Send us Fan Mail In this episode, Dr. Mark Holthouse joins Dr. Jaclyn Smeaton and DUTCH founder Mark Newman to take a closer look at a recent peer-reviewed publication from Precision Analytical, Inc. in Frontiers in Reproductive Health , examining how different testing methods hold up when it comes to monitoring male TRT in clinical practice. Their discussion also covers: Common misconceptions about how creams and gels show up in saliva testing and why the numbers can be misleading What the clin...
May 26, 2026•1 hr 8 min•Ep. 155
Send us Fan Mail In this episode, Dr. Jaclyn Smeaton discusses Hashimoto’s thyroiditis with Inna Topiler, a board-certified clinical nutritionist who shares her personal experience and health journey with Hashimoto’s. Their discussion also covers: Why standard thyroid testing is insufficient The four main triggers of immune confusion in Hashimoto’s, including stress, infections, toxins, and food sensitivities The impact of dysregulated cortisol on thyroid function How cortisol patterns on the DU...
May 19, 2026•58 min•Ep. 154
Send us Fan Mail Join us for this episode with Dr. Jenn Simmons, an integrative breast surgeon and oncologist, alongside host Dr. Jaclyn Smeaton and DUTCH founder Mark Newman. This conversation deepens the discussion from a previous episode on hormones and breast cancer risk, challenging widely held clinical assumptions rooted in the Women's Health Initiative (WHI) study. This episode also explores: The critical distinction between progestins and progesterone The role of metabolic dysfunction in...
May 12, 2026•1 hr 9 min•Ep. 153
Send us Fan Mail In this episode, Dr. Asare Christian and Dr. Jaclyn Smeaton discuss female longevity and health span. Dr. Christian brings his unique perspective as a former pain specialist who discovered that many of the chronic conditions he was treating were rooted in hormone imbalance. This episode also highlights: · Three main factors that can contribute to women living longer · The protective qualities of estrogen as well as the effects of its decline during perimenopause · The importance...
May 05, 2026•54 min•Ep. 152
Send us Fan Mail In this episode, Dr. Jaclyn Smeaton and Dr. Donielle Wilson discuss Dr. Donielle’s clinical philosophy, research findings, and personal journey around understanding and treating stress. Their discussion also covers: The stress response and how it’s highly individualized, shaped by genetics, and impacted by prior stress exposure How standard cortisol testing misses most of the cortisol picture Chronic stress and its cascade to multiple body systems, including the reproductive sys...
Apr 28, 2026•1 hr 3 min•Ep. 151
Send us Fan Mail In this insightful episode, Dr. Heather Sandison and Dr. Jaclyn Smeaton discuss the root causes of cognitive decline and Alzheimer's, how a naturopathic approach differs from conventional medicine, and practical strategies for brain health at any age. This episode also highlights: The six drivers of cognitive decline The impact of hormones, especially the steep drop in estrogen at menopause How infections like Lyme disease, shingles, and COVID-19 can be linked to cognitive decli...
Apr 21, 2026•59 min•Ep. 150
Send us Fan Mail In this episode, Dr. Jaclyn Smeaton sits down with Dr. Bryant Esquejo, ND to unpack acne through a functional medicine lens, moving far beyond the surface to explore what’s really happening inside the body. Dr. Esquejo and Dr. Smeaton also discuss: Acne as not just a skin condition, but a reflection of imbalances involving hormones, blood sugar, inflammation, and the gut microbiome The science behind acne development, from bacterial activity and oil production to deeper drivers ...
Apr 14, 2026•48 min•Ep. 149
Send us Fan Mail In this episode, Dr. Jaclyn Smeaton and DUTCH Founder Mark Newman discuss a case study published in Integrative Medicine: A Clinician’s Journal in which Mark himself was the patient. The case covers the step-by-step hormonal and metabolic effects of using HCG to boost endogenous testosterone, revealing how increasing testosterone can cascade into elevated estrogen, impaired estrogen clearance, and strained methylation capacity. Their conversation also highlights: The benefits of...
Apr 07, 2026•52 min•Ep. 148
Send us Fan Mail Join Dr. Allison Smith and Dr. Jaclyn Smeaton for this episode as they share expert insights into how hormones, the HPA axis, and lifestyle factors influence immune health, injury risk, sleep, and overall well-being during perimenopause and menopause. Dr. Smeaton and Dr. Smith also discuss: The relationship between hormonal changes, stress, and inflammation How cortisol and estrogen can impact sleep quality and inflammation in perimenopausal women Patterns seen on DUTCH tests in...
Mar 31, 2026•53 min•Ep. 147
Send us Fan Mail In this episode, Dr. Alan Bauman and Dr. Jaclyn Smeaton discuss the complexities of hair restoration, particularly focusing on menopausal hair loss in women. This discussion also explores: Understanding female pattern hair loss Emotional and hormonal factors affecting hair health Innovative therapies that can aid in hair restoration, including stem cell therapy The importance of nutrition and stress management in hair health How personalized treatment plans can help effectively ...
