In this episode, Prof Chapman explains ovarian tissue cryopreservation, including who it is genuinely suitable for, why it remains largely an experimental fertility preservation technique, and its role for women facing urgent cancer treatment. He also answers a detailed question from a patient who has received a strong positive beta hCG result following embryo transfer. Prof Chapman discusses whether repeat blood tests are necessary, what healthy hCG progression should look like, the importance ...
Jun 18, 2026•5 min
In this episode, Prof Chapman explains how he approaches patients who have already spent tens of thousands of dollars on unsuccessful IVF treatment and are seeking a second opinion. He discusses the importance of reviewing previous cycles in detail, identifying anything that may have been missed, and tailoring a new treatment strategy to improve outcomes. Prof Chapman also highlights the often-overlooked role of the male partner in IVF success, including practical advice on sperm health, abstine...
Jun 16, 2026•4 min
In this episode, Prof Chapman answers a listener’s question about the success rates of IUI and IVF for a 37-year-old woman, explaining when IUI may be worth trying, why success rates drop after a few cycles, and how IVF can offer significantly higher cumulative pregnancy rates. He also shares practical advice on choosing the right fertility clinic, including what to look for in specialists, laboratory standards, clinic size, patient care, and nursing support—beyond simply comparing published suc...
Jun 10, 2026•9 min
In this episode, Prof Chapman explores how ethical concerns around IVF have evolved over the past four decades. He reflects on the early fears surrounding IVF, including concerns about interfering with nature and the long-term health of IVF-conceived children, and explains how decades of research have helped address many of those worries. Prof Chapman also shares his views on topics such as gender selection, genetic testing, and the likelihood of so-called “designer babies.” While he believes cu...
Jun 08, 2026•4 min
In this episode, Prof Chapman answers a listener’s question about whether frozen embryos should be thawed, genetically tested, and refrozen for PGT. He explains the small risk of embryo loss associated with the process, how PGT can significantly improve the chances of selecting a genetically normal embryo, and why the decision often depends on age, embryo numbers, and individual fertility goals. Prof Chapman also discusses the differences between testing day-one and day-five embryos, the impact ...
Jun 03, 2026•5 min
In this episode, Prof Chapman explains why human fertility is far less predictable than most people expect — and why even healthy couples may need up to 12 months to conceive naturally. He breaks down the real monthly chances of pregnancy, why IVF isn’t always the first answer, and the importance of patience when trying for a baby. Prof Chapman also shares a serious warning about anabolic steroids and gym supplements, revealing how they can dramatically reduce sperm production and sometimes caus...
May 27, 2026•9 min
In this episode, Prof Chapman explains how fertility specialists help couples decide between continuing to try naturally, moving to IUI, or starting IVF — without losing valuable time. He breaks down how age, fertility history, success rates, costs, and previous pelvic surgeries all influence treatment decisions. The discussion also covers IVF after endometriosis surgery, ectopic pregnancy, fibroids, and why fertility care must always be individualized. Explore the ‘Prof. Michael Chapman – The I...
May 25, 2026•8 min
In this episode, Prof Chapman explains the critical role mitochondrial health and energy metabolism play in egg competence and embryo development. He breaks down why egg quality declines with age, how chromosome errors happen, and the science behind popular fertility supplements like CoQ10, NADH, and DHEA. Prof Chapman also discusses emerging treatments such as PRP ovarian rejuvenation, why many therapies still lack strong clinical evidence, and what current research may hold for the future of f...
May 15, 2026•8 min
In this episode, Prof Chapman explains how he approaches patients seeking a second opinion after a disappointing IVF experience at another clinic. He discusses the emotional toll of failed fertility treatment, the importance of reviewing previous cycles in detail, and why individualized treatment strategies can sometimes make a difference. Prof Chapman also shares the realities of IVF success rates at different ages, offering honest, compassionate guidance to help patients understand their true ...
May 11, 2026•5 min
In this episode, Prof Chapman answers a common and important question from patients with low ovarian response: is it worth doing two IVF stimulation cycles close together to improve results? He explains why current evidence doesn’t strongly support repeated or back-to-back stimulation as a way to boost egg numbers, and highlights the role of natural biological variation from cycle to cycle—especially for women in their late 30s and early 40s. Prof Chapman also explores alternative approaches lik...
