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Talking Precision Medicine

Genialiswww.genialis.com
Welcome to the Talking Precision Medicine podcast. In this series, we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host.
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Episodes

Tom Neyarapally, Archetype Therapeutics | A new paradigm for generative AI drug discovery: more accurate shots on a much wider goal | TPM podcast #47

Joining us on this episode is Tom Neyarapally , co-founder and CEO of Archetype Therapeutics, an exciting new AI-driven company in the drug discovery space. Archetype is an AI-native biotech pioneering the use of generative chemogenomics and patient clinicogenomic data to virtually screen billions of potential drug candidates each day. ⁠⁠TPM E47 highlights >⁠⁠⁠⁠⁠⁠⁠⁠ Episode 47 links: Archetype Therapeutics Tom Neyarapally on LinkedIn “Exploring a “Patient-First” Path in Drug Discovery” , a Li...

Jun 24, 202543 minSeason 8Ep. 6

Stéphane Budel, DeciBio | Precision medicine is our future and our fate | TPM podcast #46

Stéphane Budel , founding partner at DeciBio, joins the Talking Precision Medicine Podcast to explore the future of the field. He unpacks how liquid biopsy, multi-omics, and AI are opening new doors for personalized care, why the diagnostics business model is holding innovation back, and what it will take to make complex tech usable for clinicians and patients alike. ⁠TPM E46 highlights >⁠⁠⁠⁠⁠⁠⁠⁠ Episode 46 links: DeciBio Stephane Budel on LinkedIn DeciBio’s White Paper on AI in Drug Developm...

May 19, 202550 minSeason 8Ep. 5

Anna Berkenblit & Sudheer Doss, PanCAN | On a mission to beat an ignoble killer: pancreatic cancer | TPM podcast #45

Today’s guests are Anna Berkenblit , Chief Scientific and Medical Officer at the Pancreatic Cancer Action Network, and Sudheer Doss , Chief Business Officer at PanCAN. The Pancreatic Cancer Action Network is the leading organization dedicated to advancing progress against pancreatic cancer. It empowers patients and caregivers, drives early detection strategies, and revolutionizes the development of advanced and personalized treatments. TPM E45 highlights >⁠⁠⁠⁠⁠⁠⁠⁠ Episode 45 links: Anna Berke...

Apr 22, 202546 minSeason 8Ep. 4

Najat Khan | Radical Transformation: Becoming a Medicines Company with End-to-End AI | TPM #44

Today’s guest is Najat Khan , Chief R&D Officer and Chief Commercial Officer at Recursion Pharmaceuticals. Recursion is widely recognized as one of the most visible—and so far, most successful—companies to emerge from the tech-bio movement. Many consider it the current industry leader. It has become an iconic name in the field of artificial intelligence for drug discovery. TPM E44 highlights >⁠⁠⁠⁠⁠⁠⁠ Episode 44 links: Najat Khan on LinkedIn Recursion...

Mar 28, 202539 minSeason 8Ep. 3

Ryan Fukushima | Reinventing diagnostics: The superpower of not knowing what can’t be done | TPM #43

What a pleasure to welcome today’s guest, Ryan Fukushima , chief operating officer of TempusAI. Not only has Ryan helped build Tempus brick by brick from the earliest days, he is also CEO of Pathos AI, a biotech company using real world data and AI to develop true precision medicines. I don’t know how he juggles it all, but unless you’ve been hiding out these last few years, Tempus has become a household name in our industry, completing a highly successful IPO last year. But no need to take my w...

Feb 26, 202543 minSeason 8Ep. 2

The journey to the top of life sciences technology: a lifetime of listening and learning | Talking Precision Medicine #42

Today my guest is Joydeep Goswami , newly appointed President and CEO of the storied biotechnology company LGC. Joydeep is also a strategy advisor to Genialis. Join us as we discuss his remarkable career and lessons learned at each step of the way. Come on in and have a listen. Episode 42 links: ⁠⁠⁠⁠⁠⁠⁠TPM E42⁠⁠⁠ for highlights and links from this episode >⁠⁠⁠⁠⁠⁠ Tempus Announces a Collaboration With Genialis Genialis’ Upcoming Events...

