What if your immune cells came with a smart upgrade?In this episode of the DeSci Podcast, we speak with Dr. Henry Erdlei, medical doctor, cancer researcher, and founder of GoCart, a new cell therapy platform building safer, modular CAR-T therapies through decentralized science.Henry breaks down:* How CAR-T cell therapies work* The real-world risks of immune overactivation* Why cancer is hard to distinguish from healthy tissue* The problem with existing logic gates in cell therapies* His own inno...
Jul 01, 2025•42 min
What if you were told that your body is secretly responding to Wi-Fi signals you can't even feel?In episode 49 of the Molecule Podcast we meet Dr. Geoff Anders (Founder, Leverage) and Dr. Clarice D. Aiello (Quantum Engineer), to explore the cutting-edge field where quantum physics meets biology, revealing how the smallest particles in the universe might be controlling the largest processes in life itself. Whether you're a scientist, technologist, or simply curious about the quantum world around ...
Jun 24, 2025•58 min
What if science wasn’t locked in labs or universities? In episode 47 of the Molecule Podcast, we meet Juan Keymer, Assistant Professor, Shenzhen X-Institute who enlightens us on the existing academic pipeline and how it can be made more flexible with the advancement in AI, DeSci (Decentralized Science), Blockchain Innovation, Open Credentials and more. • Reimagining the future of Science with DeSci. • This is a deep, thoughtful, and radically hopeful conversation about the future of learning, re...
Jun 02, 2025•45 min
Over $2.2 billion in NIH research grants are frozen. Labs are going dark. What happens now? In Episode 46 of the Molecule Podcast, we speak with Aaron Weaver, Chief Commercial Officer at Molecule, about the ongoing NIH funding crisis, its global impact, and how decentralized science (DeSci) is becoming a critical alternative. Aaron brings a unique vantage point from the intersection of venture capital, biotech, and public science funding. This episode unpacks: • The real story behind the NIH fun...
May 22, 2025•44 min
What if your next spine surgery was coordinated by a DAO? In Episode 48 of the Molecule Podcast, we’re joined by Vincent Challier, spine surgeon and co-founder of SpineDAO, and Virginie Lafage, medical strategist and Core Team member, to explore how decentralized science can transform a field as specialized and critical—as spinal health. SpineDAO is building one of the first focused medical DAOs on the Bio Launchpad. In this episode, we cover: • Why spinal health is overlooked in innovation • Th...
May 14, 2025•59 min
What if we could reinvent intellectual property for science? In this episode of Molecule’s DeSci Podcast, Kevin Noessler - Product Head at Molecule - joins us to talk about the next frontier of DeSci Science: Proof of Invention. Kevin unpacks how Molecule is building infrastructure for decentralized IP creation, ownership, and attribution. This episode zooms in on how DeSci tools can validate and tokenize early-stage scientific ideas—before patents or papers. We cover: • Kevin’s background and h...
May 07, 2025•40 min
What if the future of science and biotech was built on legal frameworks that empower communities, not corporations? In Episode 44 of the Molecule Podcast, we sit down with Jesse Hudson — lawyer, anthropologist, and Chief Legal Architect at Molecule. Jesse is a pioneer in building legal infrastructure for decentralized science (DeSci), DAOs, and intellectual property (IP) tokenization. This episode dives deep into: - The failure of the current global IP system - IP as cultural infrastructure - IP...
Apr 15, 2025•1 hr 1 min
The psychedelic industry is booming, but a major battle is unfolding: Who will control the future of these powerful medicines? Will open science prevail, or will corporations dominate through patents? In this episode, we sit down with Graham Pechenik, a leading expert in psychedelic patent law, to unravel the complexities of intellectual property in the space.Graham Pechenik is the founder of Calyx Law, a law firm specializing in psychedelic and cannabis patents. With a background in neuroscienc...
Apr 02, 2025•1 hr 48 min
Biotech is at a crossroads—AI, intellectual property, and startups are reshaping the future. But who really controls the breakthroughs? In this episode, Sara Holland, an IP advisor, explores how patents impact biotech, the challenges startups face against big pharma, and whether AI will change everything.What You’ll Learn in This Episode:- The hidden barriers to biotech innovation- How AI is transforming drug discovery and synthetic biology- The role of patents in protecting—or stifling—progress...
Mar 26, 2025•1 hr 30 min
Welcome to another episode of the DeSci Podcast. Today, we are discussing a critical issue that affects over 30 million people in the United States—Rare Diseases. Despite being more prevalent than cancer and HIV combined, rare diseases remain underfunded, overlooked by Big Pharma, and trapped in a broken system.Our Guest: This episode features Ethan Perlstein, founder of CureTopia, an initiative using Decentralized Science (DeSci) and blockchain to revolutionize rare disease research. Why does t...
