IN THIS EPISODE OF THE HUMAN UPGRADE™... Dave talks with Mandy Pennington, a longtime Upgrade Collective member and dedicated hacker who has used biohacking techniques successfully to upgrade her body and mind. Mandy is a sharp and curious person who wants to learn more about how to apply the topics in Smarter Not Harder to her spirituality, quantum energy, spirit guides, and leading a purpose-driven life that feels right for her soul. An important aspect of this episode is focussed on how Mandy...
Feb 14, 2023•33 min•Ep. 1021
IN THIS EPISODE OF THE HUMAN UPGRADE™... I am honored and grateful to bring you a conversation that I recorded in person with Gurudev Sri Sri Ravi Shankar at the Art of Living Center in Los Angeles. Gurudev Sri Sri Ravi Shankar is a leader of an international movement with more than 50 million followers who do breathwork every single morning. He has worked for 40 years as a global ambassador for peace at the highest levels. I did his breathwork exercises every morning without fail fo...
Feb 09, 2023•35 min•Ep. 1020
IN THIS EPISODE OF THE HUMAN UPGRADE™... I do something different. Over the past 1000+ episodes, I have spent a lot of time talking and learning from my guests, but I have heard over and over that you would like to hear more from me about what I am doing, trying and thinking. Well, that can be awkward to do sitting alone in front of a microphone. A while ago, Danica Patrick interviewed me and it is one of my favorite podcast interviews ever. Danica did a great job of digging into why I do ...
Feb 07, 2023•1 hr 27 min•Ep. 1019
H.V.M.N. sponsored this episode. IN THIS “UPGRADE SPOTLIGHT” EPISODE OF THE HUMAN UPGRADE ™…Metabolic biochemist Latt Mansor, Ph.D., joins the show from H.V.M.N . (Health Via Modern Nutrition), where he leads research for the company. He’s an expert in metabolism who consults with elite sport, military, clinical and research organizations. As a key biomarker of metabolic health, ketones are a source of fuel for your brain and body. They’re different from glucose and fat—and more effi...
Feb 04, 2023•45 min•Ep. 1018
IN THIS EPISODE OF THE HUMAN UPGRADE™ … Dr. Kelly Brogan shares why her views often go against conventional thinking—on topics from pharmaceuticals to sex to pole dancing to relationship compatibility. She's a psychiatrist who specializes in psychosomatic medicine and integrative holistic medicine. Her root-cause resolution approach to psychiatric syndromes and symptoms coupled with other support techniques helps women reclaim their divine feminine power. I previously talk...
Feb 03, 2023•1 hr 22 min•Ep. 1017
IN THIS EPISODE OF THE HUMAN UPGRADE™… you’re going to learn how to work with your own biology, adapt to adversity, and get resilient AF. Doctor, educator and entrepreneur Dr. Molly Maloof joins the show in person in Austin, Texas, to talk about her debut book, “ The Spark Factor: The Secret to Supercharging Energy, Becoming Resilient, and Feeling Better Than Ever .” For women biohackers, it’s all about energy—and hormones. “Cycles are exactly why the way guys biohack doesn’t al...
Feb 01, 2023•59 min•Ep. 1016
IN THIS EPISODE OF THE HUMAN UPGRADE™… board-certified OB/GYN and “menopause warrior” Mary Claire Haver, M.D. , joins the show to give women a toolkit to manage what comes before, during and after menopause. She explains the science of women’s hormones, physiology and brain during the menopausal transition. She breaks down the studies, risks, and age timing of Hormone Replacement Therapy. She gives you information you can use to both help yourself and ask for help from medical pr...
Jan 27, 2023•56 min•Ep. 1015
IN THIS EPISODE OF THE HUMAN UPGRADE™… Susanna Soeberg, Ph.D., a Danish researcher, international scientist and expert in cold and heat therapy for health and performance, explains how you can harness the massive benefits of cold water immersion (winter swimming), sauna, breathing, and your metabolism. When it comes to biohacking, a few things rise to the top and make a pretty big difference in your body and brain. Through her research, Susanna discovered the minimum threshold of cold and h...
Jan 25, 2023•1 hr 1 min•Ep. 1014
Leela Quantum Tech sponsored this episode. IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll learn why energy frequencies have such a powerful influence on human physiology. Skeptics take note: science backs this up. Philipp Samor Von Holtzendorff-Fehling introduced quantum energy on episode #809 and its benefits on body function, cellular voltage and chakra energy. He returns to the show with exciting new research that further validates the power of this energy an...
Jan 20, 2023•1 hr 6 min•Ep. 1013
IN THIS EPISODE OF THE HUMAN UPGRADE™… Harvard psychiatrist, researcher and assistant professor Christopher Palmer, M.D., introduces a bold new premise about the root cause of mental illness based on decades of research. Dr. Palmer integrated existing theories and research into one unifying theory—the brain energy theory of mental illness that’s rooted in your metabolism. Through his research, he initially pioneered using a medical ketogenic diet to treat psychiatric disorders. In th...