Apr 28, 2026•5 min
In this episode, Prof Chapman explains how AMH levels and antral follicle counts are used to assess ovarian reserve—and why they don’t tell the full story about egg quality or natural conception chances. He clarifies common misconceptions, especially for women trying to conceive in their 30s and 40s, and shares when it may be time to consider IVF. Prof Chapman also discusses the growing role of AI tools like ChatGPT in fertility research, highlighting their usefulness for general knowledge—but e...
Apr 23, 2026•6 min
In this episode, Prof Chapman explains ovarian reserve, how AMH testing works, and why low levels don’t always mean poor fertility. He highlights that egg quality depends on age—not AMH—and cautions against rushing into IVF based on misunderstood results. Explore the ‘Prof. Michael Chapman – The IVF Journey’ Facebook Page, your reliable destination for cutting-edge insights and guidance within the realm of In Vitro Fertilization (IVF). Don’t miss out on the IVF Journey podcast; stay informed wit...
Apr 20, 2026•7 min
In this episode, Prof Chapman breaks down the facts about fibroids—what they are, why they form, and how they impact fertility. He explains the different types of fibroids based on their location, highlighting why submucosal fibroids are the most significant when it comes to implantation and miscarriage risk. Prof Chapman also walks through how fibroids are diagnosed, when treatment is necessary, and why most fibroids are actually harmless. This episode offers clear, practical guidance to help y...
Apr 17, 2026•5 min
In this episode, Prof Chapman answers key questions from patients navigating their fertility journey—from what tests to take before starting IVF to how to interpret mosaic embryo results. He breaks down the science behind embryo genetics in simple terms, offering clarity on what mosaic embryos really mean and why they may not be as concerning as they seem. The discussion also explores when fresh vs frozen embryo transfers are appropriate, and why choosing the right fertility specialist is a cruc...
Apr 10, 2026•9 min
In this episode, Prof Chapman addresses a challenging case of repeated frozen embryo transfer (FET) failures and explores what truly matters before trying again. He discusses why immune therapies like steroids and Clexane may not be as effective as commonly believed, and highlights the importance of embryo quality—particularly genetic testing to rule out aneuploidy. Prof Chapman also shares emerging insights on progesterone optimization before transfer, the role of ultrasound-guided embryo place...
Apr 06, 2026•5 min
In this episode, Prof Chapman cuts through common misconceptions in fertility treatment explaining why a previous natural pregnancy doesn’t change the diagnostic process, what “euploid” and “aneuploid” embryos actually mean for IVF success, and why the popular belief that quality always trumps quantity when it comes to eggs is more nuanced than most patients realise. Explore the ‘Prof. Michael Chapman – The IVF Journey’ Facebook Page, your reliable destination for cutting-edge insights and guida...
Apr 03, 2026•5 min
In this episode, Prof Chapman breaks down recurrent miscarriage, including which baseline tests are truly worth doing, which findings actually change treatment, and which commonly suggested tests have weak evidence behind them. He explains the role of embryo chromosomal abnormalities, balanced translocation, uterine assessment, antiphospholipid syndrome, sperm DNA fragmentation, and when options like progesterone or IVF with genetic testing may be worth considering. Explore the ‘Prof. Michael Ch...
Mar 30, 2026•9 min
In this episode, Prof Chapman answers two important IVF questions: whether an Ovidrel trigger can cause a rise in TSH, and why the same patient can have very different ovarian responses in back-to-back IVF cycles. He explains the biology behind temporary thyroid changes during treatment, the role of rising estrogen, and why ovarian response is never exactly the same from one cycle to the next. Prof Chapman also explores the concept of follicle “waves,” how random-start IVF works, and what doctor...
Mar 25, 2026•5 min
In this episode, Prof Chapman explains why severe endometriosis can create a difficult fertility dilemma, especially when ovarian cysts need surgical removal. He shares how surgery for endometriomas, while sometimes necessary, can reduce ovarian reserve by damaging healthy ovarian tissue. Prof Chapman discusses why many fertility specialists now recommend doing IVF first, freezing embryos before surgery, and then transferring them later into a healthier uterine environment. He also covers when l...
Mar 23, 2026•4 min
In this episode, Prof Chapman breaks down why endometriosis is one of the most underdiagnosed causes of infertility — affecting up to 30% of infertile women, often with no symptoms at all. He explains exactly how it damages fertility, what to watch for, and why getting the right diagnosis early can make all the difference. Explore the ‘Prof. Michael Chapman – The IVF Journey’ Facebook Page, your reliable destination for cutting-edge insights and guidance within the realm of In Vitro Fertilizatio...
