Welcome to The Dr. Hyman Show, the podcast helping you take ownership of your health and reimagine what’s possible. Hosted by Dr. Mark Hyman—physician, bestselling author, and pioneer in functional medicine—this show explores the most pressing issues of our time: chronic disease, nutrition, mental health, food policy, prevention, and longevity.
In a world where our food system fuels disease and conventional healthcare often overlooks root causes, Dr. Hyman delivers evidence-based insights and expert conversations that empower you to become the CEO of your own health.
The Dr. Hyman Show goes beyond the headlines to envision a future where our food and healthcare systems support vitality, reduce chronic disease, and protect the environment. Whether you’re looking for actionable protocols, deeper understanding, or meaningful conversations at the intersection of health, food, and policy, this podcast is your trusted guide.
Tune in, take the lead, and transform your health one episode at a time.
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This week, in a special holiday edition of The Dr. Hyman Show , I’m revisiting a powerful conversation with Dr. Aseem Malhotra, a leading cardiologist and advocate for ethical, evidence-based medicine, where we unpacked the uncomfortable truths about cholesterol, statins, and what really drives heart disease. Wishing you a peaceful holiday week. We unpack: • Why LDL cholesterol isn’t the whole story when it comes to heart disease • How reducing inflammation and insulin resistance can better prot...
Dr. Hyman, with Dr. Richard Johnson and Dr. Robert Lustig, explores how sugar, especially fructose and high-fructose corn syrup, triggers obesity and metabolic diseases by activating a biological "fat switch" and disrupting gut health. The discussion highlights sugar's detrimental effects on mental well-being, including depression and anxiety, and details an actionable sugar detox plan alongside lifestyle changes like exercise, sleep, and stress management. The episode concludes by identifying eight cellular processes fundamental to chronic disease, all fixable primarily through food.
Dr. Mark Hyman and Dr. Ezekiel Emanuel delve into practical strategies for longevity, highlighting that true wellness comes from simple, built-in habits rather than obsessive pursuits. They discuss the critical role of social relationships—from deep connections to casual interactions—as a powerful determinant of health, often more impactful than diet or exercise. The conversation also covers the importance of home cooking, avoiding ultra-processed foods, balanced exercise, effective sleep hygiene, making smart preventive choices, and finding profound meaning and purpose in life, alongside the need for healthcare system reform.
This episode reveals Dr. Mark Hyman's five pillars for optimal health in 2026: food as medicine, restorative sleep, stress mastery, daily movement, and periodic detox resets. He explains how diet profoundly impacts gene expression and overall biology, often more effectively than pharmaceuticals. The discussion also covers the critical role of sleep in hormone balance and performance, the pervasive damage of chronic stress, and the extensive benefits of exercise for longevity and functional strength, concluding with a detailed guide to his 10-day detox plan and post-detox food reintroduction strategies.
Every parent wants to feed their baby well—but finding clarity in today’s system isn’t always easy. In this episode of The Dr. Hyman Show , I sit down with Laura Modi, CEO and co-founder of Bobbie, to talk about the real challenges families face when it comes to feeding and why it so often feels overwhelming. Laura shares her personal journey, the moments that changed everything, and what she’s learned from supporting thousands of parents through this stage. Enjoy the full conversation on YouTub...
Imagine a small town where neighbors gather for every celebration, and people stay remarkably healthy simply because they’re deeply connected. Research shows that meaningful relationships—not achievement, diet, or even exercise—are the strongest predictor of long-term health and happiness, while loneliness can be as harmful as smoking two packs a day. Our social bonds influence gene expression, lowering stress and inflammation and activating the body’s natural healing pathways. By prioritizing k...
On this episode of The Dr. Hyman Show , I’m joined by Maria Menounos, journalist, actor, and founder of Heal Squad, to explore what it truly means to take ownership of your health. After years of pushing through nonstop stress and serious health challenges, Maria discovered that real healing starts with mindset, community, and self-advocacy. Watch the full conversation on YouTube or listen wherever you get your podcasts. We discuss: • How you can recognize early warning signs and take action bef...
Dr. Mark Hyman, joined by Dr. Izabella Wentz and Dr. Elizabeth Boham, uncovers the complex roots of chronic fatigue, from damaged mitochondria to adrenal dysfunction and chronic infections. They discuss how diet, stress management, sleep, and targeted nutrients can revive energy. The episode highlights functional medicine's comprehensive approach to identifying and treating these underlying issues for lasting health restoration.
Dr. Hyman and relationship expert Jillian Turecki explore why love often feels challenging, tracing relationship patterns back to childhood conditioning and unconscious fears. They discuss practical tools for emotional regulation, navigating conflict, healing heartbreak, and fostering trust through empathy and conscious communication. The episode emphasizes self-reflection, cultivating generosity, and making intentional choices to build secure, lasting relationships that contribute to overall well-being.
