB-SOMA . Aaron breaks down how this specific software addresses the complexities of single-cell sequencing data, offering robust data management, streamlined workflows, and scalable analysis tools tailored to any needs. We discuss its core features, re...
Dec 05, 2024•33 min
Hosted by : Catia Moutinho & Tommy Tang Guest: Jonathan Alles , Founder of EVO BYTE Digital Biology In this episode, Jonathan tells us how EVO BYTE ’s EVO Data platform is revolutionizing data management for research labs, with a focus on single-cell research. Our conversation covers EVO BYTE’s unique solutions, customization capabilities, practical applications, and the role of automation in bioinformatics workflows. Jonathan also shares his insights on the future of computational biology a...
Nov 14, 2024•51 min
In this podcast episode, I talk with Francesca Giannese about an exciting new method for studying chromatin at the single-cell level called scGET-seq . Unlike previous methods such as scATAC-seq, which only allow us to study open chromatin, scGET-seq provides insights into both open and closed chromatin. This breakthrough can lead to a deeper understanding of how chromatin structure impacts gene regulation in individual cells. Tune in to learn more about how scGET-seq works and its potential app...
Oct 17, 2024•39 min
This episode features the audio from an interview where Divya Dhasman from GenoWrite speaks with Catia Moutinho . They discuss the evolution of The Single-Cell World and explore the role of technology in advancing genomics. Special thanks to Paul Naphtali for making this interview possible. Catch the full interview here . Thanks to you for listen. Hit the ❤️ if you liked it and share it with your colleagues. Get full access to Single-Cell World at thesinglecellworld.substack.com/subscribe...
Sep 12, 2024•16 min
In this episode, I speak with Shuwen Chen , a product manager at Takara Bio , who provides an in-depth look at the various solutions they offer for single-cell research projects. We discuss the Smart-Seq kits, explore their single-cell platforms, and dive into the latest Shasta kits for RNA and DNA. Tune in to find out if these innovative solutions can enhance your research projects. Useful links * Arc-well: a new method for single-cell DNA-seq analysis of formalin-fixed paraffin-embedded sample...
Aug 15, 2024•38 min
In this episode, I talk with Adrian Zambrano , Customer Success Manager at CYTENA . We’ll discuss instruments that can be used in single-cell projects, including upstream tools like single cell dispensation instruments and downstream solutions like automatic bead clean-up. Discover innovative solutions from CYTENA that could enhance your research projects. Tune in to learn how these tools can make our lab work easier and more efficient. Useful links * Resources Cytena * Support this podcast. 👉�...
Aug 01, 2024•39 min
BD Biosciences , known for their cytometers, also offers impressive single-cell sequencing solutions. Today’s guest is Hasi Patel , Senior Single Cell Solutions Architect, who tells me everything about this technology during this episode. Hasi starts explaining how BD's latest high-throughput single-cell platform works, as well as all the multiomics approaches that can be done with their innovative solutions. In all of them, sample multiplexing is possible, enhancing its versatility. Hasi also s...
Jul 18, 2024•50 min
In this episode, Irene González , the International Key Account Manager at Arrays For Cell Nanodevices, SL ( A4cell ), discusses their microdevices known as SPAchips . She explains how these devices allow us to directly measure various characteristics in living cells, such as reactive oxygen species (ROS), calcium and pH levels. A4Cell email: info@a4cell.com Support our podcast: pay us a Ko-fi Get full access to Single-Cell World at thesinglecellworld.substack.com/subscribe...
Jun 27, 2024•24 min
Join me, Cátia Moutinho, as I break down the basics of spatial transcriptomics legal battles ⚖️ between companies in this field. I'll share my opinions 💭, propose solutions 🛠️, and raise open questions ❓ that might have you thinking. This is a message for judges, companies teams and researchers. 😉 Tune in now! 🎧 The Single-Cell World Blog , Newsletter . Pay us a Kofi Get full access to Single-Cell World at thesinglecellworld.substack.com/subscribe...
Jun 13, 2024•30 min
In this episode, Ritika Kulshreshtha , Singleron Account Manager, tells me everything about their different kits for single cell experiments. For example, a kit to study DNA and RNA in parallel, another to study glycosylation, mRNA from yeast, or nascent RNA. So, if you are interested in doing novel single cell experiments, listen to this episode now! Useful links: Singleron Boot Camp Support our Podcast (2$ per month) Get full access to Single-Cell World at thesinglecellworld.substack.com/subsc...
