The Kidney Chronicles: A Pediatric Nephrology Podcast - podcast cover

The Kidney Chronicles: A Pediatric Nephrology Podcast

Emily Zanglazangl015.podbean.com
Introducing “The Kidney Chronicles: A Pediatric Nephrology Podcast,” produced and hosted by Drs. Emily Zangla, Kelly Garrity, Jason Misurac, Vivian Shih and Anne Kouri. We interview experts in the field to provide high quality info and “tricks of the trade” that are valuable for clinicians to use in practice. It’s a great way to learn and to bring together the peds nephrology community across the country (and maybe even world)! We want to hear any requests for future episodes, experts who want to come onto our show and your feedback! Email Emily at doctoremilyz@gmail.com. Artwork done by Shannon Luker, https://www.shannonluker.com/.
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Episodes

Episode 45: Chronic Hemodialysis Part 2

Join us for Part 2 as we discuss the management of pediatric chronic hemodialysis and troubleshooting common complications. Guest experts include: Dr. Cherry Mammen, Assistant Professor and Dialysis Director at British Columbia Children's Hospital, Dr. Raj Munshi, Associate Professor and Dialysis Director at Seattle Children's, and Dr. Sarah Swartz, Assistant Professor and Dialysis Director at Texas Children's.

Jan 02, 202651 minEp. 45

Episode 44: Dialysis Nutrition Part 2

Dr. Molly Vega, RD and PhD at Texas Children's and Nonnie Polderman, RD at British Columbia Children's Hospital provide their expertise on pediatric dialysis nutrition considerations, specifically in the realm of chronic hemodialysis. -Visit https://www.espn-online.org/nutrition-taskforce/ to see the clinical practice guidelines published by the Paediatric Renal Nutrition Taskforce

Dec 02, 202535 minEp. 44

Episode 43: Dialysis Nutrition Part 1

Dr. Molly Vega, RD and PhD at Texas Children's and Nonnie Polderman, RD at British Columbia Children's Hospital provide their expertise on pediatric dialysis nutrition considerations, specifically in the realms of acute kidney injury and CRRT. -Visit https://www.espn-online.org/nutrition-taskforce/ to see the clinical practice guidelines published by the Paediatric Renal Nutrition Taskforce

Nov 04, 202530 minEp. 43

Episode 42: Chronic Hemodialysis Part 1

We discuss initiation and considerations of pediatric chronic hemodialysis as well as the monthly visit and importance of an interdisciplinary team. Guest experts include: Dr. Cherry Mammen, Assistant Professor and Dialysis Director at British Columbia Children's Hospital, Dr. Raj Munshi, Associate Professor and Dialysis Director at Seattle Children's, and Dr. Sarah Swartz, Assistant Professor and Dialysis Director at Texas Children's. References HD dose and UF rate associated with survival in p...

Oct 05, 202557 minEp. 42

Episode 41: Atypical Hemolytic Uremic Syndrome

Dr. Carla Nester, Professor of Pediatrics and Internal Medicine and Division Director of Pediatric Nephrology as well as the Associate Director of Molecular Otolaryngology and Renal Research Laboratory at the University of Iowa and international expert in Complement Disorders, discusses atypical HUS. She reviews the pathophysiology, clinical presentation, evaluation, management and transplant considerations.

Sep 06, 202554 minEp. 41

Episode 40: Hypertension Part 2

In this second episode of our two part series on pediatric hypertension, we talk to Dr. Tammy Brady, a pediatric nephrologist at Johns Hopkins, and Dr. Joshua Samuels, both a pediatric and adult nephrologist at University of Texas Houston. In this episode they review validated blood pressure cuff, home blood pressure monitoring, inpatient blood pressure concerns, end organ cardiac changes, end organ cardiac impacts of hypertension, and choice of antihypertensive.

Aug 03, 202556 minEp. 40

Episode 39: Hypertension Part 1

In this first episode of our two part series on pediatric hypertension, we talk to Dr. Tammy Brady, a pediatric nephrologist at Johns Hopkins, and Dr. Joshua Samuels, both a pediatric and adult nephrologist at University of Texas Houston. In this episode they review ambulatory blood pressure monitors, the basis for our standards for diagnosing pediatric hypertension, the pathophysiology behind obesity increasing the risk of developing hypertension, and ensuring blood pressure is accurately measu...