Dr. Hyman, Dr. Papanicolaou, and Dr. Geyer challenge the conventional view of high blood pressure, explaining it's a whole-body problem rooted in inflammation, insulin resistance, and lifestyle factors rather than just salt or "bad pipes." They advocate for a functional medicine approach that identifies and treats underlying causes such as poor diet, sleep apnea, nutritional deficiencies, and environmental toxins. The episode introduces the 10-day detox as a comprehensive strategy, alongside key supplements, exercise, stress management, and improved sleep, demonstrating how these foundational changes can effectively reverse or improve hypertension.
Dr. Mark Hyman and Dr. Martin Picard delve into the revolutionary concept of energy as the fundamental driver of life and health. They discuss how mitochondria, far beyond mere ATP production, are central to the body's communication and resilience. The "Energy Resistance Principle" is introduced, explaining how imbalances in energy flow contribute to chronic diseases, from mental health issues to metabolic disorders. The conversation highlights the critical role of lifestyle, stress management, and diet in optimizing mitochondrial function, and envisions future clinical practices using biomarkers like GDF-15 for personalized energy management.
This episode reveals how replacing processed school lunches with real, scratch-cooked meals significantly enhances children's behavior, academic achievement, and overall health, debunking common misconceptions about cost and palatability. Guests discuss the My Way Cafe model, proving healthy food is affordable and scalable, and highlight the powerful scientific link between nutrition and cognitive function. The conversation also delves into the complex policy battles, industry lobbying, and transformative initiatives like Big Green, emphasizing the critical role of food education in shaping healthier futures for children.
Most people think of skincare as surface-level. But what if true radiance starts with your gut, your sleep, and your daily rituals? On this episode of The Dr. Hyman Show , I’m joined by Miranda Kerr, founder of KORA Organics, to explore how she restored balance after years of gut and stress-related challenges—and how you can support your own skin, hormones, and longevity from the inside out. We talk about the science behind inflammation, toxin exposure, and the small, consistent choices that mak...
Dr. Mark Hyman, along with Drs. Jason Fung and Thomas Seyfried, delve into the "seed and soil" analogy of cancer, arguing that modern diets, chronic inflammation, and insulin resistance create an ideal internal environment for cancer growth. They explain how processed foods, sugar, and constant eating disrupt the gut microbiome and fuel cancer cells' reliance on fermentation, contrasting this metabolic view with the prevailing genetic theory. The discussion highlights the potential of fasting and ketogenic diets to lower insulin, induce cellular cleanup (autophagy), and effectively starve cancer cells by cutting off their primary fuel sources, glucose and glutamine.
Your brain doesn’t wait until old age to start changing. It’s being shaped right now by the choices you make every single day. On this episode of The Dr. Hyman Show , I’m joined by preventive neurologist Dr. Richard Isaacson—founder of RetainYourBrain , a free assessment platform empowering people to understand and improve their cognitive health. Dr. Isaacson was also recently featured in a CNN documentary highlighting his groundbreaking work on Alzheimer’s prevention. In our conversation, we di...
Milk has long been sold as the key to strong bones, but research challenges that claim: many people don’t tolerate dairy, calcium needs are lower than advertised, and higher milk intake doesn’t necessarily prevent fractures. Politics and industry marketing helped set “three glasses a day,” even though healthy bones depend more on overall diet and lifestyle—things like vitamin D, movement, and avoiding soda, excess sugar, and stress that drive calcium loss. Dairy may be helpful for some diets, bu...
Our food system is reaching a breaking point—and the warning signs are already on our plates. From disappearing crops to rising health costs, it’s clear that the way we grow and eat food can’t continue as it has. Today on The Dr. Hyman Show, I sit down with Sam Kass, former White House chef and senior policy advisor, to explore his new book The Last Supper: The Politics of the End of Food . We talk about what’s driving the crisis, what’s already being done to repair it, and how each of us can he...
Most people don’t realize that what happens in the mouth can ripple through the whole body. The balance of the oral microbiome—the community of bacteria living in our mouths—can either protect us or trigger widespread inflammation that affects the heart, joints, and brain. Hidden dental infections or mercury fillings can quietly drive fatigue, autoimmune issues, or dementia—and fixing the mouth often helps the rest of the body heal, too. The good news is that with simple steps like eating whole ...
My guest today on The Dr. Hyman Show, Dr. Tom Frieden has spent decades proving how small, smart changes can save millions of lives. We talk about his new book, The Formula for Better Health: How to Save Millions of Lives—Including Your Own —a fascinating look at what really works to prevent disease and rebuild public trust. We also dive into his See–Believe–Create framework—how it connects public policy with personal action to make prevention the easy choice. Catch the full conversation on YouT...