Jan 18, 2023•55 min•Ep. 1012
IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll meet Gloria Mark, Ph.D., who studies how digital media impacts people's lives. Her research specifically covers how attention is affected by, and has changed, with the rise of the digital age. She’s found that attention span now averages 47 seconds on a screen—and even that’s shrinking. As a Chancellor’s Professor of Informatics at the University of California-Irvine researching human-computer interaction, Gloria examines how people handle multitaski...
Jan 13, 2023•1 hr 3 min•Ep. 1011
IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll meet Robert Waldinger, M.D., who leads an extraordinary scientific study on happiness that’s still going strong after eight decades. The study set out to understand human health by what made people thrive . Since 1938, the Harvard Study of Adult Development has tracked two groups of men and their families with the goal of discovering what really makes for a good life. Along the way, thousands of questions were asked, and hundreds of ...
Jan 10, 2023•1 hr 13 min•Ep. 1010
Neurohacker Collective sponsored this episode. IN THIS "UPGRADE SPOTLIGHT" EPISODE OF THE HUMAN UPGRADE ™… you’re going to learn about the zombie cells taking up valuable space in your body and how you can clear them out with senolytics. When these zombie cells accumulate (formally called senescent cells), they negatively impact how you age. You may experience symptoms like joint discomfort, low mental and physical energy, poor metabolic health, and diminished muscular response when you wo...
Jan 07, 2023•32 min•Ep. 1009
IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... the new year starts off with a Legacy Upgrade conversation between Dave Asprey and Dr. Andrew Weil recorded live at True Food Kitchen in Phoenix, Arizona. Dr. Weil’s an internationally known pioneer and leader in integrative medicine. He’s also a Harvard-trained botanist and medical doctor recognized worldwide for his views on living a healthy lifestyle, his philosophy of healthy aging, and his critique of the future of med...
Jan 06, 2023•52 min•Ep. 1008
IN THIS EPISODE OF THE HUMAN UPGRADE™… Humble The Poet joins the show to talk about a unique perspective on love. You’ll learn: what “real” love means (hint: it’s not found or earned) and how to recognize it in your life. how to shift away from a mindset of earning more, achieving more, and gaining more attention so you can clear pathways for love to enter and flourish in your life how to ditch restrictive “resolutions” (that fail more often than they succeed) and instead set intentions th...
Jan 04, 2023•1 hr 2 min•Ep. 1007
IN THIS “BEST OF” EPISODE OF THE HUMAN UPGRADE™… … Ari Whitten, Ph.D. (Cand.), CES, PES , explains how to double your energy through improved resilience, cell defense, nutrition and supplementation. In his newest book, “ EAT FOR ENERGY: How to Beat Fatigue, Supercharge Your Mitochondria, and Unlock All-Day Energy ,” Ari explains that 5.4 million adults in the U.S. have been diagnosed with chronic fatigue syndrome (the most severe case of fatig...
Dec 30, 2022•1 hr 2 min
IN THIS “BEST OF” EPISODE OF THE HUMAN UPGRADE™… … Steven Gundry, M.D. , explains that ketones aren’t the fat-burning molecules you think they are. Ketones actually work to enhance health, weight loss, and longevity by acting as signaling molecules that stimulate your mitochondria. A cellular process known as “mitochondrial uncoupling” happens. He debunks common myths about keto in his newest book, “ Unlocking the Keto Code: The Revolutionary New Science of Keto T...
Dec 28, 2022•1 hr 29 min
IN THIS “BEST OF” EPISODE OF THE HUMAN UPGRADE™ … natural vision expert Claudia Muehlenweg explains how you can take better care of your eyes and improve your vision. Her work is based in the Bates Method . She focuses on finding the root cause of blurry vision instead of using symptomatic treatments like glasses, contacts or surgery that actually can make eyesight worse in the long term. For nearly 15 years, Claudia’s taught eyesight improvement for presbyopia,...
Dec 23, 2022•1 hr 23 min
In this Episode of The Human Upgrade™ … Dave talks with Rachelle Copeland about putting her energy into healing facial injuries and building new tissues—starting with the central nervous system. Rachelle experienced an accident that injured her face, teeth, nerves and jaw. She wants to heal quickly and avoid scarring and long-term damage while also managing the accompanying emotional trauma. This intervention looks at ways to heal and recover both internally and externally, covering suggestions ...
Dec 21, 2022•29 min•Ep. 1006
Viome sponsored this episode. IN THIS EPISODE OF THE HUMAN UPGRADE™… entrepreneur and philanthropist Naveen Jain joins the show in person at the Beverly Hilton to talk about new developments in the human biome—particularly the oral microbiome. Turns out, there may be more density in your gut microbiome, but there’s more diversity in your oral microbiome. Naveen’s company, Viome , built an AI-driven platform that analyzes the interaction between food, you...
