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The Life Scientific

BBC Radio 4www.bbc.co.uk

Professor Jim Al-Khalili talks to leading scientists about their life and work, finding out what inspires and motivates them and asking what their discoveries might do for us in the future

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Episodes

Helen Hastie on the future of human-robot relations

What if robots of the future weren’t just clever machines, performing tasks in isolation, but trusted teammates you could have a chat with? That could respond naturally to conversational cues and even explain their work? Making this relationship a reality is a focus for Helen Hastie, Professor of Human-Robot Interaction and Head of the School of Informatics at the University of Edinburgh. Helen’s career has taken her from developing early dialogue systems - the ancestors of today’s generative AI...

May 19, 202628 min

Seth Berkley on the importance of vaccinating the world

Dr Seth Berkley is an epidemiologist and global health leader whose career has been shaped by one central problem: vaccines save lives, but only if people can actually get them. His 40-year career has spanned the global, from helping to build Uganda’s first HIV surveillance system and founding the International AIDS Vaccine Initiative; to leading Gavi, the Vaccine Alliance for more than a decade – overseeing the immunisation of hundreds of millions of children worldwide. And when COVID-19 struck...

May 12, 202628 min

Hiranya Peiris on unravelling the story of the universe

Hiranya Peiris is playing a starring role in a movie that promises to tell perhaps the greatest story of all time. However, it’s a movie with a difference – there’s no director and no script. The Legacy Survey of Space and Time is one of the most ambitious projects in the world of astronomy, with a mission to create a decade-long time-lapse movie of the visible universe, to answer fundamental questions about its origin, evolution and, ultimately, its fate. Hiranya is Professor of Astrophysics 19...

May 05, 202628 min

Washington Yotto Ochieng on the navigation tech that keeps our world moving

As a child growing up on the shores of Lake Victoria in western Kenya, Washington Yotto Ochieng once watched a plane cross the night sky and told his mother he wished he could travel on it. But he remembers her encouraging him to dream bigger... Today, Washington is a Professor of Engineering at Imperial College London, and President of the Royal Institute of Navigation. Over a career bridging industry and academia, he has helped shape the movement of urban transport; how satellites guide us and...

Apr 28, 202628 min

Lucy Carpenter on how our oceans are destroying ozone

Working on a remote tropical island in the Atlantic might sound like some sort of romantic idyll - but trying to conduct scientific research on a windy, isolated volanic outcrop is no picnic, as Lucy Carpenter can attest! Lucy is an atmopsheric chemist and a Professor at the University of York, whose work has helped to transform understanding of how oceans shape the air above them. She was one of the founding scientists behind the Cape Verde Atmospheric Observatory, established on São Vicente in...

Apr 21, 202628 min

Jens Juul Holst on the gut hormone discovery behind weight-loss drugs

As recently as a few years ago, the idea of a self-administered injection that would deliver proven weight-loss results might have sounded fantastical. Today, these medications are a reality and a global phenomenon; hailed in many quarters as “miracle drugs" for their success in treating obesity and diabetes. They do this by replicating a gut hormone called GLP‑1, which tells the brain you’ve eaten enough and nudges the pancreas to release insulin; and this hormone was discovered and decoded tha...

Apr 14, 202628 min

Jim Ashworth-Beaumont on how a near-fatal accident made him a better clinician

It's a rare thing to encounter a medical specialist who has experience of his field from the expert and the patient perspective - but not unheard of... Jim Ashworth-Beaumont is an orthotist and prosthetist who spent years helping people adapt to life with artificial limbs and musculoskeletal supports, before a near-fatal accident left him relying on both. This twist of fate might have derailed many - but Jim drew on reserves of resilience and determination forged long before his accident; initia...

Apr 07, 202628 min

Jehane Ragai on the science of authenticating artworks

Ever heard of the unsuccessful Dutch painter who decided to humiliate his critics by forging Vermeers, which the artworld subsequently dubbed 'masterpieces'? Or the businessman who bought a Marc Chagall painting that he displayed with pride for years, before a television investigation revealed to his horror that it was a fake? Today we're exploring the scientific techniques used to reveal forged artworks - and bring down scammers still trying to make millions from fake masterpieces. Jehane Ragai...

Jan 27, 202628 min

Tony Juniper on parrots, princes and environmental protection

Tony Juniper is an environmentalist who has worn many hats, over the course of his career. After developing a passion for birds in childhood, his first job saw him working to save endangered parrots - including a successful effort to bring back the Spix's macaw from the edge of extinction. Tony went on to hold leading campaigning roles with some of the world's best known environmental organisations, from Friends of The Earth to the World Wildlife Fund. He also acted as an advisor to King Charles...

Jan 20, 202629 min

Pierre Friedlingstein on carbon’s pivotal role in climate change

The COP30 climate summit is taking place in the Brazilian city of Belém, a gateway to the Amazon rainforest, which continues to face widespread deforestation. We all know that our climate is changing and that we are largely responsible for this, but we can’t tackle the problem unless we understand what’s going on. One scientist who’s done more than most to rectify this is Professor Pierre Friedlingstein. He’s a prominent climate scientist and Chair in Mathematical Modelling of the Climate System...