Mar 24, 2026•1 hr 2 min•Ep. 146
Send us Fan Mail In this episode, Dr. Jaclyn and Jenn Pike explore the complexities of women's health, particularly in relation to exercise, nutrition, and hormonal balance. Jenn also shares her journey from working with professional athletes to focusing on everyday women. This episode also highlights: The evolution of women's fitness goals How stress and inflammation affect overall well-being The role of recovery, nutrition, and self-care The pressures modern women face and how a supportive env...
Mar 17, 2026•52 min•Ep. 145
Send us Fan Mail In this insightful episode, Dr. Mariza Snyder and Dr. Jaclyn Smeaton delve into the often-overlooked topic of perimenopause, shedding light on its complexities and the challenges women face during this transitional phase. This episode also explores: The role of estrogen in insulin sensitivity and how fluctuations can lead to weight gain, cravings, and muscle loss Recognizing the signs of perimenopause, which can often be subtle and easily dismissed The need for better education ...
Mar 10, 2026•59 min•Ep. 144
Send us Fan Mail In this engaging episode, Dr. Jaclyn Smeaton and Dr. Darshan Shah explore the evolution of healthcare towards a more patient-centered, data-driven approach, particularly in the realm of longevity medicine. This episode also covers: The impact of data and Artificial Intelligence (AI) on healthcare How seeking knowledge about their health data can empower patients Challenges and opportunities in modern medicine, including the shift towards personalized care The importance of proac...
Mar 03, 2026•1 hr 4 min•Ep. 143
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Feb 24, 2026•47 min•Ep. 142
Send us Fan Mail In this episode, Kiran Krishnan discusses the critical role of the skin microbiome in overall health, emphasizing its impact on skin barrier function and the consequences of dysbiosis. Dr. Smeaton and Kiran also discuss: The connection between gut health and skin conditions like acne and atopic dermatitis Personal care products and lifestyle choices that can affect skin health Foundational strategies for maintaining a healthy skin microbiome Microbial migration from the skin and...
Feb 17, 2026•46 min•Ep. 141
Send us Fan Mail In this conversation, Dr. Jaclyn Smeaton and Dr. Molly Maloof discuss the critical role of relationships and social connections in promoting longevity and overall health. This episode also explores: The science behind mind-body medicine The impact of isolation on health, particularly chronic health issues Understanding relationships and how they can impact hormonal balance Insights on how chronic stress and disconnection affect physiological health Practical strategies for physi...
Feb 10, 2026•45 min•Ep. 140
Send us Fan Mail In this conversation, Dr. Jaclyn Smeaton and Cynthia Thurlow discuss critical aspects of women's health, focusing on ovarian senescence, perimenopause, and the impact of lifestyle choices on hormonal health. This episode also covers: Understanding ovarian senescence and how it impacts women’s biological clock Menstrual cycles as vital signs of health, not just inconveniences The necessity of addressing symptoms that women often accept as normal How strength training, intermitten...
Feb 03, 2026•36 min•Ep. 139
Send us Fan Mail In this conversation, Dr. Joanna Matras-Godziejewicz discusses the essential components of building a hormone dispensary and emphasizes the importance of understanding the hormone hierarchy. This discussion also explores: Various products and ingredients that can support women's health, insulin levels, and sleep issues The utility of the DUTCH Test in providing precise hormonal assessments Critical aspects of hormone health, particularly during perimenopause The importance of qu...
Jan 27, 2026•44 min•Ep. 138
Send us Fan Mail In this episode, Dr. Jennifer Simmons, Mark Newman, MS, and Dr. Jaclyn Smeaton discuss advancements in breast cancer screening, estrogen and breast cancer, and the gaps in provider education regarding hormone therapy. This conversation also highlights: The implications of removing the “black box” warning from menopausal estrogen products Misconceptions surrounding estrogen and breast cancer risk The nuances of hormone therapy during cancer treatment Innovative breast cancer scre...
Jan 20, 2026•51 min•Ep. 137
Send us Fan Mail In this conversation, Dr. Lucky Sekhon discusses the significance of Anti-Mullerian Hormone (AMH) levels in fertility and the release of her new book The Lucky Egg . This episode also explores: The role of mental health in fertility journeys How education and resources can empower individuals facing fertility challenges AMH and its importance in understand egg retrieval success Simplifying complex fertility topics with her book The Lucky Egg Self-advocacy in fertility care Show ...