Jan 31, 202548 minSeason 8Ep. 1

The view from 30,000: Healthcare & life science AI in the cloud | Talking Precision Medicine #41

This episode features a conversation with Shweta Maniar , who leads the Healthcare and Life Science effort at Google cloud. In just a few short years, artificial intelligence has gone from the stuff of hype and fairy tale to powerful and ubiquitous tools for all aspects of R&D and healthcare delivery. Google has been central to this sea change. I discuss with Shweta how her organization helps make these advanced capabilities available to the masses, and so much more. Join us! Episode 41 link...

Dec 18, 202437 minSeason 7Ep. 7

What’s in a digital twin? Inventing new kinds of AI for biomedicine | Talking Precision Medicine #40

Our guest this episode is Charles Fisher , co-founder and currently Chief Scientific Officer of Unlearn.AI. Unlearn has been a leader in the advancement of Digital Twins as a tool to drastically improve the efficiency of clinical trials. Not only a visionary scientist and trailblazing entrepreneur, Charles is fearless with his hot takes. So sit back and enjoy this free wheeling conversation! Episode 40 links: ⁠⁠⁠⁠⁠⁠TPM E40⁠⁠⁠ for highlights and links from this episode >⁠⁠⁠⁠ Potential of the X...

Nov 15, 202447 minSeason 7Ep. 6

Leave No Patient Behind—R&D Tools and Cutting Edge Diagnostics that Span the Globe | Talking Precision Medicine #39

What a genuine pleasure to sit with Thierry Bernard , CEO of Qiagen. As I told Thierry, Qiagen is a truly iconic brand for anyone who came up through molecular biology laboratories in the past 30 years. Their products were ubiquitous, and crucial, to the success of our research. In this conversation, Thierry talks about his global vision for precision medicine, and his mantra that we leave no patient behind. Episode 39 links: ⁠⁠⁠⁠⁠TPM E39⁠⁠⁠ for highlights and links from this episode >⁠⁠⁠ Gen...

Oct 08, 202436 minSeason 7Ep. 5

Zola-007: Giving T-cells the license to kill | Talking Precision Medicine #38

What a pleasure to sit down with my long time colleague and friend, Art Krieg, to discuss his latest venture, Zola Therapeutics, and his adventures in the great outdoors. Art has launched and exited a number of innovative biotechs, each time delving deeper into mechanisms by which we can harness the immune system for therapeutic purposes. Join us as we discuss how — despite a well earned retirement — the siren song that led to Zola was strong enough to get Art back in the game. Episode 38 links:...

Aug 29, 202444 minSeason 7Ep. 4

Cell therapy for T-cell malignancies—the science and business of developing curative medicines for patients in need | Talking Precision Medicine #37

In this episode I chat with Dr Sarah Hein, co-founder and CEO of March Biosciences, a Houston Based biotech developing cell therapies for T-cell malignancies. Sarah is an old friend and colleague from our days as trainees at Baylor College of Medicine, where we both circulated among those with ambitions of entrepreneurship. Sarah has definitely made good in that regard, as a serial entrepreneur deeply enmeshed in Houston’s growing life sciences and healthtech ecosystem. Episode 37 links: ⁠⁠⁠⁠TPM...

Jul 22, 202439 minSeason 7Ep. 3

Tackling healthcare disparities and bridging the digital divide: it doesn’t have to be so hard | Talking Precision Medicine #36

This episode features two guests, Jennifer Goldsack and Yashoda Sharma , of the Digital Medicine Society, or DiMe. We’re going to get into the nitty gritty of healthcare disparities in terms of access and outcomes, and how digital solutions are a big part of the overall solution. Episode 36 links: ⁠⁠⁠TPM E36⁠⁠⁠ for highlights and links from this episode > Genialis’ Upcoming Events Genialis™ krasID...