Dr. Mark Hyman, joined by Dr. George Papanicolaou and Dr. Cindy Geyer, delves into chronic inflammation as the root cause of conditions like osteoarthritis, autoimmune diseases, and Raynaud's Syndrome. They critique conventional symptom management and advocate for a functional medicine approach, emphasizing anti-inflammatory diets, lifestyle changes, and targeted supplements. The discussion also highlights the transformative potential of Prolozone therapy for joint pain and outlines the comprehensive 10-Day Detox plan for a total body reset.
Food is medicine isn’t a slogan—it’s how our bodies are designed to heal. My guest today, Autumn Smith, knows that better than anyone. After overcoming years of digestive and mental health struggles, she co-founded Paleo Valley and Wild Pastures to help others access truly nutrient-dense food. On this episode of The Dr. Hyman Show , we explore how regenerative farming restores both soil and human health, why food quality matters as much as food choice, and how regeneratively raised animal foods ...
Many communities face an uneven food landscape: plenty of cheap junk food, but few places to buy fresh, healthy food. This pattern—often called “food apartheid”—doesn’t happen by accident; it grows from redlining, unfair rules, and corporate control. The impacts are steep: higher rates of type 2 diabetes, kidney failure, and learning problems in Black, Latino, and Indigenous communities, along with unsafe conditions for farmworkers. These harms have a long history, and government subsidies and c...
Today we tackle Parkinson’s as a preventable epidemic—not an inevitable fate. I’m joined on The Dr. Hyman Show by two of the field’s top neurologists, Drs. Ray Dorsey and Michael Okun, co-authors of The Parkinson’s Plan , to unpack why cases are exploding and what we can do about it right now. We look at how toxins drive disease, why Parkinson’s goes far beyond dopamine, and the early signs most people miss—plus what you can do today to protect your brain. And we connect the dots between environ...
Our immune systems are under more pressure than ever—from processed diets, environmental toxins, stress, and fast-spreading infections—and the result is faster aging and greater vulnerability to disease. As we grow older, “zombie cells” spread inflammation throughout the body, weakening defenses and accelerating decline. But research shows we’re not powerless: the emerging science of immuno-rejuvenation reveals that we can retrain and rebuild our immunity. Through the right foods, lifestyle habi...
Obesity is often seen as a matter of willpower, but science tells a different story. My guest today, Dr. David Kessler—former FDA commissioner, lawyer, physician, and the man who took on Big Tobacco—explains why biology, not blame, drives our struggles with weight. On this episode of The Dr. Hyman Show , we talk about why weight struggles are so common today, what new drugs can and can’t do, and how his new FDA petition targets one of the biggest culprits: processed refined carbs. Catch the full...
Thyroid trouble often starts as a whisper—tiredness, stubborn weight, dry skin—until a closer look shows the tiny neck gland that sets the body’s “speed” is out of tune. Basic tests can miss the real issue, so checking active hormones and thyroid antibodies—and hunting for triggers like stress, gluten sensitivity, toxins, nutrient gaps, and gut imbalances—can reveal what’s really going on. When understood this way, thyroid health is no longer just about numbers on a lab report—it’s about restori...
For too long, psychiatry has treated mental illness as if it lives only in the brain. But what if the real story begins in the body? My guest today, Dr. Shebani Sethi, is a Clinical Associate Professor at Stanford and founding director of the Metabolic Psychiatry Program, the first clinic to unite psychiatry with nutrition and metabolism. On this revealing episode of The Dr. Hyman Show , we explore how shifts in metabolism affect the brain and why this whole-body lens could transform how we prev...
Many people feel caught in worry, fear, and constant striving—chasing achievements yet never feeling truly fulfilled. The restless “monkey mind” jumps from one thing to the next, amplifying stress and turning setbacks into heavy burdens. It doesn’t have to be that way, though. You can move from mindless tasks to a mindful purpose. The shift begins by setting a clear, heartfelt intention rooted in something bigger. When the focus moves from self-gain to contribution, the right people, resources, ...
Most women are told that midlife decline is inevitable—more aches, weaker bones, less strength. But is that really true? On this episode of The Dr. Hyman Show , I sit down with Dr. Vonda Wright, a double-board certified orthopedic surgeon and leading voice in women’s longevity and performance. She shares how muscle functions as medicine, how hormones shape longevity, and why women’s midlife health deserves a whole new conversation. Join us for the full conversation on YouTube, or listen wherever...
Many psychiatric labels—like bipolar disorder and schizophrenia—can obscure underlying biology, and symptom checklists often fail to explain or heal what’s really going on. Emerging evidence reframes mental illness as a problem of brain energy, mitochondria, and inflammation—shaped by insulin signaling, circadian rhythm disruption, the gut–brain axis, toxins, infections, and nutrient status. Metabolic interventions such as ketogenic nutrition, already established for epilepsy, show promise for r...