Mar 19, 2026•7 min
In this episode, Prof Chapman cuts through the noise to reveal what’s truly moved the needle in IVF over the past decade — and it’s not what most patients expect. From the quiet revolution happening in fertility lab culture mediums and incubators, to the game-changing shift in embryo freezing techniques, Prof Chapman shares the under-the-radar advances that have pushed pregnancy rates from 25% to 40%. He also tackles the growing questions around GLP-1 medications like Ozempic in fertility treatm...
Mar 02, 2026•6 min
In this episode, Prof Chapman explains why selecting the right fertility specialist can significantly influence your IVF journey and outcomes. Responding to questions about failed protocols, limited embryos in storage, and embryo grading, he breaks down what classifications like “3BB” really mean and how treatment strategies can be refined to improve your chances. Drawing on over four decades of experience, Prof Chapman discusses the role of clinical intuition alongside data, the importance of s...
Feb 23, 2026•7 min
In this episode, Prof Chapman answers a listener’s question about recovering from surgery before restarting IVF, and then opens up about one of the most challenging parts of his work which is the difficult conversations that follow failed embryo transfers. He explains why even in women under 38, the success rate per transfer is only around 40%, and why that still leaves so many patients searching for answers. Prof Chapman discusses the role of embryo genetics, why testing can improve outcomes, a...
Feb 20, 2026•9 min
In this episode, Prof Chapman walks through the clinical pathway for couples diagnosed with unexplained infertility. He explains tubal testing, the temporary fertility boost after flushing the tubes, when to keep trying naturally, and when to move forward to IUI or IVF. Clear, step-by-step guidance to help you feel confident about your next move. Explore the ‘Prof. Michael Chapman – The IVF Journey’ Facebook Page, your reliable destination for cutting-edge insights and guidance within the realm ...
Feb 16, 2026•7 min
In this episode, Prof Chapman breaks down one of the most common and confronting questions patients ask: “How much is IVF really going to cost?” He explains why IVF prices vary so widely across Australia, unpacking the difference between low-cost and premium services, and what those differences mean for patient care, laboratory standards, genetic testing, staffing, and outcomes. Prof Chapman also puts IVF costs into a broader life perspective—comparing treatment expenses with the long-term costs...
Feb 12, 2026•7 min
In this episode, Prof Chapman explains what poor fertilisation means in IVF and why it happens, despite everything appearing “normal.” He walks through expected fertilisation rates, how labs rule out technical issues, and why egg quality, age, sperm health, and DNA fragmentation are the most common underlying factors. Prof Chapman also outlines practical adjustments for future cycles, including the role of ICSI, timing changes, and realistic expectations after a disappointing fertilisation resul...
Feb 09, 2026•10 min
In this episode, Prof Chapman explains why there is currently no proven treatment that can reliably increase egg numbers or embryo yield in an IVF cycle, despite bold claims about supplements and therapies. He unpacks the limits of current science, addresses popular compounds like NMN, and emphasizes why lifestyle factors, realistic expectations, expert care, and emotional support matter far more than chasing unproven solutions. The discussion also explores what truly separates an excellent IVF ...
Jan 27, 2026•7 min
In this episode, Prof Chapman explains why a healthy diet and folic acid matter and why most advertised supplements don’t improve egg or sperm quality despite bold claims online. He also discusses when donor sperm or donor eggs become a practical next step in fertility treatment, outlining the medical realities, key decision points, and how specialists support patients through what can be an emotionally complex choice. Explore the ‘Prof. Michael Chapman – The IVF Journey’ Facebook Page, your rel...
Jan 23, 2026•5 min
In this episode, Prof Chapman explains why extensive immune testing in IVF almost always finds something “abnormal” and why that doesn’t mean treatment will help. He breaks down the science behind immune markers, the lack of proven benefit from immune therapies, and how patients can be misled by results that sound concerning but change nothing clinically. Explore the ‘Prof. Michael Chapman – The IVF Journey’ Facebook Page, your reliable destination for cutting-edge insights and guidance within t...
Jan 20, 2026•8 min
In this episode, Prof Chapman draws on nearly 40 years of IVF experience to unpack the growing use of so-called IVF “add-ons” or adjuvants. He explains why many treatments offered after failed cycles—such as CoQ10, DHEA, and testosterone—are not supported by strong scientific evidence, despite their popularity. Prof Chapman also clarifies real IVF success rates over multiple cycles, challenges misleading claims, and offers a grounded perspective on where hope truly comes from in fertility treatm...
Jan 16, 2026•8 min