Mar 24, 2025•1 hr 1 min
Welcome to another episode of the DeSci Podcast! Today, we’re excited to host Joshua Bate, Founder of DeSciWorld. DeSciWorld is a community-driven initiative dedicated to facilitating the onboarding of individuals into the Decentralized Science (DeSci) space. It provides users with the tools to view, engage with, and understand everything happening in the world of decentralized science. In this episode, Joshua shares the vision behind DeSciWorld and its role as a global hub for the decentralized...
Sep 09, 2024•34 min•Ep. 38
In this episode, we're diving deep into Molecule's Catalyst, an incentive-driven funding system for basic research. We begin by exploring the significant challenges posed by traditional funding models. We then touch on the "Valley of Death"—a critical juncture where many groundbreaking ideas fail often due to a lack of financial support. We discuss why early-stage research often struggles to gain traction and the barriers that prevent innovative ideas from reaching their full potential. Catalyst...
Aug 19, 2024•1 hr 18 min•Ep. 37
In this episode, we have the pleasure of hosting Alok Tayi, the co-founder of Vibe Bio.Vibe Bio is a life science company dedicated to investing in biotech firms, with a special focus on rare and overlooked diseases. In this episode, Alok shares his personal story of how medical conditions in his family led to the creation of Vibe Bio, and how the company aims to identify diseases with unmet needs, leveraging AI to find medicines with the highest chances of providing cures. We discuss the comple...
Jul 23, 2024•50 min•Ep. 36
Welcome to another episode of the DeSci Podcast. Today, we're joined by Justin, Head of Growth at Hippocrat, a collaborative healthcare data protocol that aims to transform healthcare by empowering individuals to take control of their health data through blockchain and zero-knowledge proof technologies. In this episode, we discuss the importance of data sovereignty, exploring how Hippocrat's innovative approach ensures secure and private data management, enabling safe and transparent data sharin...
Jun 30, 2024•52 min•Ep. 35
In this episode we're joined by Dr. Sönke Bartling, Founder of Blockchain for Science, an initiative that aims to open up science and knowledge creation through web3. In this episode, we explore Decentralized Science (DeSci) and its potential to revolutionize research, publishing, and innovation! We dive deep into how blockchain technology can transform scholarly publishing by making it more transparent, efficient, and trustworthy. We also discuss how DeSci can address funding inequality by supp...
May 28, 2024•48 min•Ep. 34
In this episode, we discuss the problem of declining R&D efficiency with Dr. Jack Scannell, a scientist and entrepreneur who is well known for coining the term “Eroom’s law,” which highlights the decline in pharmaceutical research and development (R&D) productivity over several decades. In this episode, Jack sheds light on the root causes of this decline, beginning with a critique of the poor quality of diagnosis surrounding the R&D productivity problem. He also talks about the chall...
May 02, 2024•47 min•Ep. 33
Welcome to another episode of the DeSci Podcast. Today, we were joined by Jeffrey Koury, Director & Business Development Lead at ResearchHub, and Jonathan Heppner, Marketing & Social Media Lead. ResearchHub is a platform designed to accelerate the pace of scientific research by providing a modern mobile and web application where people can collaborate on scientific research more efficiently. It aims to make scientific research accessible, collaborative, and prioritized for everyone. In t...
Apr 09, 2024•1 hr 6 min•Ep. 32
Today we are delighted to host Seemay Chow, Co-founder and CEO of Arcadia Science, a for-profit research institute with a specific focus on novel model organisms that haven't been traditionally studied in the lab and translating discoveries into commercial ventures. In this episode, we discuss Arcadia’s mission, structure and approach, emphasizing the importance of providing scientists with the context needed to understand the practical applications of their research. Seemay explains how this ap...
Mar 23, 2024•50 min•Ep. 31
Welcome to another episode of the DeSci podcast. Today, we were joined by Alfred Brown, co-founder of Desci London, a community dedicated to transforming science through web3 technology. In this episode, we talked about the DeSci London conference (scheduled for Saturday, 23 Mar 2024, 09:30 - Sunday, 24 Mar 2024, 16:30 GMT). This two-day event aims to spotlight the transformative potential of blockchain technology in the field of science, covering agendas such as Longevity research, Rare disease...
Mar 09, 2024•1 hr 9 min
Welcome to another episode of the DeSci Podcast! Today, we are delighted to host Stuart Buck. Stuart serves as a Senior Advisor at the Social Science Research Council and is the Executive Director of the Good Science Project—an organization dedicated to enhancing the funding and practice of science. In this episode, Stuart addresses key challenges in the scientific landscape, such as bureaucratic obstacles to funding and the distinction between basic and applied science. He emphasizes the interc...