Dec 16, 2022•1 hr 4 min•Ep. 1005
Pendulum sponsored this episode. IN THIS EPISODE OF THE HUMAN UPGRADE™ …molecular biologist and biochemist Colleen Cutcliffe, Ph.D., returns to the show with brand new science about your gut. She’s a regular guest because she and her team at Pendulum continue to uncover innovative ways to improve your gut health, your metabolism, your immune system, how your brain works and how long you live. This time, Akkermansia’s back in the spotlight, with more than 300 new studies sh...
Dec 13, 2022•44 min•Ep. 1004
IN THIS EPISODE OF THE HUMAN UPGRADE™ … you’ll find out that kids are killing themselves more often and at younger ages. Suicide prevention expert Dr. Mark Goulston joins the show to discuss the very real and very urgent topics of youth mental health and suicide—from pre-teens to teens to young adults. These issues concern everyone , not only families, educators or professionals who connect with young people. Here’s why: Suicide shows up in the top three causes of death in young peopl...
Dec 09, 2022•1 hr 1 min•Ep. 1003
IN THIS EPISODE OF THE HUMAN UPGRADE™ … you’ll learn about a new holistic framework for self-healing and how to heal yourself with prompts, tools and actionable tips. Using the tenants of holistic psychology, Nicole LePera, Ph.D., created a different way to reach people and equip them with the tools necessary to heal themselves. Holistic psychology focuses on the mind, body, and soul in the service of rebalancing the body and nervous system and healing unresolved emotional wounds. ...
Dec 06, 2022•49 min•Ep. 1002
IN THIS EPISODE OF THE HUMAN UPGRADE ™… Dan Buettner joins the show to talk about the origins and food foundations of Blue Zones. He discusses how they were discovered, what makes them different, and what’s changed for people living there over the past few decades. And the big question—is it still possible to live to 100? Dan, an explorer, National Geographic Fellow, award-winning journalist and producer, and photographer, has studied and written extensively about the five places in ...
Dec 02, 2022•50 min•Ep. 1001
( ZBiotics sponsored this episode.) IN THIS EPISODE OF THE HUMAN UPGRADE ™… you'll find out how to counter the sometimes rough morning after you have alcohol. The key is a new genetically engineered pre-alcohol probiotic drink. Great timing as you head into the holiday season of celebrations. Zack Abbott, CEO & co-founder of ZBiotics , joins this 1,000th episode of the podcast to talk about new discoveries in alcohol metabolism, genetic engineering and GMOs (used in a good wa...
Nov 29, 2022•56 min•Ep. 1000
In this Episode of The Human Upgrade™... Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month. Sperm that swim together increase their chances of fertilization Late-night eating is worse than you thought Metabolic markers can be measured through your sweat Eye movements during REM sleep could delete unwanted memories EPISODE SPONSOR: Humic & fulvic minerals provide critical cel...
Nov 25, 2022•8 min
Timeline Nutrition sponsored this podcast. IN THIS EPISODE OF THE HUMAN UPGRADE ™… immunologist Anurag Singh, M.D., Ph.D., MBA, Chief Medical Officer at Amazentis, joins the show to talk about urolithin A’s connection between inflammation, aging and your mitochondria. Urolithin A activates mitophagy and renews your mitochondria. “It takes all the cellular garbage that has been accumulating over the aging process,” Dr. Singh explains. “It revs it up, so it recharges. A...
Nov 22, 2022•50 min•Ep. 999
IN THIS EPISODE OF THE HUMAN UPGRADE ™… Robynne Chutkan, M.D., joins the show to talk about a topic that’s foundational to biohacking—resilience. More specifically, resilience that starts in the gut. You’ll learn: how your microbiome continually evolves and why that matters to the state of your gut and body functions. how to strengthen the antiviral defenses located in your gut. why your body’s own ability “to resist, heal, and recover from viruses is vastly superior” to pharmaceuticals. wh...
Nov 18, 2022•1 hr 18 min•Ep. 998
Eight Sleep sponsored this podcast. IN THIS EPISODE OF THE HUMAN UPGRADE ™… you’ll learn about the intimate relationship between performance and sleep and how you can hack both with a combination of tech and lifestyle. Matteo Franceschetti joins the show to talk about high performance—something he experienced in athletics, business and life. He was a competitive athlete in his native Italy and a race car driver across Europe. He started two clean-tech companies on two continents...
Nov 15, 2022•49 min•Ep. 997
BiOptimizers sponsored this podcast. IN THIS EPISODE OF THE HUMAN UPGRADE ™… you're going to get into bed with the topic of sleep. Pretty much everyone’s favorite. In this conversation, veteran biohacker and BiOptimers co-founder Matt Gallant returns to the show with some straight talk about how to get more and better sleep. He’s spent the big bucks—about $50K he estimates—exploring, experimenting and upgrading his own sleep. He's sharing what he now knows so you can create a sl...
Nov 11, 2022•1 hr 9 min•Ep. 996
