The Life Scientific - podcast cover

The Life Scientific

BBC Radio 4www.bbc.co.uk

Professor Jim Al-Khalili talks to leading scientists about their life and work, finding out what inspires and motivates them and asking what their discoveries might do for us in the future

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Episodes

Clive Oppenheimer on the volcanic offerings of our angry earth

Clive Oppenheimer has, more than once, been threatened with guns (a Life Scientific first?). He's dodged and ducked lava bombs and he's risked instant death in scorching and explosive eruptions. He studies volcanoes; science that by necessity, requires his presence at the volcanic hotspots of the world. It was at the lip of a bubbling lava crater on one of the earth's most active volcanoes, Mount Erebus in Antarctica, that he met the film and documentary maker Werner Herzog. The two became frien...

Dec 11, 201829 min

Sky at Night presenter Maggie Aderin-Pocock

Maggie Aderin-Pocock has been fascinated by space since she was a young child. When she was six years old she caught the bug when she saw a picture of an astronaut on the front of a book in her primary school library. As a teenager she built her own telescope. After studying physics and mechanical engineering, Maggie worked in industrial research before returning to her first love, astronomy, when she managed the building of an instrument on a giant telescope in Chile. Now, she spends her time p...

Dec 04, 201828 min

Banning chemical weapons with Alastair Hay

Alastair Hay, now Emeritus Professor of Environmental Toxicology at the University of Leeds, is a chemist who’s had a dual career as an academic researcher and an outspoken activist and campaigner. The common theme has been the application of his knowledge to how chemicals affect our lives, in the workplace and during conflicts. Alastair Hay is best known for his work to rid the world of chemical weapons, a concern about this horrific form of warfare that goes back to the use of Agent Orange in ...

Nov 27, 201837 min

Formula One engineer Caroline Hargrove

How do you convince Formula One racing drivers that they are speeding round the race track at Le Mans when, in fact, they are sitting in a simulator in the McLaren offices in Woking? Apparently it’s all about getting the vibrations right. Racing drivers really do drive by the seat of their pants. They’re also highly attuned to the sound f the engine and instinctively associate different sounds with different speeds. When Caroline Hargrove started trying to build a driveable model of a Formula On...

Nov 20, 201828 min

Mike Stratton and cancer genes

When Michael Stratton was a young doctor he would diagnose cancer by studying tissue samples under a microscope. However, over the past 30 years he’s been advancing our understanding of this disease down at the level of the genes themselves, so that we are now able to read the DNA of a cancer. This had led to new diagnoses and treatments. Mike Stratton’s first foray into genetics culminated in the discovery of the BRCA 2, one of the main genes involved in hereditary breast cancer. Following this...

Nov 13, 201828 min

Detective of the mind Dr Suzanne O'Sullivan

Suzanne O'Sullivan has been described as “a detective of the mind”. She’s a neurologist who helps some patients with the strangest of symptoms, from so-called ‘Alice in Wonderland’ seizures to those suffering from temporary blindness or paralysis, and that turn out to originate in their subconscious minds. By the time these people get to see Dr Suzanne O’Sullivan they’ll often have been to many specialists, undergone a range of tests and given a variety of diagnoses. Suzanne’s an expert on epile...

Nov 06, 201828 min

Noel Fitzpatrick on becoming a supervet

For all his success as a Supervet on TV and as a pioneering orthopedic surgeon, Noel Fitzpatrick insists that his life has been full of failures. He didn’t enjoy studying for his specialist vet exams and spent ten years working as an actor before setting up his veterinary practice, Fitzpatrick Referrals. Determined to offer animals access to medical treatments and facilities that are more commonly reserved for humans, he has pioneered several new surgical procedures for small animals, specialisi...

Oct 30, 201828 min

Jacqueline McGlade on monitoring the environment from space

An ecologist who fell in love with computing, Jacqueline McGlade pioneered the use of satellites study the state of the global environment. Today thanks to programmes like Google Earth, we can see the surface of the earth in great detail. But when Jacqueline was a student, earth observation satellites were used for weather forecasting and not much else. Early in her career, she used satellite images to study fish populations, thinking it would be useful to know not only how many fish were in the...

Oct 23, 201828 min

Rachel Mills exploring the sea floor

Professor Rachel Mills is a marine geochemist who studies the sea floor and hydrothermal vents, where water erupts from the earth's crust at 360 degrees. The thick plumes emit many metals such as copper, gold, iron and rare earth minerals that are deposited on the sea bed. Rachel's career has taken her all over the world and 4km deep under the ocean in small submersibles. These journeys are exciting and terrifying as samples are taken to understand how the metals travel many thousands of miles. ...

Jun 19, 201828 min

Frank Close and particle physics

Frank Close is a theoretical particle physicist and a pioneer of popular writing about physics. His first book aimed at a non-specialist audience, The Cosmic Onion, was published 35 years ago. His latest, Half Life, is the story of physicist and spy, Bruno Pontecorvo. Frank has also had a distinguished research career studying the fundamental structure of matter. It was during his PhD in the late 60s that quarks were discovered. These are the fundamental entities we now know make up particles su...