Dec 09, 202528 min

Julia Simner on tasty words and hearing colours

Imagine if you were listening to an opera or a Taylor Swift concert, and as the lights in the auditorium dimmed, the music was accompanied by a rainbow of colours only you could see. Perhaps while listening to your friends talking, you simultaneously experience a smorgasbord of tastes, with different words evoking different flavours, maybe a delicious ice cream, or something as disgusting as ear wax... This merging of the senses is known as synaesthesia, and it’s the rich research world of neuro...

Dec 02, 202528 min

Caroline Smith on meteorites and potential ancient life on Mars

Caroline Smith is passionate about space rocks, whether they’re samples collected from the surface of asteroids and the Moon and hopefully Mars one day soon, or meteorites, those alien rock fragments that have survived their fiery descents through our atmosphere to land here on Earth. She is Head of Collections and Principal Curator of Meteorites at the Natural History Museum, home to one of the finest meteorite collections in the world. Her interest in rocks began while wandering the foothills ...

Nov 25, 202528 min

AP De Silva on building molecular fluorescence sensors for healthcare

From humble beginnings in his native Sri Lanka, to a more than 40 year academic career at Queen’s University Belfast, Prof. AP (Amilra Prasanna) De Silva’s research into molecular photosensors has led to a pioneering career in that’s evolved from chemistry to medical diagnostics on one hand, to information processing on the other. Prof. De Silva challenged cultural expectations and overcame the lack of opportunities in chemistry that were available in Sri Lanka in the early 1970s. He first moved...

Nov 18, 202528 min

Peter Knight on quantum technologies

There are problems and tasks so hard and complicated that it would take today’s most powerful supercomputers millions of years to crack them. But in the next decade, we may well have quantum computers which could solve such problems in seconds. Professor Sir Peter Knight is a British pioneer in the realms of quantum optics and quantum information science. During his three decades as a researcher at Imperial College London, he has advanced our understanding of the physics which underpins how quan...

Nov 11, 202528 min

Eleanor Schofield on conserving Tudor warship the Mary Rose

In July 1545, King Henry VIII watched from Southsea Castle on England's south coast as his fleet sailed out to face the French - only to witness his prized warship, the Mary Rose, sink before his eyes. Raised from the Solent in 1982, the ship is now the centrepiece of the Mary Rose Museum, along with thousands more artefacts that were recovered from the seabed. But keeping the 500-year-old ship and its associated Tudor relics in good condition is no small task, which is where Dr Eleanor Schofiel...

Nov 04, 202528 min

George Church on reimagining woolly mammoths and virus-proofing humans

"My ideas are often labelled as impossible, or useless, or both. Usually when people say that I'm on the right track." George Church is a geneticist, molecular engineer, and one of the pioneers of modern genomics. He's also someone who makes a habit of finding solutions to the seemingly impossible. Over the course of his career so far, George developed the first method for direct genomic sequencing, helped initiate the Human Genome Project, and founded the Personal Genome Project: making huge qu...

Oct 28, 202528 min

Gareth Collett on a career in bomb disposal

Movies might have us believe that bomb disposal comes down to cutting the right wire. In fact, explosive devices are complex and varied - and learning how to dispose of them safely involves intense training, as well as the ability to stay calm under pressure. This was the world of Dr Gareth Collett, a retired British Army Brigadier General and engineer, specialising in bomb disposal; whose 32-year military career took him around the world, including heading up major ordnance clearance projects i...

Oct 21, 202528 min

Sonia Gandhi on building model brains to tackle Parkinson’s disease

Many people will be familiar with Parkinson’s disease: the progressive brain disorder that causes symptoms including tremors and slower movement, leading on to serious cognitive problems. You might not know that it’s the fastest-growing neurological condition in the world. Today it affects around 11.8 million people and that’s forecast to double by 2030. Dr Sonia Gandhi is one of the scientists working to change that trend. As Professor of Neurology at University College London and Assistant Res...

Oct 14, 202528 min

Mark O'Shea on close encounters with venomous snakes

How do you feel about snakes? What about highly venomous ones? For Mark O’Shea, close encounters with the world’s most rare and deadly snakes are not only his profession, but his passion. Mark is a Professor of Herpetology - the area of zoology focusing on reptiles and amphibians - at the University of Wolverhampton. After dropping out of college in his teens, Mark's life could have taken a very different direction; but prompted by a fascination with reptiles that started with a childhood trip t...

Oct 07, 202528 min

Kevin Fong on medical planning for Mars and Earth-based emergencies

There can't be many people in the world who've saved lives in hospital emergency rooms and also helped care for the wellbeing of astronauts in space – but Kevin Fong’s career has followed a singular path: from astrophysics and trauma medicine, to working with NASA, to becoming an Air Ambulance doctor. Kevin is a consultant anaesthetist and professor of public engagement and innovation at University College London. He’s worked on the front line in hospitals, dealing with major incidents and helpi...