Jan 29, 2024•47 min•Ep. 29
Welcome to another episode of the DeSci Podcast! Today we were joined by Brian Margierski, Brian is the CEO and Founder of Cerebrum DAO, an open, global community that seeks to reimagine impact funding to advance brain longevity and accelerate solutions and cures to Alzheimer’s disease and other neurological disorders. In this episode, Brian delves into Cerebrum DAO, outlining its mission and commitment to advancing brain health research. He sheds light on the motivating factors behind his inter...
Jan 17, 2024•36 min•Ep. 28
In this episode, we're joined by Keith Comito, a computer programmer, mathematician, and President at Lifespan. Lifespan.io is a non-profit advocacy foundation dedicated to accelerating initiatives aimed at addressing age-related diseases and extending the healthy human lifespan. Extending the human lifespan has been a captivating and often controversial topic. Over the years, focus has shifted from merely treating end diseases to addressing the fundamental mechanisms of aging itself. In this ep...
Dec 01, 2023•36 min•Ep. 27
Welcome to another episode of the DeSci Podcast. Today, we had the privilege of having Michael Baran as our guest. Michael Baran, MBA, Ph.D. is Executive Director, WRDM, and partner at Pfizer Ventures. In this episode, Michael discusses the unique features of DeSci, highlighting how it is reshaping the scientific landscape and redefining traditional paradigms. We also explored the significant risks in early-stage science investment and discussed key factors deterring investors from entering the ...
Nov 14, 2023•40 min•Ep. 26
Welcome to another episode of the DeSci Podcast. Today, we were joined by Dr. Jocelynn Pearl, a biotech scientist and the co-founder of LabDAO, an online life science research community whose mission is to accelerate progress in the life sciences by making scientific tools more accessible. In this episode, Jocelynn shares insights on the factors and events that birthed the idea of Decentralized Biotech and the importance of incentivizing knowledge sharing so it becomes accessible to other resear...
Sep 20, 2023•42 min•Ep. 25
Welcome to another episode of the DeSci Podcast. Today, we were joined by Juan Benet, the founder of Protocol Labs, an open-source research, development, and deployment laboratory. In this episode, Juan shares the story of his journey, the origins of Protocol Labs, and how he got involved in building IPFS and Filecoin. We uncover the underlying issues hindering technological advancements and dive deep into the translational science problem which Juan Benet believes is the biggest challenge facin...
Sep 08, 2023•1 hr 55 min•Ep. 24
Welcome to another episode of The DeSci Podcast. Today, we're joined by Niklas Anzinger, the founder and GP of Infinita, the first VC fund based in a modern charter city (Prospera), investing in founders overcoming regulatory bottlenecks in bio-/healthtech, hardware & crypto-finance through network states & startup cities. In this episode, Niklas shares insights on Infinitia Funds and how it supports innovative ventures and technological startups. Niklas also sheds light on Prospera's mi...
Aug 12, 2023•56 min•Ep. 23
Welcome to another episode of the DeSci Podcast. Today, we were joined by Jesse Hudson, the Chief Legal Architect at Molecule, Chris Byrnes, an IP Legal Advisor also representing Molecule, and Benji Leibowitz, Product Manager at Molecule. The existing intellectual property (IP) system faces several challenges that hinder its effectiveness and innovation potential. Patent trolls, the system's lack of efficiency, and the high transaction costs associated with acquiring and enforcing IP rights furt...
Jul 27, 2023•1 hr 23 min•Ep. 22
Welcome to another episode of the DeSci Podcast! Today, we were joined by Ben Reinhardt, founder of Speculative Technologies, a nonprofit research organization that runs coordinated research programs to unlock groundbreaking innovations. In this episode, we explore the qualities that make funders exceptional and the key factors that contribute to successful startup grants. We also shed light on the social and financial asymmetries between grantor and grantee, highlighting their negative impact o...
Jul 18, 2023•52 min•Ep. 21
Welcome to another episode of the DeSci Podcast! We are excited to have Nadia Asparouhova, an independent researcher and author of "Working in Public: The Making and Maintenance of Open Source Software", as our guest today. In this thought-provoking episode, we delve into the world of early-stage science funding and philanthropy. We discuss the role philanthropy plays in society and how it has evolved over the years. We also explore new funding mechanisms that have emerged to revolutionize the l...
Jun 26, 2023•48 min•Ep. 20
Welcome to another episode of the DeSci Podcast. Today, we had the privilege of having Dr. Martin-Immanuel Bittner as our guest. He is the CEO of Arctoris, which is the world's first fully automated platform for drug discovery, focused on accelerating the drug discovery process. In this episode, we explore a variety of fascinating topics related to drug discovery. Dr. Bittner shares insights on the story behind building Arctoris and its mission to accelerate the drug discovery process. We also t...
Jun 15, 2023•34 min•Ep. 19