Jul 01, 202550 minEp. 39

Episode 38: Congenital Anomalies of the Kidney and Urinary Tract- A Parent Perspective

On this episode, we discuss all things CAKUT-related with the Neonatal Kidney Collaborative. Guests include Dr. Sangeeta Hingorani, a pediatric nephrologist at Seattle Children’s, Dr. Samantha Schwartz, a Six2 crew member and pediatric nephrology fellow at Lurie Children's, Kara Short, a nephrology nurse practitioner at the University of Alabama, Dr. Cara Slagle, a Neonatologist at Indiana University and Lakesha, mother of Landon, a nephrology patient at the University of Alabama. This is a spec...

Jun 05, 202551 minEp. 38

Episode 37: Urinary Tract Infections

In this episode of the podcast we focus on recurrent urinary tract infections, looking at how we diagnose UTIs, the diagnostic challenges, the causes of recurrent UTIs, and the management. We interview Dr. John David Spencer the division chief of pediatric nephrology at Nationwide Children's Hospital and Dr. David Hains the division chief of pediatric nephrology at Riley Children's Hospital who are both experts on the topic with extensive research into this arena and numerous publications. Marsh...

May 12, 202557 minEp. 37

Episode 36: NephMadness 2025 Minimal Change Disease in Kids

A NephMadness special episode on minimal change disease in kids, supported by the AJKD and NKF. Guests include Dr. Alvarez Elias, who is an AJKD executive team member, pediatric nephrologist and research scientist at Fresenius, and Dr. Mallory Downie, a pediatric nephrologist at McGill University with her own lab studying genetics behind kidney disease in kids, specifically nephrotic syndrome. We discuss the exciting pathophysiology breakthroughs in MCD and treatment of relapses. Please particip...

Mar 09, 202545 minEp. 36

Episode 35: Transition from Pediatric to Adult Care

Dr. Maria Diaz-Gonzalez de Ferris, MD, MPH, PhD, joins us for a conversation about her approach to transitions of care in Nephrology. She is a pediatric nephrologist at UNC Chapel Hill, the Director of the UNC Transition Program otherwise known as STARx. Through her research work focusing on healthcare transitions for children with medical complexity, she has developed a system of healthcare checkpoints and resources that assess autonomy and self-management. In this episode, we briefly discuss t...

Feb 20, 202547 minEp. 35

Episode 34: Acute Kidney Injury

Drs. Stu Goldstein, Professor & Director of the Center of Acute Care Nephrology at Cincinnati Children's, and Jordan Symons, Professor, Fellowship Program Director and Apheresis Director at Seattle Children's Hospital provide their expertise regarding pediatric acute kidney injury. We discuss the emergence of the sub-specialty of critical care nephrology, harms of fluid overload, utility of biomarkers, benefits of early AKI awareness and CRRT therapy and an individualized approach to the ped...

Jan 03, 202559 minEp. 34

Episode 33: ARPKD

For this episode on ARPKD interviewed Dr. Lisa Guay-Woodford a clinician scientist at Children’s Hospital of Philadelphia who is a world-renowned expert on cystic kidney diseases. She was part of one of the teams that discovered the ARPKD gene and provides fascinating insight into the history and management of the condition. References ARPKD genetic variations: https://www.sciencedirect.com/science/article/abs/pii/S1096719209002947 Bilateral nephrectomy outcomes: https://www.nature.com/articles/...

Dec 05, 202453 minEp. 33

Episode 32: Kidney Health Monitoring in NICU Graduates

We talk to the experts in the Neonatal Kidney Collaborative (NKC) about the recently published guidelines regarding kidney follow-up for NICU graduates, a product of the NIH-supported workshop in 2024 spearheaded by Dr. Michelle Starr of Indiana University/Riley Children's Hospital. Guests include Dr. Marissa DeFreitas, pediatric nephrologist at the University of Miami, Dr. Matt Harer, neonatologist at the University of Wisconsin, Dr. Kat Gist, pediatric cardiac intensivist at Cincinnati Childre...