Jan 13, 2026•45 min•Ep. 136
Send us Fan Mail In this conversation, Dr. Jaclyn Smeaton, Mark Newman, MS, and Dr. Kara Fitzgerald discuss her groundbreaking work on biological age reversal through dietary patterns and lifestyle interventions. This episode also explores: The role of epigenetics, polyphenols, and urolithin A in longevity How dietary patterns can influence biological age The impact of stress on hormonal health and methylation Nutrition and lifestyle as important parts of functional medicine How lifestyle change...
Jan 06, 2026•49 min•Ep. 135
Send us Fan Mail In this episode, Dr. Jaclyn Smeaton and Mark Newman, MS, Founder and CEO of Precision Analytical,, reflect on the significant developments at DUTCH over the past year, including educational initiatives, peer-reviewed research publications, and enhancements to the DUTCH Report. Mark Newman and Dr. Smeaton also discuss: The updated DUTCH Report and the importance of simplifying hormone testing and interpretation Improving hormone therapy practices through education, including educ...
Dec 23, 2025•50 min•Ep. 134
Send us Fan Mail In this engaging episode, Dr. Margaret Beeson shares her extensive journey in naturopathic medicine, highlighting the importance of understanding the underlying causes of health issues, particularly in women. Dr. Beeson and Dr. Smeaton also discuss: The rising levels of stress in modern society, especially post-COVID, and how it manifests in various health issues How small lifestyle and dietary changes can help to manage stress The importance of building strong patient-provider ...
Dec 16, 2025•1 hr 5 min•Ep. 133
Send us Fan Mail In this conversation, Dr. Amy Killen discusses her exploration of hormone optimization therapy and the evolving landscape of women's health. Dr. Killen and Dr. Smeaton also discuss: The multifaceted impact of progesterone and estrogen on women's health, particularly in relation to brain and bone health Multi-omic studies and how they can aid in understanding longevity Ongoing research in ovarian aging and the role of ovarian aging in women's health The potential of stem cell the...
Dec 02, 2025•1 hr 2 min•Ep. 132
Send us Fan Mail In this episode, Dr. Andrew Rostenberg discusses the intricate relationship between neurotransmitters, hormones, and mental health, emphasizing the role of the DUTCH Test in assessing these factors. This episode also highlights: Hormonal fluctuations and their impact on mood The intricate relationships between detoxification, gut health, hormones, and neurotransmitters The bell curve model to explain neurotransmitter levels, particularly dopamine and estrogen and their influence...
Nov 25, 2025•55 min•Ep. 131
Send us Fan Mail In this episode, Dr. Justin Houman discusses the importance of men's health, particularly focusing on urology, sexual health, and hormonal health. He highlights the increasing prevalence of low testosterone in younger men and the lifestyle factors contributing to this trend. The conversation also highlights: Essential lifestyle changes that can improve fertility and overall health The significance of vasectomy as a male contraceptive option The intricate relationship between sle...
Nov 18, 2025•50 min•Ep. 130
Send us Fan Mail In this engaging conversation, Esther Blum and Dr. Jaclyn explore the complexities of hormonal changes during perimenopause and menopause, emphasizing the importance of nutrition, self-care, and the impact of stress and trauma on women's health. Esther and Dr. Jaclyn also discuss: Practical strategies for managing stress and maintaining hormonal balance Societal pressures women face regarding health and wellness The intricate relationship between cortisol, stress, and hormonal b...
Nov 11, 2025•1 hr 2 min•Ep. 129
Send us Fan Mail In this episode, Dr. Carrie Jones and Dr. Jaclyn Smeaton delve into the complexities of hormonal health, focusing on the DUTCH Test and its comprehensive approach to understanding hormones. This conversation also covers: The importance of clarity in hormone testing The DUTCH Test’s new interpretive framework called the DUTCH Dozen How chronic stress can impact metabolic health and the often-misunderstood nature of cortisol The significance of the cortisol awakening response and ...
Nov 04, 2025•1 hr 1 min•Ep. 128
Send us Fan Mail In this episode, Dr. Lucas Tims shares his journey into naturopathic oncology, focusing on prostate cancer. He discusses the increasing incidence of prostate cancer, the hormonal influences on the disease, and the importance of hormone testing. Dr. Tims and Dr. Smeaton also discuss: The complexity of cancer drivers, particularly mitochondrial dysfunction Integrative approaches to oncology, highlighting the need for a balance between conventional and naturopathic treatments The r...
Oct 28, 2025•53 min•Ep. 127
Send us Fan Mail In this episode, Dr. Staci Whitman discusses the critical connection between oral health and hormone health, emphasizing the importance of the oral microbiome in systemic health and fertility. This discussion also covers: The need for more awareness and testing of the oral microbiome How hormonal changes throughout life, including puberty, pregnancy, and menopause, impact oral health and microbiome balance How mouth breathing can lead to various health issues, including dental d...
Oct 21, 2025•1 hr 7 min•Ep. 126
