Computers are everywhere and humans are engaging with them in nearly everything they do. Knowing this, the question becomes: How do we design a world around us so that technology makes life better, not worse? James Landay, an expert in human-computer interaction, says the key to thoughtfully integrating humans with digital technology is to put people first. This perspective draws on a philosophy known as human-centered or user-centered design. Within this approach, the first priority is to under...
Jul 19, 2019•28 min•Ep. 82
Biomedical data scientist Sylvia Plevritis is an expert in computational modeling of cancer risk and treatment options hidden in the remarkable quantity of data available today. Rarely is a tumor made up of a single mutation, she says, but more commonly of a mix of different mutations. Such heterogenous tumors may require complex combinations of drugs to produce the most effective treatments. That’s where computers can help. Using mathematical simulations, Plevritis is helping patients and their...
Jul 19, 2019•28 min•Ep. 86
Political scientist Jeremy Weinstein has worked at both the White House and the United Nations. In both jobs, he encountered the ethical and policy concerns that new technologies can present to policymakers. As one example, he points to the fierce debate between Apple and national security experts over end-to-end encryption and the challenges investigators faced in accessing data on the iPhones of the perpetrators of a terrorist attack in San Bernardino in 2015. He wants universities, like Stanf...
Jul 12, 2019•28 min•Ep. 78
Once avoidance was the only answer, but a leading allergist says that advances in desensitizing allergies are challenging common convention. Food allergy expert Kari Nadeau, MD, PhD, says that as many as one in ten adults in the U.S. has a food allergy, many without knowing it. With consequences that range from mild to serious (including lethal anaphylaxis), it is imperative that medical scientists become better adept at spotting food allergies and ultimately at helping patients cope with allerg...
Jun 28, 2019•29 min
Can we reap the benefits of artificial intelligence while also protecting our personal information? From scheduling appointments to setting the thermostat to ordering pizza, virtual assistants are growing more commonplace by the day. Stanford professor Monica Lam says they will only become more entrenched as their capabilities grow and their voice-recognition skills become more accurate. Such developments are welcomed by many who rely upon Alexa and Siri and other virtual assistants. But it is a...
Jun 04, 2019•28 min•Ep. 80
In-depth statistical analyses show time and again that subtle, unconscious bias is pervasive in the American justice system. The bigger question, however, is what to do about it? Sharad Goel is an expert in computational social science – that is, using computers and data to examine and address policy issues. He says unconscious bias is subtle but entrenched in American life, and nowhere are the consequences more concerning than in criminal justice. Goel has analyzed hundreds of millions of crime...
May 31, 2019•28 min•Ep. 77
When Stanford’s Paul Yock was a young interventional cardiologist, he was frustrated by the complex, two-person process required to deliver life-saving stents. So, he invented a better way. His Rapid Exchange stenting and balloon angioplasty system, one of several inventions Yock is known for internationally, can be managed by just a single operator, making procedures like stent placement faster and safer. Yock is a man of many talents. He is a doctor, a professor of bioengineering and of mechan...
May 06, 2019•28 min•Ep. 81
Margaret Brandeau may carry a business card that reads Professor of Management Science and Engineering, but her expertise is in using complex systems models to solve challenges in public health policy. For instance, she recently created a sophisticated computer model of the national opioid crisis, which led her to the stark –and surprising – conclusion that it may take a short-term rise in deaths to ultimately reduce them. She didn’t come to that conclusion lightly, but made no less than 10 mode...
May 06, 2019•28 min•Ep. 79
By last count, there are 5,000 genetic diseases in the human body. A few are merely annoying, but far more are devastating and without cure. In the last decade, much popular attention has been focused on the potential for stem cells and gene therapies to cure these once-intractable diseases. While the promise is clear, Tony Oro cautions patience. Oro is a dermatologist and associate director of the Center for Definitive and Curative Medicine at Stanford. He is a leading expert in the scientific ...
Apr 22, 2019•29 min•Ep. 75
Brain cancers are known to be elusive and clever killers, but Michelle Monje, associate professor of neurology and neurological sciences, is helping to find new treatments through a better understanding of how healthy brain cells develop and how cancers often hijack those very same processes in order to grow themselves. Monje says that the last decade has seen tremendous progress in our understanding of how cancers thrive and in the development of new drugs and therapies to kill the killers. Unf...
