Send us a text We’re back this week with Kieran and Ashley to take another look at diabetes and sweet treats. Should current practice guidelines be taken with a grain of salt – or should I say – sugar? Listen to find out! New drugs have popped up on the market for diabetes management, necessitating an update to practice ... The post Testing and Treatment in Diabetes – Taken with a Grain of Sugar! appeared first on Healthy Debate ....
Oct 28, 2016•31 min
Send us a text A recurring question: in the management of BP, how low should we go? This week, Paxton and Kieran discuss two studies that aim to refine the answer. The appropriate treatment target for systolic blood pressure in elderly patients with hypertension is uncertain, particularly for the frail elderly. Kieran leads the discussion on the SPRINT ... The post Aging gracefully – SPRINTing to the right blood pressure target! appeared first on Healthy Debate ....
Oct 21, 2016•35 min
Send us a text This week’s Rounds Table is all about studying studies, emphasizing the importance of understanding a body of evidence within the context of existing literature. A refreshing reminder that the “big picture” in medical research can be easy to lose sight of when keeping up to date with individual trials! Dr. Ashley Minuk, Family Physician ... The post The Bigger Picture: Industry Sponsored Research and Negative Trials appeared first on Healthy Debate ....
Oct 14, 2016•40 min
Send us a text Is October making you overtired and moody? Tune in this week as Dr. Paxton Bach, resident in General Internal Medicine at UBC, and Kieran discuss two tantalizing studies! The SAVE Clinical Trial is the largest ever to study the effect of CPAP on prevention of cardiovascular outcomes and death in patients with obstructive sleep ... The post Moody & unSAVEd – CPAP for Prevention of Cardiovascular Endpoints in OSA and SSRI Treatment of Depression in Heart Failure appeared first o...
Oct 07, 2016•29 min
Send us a text We’re back and better than ever with a NEW host! This season, Kieran Quinn takes the reigns and is excited to bring you the latest and greatest in the world of emerging clinical evidence. Along outgoing host Amol Verma, the two hosts discuss two studies: Just how dangerous are opioids in the treatment of chronic pain ... The post REPLAY – Drugs on the Brain: Opining on Opioid-Induced Death and Ticagrelor for TIA or Stroke appeared first on Healthy Debate ....
Sep 30, 2016•32 min
Send us a text Bugs, drugs, and optimal duration for antibiotic therapy? New frontiers in HIV treatment? Listen this week as Kieran and Jay Spiegel, a resident in General Internal Medicine in Toronto, discuss two studies: It’s hard to remember what the right drug is to treat a certain bug, let alone the correct duration of therapy. Further, ... The post Bugs & Drugs – Duration of Antibiotic Therapy in Community-Acquired Pneumonia and Early Antiretroviral Treatment for HIV appeared first on H...
Sep 23, 2016•39 min
Send us a text This week Kieran and Dr. Fraser Pollard, a Family Physician in Trenton, Ontario, discuss two studies: Using long acting beta agonists (LABAs) safely and appropriately in the management of asthma is widely debated, with evidence suggesting a potential risk of serious asthma-related events associated with the use of LABAs. But is the potential risk warranted? ... The post Dazed and Confused – Dexmedetomidine for the Prevention of Delirium and the Safety of LABAs in Asthma appeared f...
Sep 16, 2016•37 min
Send us a text We’re back and better than ever with a NEW host! This season, Kieran Quinn takes the reigns and is excited to bring you the latest and greatest in the world of emerging clinical evidence. Along outgoing host Amol Verma, the two hosts discuss two studies: Just how dangerous are opioids in the treatment of chronic pain ... The post Drugs on the Brain: Opining on Opioid-Induced Death and Ticagrelor for TIA or Stroke appeared first on Healthy Debate ....
Sep 10, 2016•32 min
Send us a text This week, Amol and Dr. Kieran Quinn, both general internal medicine residents at the University of Toronto, discuss two studies: Where do people die? What types of care do they utilize at the end of life? A retrospective cohort study of people who died with cancer in seven developed countries evaluated the number of deaths ... The post Summer Replay – Valued Care: End of Life Care and Early Trends from “Choosing Wisely” appeared first on Healthy Debate ....
Sep 02, 2016•33 min
Send us a text This week, Amol, resident in General Internal Medicine at University of Toronto, and Mike Fralick, chief medical resident at St. Michael’s Hospital in Toronto, talk about 2 blood pressure studies: A meta-analysis and systematic review found that more intensive blood pressure lowering was associated with improved cardiovascular outcomes and albuminuria. Amol discusses the trade-offs of ... The post Summer Replay – The SPRINT to lower blood pressure appeared first on Healthy Debate ...