May 23, 2024•43 min
Hi there 👋 The topic of this episode is VASA-seq, a single-cell transcriptomics method that we can use to study coding and non-coding RNA. Listen now to my conversation with Fredrik Salmén , the first author of the paper where VASA-seq is described. He gives me an amazing explanation about this method, besides his opinion on other topics related to single-cell and spatial experiments. You will not want to skip this one! Other useful links: * Pay us a Ko-fi * SORT-seq * Atrandi Biosciences * Sin...
May 09, 2024•39 min
In this podcast episode, I have the pleasure of talking with Kevin Travers , the Senior Vice President for R&D at LevitasBio . Kevin tells me everything about their gentle and label-free technology that can be used during sample preparation for any single cell sequencing experiments, but also for other downstream applications. 🎧Tune in now and learn how levitation technology can make your experiments better.✨ Useful Links: * Levitation Technology for Single Cell Genomics * The LeviCell Syst...
Apr 25, 2024•42 min
Join us on this podcast episode as I explore the fascinating world of single-cell RNA sequencing (scRNA-seq) data normalization with Amartya Singh, a post-doctoral researcher at Reuters. Discover the limitations of the standard methods used in scRNA-seq data normalization and how Amartya's innovative solution is changing the game. Hear firsthand about his journey of inspiration and the ideas that led to the development of this groundbreaking approach. Don't miss out on this insightful discussion...
Apr 11, 2024•4 min
In this insightful podcast interview with Kieren Patel, the Chief Business Officer at Resolve Biosciences, we delve into the world of Molecular Cartography technology. Kieren provides details about this innovative platform, underscoring its remarkable capabilities in facilitating high molecular resolution pathology. Additionally, Kieren sheds light on forthcoming solutions set to be commercialized later this year, with a particular emphasis on their commitment to multiomics and customized approa...
Mar 28, 2024•34 min
In this podcast episode, I had the privilege of talking with Melanie Masuda, the Director of Market Development at Scale Biosciences. Melanie told me all about Scale Biosciences' cutting-edge technology and gave me a full overview of all of their different kits. Listen now and understand how the single-cell (sc) sequencing DNA methylation, the scRNAseq, and the CRISPR enrichment kits work. Maybe this is the solution for your research project! Useful Links: Melanie Masuda LinkedIn Scale Bioscienc...
Mar 14, 2024•33 min
In this insightful podcast episode, I have the privilege of interviewing Simone Picelli, the Head of the Single-Cell Genomics Platform at the Institute of Ophthalmology Basel. As we talked, we got into the specifics of single-cell RNA sequencing (scRNA-seq) full-length methods from the SMART-seq family. Simone shared valuable insights into various methods within, including SMART-seq, SMART-seq 2, SMART-seq 3, FLASH-seq, FLASH-seq low-amplification, and FLASH-seq with UMI. We explored the unique ...
Feb 29, 2024•1 hr
The Single-Cell World Podcast is now available in video as well, but just on Apple Podcast and in our new YouTube channel 😉 Episode 14: Single-Cell Methods, an overview, needed an update since there is a fourth method that is being used to individualize cells when using single-cell sequencing technology. Join me and listen to it, as well as other updates concerning the methods that are at the core of the single-cell sequencing technology. Here I leave you a gift, related with this episode. Than...
Jan 11, 2024•7 min
Hi there! Today is Part 2 of the review of single-cell-related products launched in 2023. I hope I don't miss any. If I do, send me a message telling me about it. 😉 Here are some useful links: Exploring Single-Cell Sequencing online course Companies that I talk during this episode (part 2): Scale Biosciences Scipio Bioscience Singleron Biotechnologies Takara Bio 10X Genomics Free Resources Sponsorship Pay me a Ko-Fi Thanks for listening! Cheers, Cátia Get full access to Single-Cell World at the...
Dec 11, 2023•14 min
Hi there! Today I review single-cell-related products launched in 2023. They are a lot! I hope I don't miss any. If I do, send me a message telling me about it. 😉 Here are some useful links: Join the Single-Cell World Newsletter Companies that I talk during this episode (part 1): BD Biosciences Ep. 18: Samples Multiplexing BioScryb Genomics Fluent BioSciences Episode 31: Podcast Fluent BioSciences Honeycomb Biotechnologies Episode 19: Podcast Honeycomb Biotechnologies Mission Bio Episode 16: Po...
