Chronologically, you get 1 year older every year. But how old are you getting biologically? In order to optimize longevity, you need to understand biological aging. With all the different longevity and biological aging tests, it can be difficult to understand where to start. Fortunately, we got Ryan Smith from Tru Diagnostic on todays episode to guide you on all things longevity and biological aging. In this episode, Ryan highlights the different biological aging tests and which one is the most ...
Sep 22, 2023•1 hr 40 min•Season 4Ep. 5
Is the ApoE gene solely a predictor of cognitive decline, or is it just one piece of a larger, more intricate puzzle? In today's episode, we focus on the ApoE gene, a genetic player that’s most notoriously linked to Alzheimer's Disease. Julia dives deep into the three major variants called E2, E3, and E4, discussing how they change the shape of the ApoE protein and impact how well it functions. she also opens up the curtain on other health issues that can be caused by the ApoE gene —impacting yo...
Sep 15, 2023•6 min
Why are there so many different versions of the same supplement? Is it all just a marketing ploy, or do they all have different effects on your health? In this episode, Emiel Bakker from Nootropics Depot comes on to dive into the complex world of dietary supplements, where not all products are created equal. He gives us an inside look at the science behind developing a supplement, from deciding on an extraction method to choosing between a fruiting body vs. mycelium. We uncover the nuanced facto...
Sep 08, 2023•1 hr 33 min•Season 4Ep. 3
How can you measure autophagy for certain? And what are the key stages to an effective fasting regimen? Returning guest, Dr. Joseph Antoun from L-Nutra, the visionary company spearheading the fast-mimicking diet revolution, is here to answer these questions. In this enlightening conversation, we delve into: New clinical trials that prove the fast-mimicking diet not only mimics fasting but enhances the benefits. The science of autophagy: What it is, its tremendous health benefits, and groundbreak...
Sep 01, 2023•1 hr 18 min•Season 4Ep. 2
Welcome back to SNPits, a short form series helping you decode your DNA, one gene at a time. In this episode, we delve into the fascinating world of the COMT gene, commonly dubbed the "Warrior/Worrier" gene. We unpack the science behind this gene's influence on stress regulation, emotional resilience, and even cognitive function. Is the "Warrior/Worrier" label an oversimplification, or does it offer a genuine glimpse into our genetic predisposition? Whether you're well-versed in genetics or just...
Aug 25, 2023•4 min
Join us as we dive deep into the world of genomics, nutrition, and precision health with Dr. Greg Nacarelli, a leading expert in naturopathic medicine and genetics. Dr. Nacarelli delves into the intricate interplay of genetics, environment, and lifestyle on our health, explaining why personalizing health care is the future. Greg touches on the value of understanding individual genetic profiles and how this can be utilized for personalized nutrition and health coaching. With extensive academic qu...
Aug 18, 2023•41 min•Season 4Ep. 2
Dive deep into the intricate world of gut health with the pioneer himself, Dr. Steven Gundry. Once dismissed as pseudoscience, the concept of 'leaky gut' has become a cornerstone of modern health understanding, and no one knows this better than Dr. Gundry. In this enlightening episode, we unravel the real science behind leaky gut, the dangers of food sensitivities, and the profound effects of glyphosate on our system. Beyond just understanding, Dr. Gundry shares actionable insights on optimizing...
Aug 11, 2023•1 hr 20 min•Season 4Ep. 1
Welcome to SNPits, a new, short-form podcast series that takes you on a deep dive into specific genes, unraveling the science behind them and their impact on health. In this episode, we tackle the MTHFR gene and its rise to fame. We explore how 'typos' in our genes, known as SNPs, influence our health, and dive into the debate surrounding one of the most studied genes in the world. Is the MTHFR gene truly a culprit in conditions like heart disease and chronic fatigue, or is it a scapegoat? Join ...
Aug 04, 2023•5 min
To celebrate the richness of this season, we've compiled the most powerful insights and the unforgettable moments into a special "Best of Season 3" episode. From experts breaking down complex health subjects to invaluable pieces of advice on achieving your healthiest self, this episode is your ultimate guide to the knowledge treasure of Season 3.
Jul 25, 2023•26 min
Is anxiety truly genetic? How do our genes and environment shape our response to stress? Are we all experiencing the world differently based on our unique biochemical make-up? In this episode, Joe and Dr. Greg (SelfDecode Health Expert) dive deep into the realm of anxiety, answering questions from the SelfDecode community and unmasking the role our brain's biochemistry plays in the expression of anxiety. Joe and Greg discuss the role of mental health in overall wellness and highlight specific ge...