May 24, 202444 minSeason 7Ep. 2

The Science and Art of De-risking Cancer Drug Development | Talking Precision Medicine #35

In this episode Genialis CEO Rafael Rosengarten sat down with Dr. Carolina Haefliger , head of translational medicine at Debiopharm, the privately held Swiss biopharma company focused on oncology drug development. They talked about de-risking promising new cancer drugs, and what it takes from the science to the team to the technologies. Episode 35 links: Visit ⁠⁠⁠ TPM E35 ⁠⁠⁠ for highlights and links from this episode > Learn more about Genialis™ krasID > New Genialis RNA Biomarker Accurat...

Apr 12, 202431 minSeason 7Ep. 1

Professional grade software — a key ingredient in cutting edge biomedical discovery | Talking Precision Medicine #34

Today we turn the mic around, as our guest Adam Stasio hosts an excellent podcast of his own. Adam’s day job, however, is running SciMed, a boutique life sciences software development company. Adam and Genialis CEO Rafael Rosengarten discuss the state of scientific software, the importance of agility and communication, and approaches to building a lasting company culture. Visit ⁠⁠ TPM E34 ⁠⁠ for highlights and links from this episode....

Dec 14, 202332 minSeason 6Ep. 6

New Medicines from Evolutionary Pathways: Using Comparative Genomics to Treat Human Disease | Talking Precision Medicine #33

Our guest today is Dr. Ashley Zehnder , co-founder and CEO of Fauna Bio. Fauna is a revolutionary young biotech company using comparative genomics of an array of non-traditional mammalian models to discover new therapeutic opportunities for people. What do ground squirrels have to do with treating battlefield trauma? Only one way to find out … Visit ⁠ TPM E33 ⁠ for highlights and links from this episode....

Oct 27, 202343 minSeason 6Ep. 4

AI and Ethics in Healthtech: Who is Innovating Most? | Talking Precision Medicine #31

In this episode, Genialis CEO Rafael Rosengarten speaks with BCG management consultant and healthcare innovation expert Amy MacDougall . They discuss emerging trends in healthcare, the role of AI, ethics and more, as well as BCG’s recently released 50 Most Innovative Companies List. Visit TPM E31 for highlights and links from this episode.

Jun 29, 202335 minSeason 6Ep. 3

People first: building a company that inspires impactful work | Talking Precision Medicine #30

This episode, Genialis’ thirtieth, is a bit different from the previous ones. CEO Rafael Rosengarten has not one, not two, but three guests, including the entire leadership team at Genialis . The gang discusses Genialis’ twin quests to build a great place to work and a business that makes a positive impact on the world. Visit TPM E30 for highlights and links from this episode....

May 31, 202351 minSeason 6Ep. 2

Communication, the key to building community | Talking Precision Medicine #29

Our guest this episode is Dr. Susanna Harris , community lead at Vibe Bio. Susanna is a dedicated scientific communicator and an outspoken advocate for the mental health of PhD students and other science researchers. She has chronicled her journey from the academic lab bench to a venture incubator to a promising biotech company for a substantial social media following, and joins us today to dive into these topics and more. Visit TPM E29 for highlights and links from this episode....

Jan 26, 202345 minSeason 6Ep. 1

A new way to finance drug development, for rare disease and beyond | Talking Precision Medicine #28

In this episode, our host and Genialis CEO Rafael Rosengarten spotlights Vibe Bio. Vibe Bio is a new biotech aiming to disrupt how we finance drug development through stakeholder communities and cryptocurrency, starting in the rare disease arena. Our guest is Alok Tayi , co-founder and CEO of Vibe. Alok is a successful serial entrepreneur and a rare disease community member. Visit TPM E28 for highlights and links from this episode....

Nov 30, 202246 minSeason 5Ep. 3

What’s in a Name?: Endpoint Health’s Patient-Centric Northstar | Talking Precision Medicine #27

This episode features Jason Springs, co-founder and CEO of Endpoint Health, an ascendant precision therapeutics company. Jason is a serial entrepreneur, who with the co-founders of his previous company, is building Endpoint Health to bring together under one roof the data science, diagnostics and therapeutics necessary to achieve truly personalized care. Visit TPM E27 for highlights and links from this episode.