Apr 22, 2019•28 min•Ep. 74
The current process for diagnosing autism requires no less than 10 hours of intensive doctor-to-patient observation. It is expensive and time-consuming, says autism expert Dennis Wall, an associate professor of pediatrics and of biomedical data science at Stanford. Wall is developing new ways to tackle the problem. He says advances in machine learning, a branch of artificial intelligence focused on training computers to perform important medical tasks, stand to shake up the field. He’s developin...
Apr 03, 2019•28 min•Ep. 76
Mechanical engineer Xiaolin Zheng really likes to burn things, but she is more like a modern-day Prometheus than a pyromaniac. She uses combustion to create minute nanoparticles of various metal oxides that have many practical and valuable uses in today’s world. For instance, she has created nanoparticles that can turn water into hydrogen peroxide using only energy from the sun. Hydrogen peroxide is a powerful disinfectant that kills microbes and removes other pollutants from water. Zheng imagin...
Mar 12, 2019•28 min•Ep. 73
In safety engineering, ergonomic differences between men and women are important. Conventional seat belts do not fit pregnant women properly and motor vehicle crashes are the leading cause of fetal death related to maternal trauma. Analyses of sex differences have led to the development of pregnant crash test dummies that enhance safety in automobile testing and design. In medicine, osteoporosis has been conceptualized primarily as a women's disease, yet after a certain age men account for nearl...
Mar 06, 2019•28 min•Ep. 72
Stanford radiation oncologist, Billy Loo, says that a new generation of radiation therapy technology called PHASER will be so fast that it can even compensate for the patient moving during treatment. High-energy X-rays will be fired so quickly, like a flash photograph, that motion is frozen and radiation can be more precisely focused on tumors. His research team is also finding that such ultra-fast “FLASH” radiation kills cancer cells through new biological mechanisms while causing less damage t...
Mar 05, 2019•28 min•Ep. 71
Carlos Bustamante is an expert in genomics—the study of genetic variation and its effects on the living world. He says genomics holds tremendous promise but, so far, virtually all sequenced DNA comes from European blood lines and this presents a problem. Without greater diversity in the genomic data that is collected, he notes that we cannot fully reap the benefits of this knowledge, particularly in areas such as healthcare. "Genomics is the new oil," Bustamante says, of the opportunit...
Feb 14, 2019•28 min•Ep. 68
Why do well-off public schools often demand that parents supplement school programs with personal contributions? Why do many rare diseases receive the lion’s share of donor attention and money? Is basic science being driven by the whims of big donors? These are questions that keep Stanford political philosopher Rob Reich up at night. Reich says that philanthropy is at an ethical crossroads in which the heart often leads the head in determining which causes get showered with money while other, pe...
Feb 11, 2019•28 min•Ep. 70
Of the many nations that have implemented some measure of digital democracy, none perhaps has had more success than Estonia. Toomas Ilves, a Distinguished Visiting Fellow at the Hoover Institution, would know: He served as president of the Baltic state for two terms. Ilves says that all Estonians have verifiable digital identities and they use them to vote, sign legal documents, order prescription medication, file taxes and more online. Estonian digitization began with schools and banking in the...
Feb 04, 2019•28 min•Ep. 69
In hospitals across the world, the unmet need for end-of-life palliative care threatens to overwhelm the few doctors who are equipped to adequately provide counseling that can help patients die on their own terms. There are just too many patients and too few doctors. Stanford’s Nigam Shah, an expert in medical informatics, says that such scenarios may soon become a thing of the past. Artificial intelligence, founded on tens-of-thousands of data points gathered from millions of patients, is flipp...
Dec 20, 2018•28 min•Ep. 63
The worlds of academic economics and ride sharing are not so far removed – just ask Stanford labor economist Paul Oyer. When Oyer wanted to study the gig economy, he didn’t do it from afar; he became an Uber driver. Oyer says lessons from the gig economy hold deep lessons for the job market for more traditional jobs. Uber’s surge pricing, for instance, is more than a payment structure – it entices Uber drivers to work odd hours or at times of peak demand. He says Uber is constantly reworking its...
Dec 20, 2018•28 min•Ep. 62
It’s nothing we haven’t already heard – the news you read is being shaped by the ubiquitous presence of social media. So-called “fake news” spread by bots and social media may continue to influence American elections and, ultimately, democracy. Alex Stamos, the former chief security officer at Facebook and an adjunct professor with Stanford’s Freeman Spogli Institute for International Studies, explained at a recent live taping of “The Future of Everything” that the emergence of social media has ...