Dec 04, 2023•18 min
Hello there! The Spatial and Single-Cell Analysis Playbook was released last week. Front Line Genomics produced it. I was honored to be invited to take part in it. In this episode, you can hear the questions that were asked (AI voice here) and my responses during this fantastic interview. I hope you like it! Useful Links Free Resources The Single-Cell World website Sponsorship Pay me a Ko-Fi Thanks for listening. Cheers, Cátia Get full access to Single-Cell World at thesinglecellworld.substack.c...
Nov 20, 2023•13 min
Hi there! Would you like to know what quality control steps I think are essential before a spatial transcriptomics experiment? In my experience, these control steps can save you a lot of headaches. Listen now, and tell me if you agree. Useful Links The Single-Cell World website Sponsorship Pay me a Ko-Fi Thanks for listening. Cheers, Cátia Get full access to Single-Cell World at thesinglecellworld.substack.com/subscribe...
Nov 13, 2023•16 min
Discover the marvels of MERSCOPE®, a revolutionary platform that's reshaping the world of single-cell spatial transcriptomics. Think of it as Google Earth for genes; it allows us to directly map and quantify the spatial distribution of hundreds to tens of thousands of RNA species in individual cells. Dr. Jiang He, Vizgen’s Scientific Co-founder and Senior Director of Scientific Affairs explains everything about the MERSCOPE® technology! Listen now to learn more about single-cell spatial technolo...
Nov 06, 2023•31 min
Hi! Would you like to get a general idea about the sample preparation standard protocols for spatial transcriptomics experiments? Listen now 😉. Useful links: Youtube Videos Frozen Tissues Preparation FFPE Tissues Preparation How to Cut Your Frozen Tissue Sample To Get Beautiful Sections? OCT Blocks Prep Support this podcast Ko-fi Sponsors Thank you so much for listening. Cheers, Cátia Get full access to Single-Cell World at thesinglecellworld.substack.com/subscribe...
Oct 30, 2023•15 min
Welcome to this episode, in which I have a fascinating conversation with Charles Roco, the founder and CTO of Parse Biosciences. In our conversation, Charlie talks about Evercode single-cell technology. We look into the amazing flexibility of this technology, which allows us to go beyond the limits of gene expression analysis. Join us as we examine this intriguing high-throughput technology that 96-well plates allow for. Parse Biosciences useful links: Website Resources : application notes, whit...
Oct 23, 2023•44 min
Hi tere, Do you know that besides solid tissues, we can use other types of samples for Spatial Trancriptomics? Listen now to this episode podcast to know about all the sample types that can be used. Useful links: Support this podcast by buying me a coffee! Single-Cell World Website Thanks for listening! Have a lovely day, Cátia Get full access to Single-Cell World at thesinglecellworld.substack.com/subscribe...
Oct 16, 2023•13 min
In this episode, Dr. Elizabeth Tseng, associate director product manager at PacBio, explains everything about the MAS-Seq kit, a game-changer for producing long-read libraries. With the backing of single-cell industry giant 10X Genomics, the MAS-Seq kit promises to redefine the future of single-cell RNA seq assays. Whether you're a scientist or just curious about the future of single-cell research, this episode is your guide to the cutting-edge advancements in the field. Tune in to learn, explor...
Oct 09, 2023•23 min
Hi! This is our first live episode on Instagram: Spatial Trancriptomics Image-Based Methods🎙️ In this live, I talk about the different methods that are in the base of some of the Spatial Transcriptomics technology. Listen now! Usefull Links Support this podcast Join Our Newsletter New Website Thanks for listening! Cheers, Cátia Get full access to Single-Cell World at thesinglecellworld.substack.com/subscribe...
Oct 02, 2023•21 min
Hi there, In this episode, I talk with Kristina Fontanez, PhD, co-founder and Senior Vice president of Product Development at Fluent Biosciences. We talk about the groundbreaking PIPseq single cell technology. Step into the fascinating world of single-cell RNA sequencing as Kristina demystifies the revolutionary PIPseq method that is making waves in single-cell research. What makes PIPseq stand out? Tune in now! Fluent Biosciences useful links: Website Resources : application notes, whitepapers,...
Sep 25, 2023•29 min
