This is a joint podcast between The Lancet Rheumatology and The Lancet Regional Health - Western Pacific with Prof Xue Li. Biologics have become a mainstay of treatment in Rheumatology in Western populations, but in many parts of Asia, especially lower-and-middle-income countries, there remains substantial inequity in access due to differences in availability and affordability. In this episode, we explore the factors that may have delayed the popularisation of biologics in Asia, any recent polic...
Jun 20, 2025•20 min
In this podcast, Professor Savic talks about his recent publication that looks at treatment outcomes in patients with VEXAS syndrome, as well as what clinicians should look out for in patients (red flags), and future priorities for research. VEXAS syndrome (short for Vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic syndrome) was first described in 2020. It’s a rare, and often-life threatening, inflammatory condition primarily affecting men. It's caused by a mutation in the UBA1 gene, lea...
Jun 16, 2025•12 min
This is the third and final episode of our mini-series on cell-based therapies in rheumatology, with Professor Fabian Müller and Dr Melanie Hagen from the Erlangen University, Germany. We discuss their recently published a study on a newly discovered toxicity of CD-19 targeting CAR T-cell therapy in patients with autoimmune disease, as well as the recent successes of CAR T-cell therapy, ideal patient selection, and future directions. Read the full article: https://www.thelancet.com/journals/lanr...
Jun 03, 2025•21 min
This is the second episode of a mini series on cell-based therapies in rheumatology, with Prof. Dominique Farge discussing the use of allogeneic umbilical cord-derived mesenchymal stromal cells (MSCs) as treatment for systemic lupus erythematosus (SLE). We cover the limited options currently available for people with severe or refractory SLE, the complexities in using MSCs, Prof. Farge's recent study results, and how these results fit in with the evidence available, as well as the future for thi...
Apr 25, 2025•26 min
The first episode of a mini series on cell-based therapies in rheumatology, with Prof Rebecca Marsh and Grant Schulert discussing the use of allogeneic haematopoietic stem-cell transplantation for children with refractory systemic juvenile idiopathic arthritis and associated lung disease. Read the full article: https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(24)00275-3/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanrhe Continue this conversation on social! Follow us today at......
Mar 24, 2025•19 min
Dr Bryant England discusses the use of TNF-inhibitor versus non-TNF inhibitor biological or targeted synthetic DMARDs for treatment of rheumatoid arthritis-associated ILD, and the effects on survival and respiratory hospitalisation outcomes. Read the full article: https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(24)00265-0/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanrhe Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagra...
Feb 24, 2025•9 min
Dr Brooke Conley and Associate Professor Ivan Lin discuss their recent study on integrating evidence from lived experience of Aboriginal people and clinical practice guidelines to develop arthritis educational resources. Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv...
Jan 27, 2025•19 min
Dr Mark Russell and Sherry Yang discuss the factors influencing initiation of biologics in underserved populations with rheumatoid arthritis in the UK, how historical redlining and present-day racialised economic segregation affects health-care utilisation of adults with rheumatic diseases in the USA, and health inequities seen in rheumatology more broadly. Read the full article: https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(24)00221-2/fulltext?dgcid=buzzsprout_icw_podcast_gene...
Dec 23, 2024•25 min
Dr Quirine Dumoulin discusses the efficacy of a 1-year course of methotrexate on the development of rheumatoid arthritis in ACPA-negative people with clinically suspect arthralgia and predicted increased risk of rheumatoid arthritis. Read the full article: https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(24)00196-6?dgcid=buzzsprout_icw_podcast_generic_lanrhe Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgr...
Nov 25, 2024•16 min
Dr Sebastian Sattui discusses the effects of age and frailty on the risks of end-stage renal disease, death, and severe infection in older adults with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. Read the full article: https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(24)00193-0/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanrhe Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup http...
Oct 21, 2024•26 min
To celebrate 5 years of The Lancet Rheumatology , international advisory board members Oliver Distler, Laura Coates, and David Liew discuss recent progress made, challenges to overcome, and future directions in rheumatology. Read the associated Editorial: https://www.thelancet.com/journals/lanrhe/article/PIIS2665-9913(24)00245-5/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanrhe Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/the...