Nov 01, 202452 minEp. 32

Episode 31: Genetic Testing

Dr. Matthew Sampson, a pediatric nephrologist and associate professor of pediatrics at Harvard Medical School, walks us through genetic testing for pediatric patients with kidney disease. He discusses indications for genetic testing and how to interpret results. He also talks about his lab and work as a genomics researcher. Episode References Sampson Lab: https://www.sampsonlab.org/ ClinVar: https://www.ncbi.nlm.nih.gov/clinvar/ KDIGO genetic testing guidelines: https://kdigo.org/wp-content/uplo...

Oct 07, 20241 hr 2 minEp. 31

Episode 30: Anemia of Chronic Kidney Disease

Join us for an episode on anemia of chronic kidney disease with two pediatric nephrology experts on the topic, Dr. Meredith Atkinson, Associate Professor of Pediatrics at Johns Hopkins, and Dr. Mark Hanudel, Associate Professor of Medicine at UCLA. We will explore the underlying mechanisms behind anemia of CKD, novel treatments for anemia, thoughts on preventing hemoglobin cycling in the setting of Epoetin Alfa, and various iron supplementation tips.

Sep 06, 202446 minEp. 30

Episode 29: Timing of Kidney Replacement Therapy

Join us for a journal-style episode covering 2023 CJASN article, "Timing of Kidney Replacement Therapy among Children and Young Adults." Drs. Nick Larkins and Simon Carter discuss the findings from the Australia and New Zealand Dialysis and Transplant Registry and compare and contrast it to United States, Canada and European data. Article link: https://pubmed.ncbi.nlm.nih.gov/37279903/

Jun 04, 202438 minEp. 29

Episode 28: Calcium and phosphorus disorders

Dr. Clemens Bergwitz, an associate professor of endocrinology at Yale University, walks us through how to work-up and treat patients with calcium and phosphorus disorders. He helped to discover the disease HHRH (hereditary hypophosphatemic rickets with hypercalciuria) and has wonderful knowledge to share with listeners regarding the bone-mineral axis! References 2024 KIR Update on HHRH https://pubmed.ncbi.nlm.nih.gov/38364990/ 2009 Ped Nephrology Genetic causes of hypercalciuric nephrolithiasis ...

Apr 04, 202452 minEp. 28

Episode 27: Hyperoxaluria and miscellaneous stone management

Join us to learn about hyperoxaluria from nephrolithiasis expert and division director of pediatric nephrology at Mayo Clinic, Dr. David Sas! We discuss pathophysiology, work-up and management of primary hyperoxaluria, including new game-changing therapies. Dr. Sas also answers other high-yield kidney stone management questions. Resources: Novodetect primary hyperoxaluria/nephrolithiasis genetic panel testing: file:///Users/student/Downloads/BpG_GTP-for-NovoDetect-Panels-Form_GTP-NVDT-2P-B.pdf R...

Mar 18, 202445 minEp. 27

Episode 26: SGLT-2 Inhibitors

Dr. Laura Hesemann, a med/peds-trained adult and pediatric nephrologist and Chair of Pediatrics at the University of Missouri, shares her expertise about SGLT-2 inhibitors and their utility in clinical practice.

Feb 01, 202427 minEp. 26

Episode 25: Pediatric dialysis directorship

Drs. Donna Claes, Vivian Shih and Annie Kouri (our co-host) discuss their roles as pediatric dialysis directors at their institutions. Donna Claes is an associate professor of pediatric nephrology and chronic dialysis director at Cincinnati Children's and Vivian Shih is an assistant professor of pediatric nephrology and acute dialysis director at Children's Hospital Colorado. We talk about the road to becoming a dialysis director, what the job entails, the challenges, the rewarding aspects of th...

Jan 04, 202447 minEp. 25

Episode 24: Post-transplant FSGS Recurrence

Dr. Katherine Twombley, professor and chief of pediatric nephrology at the Medical University of South Carolina, shares her knowledge on FSGS recurrence after transplant. She discusses the diseases that cause FSGS and her strategy for managing these complex patients. Dr. Twombley is the director of dialysis and kidney transplantation, and does clinical research in the area of transplant. She is involved with leadership roles both in ASPN and AST. If you have any feedback or would like to come on...