Jun 27, 202243 minSeason 5Ep. 2

Taking charge of your health future with wearables and AI | Talking Precision Medicine #26

In this episode 26, our host Rafael sits down with Harry Glorikian . Harry is an investor, author, podcaster and veteran of the healthtech industry. Harry walks us through his latest book, The Future You , and expounds on the ways that wearable devices, personal health data and artificial intelligence are changing healthcare as we know it. Visit TPM E26 for highlights and links from this episode....

Feb 28, 202234 minSeason 5Ep. 1

Fostering Patient Journeys Around the World | Talking Precision Medicine #24

Our guest is Dr. Angeli Moeller , Head of Pharma International Informatics at Roche. Angeli and our host, Rafael, discuss data science in the big pharma leagues; geek out on data standards; and dive deep on patient data rights and barriers to care. Visit TPM E24 for highlights and links from this episode.

Jul 28, 202141 minSeason 4Ep. 5

Ethics and Policies of Precision Medicine on the Global Stage | Talking Precision Medicine #22

Our guests for this episode of Talking Precision Medicine are Elissa Prichep and Cameron Fox of the World Economic Forum. Elissa and Cameron take us through the W.E.F’s precision medicine initiative, and explain how anticipating ethical tensions is key to envisioning policies for precision medicine across the globe. Visit TPM E22 for highlights and links from this episode....

Nov 19, 202050 minSeason 3Ep. 6

Rebooting generics to fight cancer | Talking Precision Medicine #21

Reboot Rx is a different kind of biotech startup. Reboot’s mission is to find generic non-cancer drugs that can benefit cancer patients quickly and affordably. And as a not-for-profit, Reboot can stay focused on its mission. Given the number of paradigms Reboot hopes to shift at once, we decided to talk with all three co-founders: CEO Laura Kleiman , COO & CTO Pradeep Mangalath and CSO Catherine Del Vecchio Fitz . Each one provides perspective on their part of the puzzle. Visit TPM E21 for h...

Aug 31, 202051 minSeason 3Ep. 5

Stopping sepsis in its tracks… oh, and COVID19 too! | Talking Precision Medicine #20

Today Rafael is joined by Dr. Sarma Velamuri , founder and CEO of Luminare. Luminare is a Houston-based digital health company dedicated to ending sepsis—the number 1 cause of death in US hospitals. In the conversation that follows, Dr. Velamuri explains how Luminare saves lives by streamlining hospital workflows, and by changing the behaviors of nurses and doctors. They’ve also made a giant leap into covid tracking, emerging as national leaders on this front. Visit TPM E20 for highlights and li...

Jun 11, 202047 minSeason 3Ep. 4

Meet the viruses that are saving lives with Rob McBride | Talking Precision Medicine #19

Today’s news is dominated by the corona virus and COVID-19 pandemic. Rightfully so. But today we’re bringing you a story of another class of viruses, called Phage. Phage are viruses that find and kill bacteria, and Felix is a Bay Area biotech harnessing the power of phage to fight the scourge of antibiotic resistant infections. So join our conversation with founder and CEO, Dr. Rob McBride, from wherever you have socially distanced yourself or locked down on quarantine, and learn about the virus...

Mar 17, 202036 minSeason 3Ep. 3

DNA solves the oldest cold case with David Mittelman | Talking Precision Medicine #18

Today’s episode is a bit different — different in that we are rejoined by a previous guest — David Mittelman . David is CEO of Othram, the first genomics-based forensics company. The audience response to our first conversation was so overwhelming we wanted to have David back on. And the timing couldn’t be better. Since our last chat, David and Othram have been all over the news, and have launched a new database product. Visit ⁠TPM E18 for highlights and links from this episode....

Mar 04, 202033 minSeason 3Ep. 2
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