Jul 14, 2023•51 min•Season 3Ep. 12
What’s the difference between genomics and genetics? How important is it to understand your genes when looking at optimizing your health? In this episode, Dr. Anil Bajnath and Joe delve into the world of DNA and their impact on our health. Dr. Bajnath breaks down complex health science concepts in a way that's easy to understand, while sharing his unique approach to healthcare. Some highlights of the episode include: ✔️ Understanding the difference between genomics (the study of all genes in our...
Jul 07, 2023•1 hr 35 min•Season 3Ep. 11
Are supplements as strong as drugs? Dr. Tyler Panzner is this episode's guest, bringing his expertise on the role of genetics and supplements in combating common ailments such as IBS, anxiety, and insomnia. As a champion for understanding our body’s pathways, Dr. Panzner's approach is transforming our understanding of chronic disease and health management. Dr. Panzner dives deep into the crucial topic of understanding and supporting our body’s most commonly mutated pathways, rather than getting ...
Jun 30, 2023•1 hr 9 min•Season 3Ep. 10
Vince Giuliano is back, and this time, he’s discovered something about aging that may blow your mind. Vince Giuliano is living a healthy and active life at the young age of 93, and is committed to continue doing research on longevity and increasing lifespan even at this age! In this episode, Vince Giuliano and Joe discuss how supplements truly affect aging and how Vince has changed his perspective on longevity and the factors that affect it. Vince talks about his new theory, which compares the h...
Jun 23, 2023•54 min•Season 3Ep. 9
In this episode, Joe sits down with biohacker and health expert, Anthony DiClementi. Best known for his revolutionary work in the biohacking space, Anthony shares a wealth of knowledge drawn from his 20+ years of experience biohacking himself and his clients with biohackingcoach.com. Anthony highlights the surprising, often overlooked factors contributing to bad health in the US, particularly focusing on the hidden toxins in our foods, the way cities are built, and the culture surrounding social...
Jun 16, 2023•59 min•Season 3Ep. 8
In this episode of The Joe Cohen Show, Joe sits down with Chief Scientific Officer of MitoQ, Dr. Siobhan Mitchell. Siobhan shares her impressive academic and industry experience and knowledge to explore mood, cognitive function, and mitochondrial health. Her industry experience includes giants like Unilever, Nestle, PepsiCo, and Noom, where she worked on the fascinating effects of nutrition on mood and cognition. Siobhan and Joe do a deep dive into the serotonin-mood connection, helping us under...
Jun 09, 2023•1 hr 26 min•Season 3Ep. 7
How can you use your biomarkers to create the optimal diet and supplement regimen for YOU? In this episode, Ari and Joe discuss how, similar to DNA, even optimal lab levels are personalized based on your unique body. Ari talks about the problem with only focusing on 1 biomarker, and lets you in on important things to look out for when optimizing energy and focus. They discuss the importance of AI and big data to health, and discuss the growing wearable market and how big of an impact this will h...
Jun 02, 2023•1 hr 39 min•Season 3Ep. 6
This episode was originally published on April 18th, 2017 on SelfHacked Radio - now known as The Joe Cohen Show. It's been 6 years since this episode aired, and yet a lot of health issues that were mentioned, alongside revolutionary health strategies that Dr. Gundry shares, are still more relevant than ever! In an episode that clearly shows Dr. Gundry was way ahead of his time, Joe and Steven Gundry discuss the prominence of leaky gut, how inflammation is the cause of the majority of health issu...
May 26, 2023•1 hr 9 min
Does a fast-mimicking diet give you the same benefits as a 5-day water fast? How important is periodic fasting - also known as prolonged fasting - to your health? What is the best length of an intermittent fast? In this episode of The Joe Cohen Show, we dive deep into the world of fasting with our guest Dr. Joseph Antoun from L-Nutra, the pioneering company behind the revolutionary fast-mimicking diet. We discuss the science and mechanisms behind the fast-mimicking diet, exploring how it allows ...
May 19, 2023•41 min•Season 3Ep. 5
Have you ever wondered what separates elite athletes and Navy SEALs from the rest of us? How do they optimize their physical and mental performance? In this episode, Andrew Herr - who has led human performance and biotech strategy efforts for the U.S. military and ran R&D strategy efforts to get Navy SEALs ready to deploy - comes on the show to share his secrets to hack your recovery, improve your cognitive function, and optimize your stress management techniques. Plus, Andrew talks about th...
May 12, 2023•56 min•Season 3Ep. 4
Is cholesterol good or bad for you? How should you treat your serum cholesterol levels in the blood? Is LDL-C the best marker to look at when analyzing your cardiovascular health? In this episode, Joe dives deep into the complex and controversial world of cholesterol, examining the ongoing debate around its impact on cardiovascular health. First, he breaks down the different viewpoints that dominate the topic of cholesterol, discussing the positives and negatives of each one. He also delves into...