Dec 04, 202339 minEp. 24

Episode 23: Transplant Directorship

As part of the leadership series of podcast episodes, this episode discusses life as a pediatric kidney transplant director. Dr. Jodi Smith, Seattle Children's transplant director and ASPN president, Dr. Gina Barletta, Phoenix Children's transplant director, and Dr. Sarah Kizilbash, co-host and University of Minnesota transplant director, talk about why and how they got to be transplant director, their program's structure, strengths, weaknesses and the greatest joys of their job. For more inform...

Nov 14, 202339 minEp. 23

Episode 22: Leadership from Academia to Pharma

Join us in our discussion with Dr. Deepa Chand, who is a pediatric nephrologist, former dialysis and division director, and now director of patient safety in immunology at Novartis. She also continues to practice pediatric nephrology at the University of Illinois-Peoria. She talks about her journey to where she is today, behind-the-scenes information regarding drug development and approval, and provides practical advice that is valuable for clinicians and researchers alike.

Oct 04, 202335 minEp. 22

Episode 21: Division Directorship

This is the first episode in our leadership series! We talk with Drs. Sudha Garimella, associate professor of pediatrics at Prisma Health, and Priya Verghese, professor of pediatrics at Lurie Children's/Northwestern University about their roles as division directors in pediatric nephrology. They discuss their career paths, challenges and rewards of the job, tips for recruitment and general leadership advice, helpful for all pediatric nephrologists! ASNP

Aug 29, 202341 minEp. 21

Episode 20: Post-Transplant Lymphoproliferative Disorders

Dr. Vikas Dharnidharka, Professor of Pediatrics and Pediatric Nephrology Division Director at Washington University School of Medicine in St. Louis, shares his extensive knowledge on PTLD (post-transplant lymphoproliferative disorders) in pediatric kidney transplant recipients. He is the first author of a PTLD textbook ( https://link.springer.com/book/10.1007/978-3-030-65403-0 ) and has published numerous studies and guideline recommendations on the subject. We discuss the pathophysiology, risk ...

Aug 03, 202331 minEp. 20

Episode 19: IgA Nephropathy- Adult versus Pediatric Perspectives

We have two fantastic Canadian guest nephrologists discussing IgA nephropathy on this episode. Dr. Sean Barbour is an adult nephrologist and associate professor at the University of British Columbia. He is a glomerulonephritis and epidemiology expert and serves as the chair of the British Columbia GN Committee and Registry. He developed and validated the IgA clinical prediction tool for both adults and children and has participated in the TESTING and NefIgArd clinical trials. Dr. Alexandra Cambi...

Jul 05, 202344 minEp. 19

Episode 18: Applying to Pediatric Nephrology Fellowship

Join us for this special episode regarding how to apply for pediatric nephrology fellowship. We will give residents the inside scoop on succeeding in landing their top match in the application and interview process! Guests on this podcast are pediatric nephrology program directors- Drs. Erum Hartung (CHOP), Julie Goodwin (Yale), Elizabeth Ingulli (UCSD/Rady Children's), Carla Nester (University of Iowa) and current pediatric nephrology fellows- Emily Zangla (University of Minnesota), Carlos Bece...

May 31, 202354 minEp. 18

Episode 17: Neonatal Dialysis

Join us for the discussion on neonatal dialysis with expert Dr. David Askenazi from the University of Alabama who pioneered the adaptation of the Aquadex machine to infants! We cover acute kidney injury, the utilization of peritoneal dialysis, CRRT, Aquadex and Carpediem in neonates and the logistics behind the use of these novel new machines. To get involved, visit the Neonatal Kidney Collaborative website at: https://babykidney.org/ High-yield papers on neonatal AKI and dialysis: AWAKEN Study:...

May 04, 202339 minEp. 17

Episode 16: The Golden Age of Lupus Nephritis

Dr. Brad Rovin, director of the Division of Nephrology and the Vice Chair of Research in Internal Medicine at the Ohio State University, discusses recent advances in lupus nephritis treatment. Dr. Rovin is deputy editor of Kidney International and the co-chair of glomerular disease guidelines for KDIGO. He has published many major landmark nephrology clinical trials in lupus nephritis (listed below), which he highlights in this episode. It's the "golden age" of lupus nephritis treatment! Papers ...

Mar 30, 202330 minEp. 16
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