Jul 15, 202529 min

Dame Pratibha Gai on training atoms to do what we want

Chemical reactions are the backbone of modern society: the energy we use, the medicines we take, our housing materials, even the foods we eat, are created by reacting different substances together. If we zoom in, it’s the atoms within these substances that rearrange themselves to give rise to new substances with the properties we need. However, chemical reactions are far from perfect. They're often inefficient and their waste products can be harmful to the environment. Getting to grips with what...

Jul 08, 202528 min

Catherine Heymans on the lighter side of the dark universe

Have you ever considered the lighter side of dark matter? Comedy has proved an unexpectedly succesful way to engage people with science - as today's guest knows first-hand. Astrophysicist Catherine Heymans is a Professor at the University of Edinburgh and the current Astronomer Royal for Scotland. She’s spent her career studying dark matter and dark energy: the mysterious ingredients that make up an estimated 95% of our cosmos, but which we still know surprisingly little about. Using increasingl...

Jul 01, 202529 min

Tim Coulson on how predators shape ecosystems and evolution

As a young man, traveling in Africa, Tim Coulson - now Professor of Zoology at the University of Oxford - became seriously ill with malaria and was told a second bout would probably kill him. Aged only 20, this brush with his own mortality led him to promise himself he would write a complete guide to science: life, the universe and everything. His aim was to understand the existence of all living things - no mean feat! Over the course of a colourful career, Tim's work has taken him all over the ...

Jun 24, 202529 min

Claudia de Rham on playing with gravity

Claudia de Rham has rather an unusual relationship with gravity. While she has spent her career exploring its fundamental nature, much of her free time has involved trying to defy it - from scuba diving in the Indian Ocean to piloting small aircraft over the Canadian waterfalls. Her ultimate ambition was to escape gravity’s clutches altogether and become an astronaut, a dream that was snatched away by an unlikely twist of fate. However, Claudia has no regrets - and says defying gravity for much ...

Jun 17, 202528 min

Neil Lawrence on taking down the 'digital oligarchy' and why we shouldn't fear AI

When you think of Artificial Intelligence, does it inspire confidence, or concern? Although it's now generally accepted that this technology will play a major role in our future, a lot of conversations around AI and machine learning come back to the argument over us losing control and robots taking over. Happily, Neil Lawrence has a more optimistic view of the power of AI, and how we might navigate the potential pitfalls. Neil is the DeepMind Professor of Machine Learning at the University of Ca...

Jun 10, 202529 min

Liz Morris on Antarctic adventures and the melting polar ice sheets

A frozen, white world at the far-reaches of the globe, where you're surrounded by snow and silence, might sound rather appealing. Factor in temperatures that drop to -57°C and a few of us might be put off - but for glaciologist Liz Morris, that's very much her happy place. Liz is an Emeritus Associate at the University of Cambridge’s Scott Polar Research Institute, and was among the first British women scientists to work on the planet’s coldest continent, Antarctica. Over the course of her caree...

Jun 03, 202528 min

Anthony Fauci on a medical career navigating pandemics and presidents

Welcome to a world where medicine meets politics: a space that brings together scientific research, government wrangling, public push-back and healthcare conspiracies… Dr Anthony Fauci was the Director of America’s National Institute of Allergy and Infectious Diseases for nearly four decades, during which time he not only helped study, treat and prevent viruses such as HIV/AIDS and Covid-19; he also advised seven US Presidents, from Ronald Regan through to Joe Biden. Along the way, Tony Fauci's ...

May 27, 202545 min

Brian Schmidt on Nobel Prize-winning supernovae and the joys of making wine

Have you ever pondered the fact that the universe is expanding? And not only that, it's expanding at an increasing speed - meaning everything around us is getting further and further away? If that isolating thought makes you feel slightly panicked, don't worry: this programme also contains wine! Brian Schmidt is a Distinguished Professor of Astrophysics at the Australian National University, known for his work on supernovae: massive explosions that take place when stars come to the ends of their...

Apr 22, 202529 min

Jacqueline McKinley on unearthing bones and stories at Britain's ancient burial sites

How much information can you extract from a burnt fragment of human bone? Quite a lot, it turns out - not only about the individual, but also their broader lives and communities; and these are the stories unearthed by Jacqueline McKinley, a Principal Osteoarchaeologist with Wessex Archaeology. During her career, Jackie has analysed thousands of ancient burial sites across the British Isles, bringing to life the old traditions around death via often cremated human remains. She's also assisted cri...

Apr 15, 202529 min

Jonathan Shepherd on a career as a crime-fighting surgeon

Surgeons often have to deal with the consequences of violent attacks - becoming all too familiar with patterns of public violence, and peaks around weekends, alcohol-infused events and occasions that bring together groups with conflicting ideals. Professor Jonathan Shepherd not only recognised the link between public violence and emergency hospital admissions, he actually did something about it. As a senior lecturer in Oral and Maxillofacial Surgery in the early 1980s, Jonathan started looking i...

Apr 08, 202529 min
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