The Peter Attia Drive

Expert insight on health, performance, longevity, critical thinking, and pursuing excellence. Dr. Peter Attia (Stanford/Hopkins/NIH-trained MD) talks with leaders in their fields.

Last refreshed: June 22nd, 2026 at 1:11 PM

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Episodes

#397 ‒ Endometriosis and adenomyosis: diagnosis, fertility, reproductive aging, and emerging treatments | Renato Tomioka, M.D., Ph.D.

This episode features Dr. Renato Tomioka, an expert in reproductive medicine, who demystifies endometriosis and adenomyosis, conditions frequently overlooked despite their significant impact on women's health. He details the shift from surgical laparoscopy to advanced imaging for diagnosis, treatment decision-making balancing pain relief and fertility, and the critical role of age in reproductive outcomes. Dr. Tomioka also highlights common management mistakes and exciting developments in treating these chronic diseases.

Jun 22, 2026•1 hr 59 min•Ep. 397

#396 ‒ Breast cancer screening: understanding risk, deciding when to start and how often to screen, and choosing the right imaging strategy

This episode explores the critical issue of breast cancer mortality despite available screening, highlighting how under-screening and inconsistent guidelines contribute to late detection. Peter Attia provides a practical framework for personalized screening, detailing how to assess individual risk factors like genetics and breast density, choose appropriate imaging modalities (mammography, MRI, ultrasound), and determine optimal screening frequency and starting age. The discussion stresses that while population guidelines offer a baseline, a tailored approach significantly enhances early detection and successful treatment outcomes.

Jun 15, 2026•50 min•Ep. 396

#395 - Brain lipidology: understanding APOE, cholesterol homeostasis, Alzheimer's disease risk, and the effects of lipid-lowering therapies on brain health | Tom Dayspring, M.D.

Dr. Tom Dayspring discusses the intricate world of brain lipidology, explaining how the brain's cholesterol system is almost entirely separate from the peripheral system. The conversation delves into the pivotal role of ApoE in cholesterol homeostasis and its profound influence on Alzheimer's disease risk, connecting it to amyloid and tau pathology. They also analyze the evidence for statins, ezetimibe, omega-3 fatty acids, and novel CETP inhibitors on brain health, providing an essential framework for understanding these complex relationships.

Jun 08, 2026•1 hr 41 min•Ep. 395

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