In today's episode, I had the chance to speak to muscle physiology researcher and science communicator Dr. Lauren Colenso-Semple. Together, we unpack the common claims around hormones and training—from whether you should change your workouts based on your cycle, to the real effects of fasted cardio and birth control on performance and muscle growth. We also explore how menopause affects body composition, what the science actually supports when it comes to training differences between men and wom...
May 13, 2025•1 hr 24 min•Ep. 153
In this episode, I’m joined by Dr. Abbie Smith-Ryan—one of the leading researchers in exercise physiology and women’s metabolism—to unpack the science of how women should be training through perimenopause, postmenopause, and beyond. We dive into the physiological changes that impact body composition, performance, and recovery—and how to adjust training and nutrition to match. We discuss: How high-intensity interval training (HIIT) improves VO₂ max, fat oxidation, and muscle quality in women Whet...
May 06, 2025•1 hr 25 min•Ep. 152
This week in the studio, I'm joined by Dr. Nick Barringer—Army Ranger, performance nutrition expert, and one of the sharpest minds in military and metabolic health. Together, we cut through the noise around today's most controversial nutrition topics. If you’ve ever felt whiplash trying to make sense of conflicting headlines, this episode is your science-based compass. What’s really going on with artificial sweeteners like sucralose and aspartame? Are seed oils toxic—or just misunderstood? And w...
Apr 29, 2025•1 hr 42 min•Ep. 151
In this episode, I’m joined by Shaun Noorian—engineer, entrepreneur, and CEO of Empower Pharmacy, the largest compounding pharmacy in the world. With compounded GLP-1s making headlines and lawsuits from Big Pharma intensifying, Shaun joins me to pull back the curtain on the regulatory, financial, and ethical storm brewing behind the scenes. Are compounded GLP-1s legal? Safe? Who controls drug pricing in the U.S., and why are Americans paying 10x more than Europeans for the same medication? And m...
Apr 22, 2025•1 hr 15 min•Ep. 150
In this episode, I’m joined by Dr. Melanie Cree—physician-scientist, pediatric endocrinologist, and one of the leading researchers redefining how we understand and treat Polycystic Ovary Syndrome (PCOS). PCOS affects millions of women, yet it's still underdiagnosed, misunderstood, and often mistreated. Dr. Cree cuts through the confusion, offering a deeply scientific yet compassionate look at what’s really driving this complex condition—from insulin resistance and mitochondrial dysfunction to sk...
Apr 15, 2025•1 hr 45 min•Ep. 149
In this episode, I’m joined by Dr. Jocelyn Wittstein—orthopedic surgeon, sports medicine expert, and Associate Professor at Duke University—for a powerful and practical conversation about bone and joint health across the lifespan. From the challenges of frozen shoulder and arthritis to the truth about running and menopause hormone therapy, this episode is your definitive guide to staying strong, mobile, and pain-free well into your 40s, 50s, and beyond. We cover: Why your joints and bones start ...
Apr 08, 2025•1 hr 43 min•Ep. 148
In this episode, I’m joined by Dr. Shane Kronstedt—former Navy SEAL, physician, surgical resident, and most importantly, my husband—for a powerful conversation about discipline, resilience, and the real-life moments that define us. From his early years of martial arts and mixed martial arts to surviving Hell Week and life-or-death missions in Afghanistan and Uganda, Shane shares how pressure creates clarity, why mindset matters most, and what it truly means to lead by example. This deeply person...
Apr 01, 2025•1 hr 40 min•Ep. 147
Jeff Krasno’s personal health transformation—reversing diabetes, shedding 60 pounds, and reclaiming his health at age 50—is a masterclass in what he calls “good stress.” In this episode, we dive into the simple but powerful idea that discomfort might just be the medicine we all need. Jeff, the founder of Commune and host of the Commune podcast, shares how fasting, cold exposure, resistance training, and attention to modern habits helped him regain his energy, build muscle, and thrive. Together, ...
Mar 25, 2025•1 hr 47 min•Ep. 146
Nelson Vergel’s story is one of resilience, perseverance, and an unrelenting drive to defy the odds. In the mid-1980s, he was handed what many would have considered a death sentence—an HIV diagnosis at a time when there were no effective treatments, no clear answers, and little hope. Today, he is a beacon of knowledge and empowerment for those seeking to take control of their health, whether they are dealing with wasting conditions, hormone deficiencies, or simply aiming for peak performance. Ne...
Mar 18, 2025•1 hr 36 min•Ep. 145
Dr. James Hill—a expert on obesity, metabolism, and long-term weight management—joins me this week to unpack the biggest challenges in sustainable fat loss. Dr. Hill has spent decades researching weight control and the factors that determine whether people can keep weight off long-term. We discuss the science behind energy balance, metabolic flexibility, and why long-term weight loss is about more than just diet and exercise. He shares insights from his groundbreaking work with the National Weig...