Dec 20, 2018•32 min•Ep. 65
The next job search you conduct will likely be shaped by artificial intelligence. In the age of LinkedIn and Monster.com, job hunters can count on their resumes being screened by non-human intelligence. So what does this mean for the future of hiring? At a recent live taping of the Stanford School of Engineering podcast “The Future of Everything,” Adina Sterling, an assistant professor of organizational behavior at Stanford Graduate School of Business who studies labor markets, said that roughly...
Dec 20, 2018•24 min•Ep. 64
Earthquakes come in species, says Greg Beroza, professor of geophysics at Stanford and an expert in seismology. There are, of course, the well-known sudden shocks, but there are also “slow earthquakes” that transpire imperceptibly in contrast to the obvious temblors, but which can measure 7 on the Richter Scale or more — a major quake by any standard. Beroza knows about slow and other species of earthquakes because of a recent explosion in the availability of seismic data recorded by an expansiv...
Nov 17, 2018•29 min•Ep. 66
Like clockwork, every time a large natural disaster hits and wipes out billions in built infrastructure, public officials, developers and private citizens cry, “never again.” And every time, equally like clockwork, very little gets done, says Stanford civil engineer Anne Kiremidjian, one of the world’s foremost authorities on constructing buildings that can withstand major natural disasters. She says there are technologies available that could move us toward stronger, safer buildings, but a lack...
Nov 17, 2018•27 min•Ep. 67
While Alzheimer’s disease has cut short too many lives and devastated more families than can be counted, its root causes and effective treatments have eluded researchers for decades. But, says Stanford bioengineer Annelise Barron, new science indicates that many Alzheimer’s cases are coincident with viral or bacterial infections in the brain, pointing to possible new approaches to treatment or prevention. Barron says that one human protein in particular, LL-37 — which she refers to as a “Ninja p...
Oct 24, 2018•29 min•Ep. 59
Riana Pfefferkorn is a digital security expert and Cryptography Fellow at the Stanford Center for Internet and Society. She says that we are living in the “Golden Age of Surveillance,” in which the growing ubiquity of data-rich smart devices has produced a fundamental tension between the rights of users to protect their personal data and the needs of law enforcement to investigate or prevent serious crimes. She says draft legislation in Australia could have major privacy and security implication...
Sep 22, 2018•28 min•Ep. 57
While climate change is likely to bring rising sea levels, more frequent and stronger storms, as well as vanishing glaciers and coral reefs, experts say there are other lurking impacts that could have a more lasting effect on human behavior and health. Marshall Burke is a professor of Earth System Science and a fellow at Stanford’s Freeman Spogli Institute for International Studies who says that recent research shows rising global temperatures will lead to more wars, higher crime rates and great...
Sep 22, 2018•28 min•Ep. 58
Professor David Magnus, director of the Stanford Center for Biomedical Ethics, says that artificial intelligence and machine learning are reshaping the landscape of medical care, but the underlying algorithms and the overarching challenges of how to employ the data are begetting new and vexing ethical questions. Magnus explains that concerns begin with who designs, builds and pays for the algorithms and whether the ultimate goal of AI is better outcomes for patients, or better bottom lines for p...
Sep 08, 2018•29 min
While well-known mapping apps have transformed the daily commute through better information, Stanford electrical engineer Balaji Prabhakar is exploring ways to digitally incentivize people to improve their driving habits. He calls it “nudging,” and says that small shifts in commute times — just 20 minutes earlier or later — can make a considerable impact on the day’s congestion in highly trafficked urban areas, like San Francisco. A few years ago, Prabhakar made headlines with a Stanford-only st...
Sep 08, 2018•27 min
Am I saving enough for retirement? Will I outlive my money? Can I count on Social Security? These are but a few of the nagging questions most every American grapples with when contemplating retirement. Gopi Shah Goda of the Stanford Institute for Economic Policy Research (SIEPR) says that the migration from once ubiquitous and relatively secure pension programs to today’s self-directed retirement plans are producing anxiety and indecision in retirement planning precisely at the worst time, and i...
Jul 28, 2018•27 min•Ep. 53
While cryptocurrencies Bitcoin and Ethereum gather the lion’s share of headlines, few know that these “killer apps” are just the first generation of products based on a relatively new ledger-like technology called blockchain. Founder of the Center for Blockchain Research at Stanford, Dan Boneh says that blockchain is generating a swell of excitement among coders and computer scientists not witnessed since the earliest days of the internet. While the true killer apps are still to come, Boneh says...
Jul 28, 2018•29 min•Ep. 54