May 08, 2023•36 min•Season 3Ep. 3
Do you ever feel like you're walking on a tightrope, unsure of what foods might trigger an unwanted reaction? Well, you're not alone. Food sensitivities are more common than ever, and they can cause a whole host of issues ranging from digestive discomfort to brain fog. After years of research and experimentation, and with the help of SelfDecode, Joe found what he think is a break through in reversing food sensitivities. Now, he can eat things that he never thought possible a few years ago. So he...
Apr 28, 2023•48 min•Season 3Ep. 2
How important is it for you to test and track your lab markers? Are some tests more important than others? Are functional lab tests useless, or is it just the way that companies are interpreting the data that renders it useless? In this eye-opening episode, we brought on Dr. Chris Masterjohn and Dr. Tommy Wood to dive deep into understanding the complexities of test results, vitamin and mineral deficiencies, and genetic predispositions. Chris and Tommy use their years of expertise and tremendous...
Apr 21, 2023•1 hr 20 min•Season 3Ep. 1
To celebrate the end of Season 2, we’ve gathered the top 10 moments of The Joe Cohen Show and compiled them into a single podcast episode! These moments were voted on by Joe, employees of SelfDecode, and listeners of The Joe Cohen Show. It includes clips filled with valuable knowledge on different health topics and actionable takeaways that you can implement in your daily life. Full The Joe Cohen Show Episode links: Stacy Sims Dominik Nischwitz Richard Miller Molly Maloof Chris Masterjohn Alex L...
Apr 14, 2023•57 min
Longevity is a concoction of many different things - VO2 max, HRV, telomere length, blood pressure, mTOR and AMPK, and so much more. Optimizing and improving your lifespan requires a balanced focus on all of these through lifestyle, diet, and supplement implementations. Dr. Jeffrey Gladden - a Board certified interventional cardiologist and the founder of Gladden Longevity - is the guest of today's episode! We explore the different strategies that claim to improve longevity and dive deep into th...
Apr 07, 2023•1 hr 9 min•Season 2Ep. 14
In our Health Analysis Series, Joe Cohen, expert biohacker and founder of SelfDecode, brings on a guest, and together they utilize the power of DNA and labs to assess, discuss, and recommend ways to further optimize their health. Our guest today is Briana Theroux, a health professional certified by the Institute for the Psychology of Eating who has over a decade of experience biohacking her health. In episode 2 of this 2 part series, Joe and Briana analyze her DNA results on SelfDecode, as well ...
Mar 31, 2023•1 hr 3 min•Season 2Ep. 13
In our Health Analysis Series, Joe Cohen, expert biohacker and founder of SelfDecode, brings on a guest, and together they utilize the power of DNA and labs to assess, discuss, and recommend ways to further optimize their health. Our guest today is Briana Theroux, a health professional certified by the Institute for the Psychology of Eating who has over a decade of experience biohacking her health. In episode 1 of this 2 part series, Briana goes over her health history, discusses some of the gam...
Mar 24, 2023•59 min•Season 2Ep. 12
Biological age is a critical indicator of our overall health and wellness. It's a measure of how well our body functions compared to others of the same chronological age. But are all biological age tests the same? Are some more accurate indicators than other? In this episode, Alex Leaf and I discuss the lifestyle factors that contribute to biological aging, such as diet, exercise, and stress management, and how we can make changes to improve our health and wellbeing. We also talk about body imag...
Mar 19, 2023•1 hr 30 min•Season 2Ep. 12
Optimal nutrition is different from person to person, and even moreso from sex to sex. Men and women have many physiological differences that can truly change how to approach your health and fitness. Are cold plunges good for men and women? What about saunas? Dr. Stacy Sims - a forward-thinking international exercise physiologist and nutrition scientist - is the guest of todays episode, and we explore the physiological differences between male and female bodies and reveal how you can optimize yo...
Mar 10, 2023•47 min•Season 2Ep. 10
What are some steps that you can take to boost your immune system so that you can stop getting sick? What if you just started feeling some symptoms, are there specific supplements that will stop the sickness dead in its tracks? Dr. Chris Masterjohn is back on the podcast to outline his Ultimate Cold Prevention Protocol ! In this episode, Chris and Joe go through all of Chris’ prevention protocol - starting with what to do to strengthen your immune system, to your action plan when you first exper...
Mar 03, 2023•1 hr 16 min•Season 2Ep. 9
What supplements should I take to improve my hormones? Is there an optimal balance of estrogen and progesterone? Is prolactin an important hormone for men? Hormones are an extremely important part of optimizing your health, but the majority of people have no idea just how much of an impact they have on… well, everything . An estimated 30% of women experience hormone imbalances, which can cause mental health issues, weight issues, fertility, and much more. That is an absolutely insane number! So,...
Feb 25, 2023•1 hr 1 min•Season 2Ep. 8