Mar 11, 2025•1 hr 41 min•Ep. 144
In this episode, Dr. Abraham Morgentaler—an expert in urology and hormone health—helps unpack the biggest myths and misconceptions surrounding testosterone therapy for both men and women. He shares his pioneering research on testosterone replacement therapy, challenging outdated fears about its link to prostate cancer and highlighting the latest findings on how hormone therapy can impact overall health, libido, and longevity. The conversation explores the controversial history of testosterone in...
Mar 04, 2025•1 hr 54 min•Ep. 143
Misinformation in nutrition is rampant. From demonizing red meat to hyping plant-based diets, conflicting advice has left many people confused about what’s truly evidence-based. In this episode, I am joined by Dr. Bradley Johnston , an expert in evidence-based nutrition and public health policies, to separate fact from fiction. With nearly 200 peer-reviewed publications, Dr. Johnston has challenged conventional wisdom—including recommendations from major organizations like the World Health Organ...
Feb 25, 2025•1 hr 31 min•Ep. 142
In this episode, I sit down with Dr. Kristy Hamilton, a board-certified plastic surgeon, to explore the latest advancements in aesthetic medicine, the impact of social media on beauty standards, and the reality of breast implant illness. Dr. Hamilton shares her expert insights on facial rejuvenation, fat transfer, the safety of fillers, and new biostimulators while debunking common myths around plastic surgery. We also dive deep into the controversial rise of explant surgeries, the latest data o...
Feb 18, 2025•1 hr 47 min•Ep. 141
Today, I welcome Dr. Donald Layman back to The Dr. Gabrielle Lyon Show for a deep dive into his decades of protein research, the flaws in dietary guidelines, and the evolving landscape of nutrition. Together, we explore the real reasons behind the obesity epidemic, why decades of dietary advice have led us astray, and how we can reclaim metabolic health through high-quality protein intake. Dr. Layman shares compelling research on protein requirements, nutrient density, and how misleading narrati...
Feb 11, 2025•2 hr 2 min•Ep. 140
Today, I welcome ultra-endurance athlete and world record holder Zach Bitter to The Dr. Gabrielle Lyon Show for an insightful conversation on the extreme physical and mental demands of ultra-marathons. Zach shares his mindset strategies for overcoming the inevitable dark moments in long-distance races, including visualization techniques and the importance of mental resilience in performance. We also dive into personalized nutrition and training adaptations, as Zach details his transition from a ...
Feb 04, 2025•1 hr 50 min•Ep. 139
Today, I welcome Dr. Heather Leidy to The Dr. Gabrielle Lyon Show for an in-depth conversation about the evolving landscape of nutrition science. Together, they tackle pressing topics like the future of the U.S. Dietary Guidelines, the impact of protein timing, and the importance of protein quality in supporting health and mitigating frailty. Dr. Leidy highlights recent research that explores behavioral strategies for sustainable weight management, the role of animal-sourced foods in nutrient ad...
Jan 28, 2025•1 hr 35 min•Ep. 138
Dr. Stephan Van Vliet joins us for an enlightening exploration of nutrition, agriculture, and human health. Our discussion navigates the often-overlooked complexities of food production, examining the nutritional differences between pasture-finished and grain-finished beef. We also uncover how maternal nutrition might set the stage for children's future dietary preferences. Dr. Van Vliet introduces the intriguing concept of the food matrix, emphasizing the profound impact of bioactive compounds ...
Jan 21, 2025•1 hr 12 min•Ep. 137
In this episode of The Dr. Gabrielle Lyon Show, I sit down with my friend, Dr. Allison Brager, a neurobiologist, researcher, and active-duty U.S. Army neuroscientist whose work redefines what we know about sleep and human performance. Allison’s expertise goes beyond the usual advice about getting eight hours of sleep. Instead, we explore how to optimize performance and resilience when life doesn’t allow for a perfect sleep routine—something we can all relate to. Allison shares fascinating insigh...
Jan 14, 2025•1 hr 41 min•Ep. 136
In this episode of The Dr. Gabrielle Lyon Show , Dr. Gabrielle Lyon sits down with Dr. Susanna Søberg, a leading expert in cold exposure and metabolism. They dive deep into the science behind cold plunging, the benefits of brown adipose tissue (BAT), and how minimal doses of cold can dramatically improve metabolic health, mental resilience, and overall well-being. Dr. Søberg shares her personal journey from working as a nurse to becoming a PhD researcher in metabolism, uncovering the surprising ...
Jan 07, 2025•1 hr 37 min•Ep. 135
In this episode of The Dr. Gabrielle Lyon Show, I sit down with Dr. Faidon Magkos, a leading expert in obesity and metabolism at the University of Copenhagen, to tackle one of the most debated topics in nutrition science – the root causes of obesity. We dive into the contrasting theories of energy balance and the carbohydrate-insulin model, shedding light on what the latest research reveals – and what remains unknown. Dr. Magkos also discusses how environmental factors, genetics, and muscle heal...