Jun 12, 201842 min

Sheena Cruickshank on the wonders of the human immune system

Traditional descriptions of the human immune system bristle with military analogies. There are "lines of defence" against "enemy invaders"; "border guards" at "strategic points. And when barriers are breached, there's "a call to arms". That's before you mention Natural Killer Cells. But Professor of Immunology and Public Engagement at the University of Manchester, Sheena Cruickshank, tells Jim that as well as the war-like descriptions, our immune system is now being understood in terms of its ca...

Jun 05, 201828 min

John Taylor on being an inventor

John Crawshaw Taylor is a prolific inventor who specialises in designing and manufacturing thermostatic controls. His ingenious integrated control system is found in in one billion electric kettles worldwide, enabling kettles to switch off automatically when the water boils, stopping the element from boiling dry and preventing plastic kettles from catching fire under a worst case scenario. 600 million of his safety controls for the small electric motors have been sold to date, and are used mainl...

May 29, 201828 min

Cat Hobaiter on communication in apes

Dr Catherine Hobaiter studies how apes communicate with each other. Although she's based at the University of St Andrews in Scotland, she spends a lot of her time in the forests of Uganda, at the Budongo Research Centre. There, she's endlessly fascinated by the behaviour of great apes. Cat Hobaiter tells Jim al-Khalili about the difficulties of carrying out research on chimps in the wild. It can take years to win the trust of the apes. She says that her approach is to adopt the attitude of a moo...

May 22, 201828 min

Caroline Dean reveals the genetic secrets of flowering

As a girl, Caroline Dean would watch the cherry trees in her childhood garden unfurl their pink and white blossom and wonder how it was that they all flowered at exactly the same time. She tells Jim Al-Khalili that the flowering synchronicity she observed was to spark a life-long fascination with the timing mechanisms of plant reproduction, in particular with a process called vernalisation - how plants respond to extreme cold. Professor Dame Caroline Dean of the John Innes Centre in Norwich has ...

May 15, 201828 min

Carlo Rovelli on why time is not what it seems

Carlo Rovelli first became interested in the nature of time when he took LSD as a young man. Later he became curious about the world of the almost absurdly small, where time has no meaning and space is grainy. He took seven years to complete his undergraduate degree, having spent a lot of time protesting against the political establishment, falling in love and travelling. An extended hippy trip across north America was, he says, perhaps the most useful time of his life. All this rebelling taught...

May 08, 201828 min

Callum Roberts on the urgent need for marine conservation

Callum Roberts, Professor of Marine Biology at the University of York, learnt to dive in a leaky wet suit in the North Sea when he was a boy. As a student, he was introduced to the extraordinary diversity of marine life on a coral reef in the Red Sea. His job was to count different species of fish but he also noticed several different species of fish working together to defend a common resource, lurid green algal lawns. Life on coral reef is notoriously competitive and collaboration on this scal...

May 01, 201828 min

Stephen Reicher on the psychology of crowds

Stephen Reicher is a social psychologist at St Andrews University who has spent decades understanding how people behave when in a group. To do so, he's often had to immerse himself among the subjects of his studies, from the Bristol riots in 1980 to the millions of Hindu pilgrims who go to the Magh Mela. Stephen Reicher talks to Jim al-Khalili about the positive and the negative sides to a crowd and the role of a leader of a crowd. He explains how he gave up a place to read medicine, to the anno...

Mar 13, 201828 min

Clare Grey on the Big Battery Challenge

Next time you swear at the battery in your mobile phone, spare a thought for the chemist, Clare Grey. Having developed a new way of looking inside solids (using nuclear magnetic resonance), her interest in batteries was sparked by a man from Duracell who asked her a question at an academic conference, and charged up by some electrochemists she met playing squash. For the last twenty years she has sought to understand the precise chemistry of the rechargeable lithium ion battery. And her insights...

Mar 06, 201829 min

John Burn and the genetics of cancer

Professor Sir John Burn, has made Newcastle on Tyne a centre for research on genetics and disease. He was one of the first British doctors to champion the study of genes in medicine back in the 1980s. More recently his research with families with a propensity to develop certain cancers has shown the benefits of taking aspirin as a prevention against the disease. John Burn was part of the team that set up the Centre for Life on derelict industrial land near the River Tyne, where the public can wa...

Feb 20, 201829 min

Richard Henderson zooms in on the molecules of life

What once took decades, now takes days, thanks to an astonishingly powerful new technique invented by Richard Henderson, winner of the 2017 Nobel Prize for Chemistry. Richard grew up in a remote village in the Scottish borders exploring the countryside and reading the weekly bundles of comics sent by his great aunt, as part of a care package for his family. When he started work at the Laboratory of Molecular Biology in Cambridge, a string of Nobel Prizes had been awarded for x-ray crystallograph...