Aug 26, 2016•33 min
Send us a text This week Amol and Nathan discuss two studies: A multi-centre, prospective study evaluated the physical and mental health status of caregivers for patients discharged from the intensive care unit (ICU). Using hospital data and self-administered questionnaires, the study found most caregivers of critically ill patients are at high risk for depression, anxiety and poor mental health. ... The post Summer Replay – Caregivers in the ICU and Symptoms in Smokers appeared first on Healthy...
Aug 19, 2016•35 min
Send us a text This week, Amol and Kieran discuss two studies: How can we prevent readmission? An observational study of 1000 general internal medicine patients from 12 United States academic medical centres found that 26.9% of readmissions were potentially preventable. Key factors associated with potential preventability included decision making in the emergency department, lack of information to outpatient ... The post Summer Replay – Pondering Preventability: Readmissions and Catheter-Associa...
Aug 12, 2016•34 min
Send us a text This week, Amol talks about new antithrombotic therapy guidelines and using low calorie diet for diabetes remission. The American College of Chest Physicians issued new antithrombotic guidelines for the treatment of venous thromboembolism in February 2016. Amol highlights five updates in the guidelines, and discusses the evidence behind each recommendation. Diabetes has long been described ... The post Summer Replay: New Antithrombotic Therapy Guidelines and Low Calorie Diet for D...
Aug 03, 2016•31 min
Send us a text This is our final episode of the year! We want to thank everyone who has hosted or contributed to the podcast, and of course you – our dear listeners – for tuning in every week. We will be re-playing some of our favourite past episodes, and bringing you brand new content in the fall. Good ... The post Season Finale: All ‘Good Stuff’ Must Come to an End appeared first on Healthy Debate ....
Jul 04, 2016•6 min
Send us a text This week, Amol and Rebecca discuss a recent study and an updated recommendation: A multi-centre, randomized control trial (the LEADER trial) examined the cardiovascular effect of liraglutide, a glucagon-like peptide-1 (GLP-1) analogue. Patients with type 2 diabetes and high cardiovascular risk were randomly assigned to receive either standard of care plus liraglutide or standard of ... The post Motherhood Statements: Cardiovascular Effect of Liraglutide and Syphilis Screening app...
Jun 24, 2016•30 min
Send us a text This week, Amol and Kieran discuss two studies: How can we prevent readmission? An observational study of 1000 general internal medicine patients from 12 United States academic medical centres found that 26.9% of readmissions were potentially preventable. Key factors associated with potential preventability included decision making in the emergency department, lack of information to outpatient ... The post Pondering Preventability: Readmissions and Catheter-Associated UTI appeared...
Jun 19, 2016•34 min
Send us a text This week Amol and Nathan discuss two studies: A multi-centre, prospective study evaluated the physical and mental health status of caregivers for patients discharged from the intensive care unit (ICU). Using hospital data and self-administered questionnaires, the study found most caregivers of critically ill patients are at high risk for depression, anxiety and poor mental health. ... The post Exam Prep: Caregivers in the ICU and Symptoms in Smokers appeared first on Healthy Deba...
Jun 11, 2016•35 min
Send us a text This week, Amol talks about new antithrombotic therapy guidelines and using low calorie diet for diabetes remission. The American College of Chest Physicians issued new antithrombotic guidelines for the treatment of venous thromboembolism in February 2016. Amol highlights five updates in the guidelines, and discusses the evidence behind each recommendation. Diabetes has long been described ... The post Spousal Input: New Antithrombotic Therapy Guidelines and Low Calorie Diet for D...
Jun 03, 2016•31 min
Send us a text This week, Amol and Janice, staff internist at Mount Sinai Hospital, discuss two studies: A randomized trial asked whether diluted apple juice works just as well as oral rehydration therapy in treating minimal dehydration in children with gastroenteritis. Children 6 to 60 months presenting to the emergency department were randomized to half-strength apple juice or ... The post New Territories: Apple Juice for Gastroenteritis in Children and Rheumatoid Arthritis Long Term Outcomes ...
May 27, 2016•31 min
Send us a text This week, Amol and Dr. Kieran Quinn, both general internal medicine residents at the University of Toronto, discuss two studies: Where do people die? What types of care do they utilize at the end of life? A retrospective cohort study of people who died with cancer in seven developed countries evaluated the number of deaths ... The post Valued Care: End of Life Care and Early Trends from “Choosing Wisely” appeared first on Healthy Debate ....