Dec 31, 2024•1 hr 57 min•Ep. 134
Dr. Kevin Maki, renowned scientist and co-founder of multiple biomedical research centers, joins us to demystify the world of nutrition science. With a career spanning decades in epidemiology and clinical trials, Dr. Maki dives into the evidence behind red meat, cholesterol, saturated fats, and the impact of dietary habits on heart health. Discover the truth behind common misconceptions and gain clarity on making informed dietary choices. In This Episode: • What does the science really say about...
Dec 24, 2024•1 hr 57 min•Ep. 133
In this episode of The Dr. Gabrielle Lyon Show, I sit down with Dr. Mike Israetel, an exercise physiologist and co-founder of Renaissance Periodization, to break down the science of sustainable fat loss and muscle gain. We explore the essential strategies for transforming your physique without falling for quick fixes or fad diets. From macronutrient distribution to the critical role of resistance training, Dr. Israetel offers practical, science-backed guidance for anyone looking to optimize thei...
Dec 17, 2024•1 hr 51 min•Ep. 132
In this episode of The Dr. Gabrielle Lyon Show , Dr. Lyon is joined by Dr. Russell Surasky, a board-certified neurologist and addiction specialist, to discuss one of the most pressing issues of our time: addiction. With a deeply personal connection to the topic, Dr. Surasky sheds light on the reality of addiction as a chronic brain disease and dispels the myths that have fueled stigma for decades. Dr. Surasky explains how addiction fundamentally alters brain function, the role of genetic suscept...
Dec 10, 2024•1 hr 52 min•Ep. 131
Join Dr. Gabrielle Lyon and Dr Christie Ballantyne, one of the world’s leading cardiologists, for an insightful conversation on the science behind cardiovascular health, metabolic wellness, and disease prevention. In this episode, Dr. Ballantyne shares groundbreaking research, the role of genetics, and practical steps you can take to optimize heart health. Whether it’s through diet, exercise, or understanding your unique health profile, this discussion is packed with actionable strategies to hel...
Dec 03, 2024•1 hr 48 min•Ep. 130
Dive into an extraordinary conversation with Dr. Gabrielle Lyon and Dr. Jamie Baum, Associate Professor and Director of the Center for Human Nutrition at the University of Arkansas. In this episode, we explore revolutionary topics: The role of skeletal muscle in appetite regulation. Cutting-edge research on perimenopause and postmenopause nutrition. How dietary protein impacts health and weight management. Surprising findings on protein supplementation and sleep quality. The science behind muscl...
Nov 27, 2024•1 hr 40 min•Ep. 129
The Dietary Guidelines Are Failing Us In this episode of The Dr. Gabrielle Lyon Show, Dr. Lyon is joined by Dr. Donald Layman, a world-renowned expert in protein metabolism and a pioneer in the field of nutritional science. With over 20 years of mentorship between them, Dr. Layman and Dr. Lyon dive deep into the flaws, myths, and future of U.S. Dietary Guidelines, offering a clear path to better health through smarter dietary decisions. Dr. Layman shares his revolutionary perspective on why prot...
Nov 19, 2024•1 hr 24 min•Ep. 128
Testosterone Matters for Everyone In this episode of The Dr. Gabrielle Lyon Show, Dr. Lyon sits down with Shalin Shah, CEO of Marius Pharmaceuticals, to explore the science, benefits, and future of testosterone therapy. Shalin has been a driving force behind bringing Kyzatrex, an FDA-approved oral testosterone, to market—making testosterone therapy more accessible and effective for both men and women. From breaking down misconceptions to advocating for better access to hormone therapy, this conv...
Nov 15, 2024•1 hr 21 min•Ep. 127
Designing Confidence In this episode of The Dr. Gabrielle Lyon Show, Dr. Lyon sits down with Heidi Somers, the founder of Buffbunny Collection, a dynamic and empowering fitness and lifestyle brand that has taken the industry by storm. From growing up in a small town in Alaska to becoming a successful entrepreneur, Heidi’s journey is a testament to the power of resilience, self-belief, and authenticity. Heidi opens up about her humble beginnings, including her early struggles with weight and body...
Nov 12, 2024•1 hr 37 min•Ep. 126
Raising Healthy Athletes In this enlightening episode of the Dr. Gabrielle Lyon Show, we dive deep into the world of youth training and the crucial role it plays in long-term health and athletic development. Joined by Judd Leinhard, former Army Ranger, collegiate lineman, and expert in speed training, we explore how training children differs from adults, debunk common myths, and reveal the surprising truth about building strength and resilience in kids. We dive into: Why strength training and we...
Nov 05, 2024•1 hr 40 min•Ep. 125
In this episode of The Dr. Gabrielle Lyon Show, I sit down with Dr. Layne Norton, a scientist and nutrition expert, to unpack the complex truths behind obesity, weight management, and diet myths. Together, we discuss what truly drives weight gain beyond the “calories in vs. calories out” model, exploring the impacts of hormones, metabolic rates, and lifestyle choices. We dive into: - How the body processes carbs, fats, and proteins - Challenging the carb-insulin model of obesity - Practical tips...
Oct 29, 2024•2 hr 7 min•Ep. 124