Feb 13, 201830 min

Wendy Barclay and the flu virus

2018 is having the worst flu season for seven years. Influenza continues to make a lot of us feel very ill, and it can of course be fatal. Wendy Barclay, Professor Virology at Imperial College London, has spent many years trying to learn everything she can about the way flu viruses behave. These microscopic infectious organisms are formidable foes - they mutate all the time, making it hard to predict which strain is going to be the one to make us sick and therefore to design effective vaccines a...

Jan 30, 201828 min

Eugenia Cheng on the mathematics of mathematics

Nothing annoys Eugenia Cheng more than the suggestion that there is no creativity in mathematics. Doing mathematics is not about being a human calculator, she says. She doesn't spend her time multiplying big numbers in her head. She sits in hotel bars drawing (mainly arrows) with a fine quill pen, thinking about how ideas from different areas of mathematics relate to one another and hoping to reveal a unifying, underlying logic to the whole of mathematics. Her area of research, Category Theory, ...

Jan 23, 201828 min

Eben Upton on Raspberry Pi

When Eben Upton was in his twenties, he wanted to get children thinking about how computers think, to boost the number of people applying to read computer science at university. He dreamt of putting a chip in every classroom. The result was Raspberry Pi, a tiny gadget, little bigger than a credit card, that can be hooked up to any keyboard and monitor, to create a programmable PC. And it's cheap. Raspberry Pi Zero, sticker price just �5, was given away free with a computer magazine in 2015. Eben...

Jan 16, 201828 min

Adrian Thomas on the mechanics of flight

As a young man Adrian Thomas took to the skies in order to better understand the mechanics of flight. He's a paragliding champion and a Professor of Zoology who specialises in the dynamics of insect flight. On a typical day, he can be found inside a wind tunnel that's been custom-made to study insects instead of jumbo jets. Using lines of smoke and high speed video cameras, he measures exactly how different insects flap their wings. When he's not writing academic papers, he's inventing clever ma...

Oct 31, 201728 min

Ellen Stofan on being NASA chief scientist

When Ellen Stofan was just four years old, she witnessed the worst rocket launch-pad disaster in NASA's history convinced that her father, (who was a rocket engineer) was on board. He wasn't. Nonetheless, for many years NASA was not her favourite place. In 2013, however, she became she became their chief scientist, a post she held for 4 years. Barak Obama dreamt of putting people on the red planet by 2032 and Ellen did everything she could to develop a realistic plan to make this happen. (A 2032...

Oct 24, 201728 min

Tim Birkhead on bird promiscuity

Professor Tim Birkhead talks to Jim Al Khalili about his 40 years of research on promiscuity in birds, his love of Skomer Island and its guillemots, and the extraordinary musical talent of the male bullfinch. Tim Birkhead is an evolutionary biologist and ornithologist at the University of Sheffield. The primary focus of his research has been reproduction in birds. He pioneered the study of promiscuity or extra-pair mating in birds, and one of its evolutionary consequences - sperm competition. In...

Oct 17, 201740 min

Steve Cowley on Nuclear Fusion

Steve Cowley has said that "fusion is arguably the perfect way to power the world". But he's had to add that "it is hard to make fusion work. Indeed, after more than 60 years of fusion research, no device has yet made more energy than it consumes". But Steve Cowley isn't giving up. He's spent over 30 years working towards making nuclear fusion a viable way of generating energy. Steve Cowley has done theoretical research on how to contain the incredibly hot material you need to get fusion going. ...

Oct 10, 201728 min

Lucie Green on the sun

Lucie Green studies the sun - that giant, turbulent ball of burning gas at the centre of our solar system. Her first ambition was to become an art therapist, but she soon switched from art to astrophysics, and before long had fixed her gaze on our local star. It may be 93 million miles away, but the sun's extensive and ever changing magnetic field determines the 'weather' throughout our solar system. Under a worst-case scenario, bubbles of super-hot plasma and streams of high energy particles - ...

Oct 03, 201728 min

Tracey Rogers on leopard seals and Antarctica

Marine ecologist Tracey Rogers talks to Jim Al Khalili about her research on one of Antarctica's top predators. This is the leopard seal - a ten foot long killer which glides among the ice floes in search of prey ranging from other seals to penguins to tiny krill. Tracey's research has encompassed the animal's prolific and eerie underwater singing to radical changes in its diet that appear to be linked to climate change. Now a senior researcher at the University of New South Wales in Australia, ...

Sep 26, 201739 min

Jennifer Doudna

Jennifer Doudna's research has transformed biology. And this is not an understatement. Her work has given us the tools to edit genes more precisely than ever before. Her scientific career began with work to understand the actions of RNA, part of the machinery of every cell. But, after a meeting in 2005 with a colleague at the University of California, Berkeley, where Jennifer is currently a professor of chemistry and of molecular and cell biology, she changed her direction of research. Through c...

Sep 19, 201728 min
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