The Curious Clinicians

The Curious Clinicians•www.curiousclinicians.com

The Curious Clinicians is a medical podcast that asks "why?". Why do diseases present in certain ways? What are the mechanisms of treatments we use? Why does the human body function as it does? Join us to explore these questions and many more.

Last refreshed: July 10th, 2025 at 7:54 AM ⓘ

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Episodes

Episode 10 - Metronidazole

Avi, Tony, and Hannah are back at it, investigating why metronidazole treats both bacterial and parasitic infections, why it's only effective against anaerobic organisms, and how this relates to the supposed disulfiram-like reaction. The episode opens with an important message from Dr. Mark Shapiro (host of the Explore The Space podcast) about VoteHealth 2020 . Here are some links for obtaining CE/MOC credits just for listening to this episode and to read the show notes on our website. You can a...

Sep 30, 2020•21 min

Episode 9 - Umami

Hannah, Tony, and Avi dig into the origins and mechanism of that most wondrous of flavors: umami. Show notes: https://curiousclinicians.com/?p=722 CE/MOC: https://vcu.cloud-cme.com/course/search?p=4000&curriculum=Curious%20Clinicians

Sep 16, 2020•19 min

Episode 8 - Dyspnea from Angina

The Curious Clinicians examine why coronary ischemia can present with dyspnea. Show notes: https://curiousclinicians.com/?p=888 CE/MOC: https://vcu.cloud-cme.com/course/search?p=4000&curriculum=Curious%20Clinicians

Sep 02, 2020•23 min

Episode 7 - (Ab)normal Saline

The Curious Clinicians dive into the history and physiologic effects of IV fluids and why saline is definitely not "normal". Show notes: https://curiousclinicians.com/?p=824 CE/MOC: https://vcu.cloud-cme.com/course/search?p=4000&curriculum=Curious%20Clinicians

Aug 19, 2020•19 min

Episode 6 - Azithromycin

Avi, Hannah, and Tony investigate why the antibiotic azithromycin has anti-inflammatory properties. Show notes: https://curiousclinicians.com/?p=741 CE/MOC: https://ce.vcuhealth.org/CuriousClinicians

Aug 05, 2020•24 min

Episode 5 - Contraction Alkalosis

Tony, Avi, and Hannah examine the mechanisms of contraction alkalosis as a result of diuretic use, as well as the roles of chloride and a protein that none of them had previously heard of: pendrin. Show notes: http://curiousclinicians.com/?p=788 CE/MOC: https://ce.vcuhealth.org/CuriousClinicians

Jul 22, 2020•30 min

Episode 4 - Digitalis and Van Gogh

Hannah, Tony, and Avi dive into the health and art of Vincent Van Gogh. Was he treated with digitalis? Was he "dig toxic" and did this influence his color palette? Show notes: https://curiousclinicians.com/?p=311 CE/MOC: https://vcu.cloud-cme.com/default.aspx?p=4000&curriculum=Curious%20Clinicians

Jul 08, 2020•18 min

Episode 3 - TMP/SMX and Creatinine

On this episode of the The Curious Clinicians, Tony, Avi, and Hannah explore why trimethoprim/sulfamethoxazole can cause an isolated rise in creatinine. Show notes: http://curiousclinicians.com/?p=561 CE/MOC: https://ce.vcuhealth.org/CuriousClinicians

Jun 24, 2020•22 min

Episode 2 - Cancer Hypercoagulability

Hannah, Avi, and Tony break down why cancer leads to a hypercoagulable state, recalling the story of Armand Trousseau and exploring the roles of tissue factor and evading the immune system. Show notes: https://curiousclinicians.com/?p=304 CE/MOC: https://vcu.cloud-cme.com/default.aspx?P=0&EID=18166

Jun 10, 2020•26 min

Episode 1 - Fingernail Clubbing

Do you miss digging into the “why” behind what we do every day in medicine? Join Hannah, Tony, and Avi in The Curious Clinicians podcast as they delve into "why", starting with episode 1: Why does fingernail clubbing happen in so many different diseases? Show notes: https://curiousclinicians.com/?p=481 CE/MOC: https://ce.vcuhealth.org/CuriousClinicians

Jun 03, 2020•21 min

0 - Introduction and Preview

In this preview of The Curious Clinicians, we provide an introduction to the podcast and a sneak peak at Episode 1! The full episode will be released June 3rd.

May 20, 2020•5 min

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