Sep 23, 2024•58 min
Dr Karen Schreiber, Professor Ian Giles, and Professor Angela Tincani discuss the Series on Pregnancy and Rheumatic Diseases, including the use of DMARDs during pregnancy, study design and conduct, and outcomes for children born to mothers with rheumatic diseases. Read the Series: https://thelancet.com/series/pregnancy-rheumatic-diseases?dgcid=buzzsprout_icw_podcast_generic_lanrhe Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/the...
Jul 22, 2024•35 min
Dr Maria Tektonidou discusses the results of a cross-sectional analysis of international data on cardiovascular risk factors in systemic lupus erythematosus. Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv...
Jun 17, 2024•11 min
Dr Rosemary Hollick, University of Aberdeen, discusses a mixed-methods study on key health system components associated with improved outcomes to inform the re-configuration of services for adults with rare autoimmune rheumatic diseases. Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv...
May 21, 2024•16 min
Editors Heather Van Epps and Anna Clark join guest hosts Lola Falasinnu, David Liew, and Puja Mehta to reflect on the progress of The Lancet Rheumatology and share their vision for the future. Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv...
Jan 18, 2023•26 min
Dr Shirin Heidari, Prof James Wason, Dr Karen Schreiber, and Prof Cheryl Barnabe join guest host Dr David Liew to discuss how sex and gender impact research design and reporting and improvements that can be made. Learn more: The Lancet Summit: Sex and gender in rheumatology Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://yout...
Oct 12, 2022•39 min
Drs. Randy Cron and Chandrika Bhat join guest host Dr Puja Mehta to discuss the opportunities and challenges of cross-speciality research. Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv...
Aug 25, 2022•33 min
Prof Michael Weisman joins guest host Dr Lola Falasinnu to discuss the challenges of conducting clinical trials in rheumatology and recent developments in trial design. Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv...
Jul 28, 2022•35 min
Prof Catherine Nelson-Piercy and Dr Lizemarie Wium join guest host Dr Puja Mehta to discuss the importance and challenges of obstetric medicine in rheumatic diseases. Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv...
Jun 23, 2022•32 min
Greta Lindenmayer, Stephen Brady, and Onika Paolucci join guest host David Liew to discuss specialist considerations for the care of Australian Aboriginal patients with lupus. Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv...
May 31, 2022•37 min
Clinical Realities: Duncan Porter and Shahir Hamdulay discuss the challenges facing rheumatology care in the UK in 2022, and what's needed to improve care in the coming years. Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv...
Apr 25, 2022•29 min
Dr. Thomas Bush joins guest host Dr. Lola Falasinnu to discuss climate change and the potential adverse health effects of climate hazards for patients with rheumatic diseases. Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv...
Mar 24, 2022•24 min
Dr. Coziana Ciurtin and Dr. Kate Webb join guest host Dr. Puja Mehta to discuss the challenges and opportunities involved in transitional care for adolescent patients with rheumatic diseases as they progress to adulthood. Read the profile of Puja: Puja Mehta: taking the path untrodden Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet h...
Feb 24, 2022•31 min
Dr. Dzifa Dey joins guest host Dr. David Liew to discuss innovations in providing specialist rheumatology care and patient education in Ghana, and how her experiences in Africa could help inform development of rheumatology care in other low-resource settings. Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelanc...
Jan 27, 2022•29 min
Dr. Eric Peters and Prof. Jinoos Yazdani join Editor-in-Chief Heather Van Epps to discuss the challenges of providing specialist rheumatology care to undocumented immigrants in the USA. Continue this conversation on social! Follow us today at... https://thelancet.bsky.social/ https://instagram.com/thelancetgroup https://facebook.com/thelancetmedicaljournal https://linkedIn.com/company/the-lancet https://youtube.com/thelancettv...
Dec 22, 2021•23 min