May 20, 2016•33 min
Send us a text This week, we are replaying one of our favourite past episodes. Originally aired on February 12, 2016, Amol, general internal medicine resident at the University of Toronto, and Fahad, staff internist at St. Michael’s hospital in Toronto, discuss 3 papers: Where do physicians die? What is the intensity of the care they receive at the ... The post Replay: How Physicians Die and Frozen Fecal Transplant for C. difficile appeared first on Healthy Debate ....
May 06, 2016•26 min
Send us a text What is the risk of adverse events after a transient ischemic attack (TIA)? While older studies tell us that the risk of stroke or acute coronary syndrome after a TIA is high in the first 3 months, does this hold true today? An international TIA Registry tried to answer this question by characterizing TIA and ... The post Talking TIAs: Physician Assisted Death in Canada and a Transient Ischemic Attack Registry appeared first on Healthy Debate ....
Apr 29, 2016•32 min
Send us a text This week, Amol and Nathan discuss two high profile papers: Authors from the Centres for Disease Control and Prevention (CDC) recently published a report concluding that there is a causal relationship between Zika virus infection and a syndrome of birth defects, notably microcephaly. Nathan and Amol review the evidence the authors presented for this causality, ... The post Blockbusters: Zika virus on birth defects and income on life expectancy appeared first on Healthy Debate ....
Apr 23, 2016•40 min
Send us a text This week, Amol and Reena, internist at St. Michael’s hospital in Toronto, discuss the HOPE-3 trial. HOPE-3 is a 2-by-2 double blind randomized placebo controlled trial, which found that statins were effective in preventing cardiovascular events in intermediate risk patients but anti-hypertensives were not. While candesartan and hydrochlorothiazide were not superior to placebo, rosuvastatin resulted ... The post A New HOPE: Statins and Anti-hypertensives in intermediate cardiovasc...
Apr 15, 2016•41 min
Send us a text This week, Amol and his co-host Reena, general internist at St. Michael’s Hospital in Toronto, discuss two recent papers on depression: What is the risk of cardiovascular outcomes in patients using antidepressants? A cohort study of patients age 20 to 64 found no evidence that selective serotonin reuptake inhibitors (SSRIs) are associated with increased cardiovascular ... The post Depression Session: Cardiovascular Outcomes with Antidepressants and Preventing Depression in Primary...
Apr 08, 2016•32 min
Send us a text This week, Amol and Nathan discuss breast cancer and colorectal cancer: Two randomized control trials compared the aromatase inhibitor anastrozole to tamoxifen as adjuvant hormone therapy for postmenopausal women with ductal carcinoma in situ. Both trials were double blind and multi-centred, with one trial (NSABP B-35) enrolling North American patients and the other (IBIS-II DCIS) ... The post Together Again: Aromatase Inhibitor for DCIS and New Colorectal Cancer Screening Recomme...
Apr 01, 2016•34 min
Send us a text This week, we debut a new format at the Rounds Table. Amol reviews articles published from the latest edition of four journals: Journal of the American Medical Association (JAMA), the Lancet, Annals of Internal Medicine and the New England Journal of Medicine (NEJM). Tune in to hear the latest medical findings, including mindfulness for back ... The post Headlines and Highlights: A Review of the Latest Edition of Four Journals appeared first on Healthy Debate ....
Mar 25, 2016•45 min
Send us a text This week, Amol discusses contrast induced nephropathy. At an overall reported incidence of 10%, contrast induced nephropathy leads to worse clinical outcomes and double the rate of mortality. A systematic review and meta-analysis on the effectiveness of prevention strategies found that there is no strong evidence for any intervention beyond volume expansion with saline. N-acetyl ... The post An Exercise in Contrasts: Contrast Induced Nephropathy and Exercise in Cancer appeared fi...
Mar 18, 2016•26 min
Send us a text This week we are replaying our first episode of the season. Originally aired on January 11, 2016, Amol, general internal medicine resident at the University of Toronto, talk about his 10 favourite papers of 2015. Rate us on iTunes! Follow us on Twitter @roundstable. The Papers 1. Teixobactin, a new antibiotic: http://www.nature.com/nature/journal/v517/n7535/full/nature14098.html 2. Modified Valsalva ... The post Replay: Amol’s 10 Favourite Papers of 2015 appeared first on Healthy ...
Mar 11, 2016•42 min
Send us a text This week, Amol, general internal medicine resident at University of Toronto, and Reena, general internist at St. Michael’s hospital in Toronto, discuss two recent papers: What exactly defines sepsis and how should sepsis be assessed? The Third International Consensus Definitions Task Force worked to define sepsis as “life-threatening organ dysfunction due to a dysregulated host ... The post Sepsis, Pepsis, and Happiness: New Sepsis Definition and Effect of Happiness on Mortality ...
Mar 04, 2016•33 min
